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Search results 101 to 195 out of 195 for Smyd1

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0.027s
Type Details Score
GXD Expression  
Probe: MGI:6887674
Assay Type: RNA in situ
Annotation Date: 2022-03-10
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1634614
Pattern: Not Specified
Stage: TS14
Assay Id: MGI:6887749
Age: embryonic day 9.0
Image: 1B left
Specimen Label: 1B left
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:6887674
Assay Type: RNA in situ
Annotation Date: 2022-03-10
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1634614
Pattern: Not Specified
Stage: TS14
Assay Id: MGI:6887749
Age: embryonic day 9.0
Image: 1B right
Specimen Label: 1B right
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:6887674
Assay Type: RNA in situ
Annotation Date: 2022-03-10
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1634615
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:6887749
Age: embryonic day 9.5
Image: 1C left
Specimen Label: 1C left
Detected: true
Specimen Num: 5
GXD Expression  
Probe: MGI:6887674
Assay Type: RNA in situ
Annotation Date: 2022-03-10
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1634615
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:6887749
Age: embryonic day 9.5
Image: 1C right
Specimen Label: 1C right
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:4429852
Assay Type: RNA in situ
Annotation Date: 2023-04-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1611719
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:7464048
Age: embryonic day 11.5
Specimen Label: Table S1 E11.5
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:6887674
Assay Type: RNA in situ
Annotation Date: 2022-03-10
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1635013
Pattern: Not Specified
Stage: TS13
Assay Id: MGI:6887749
Age: embryonic day 8.5
Image: 1A left
Specimen Label: 1A left
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:6887674
Assay Type: RNA in situ
Annotation Date: 2022-03-10
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1635013
Pattern: Not Specified
Stage: TS13
Assay Id: MGI:6887749
Age: embryonic day 8.5
Image: 1A right
Specimen Label: 1A right
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:6887674
Assay Type: RNA in situ
Annotation Date: 2022-03-10
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1635014
Pattern: Not Specified
Stage: TS14
Assay Id: MGI:6887749
Age: embryonic day 9.0
Image: 1B left
Specimen Label: 1B left
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:6887674
Assay Type: RNA in situ
Annotation Date: 2022-03-10
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1635014
Pattern: Not Specified
Stage: TS14
Assay Id: MGI:6887749
Age: embryonic day 9.0
Image: 1B right
Specimen Label: 1B right
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:6887674
Assay Type: RNA in situ
Annotation Date: 2022-03-10
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1635015
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:6887749
Age: embryonic day 9.5
Image: 1C left
Specimen Label: 1C left
Detected: true
Specimen Num: 5
GXD Expression  
Probe: MGI:6887674
Assay Type: RNA in situ
Annotation Date: 2022-03-10
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1635015
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:6887749
Age: embryonic day 9.5
Image: 1C right
Specimen Label: 1C right
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:4429852
Assay Type: RNA in situ
Annotation Date: 2010-02-24
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1618415
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:4429946
Age: embryonic day 9.5
Specimen Label: Table S4 - E9.5
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:4429852
Assay Type: RNA in situ
Annotation Date: 2010-02-24
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1618417
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:4429946
Age: embryonic day 10.5
Specimen Label: Table S4 - E10.5
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:4429852
Assay Type: RNA in situ
Annotation Date: 2010-02-24
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1618419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:4429946
Age: embryonic day 11.5
Specimen Label: Table S4 - E11.5
Detected: true
Specimen Num: 7
Publication
First Author: Phan D
Year: 2005
Journal: Development
Title: BOP, a regulator of right ventricular heart development, is a direct transcriptional target of MEF2C in the developing heart.
Volume: 132
Issue: 11
Pages: 2669-78
Publication
First Author: Hwang I
Year: 1995
Journal: Immunogenetics
Title: Bop: a new T-cell-restricted gene located upstream of and opposite to mouse CD8b.
Volume: 42
Issue: 5
Pages: 353-61
Publication  
First Author: Brown MA
Year: 2006
Journal: Mol Cancer
Title: Identification and characterization of Smyd2: a split SET/MYND domain-containing histone H3 lysine 36-specific methyltransferase that interacts with the Sin3 histone deacetylase complex.
Volume: 5
Pages: 26
Publication
First Author: Kwon C
Year: 2009
Journal: Nat Cell Biol
Title: A regulatory pathway involving Notch1/beta-catenin/Isl1 determines cardiac progenitor cell fate.
Volume: 11
Issue: 8
Pages: 951-7
Publication
First Author: Gladman JT
Year: 2013
Journal: PLoS One
Title: Age of onset of RNA toxicity influences phenotypic severity: evidence from an inducible mouse model of myotonic dystrophy (DM1).
Volume: 8
Issue: 9
Pages: e72907
Publication
First Author: Diehl F
Year: 2010
Journal: PLoS One
Title: Cardiac deletion of Smyd2 is dispensable for mouse heart development.
Volume: 5
Issue: 3
Pages: e9748
Publication
First Author: Smith SJ
Year: 2016
Journal: Dev Biol
Title: The cardiac-restricted protein ADP-ribosylhydrolase-like 1 is essential for heart chamber outgrowth and acts on muscle actin filament assembly.
Volume: 416
Issue: 2
Pages: 373-88
Publication
First Author: Poltorak A
Year: 2001
Journal: J Immunol
Title: A point mutation in the IL-12R beta 2 gene underlies the IL-12 unresponsiveness of Lps-defective C57BL/10ScCr mice.
Volume: 167
Issue: 4
Pages: 2106-11
Publication
First Author: Saita S
Year: 2014
Journal: J Biol Chem
Title: Role of the ANKMY2-FKBP38 axis in regulation of the Sonic hedgehog (Shh) signaling pathway.
Volume: 289
Issue: 37
Pages: 25639-54
Publication
First Author: Niu Z
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Serum response factor orchestrates nascent sarcomerogenesis and silences the biomineralization gene program in the heart.
Volume: 105
Issue: 46
Pages: 17824-9
Publication
First Author: Nakazawa M
Year: 2011
Journal: J Mol Cell Cardiol
Title: Inositol 1,4,5-trisphosphate receptors are essential for the development of the second heart field.
Volume: 51
Issue: 1
Pages: 58-66
Publication
First Author: Potthoff MJ
Year: 2007
Journal: Mol Cell Biol
Title: Regulation of skeletal muscle sarcomere integrity and postnatal muscle function by Mef2c.
Volume: 27
Issue: 23
Pages: 8143-51
Publication
First Author: Diehl AG
Year: 2006
Journal: Invest Ophthalmol Vis Sci
Title: Extraocular muscle morphogenesis and gene expression are regulated by Pitx2 gene dose.
Volume: 47
Issue: 5
Pages: 1785-93
Publication
First Author: Cattaneo P
Year: 2022
Journal: Nat Commun
Title: DOT1L regulates chamber-specific transcriptional networks during cardiogenesis and mediates postnatal cell cycle withdrawal.
Volume: 13
Issue: 1
Pages: 7444
Publication
First Author: Wajapeyee N
Year: 2013
Journal: Genes Dev
Title: Oncogenic RAS directs silencing of tumor suppressor genes through ordered recruitment of transcriptional repressors.
Volume: 27
Issue: 20
Pages: 2221-6
Publication
First Author: Weng J
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Deletion of G protein-coupled receptor 48 leads to ocular anterior segment dysgenesis (ASD) through down-regulation of Pitx2.
Volume: 105
Issue: 16
Pages: 6081-6
Publication
First Author: Zoupa M
Year: 2018
Journal: BMC Genomics
Title: Gene expression profiling in the developing secondary palate in the absence of Tbx1 function.
Volume: 19
Issue: 1
Pages: 429
Publication
First Author: Rajan S
Year: 2012
Journal: Physiol Genomics
Title: Analysis of early C2C12 myogenesis identifies stably and differentially expressed transcriptional regulators whose knock-down inhibits myoblast differentiation.
Volume: 44
Issue: 2
Pages: 183-97
Publication
First Author: Uribe V
Year: 2014
Journal: Development
Title: Arid3b is essential for second heart field cell deployment and heart patterning.
Volume: 141
Issue: 21
Pages: 4168-81
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication
First Author: Shimizu H
Year: 2013
Journal: PLoS One
Title: The AERO system: a 3D-like approach for recording gene expression patterns in the whole mouse embryo.
Volume: 8
Issue: 10
Pages: e75754
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
Publication        
First Author: GO Central curators, GOA curators, Rhea curators
Year: 2020
Title: Automatic Gene Ontology annotation based on Rhea mapping
Publication
First Author: Ko MS
Year: 2000
Journal: Development
Title: Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development.
Volume: 127
Issue: 8
Pages: 1737-49
Publication
First Author: Yokoyama S
Year: 2009
Journal: Dev Cell
Title: A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58.
Volume: 17
Issue: 6
Pages: 836-48
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations for FANTOM2 data
Publication      
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
Publication        
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
Publication        
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
UniProt Feature
Begin: 1
Description: Histone-lysine N-methyltransferase Smyd1
Type: chain
End: 490
HT Experiment
Series Id: GSE71679
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: ArrayExpress
Publication
First Author: Sirinupong N
Year: 2010
Journal: J Biol Chem
Title: Crystal structure of cardiac-specific histone methyltransferase SmyD1 reveals unusual active site architecture.
Volume: 285
Issue: 52
Pages: 40635-44
Protein
Organism: Mus musculus/domesticus
Length: 490  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 456  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 477  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 461  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 21  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 58  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 69  
Fragment?: false
Publication
First Author: Just S
Year: 2011
Journal: J Cell Sci
Title: The myosin-interacting protein SMYD1 is essential for sarcomere organization.
Volume: 124
Issue: Pt 18
Pages: 3127-36
GXD Expression
Probe: MGI:6887676
Assay Type: Immunohistochemistry
Annotation Date: 2022-03-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3268828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6887757
Age: postnatal
Image: 4E
Note: Co-expression of Smyd1 and Ash2l was noted in the nuclei and cytoplasm of cardiomyocytes.
Specimen Label: 4E
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:6887676
Assay Type: Immunohistochemistry
Annotation Date: 2022-03-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3268828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6887757
Age: postnatal
Image: 4E
Note: Co-expression of Smyd1 and Ash2l was noted in the nuclei and cytoplasm of cardiomyocytes.
Specimen Label: 4E
Detected: true
Specimen Num: 1
Publication
First Author: Ye X
Year: 2016
Journal: PLoS One
Title: SMYD1, an SRF-Interacting Partner, Is Involved in Angiogenesis.
Volume: 11
Issue: 1
Pages: e0146468
Protein Domain
Type: Domain
Description: This entry represents the SET domain of SET and MYND domain-containing protein 1 (SMYD1). SMYD1 functions as a histone methyltransferase and regulates downstream gene transcription. It methylates histone H3 at 'Lys-4' (H3K4me), seems able to perform both mono-, di-, and trimethylation. SMYD1 plays a critical role in cardiomyocyte differentiation, cardiac morphogenesis and myofibril organisation, as well as in the regulation of endothelial cells (ECs) [, ]. It is expressed in vascular endothelial cells, it has been shown that knockdown of SMYD1 in endothelial cells impairs EC migration and tube formation [].The SMYD family consists of five members including SMYD1/2/3/4/5. They contain two highly conserved structural and functional domains, the SET and MYND domains. The SET domain is involved in lysine methylation, while the MYND domain is involved in protein-protein interaction. They are essential in several mammalian developmental pathways [, , , ].
Publication
First Author: Li D
Year: 2009
Journal: Nucleic Acids Res
Title: SMYD1, the myogenic activator, is a direct target of serum response factor and myogenin.
Volume: 37
Issue: 21
Pages: 7059-71
Publication
First Author: Voelkel T
Year: 2013
Journal: Biochim Biophys Acta
Title: Lysine methyltransferase Smyd2 regulates Hsp90-mediated protection of the sarcomeric titin springs and cardiac function.
Volume: 1833
Issue: 4
Pages: 812-22
Publication
First Author: Du SJ
Year: 2014
Journal: Anat Rec (Hoboken)
Title: SMYD proteins: key regulators in skeletal and cardiac muscle development and function.
Volume: 297
Issue: 9
Pages: 1650-62
Publication
First Author: Mitchell LH
Year: 2016
Journal: ACS Med Chem Lett
Title: Novel Oxindole Sulfonamides and Sulfamides: EPZ031686, the First Orally Bioavailable Small Molecule SMYD3 Inhibitor.
Volume: 7
Issue: 2
Pages: 134-8
Publication
First Author: Sweis RF
Year: 2015
Journal: ACS Med Chem Lett
Title: Discovery of A-893, A New Cell-Active Benzoxazinone Inhibitor of Lysine Methyltransferase SMYD2.
Volume: 6
Issue: 6
Pages: 695-700
Publication  
First Author: Jarrell DK
Year: 2020
Journal: Vet Sci
Title: Characterizing the Role of SMYD2 in Mammalian Embryogenesis-Future Directions.
Volume: 7
Issue: 2
Protein
Organism: Mus musculus/domesticus
Length: 477  
Fragment?: false
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication
First Author: Carninci P
Year: 2000
Journal: Genome Res
Title: Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.
Volume: 10
Issue: 10
Pages: 1617-30
Publication  
First Author: Carninci P
Year: 1999
Journal: Methods Enzymol
Title: High-efficiency full-length cDNA cloning.
Volume: 303
Pages: 19-44
Publication
First Author: Shibata K
Year: 2000
Journal: Genome Res
Title: RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.
Volume: 10
Issue: 11
Pages: 1757-71
Publication
First Author: Katayama S
Year: 2005
Journal: Science
Title: Antisense transcription in the mammalian transcriptome.
Volume: 309
Issue: 5740
Pages: 1564-6
Publication
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
Publication
First Author: Huttlin EL
Year: 2010
Journal: Cell
Title: A tissue-specific atlas of mouse protein phosphorylation and expression.
Volume: 143
Issue: 7
Pages: 1174-89
Publication
First Author: Church DM
Year: 2009
Journal: PLoS Biol
Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.
Volume: 7
Issue: 5
Pages: e1000112