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Search results 201 to 261 out of 261 for Rnf11

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Type Details Score
GXD Expression
GXD Expression
Probe: MGI:3506614
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757721
Pattern: Single cells
Stage: TS21
Assay Id: MGI:3508092
Age: embryonic day 13.5
Image: 1
Note: Expression was detected in some cells.
Specimen Label: 1
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:5309692
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1757722
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5423037
Age: embryonic day 14.5
Image: MH212; Specimen C952
Specimen Label: MH212; Specimen C952
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:5309692
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1757522
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5423037
Age: embryonic day 14.5
Image: MH212; Specimen C952
Specimen Label: MH212; Specimen C952
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:3506614
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2850023
Stage: TS23
Assay Id: MGI:5539598
Age: embryonic day 15.5
Image: GUDMAP:5949
Specimen Label: GUDMAP:5949
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:3506614
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:2850023
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539598
Age: embryonic day 15.5
Image: GUDMAP:12687
Specimen Label: GUDMAP:12687
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:3506614
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:2850023
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539598
Age: embryonic day 15.5
Image: GUDMAP:12688
Specimen Label: GUDMAP:12688
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:5309692
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1738322
Stage: TS22
Assay Id: MGI:5423037
Age: embryonic day 14.5
Specimen Label: MH212; Specimen C952
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:5309692
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1802422
Stage: TS22
Assay Id: MGI:5423037
Age: embryonic day 14.5
Specimen Label: MH212; Specimen C952
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:3506614
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:1796223
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539598
Age: embryonic day 15.5
Image: GUDMAP:5949
Specimen Label: GUDMAP:5949
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:3506614
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:1796223
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539598
Age: embryonic day 15.5
Image: GUDMAP:12688
Specimen Label: GUDMAP:12688
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:5309692
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1768022
Stage: TS22
Assay Id: MGI:5423037
Age: embryonic day 14.5
Note: Expression was not detected in the skull (base and vault).
Specimen Label: MH212; Specimen C952
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:5309692
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:2672022
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5423037
Age: embryonic day 14.5
Image: MH212; Specimen C952
Note: Expression was detected in whisker follicle.
Specimen Label: MH212; Specimen C952
Detected: true
Specimen Num: 1
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Publication
23086935 | J:197117
First Author: Sun H
Year: 2012
Journal: J Biol Chem
Title: Poly-small ubiquitin-like modifier (PolySUMO)-binding proteins identified through a string search.
Volume: 287
Issue: 50
Pages: 42071-83
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Publication
11042109 | J:65663
 
First Author: Jolliffe CN
Year: 2000
Journal: Biochem J
Title: Identification of multiple proteins expressed in murine embryos as binding partners for the WW domains of the ubiquitin-protein ligase Nedd4.
Volume: 351 Pt 3
Pages: 557-65
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Publication
20711497 | J:163754
First Author: Dumitriu B
Year: 2010
Journal: PLoS One
Title: Sox6 is necessary for efficient erythropoiesis in adult mice under physiological and anemia-induced stress conditions.
Volume: 5
Issue: 8
Pages: e12088
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Publication
16601693 | J:109361
First Author: Liu W
Year: 2006
Journal: EMBO J
Title: Axin is a scaffold protein in TGF-beta signaling that promotes degradation of Smad7 by Arkadia.
Volume: 25
Issue: 8
Pages: 1646-58
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Publication
21574244 | J:174238
First Author: Rorick NK
Year: 2011
Journal: Am J Med Genet A
Title: Genomic strategy identifies a missense mutation in WD-repeat domain 65 (WDR65) in an individual with Van der Woude syndrome.
Volume: 155A
Issue: 6
Pages: 1314-21
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Publication
16919269 | J:112701
First Author: Bailey PJ
Year: 2006
Journal: Exp Cell Res
Title: A global genomic transcriptional code associated with CNS-expressed genes.
Volume: 312
Issue: 16
Pages: 3108-19
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Publication
20059953 | J:156017
First Author: Yokoyama S
Year: 2009
Journal: Dev Cell
Title: A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58.
Volume: 17
Issue: 6
Pages: 836-48
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Publication
15618518 | J:91257
First Author: Gray PA
Year: 2004
Journal: Science
Title: Mouse brain organization revealed through direct genome-scale TF expression analysis.
Volume: 306
Issue: 5705
Pages: 2255-7
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Publication
14681479 | J:122989
First Author: Visel A
Year: 2004
Journal: Nucleic Acids Res
Title: GenePaint.org: an atlas of gene expression patterns in the mouse embryo.
Volume: 32
Issue: Database issue
Pages: D552-6
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Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
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Publication
- | J:171409
     
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Interaction Experiment
Dalal NV (2012)
Description: RNF11 modulates microglia activation through NF-B signalling cascade.
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Publication
23222715 | -
First Author: Kostaras E
Year: 2013
Journal: Oncogene
Title: SARA and RNF11 interact with each other and ESCRT-0 core proteins and regulate degradative EGFR trafficking.
Volume: 32
Issue: 44
Pages: 5220-32
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Publication
14559117 | -
First Author: Kitching R
Year: 2003
Journal: Biochim Biophys Acta
Title: The RING-H2 protein RNF11 is differentially expressed in breast tumours and interacts with HECT-type E3 ligases.
Volume: 1639
Issue: 2
Pages: 104-12
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Publication
25195858 | -
First Author: Santonico E
Year: 2015
Journal: Oncogene
Title: RNF11 is a GGA protein cargo and acts as a molecular adaptor for GGA3 ubiquitination mediated by Itch.
Volume: 34
Issue: 26
Pages: 3377-90
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Publication
14562029 | -
First Author: Subramaniam V
Year: 2003
Journal: Br J Cancer
Title: The RING-H2 protein RNF11 is overexpressed in breast cancer and is a target of Smurf2 E3 ligase.
Volume: 89
Issue: 8
Pages: 1538-44
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Publication
19131965 | -
First Author: Shembade N
Year: 2009
Journal: EMBO J
Title: The ubiquitin-editing enzyme A20 requires RNF11 to downregulate NF-kappaB signalling.
Volume: 28
Issue: 5
Pages: 513-22
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Publication
14755250 | -
First Author: Li H
Year: 2004
Journal: Oncogene
Title: An RNF11: Smurf2 complex mediates ubiquitination of the AMSH protein.
Volume: 23
Issue: 10
Pages: 1801-8
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Publication
19262463 | -
First Author: Jacque E
Year: 2009
Journal: EMBO J
Title: RNF11, a new piece in the A20 puzzle.
Volume: 28
Issue: 5
Pages: 455-6
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Publication
19528490 | -
First Author: Azmi PB
Year: 2009
Journal: Anticancer Res
Title: The RING finger protein11 binds to Smad4 and enhances Smad4-dependant TGF-beta signalling.
Volume: 29
Issue: 6
Pages: 2253-63
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Protein Domain
IPR042981 | RNF11_RING-H2
Type: Domain
Description: RING finger protein 11 (RNF11) is an E3 ubiquitin-protein ligase that acts both as an adaptor and a modulator of itch-mediated control of ubiquitination events underlying membrane traffic. It is the downstream of an enzymatic cascade for the ubiquitination of specific substrates. It is also a molecular adaptor of homologous to E6-associated protein C terminus (HECT)-type ligases []. RNF11 has been implicated in the regulation of several signaling pathways. It enhances the transforming growth factor receptor (TGFR) signaling by both abrogating Smurf2-mediated receptor ubiquitination and by promoting the Smurf2-mediated degradation of AMSH (associated molecule with the SH3 domain of STAM), a de-ubiquitinating enzyme that enhances transforming growth factor-beta (TGF-beta) signalling and epidermal growth factor receptor (EGFR) endosomal recycling [, ]. It also acts directly on Smad4 to enhance Smad4 function, and plays a role in prolonged TGF-beta signalling []. Moreover, RNF11 functions as a critical component of the A20 ubiquitin-editing protein complex that negatively regulates tumor necrosis factor (TNF)-mediated nuclear factor (NF)-kappaB activation []. It also interacts with Smad anchor for receptor activation (SARA) and the endosomal sorting complex required for transport (ESCRT)-0 complex, thus participating in the regulation of lysosomal degradation of EGFR []. Furthermore, RNF11 acts as a novel GGA cargo actively participating in regulating the ubiquitination of the GGA protein family []. In addition, RNF11 functions together with TAX1BP1 to target TANK-binding kinase 1 (TBK1)/IkappaB kinase IKKi, and further restricts antiviral signaling and type I interferon (IFN)-beta production []. RNF11 contains an N-terminal PPPY motif that binds WW domain-containing proteins such as AIP4/itch, Nedd4 and Smurf1/2 (SMAD-specific E3 ubiquitin-protein ligase 1/2), and a C-terminal C3H2C3-type RING-H2 finger that functions as a scaffold for the coordinated transfer of ubiquitin to substrate proteins together with the E2 enzymes UbcH527 and Ubc13.
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Protein
Q9QYK7
Organism: Mus musculus/domesticus
Length: 154  
Fragment?: false
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Protein
Z4YLT8
Organism: Mus musculus/domesticus
Length: 144  
Fragment?: true
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