Ubiquinone (Q) functions as an electron carrier in the respiratory chain in mitochondria. Q biosynthesis involves a series of enzymatic steps, which are catalysed by the enzymes COQ1-COQ8 in Saccharomyces cerevisiae (Baker's yeast). COQ6, or ubiquinone biosynthesis monooxygenase, is a flavin-dependent enzyme localised to the matrix side of the inner mitochondrial membrane that is required for one or more steps in Q biosynthesis [, ].