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Search results 101 to 200 out of 385 for Pik3ca

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Category: Publication
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Type Details Score
Publication
22750293 | J:256569
First Author: Dubois E
Year: 2012
Journal: Cell Signal
Title: Developmental defects and rescue from glucose intolerance of a catalytically-inactive novel Ship2 mutant mouse.
Volume: 24
Issue: 11
Pages: 1971-80
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Publication
30076411 | J:269948
First Author: Stratikopoulos EE
Year: 2019
Journal: Oncogene
Title: Mouse ER+/PIK3CAH1047R breast cancers caused by exogenous estrogen are heterogeneously dependent on estrogen and undergo BIM-dependent apoptosis with BH3 and PI3K agents.
Volume: 38
Issue: 1
Pages: 47-59
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Publication
10196176 | J:54237
First Author: Bi L
Year: 1999
Journal: J Biol Chem
Title: Proliferative defect and embryonic lethality in mice homozygous for a deletion in the p110alpha subunit of phosphoinositide 3-kinase.
Volume: 274
Issue: 16
Pages: 10963-8
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Publication
15829307 | J:97985
First Author: Puente LG
Year: 2005
Journal: Mol Immunol
Title: Phosphatidylinositol-3-kinase regulates PKCtheta activity in cytotoxic T cells.
Volume: 42
Issue: 10
Pages: 1177-84
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Publication
21059846 | J:166673
First Author: Dou Z
Year: 2010
Journal: J Cell Biol
Title: The class IA phosphatidylinositol 3-kinase p110-beta subunit is a positive regulator of autophagy.
Volume: 191
Issue: 4
Pages: 827-43
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Publication
19604150 | J:155716
First Author: Tamura N
Year: 2009
Journal: Biochem J
Title: Specific role of phosphoinositide 3-kinase p110alpha in the regulation of phagocytosis and pinocytosis in macrophages.
Volume: 423
Issue: 1
Pages: 99-108
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Publication
23051731 | J:200258
First Author: Silió V
Year: 2012
Journal: Mol Biol Cell
Title: Phosphoinositide 3-kinase β regulates chromosome segregation in mitosis.
Volume: 23
Issue: 23
Pages: 4526-42
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Publication
27304846 | J:257615
First Author: Sellitto C
Year: 2016
Journal: Invest Ophthalmol Vis Sci
Title: The Phosphoinosotide 3-Kinase Catalytic Subunit p110α is Required for Normal Lens Growth.
Volume: 57
Issue: 7
Pages: 3145-51
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Publication
36078116 | J:329001
 
First Author: Sellitto C
Year: 2022
Journal: Cells
Title: Double Deletion of PI3K and PTEN Modifies Lens Postnatal Growth and Homeostasis.
Volume: 11
Issue: 17
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Publication
30590030 | J:270990
First Author: Murillo MM
Year: 2018
Journal: Cell Rep
Title: Disruption of the Interaction of RAS with PI 3-Kinase Induces Regression of EGFR-Mutant-Driven Lung Cancer.
Volume: 25
Issue: 13
Pages: 3545-3553.e2
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Publication
24691033 | J:213164
First Author: Nelson VL
Year: 2014
Journal: Am J Physiol Endocrinol Metab
Title: Adipose tissue insulin resistance due to loss of PI3K p110α leads to decreased energy expenditure and obesity.
Volume: 306
Issue: 10
Pages: E1205-16
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Publication
25269483 | J:218421
First Author: Beymer M
Year: 2014
Journal: Am J Physiol Endocrinol Metab
Title: Kisspeptin cell-specific PI3K signaling regulates hypothalamic kisspeptin expression and participates in the regulation of female fertility.
Volume: 307
Issue: 11
Pages: E969-82
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Publication
21464441 | J:171816
First Author: Chattopadhyay M
Year: 2011
Journal: Diabetes
Title: Ablation of PI3K p110-α prevents high-fat diet-induced liver steatosis.
Volume: 60
Issue: 5
Pages: 1483-92
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Publication
22802530 | J:185640
First Author: Utermark T
Year: 2012
Journal: Genes Dev
Title: The p110α and p110β isoforms of PI3K play divergent roles in mammary gland development and tumorigenesis.
Volume: 26
Issue: 14
Pages: 1573-86
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Publication
15713620 | J:96761
First Author: Brachmann SM
Year: 2005
Journal: Mol Cell Biol
Title: Phosphoinositide 3-kinase catalytic subunit deletion and regulatory subunit deletion have opposite effects on insulin sensitivity in mice.
Volume: 25
Issue: 5
Pages: 1596-607
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Publication
26880557 | J:231012
   
First Author: Westernberg L
Year: 2016
Journal: Elife
Title: Non-canonical antagonism of PI3K by the kinase Itpkb delays thymocyte β-selection and renders it Notch-dependent.
Volume: 5
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Publication
31120863 | J:336308
 
First Author: Hemmati S
Year: 2019
Journal: JCI Insight
Title: PI3 kinase alpha and delta promote hematopoietic stem cell activation.
Volume: 5
Issue: 13
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Publication
19883613 | J:155435
First Author: Al-Qassab H
Year: 2009
Journal: Cell Metab
Title: Dominant role of the p110beta isoform of PI3K over p110alpha in energy homeostasis regulation by POMC and AgRP neurons.
Volume: 10
Issue: 5
Pages: 343-54
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Publication
24043760 | J:204070
First Author: Soler A
Year: 2013
Journal: J Exp Med
Title: Inhibition of the p110α isoform of PI 3-kinase stimulates nonfunctional tumor angiogenesis.
Volume: 210
Issue: 10
Pages: 1937-45
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Publication
24569456 | J:209632
First Author: Gritsman K
Year: 2014
Journal: J Clin Invest
Title: Hematopoiesis and RAS-driven myeloid leukemia differentially require PI3K isoform p110α.
Volume: 124
Issue: 4
Pages: 1794-809
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Publication
29902570 | J:266612
First Author: Mujalli A
Year: 2018
Journal: Biochim Biophys Acta Mol Cell Biol Lipids
Title: Profiling of phosphoinositide molecular species in human and mouse platelets identifies new species increasing following stimulation.
Volume: 1863
Issue: 9
Pages: 1121-1131
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Publication
24229709 | J:206736
First Author: Castellano E
Year: 2013
Journal: Cancer Cell
Title: Requirement for interaction of PI3-kinase p110α with RAS in lung tumor maintenance.
Volume: 24
Issue: 5
Pages: 617-30
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Publication
30361695 | J:268748
First Author: Ying Z
Year: 2018
Journal: Nat Cell Biol
Title: Oncogenic activation of PI3K induces progenitor cell differentiation to suppress epidermal growth.
Volume: 20
Issue: 11
Pages: 1256-1266
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Publication
29449337 | J:285174
First Author: Alsina-Sanchís E
Year: 2018
Journal: Arterioscler Thromb Vasc Biol
Title: ALK1 Loss Results in Vascular Hyperplasia in Mice and Humans Through PI3K Activation.
Volume: 38
Issue: 5
Pages: 1216-1229
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Publication
22525701 | J:189325
First Author: Leystra AA
Year: 2012
Journal: Cancer Res
Title: Mice expressing activated PI3K rapidly develop advanced colon cancer.
Volume: 72
Issue: 12
Pages: 2931-6
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Publication
22824041 | J:188789
First Author: Yang KC
Year: 2012
Journal: J Mol Cell Cardiol
Title: Exercise training and PI3Kα-induced electrical remodeling is independent of cellular hypertrophy and Akt signaling.
Volume: 53
Issue: 4
Pages: 532-41
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Publication
29983910 | J:288803
 
First Author: Chaudhari A
Year: 2017
Journal: F1000Res
Title: Hepatic deletion of p110α and p85α results in insulin resistance despite sustained IRS1-associated phosphatidylinositol kinase activity.
Volume: 6
Pages: 1600
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Publication
30446640 | J:267756
First Author: Angulo-Urarte A
Year: 2018
Journal: Nat Commun
Title: Endothelial cell rearrangements during vascular patterning require PI3-kinase-mediated inhibition of actomyosin contractility.
Volume: 9
Issue: 1
Pages: 4826
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Publication
25589743 | J:217728
First Author: Tanida M
Year: 2015
Journal: J Neurosci
Title: Leptin receptor signaling in the hypothalamus regulates hepatic autonomic nerve activity via phosphatidylinositol 3-kinase and AMP-activated protein kinase.
Volume: 35
Issue: 2
Pages: 474-84
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Publication
31363081 | J:280932
First Author: Li ME
Year: 2019
Journal: Nat Commun
Title: Role of p110a subunit of PI3-kinase in skeletal muscle mitochondrial homeostasis and metabolism.
Volume: 10
Issue: 1
Pages: 3412
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Publication
11919689 | J:75617
First Author: Bi L
Year: 2002
Journal: Mamm Genome
Title: Early embryonic lethality in mice deficient in the p110beta catalytic subunit of PI 3-kinase.
Volume: 13
Issue: 3
Pages: 169-72
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Publication
18285463 | J:133923
First Author: Marqués M
Year: 2008
Journal: Mol Cell Biol
Title: Phosphoinositide 3-kinases p110alpha and p110beta regulate cell cycle entry, exhibiting distinct activation kinetics in G1 phase.
Volume: 28
Issue: 8
Pages: 2803-14
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Publication
24903091 | J:227104
First Author: Blair TA
Year: 2014
Journal: Arterioscler Thromb Vasc Biol
Title: Phosphoinositide 3-kinases p110α and p110β have differential roles in insulin-like growth factor-1-mediated Akt phosphorylation and platelet priming.
Volume: 34
Issue: 8
Pages: 1681-8
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Publication
15687236 | J:98972
First Author: Lelievre E
Year: 2005
Journal: Blood
Title: Deficiency in the p110alpha subunit of PI3K results in diminished Tie2 expression and Tie2(-/-)-like vascular defects in mice.
Volume: 105
Issue: 10
Pages: 3935-8
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Publication
26872540 | J:327397
First Author: Thomas DD
Year: 2016
Journal: Exp Hematol
Title: Insulin-like growth factor 2 modulates murine hematopoietic stem cell maintenance through upregulation of p57.
Volume: 44
Issue: 5
Pages: 422-433.e1
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Publication
19509054 | J:153176
First Author: Kingham E
Year: 2009
Journal: J Cell Sci
Title: Distinct roles for isoforms of the catalytic subunit of class-IA PI3K in the regulation of behaviour of murine embryonic stem cells.
Volume: 122
Issue: Pt 13
Pages: 2311-21
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Publication
19834495 | J:171800
First Author: Matheny RW Jr
Year: 2010
Journal: Cell Death Differ
Title: PI3K p110 alpha and p110 beta have differential effects on Akt activation and protection against oxidative stress-induced apoptosis in myoblasts.
Volume: 17
Issue: 4
Pages: 677-88
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Publication
28923937 | J:256919
First Author: Bosbach B
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Direct engagement of the PI3K pathway by mutant KIT dominates oncogenic signaling in gastrointestinal stromal tumor.
Volume: 114
Issue: 40
Pages: E8448-E8457
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Publication
29097657 | J:257063
First Author: Méndez-Pertuz M
Year: 2017
Journal: Nat Commun
Title: Modulation of telomere protection by the PI3K/AKT pathway.
Volume: 8
Issue: 1
Pages: 1278
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Publication
24991009 | J:317296
First Author: Utermark T
Year: 2014
Journal: J Virol
Title: The phosphatidylinositol 3-kinase (PI3K) isoform dependence of tumor formation is determined by the genetic mode of PI3K pathway activation rather than by tissue type.
Volume: 88
Issue: 18
Pages: 10673-9
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Publication
24131925 | J:316620
First Author: Wang Q
Year: 2013
Journal: Cell Cycle
Title: The gene dosage of class Ia PI3K dictates the development of PTEN hamartoma tumor syndrome.
Volume: 12
Issue: 23
Pages: 3589-93
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Publication
9235916 | J:42042
First Author: Chantry D
Year: 1997
Journal: J Biol Chem
Title: p110delta, a novel phosphatidylinositol 3-kinase catalytic subunit that associates with p85 and is expressed predominantly in leukocytes.
Volume: 272
Issue: 31
Pages: 19236-41
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Publication
15496927 | J:93235
First Author: Ali K
Year: 2004
Journal: Nature
Title: Essential role for the p110delta phosphoinositide 3-kinase in the allergic response.
Volume: 431
Issue: 7011
Pages: 1007-11
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Publication
17540175 | J:122866
First Author: Gupta S
Year: 2007
Journal: Cell
Title: Binding of ras to phosphoinositide 3-kinase p110alpha is required for ras-driven tumorigenesis in mice.
Volume: 129
Issue: 5
Pages: 957-68
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Publication
18594509 | J:138565
First Author: Jia S
Year: 2008
Journal: Nature
Title: Essential roles of PI(3)K-p110beta in cell growth, metabolism and tumorigenesis.
Volume: 454
Issue: 7205
Pages: 776-9
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Publication
27402769 | J:235157
First Author: Juvekar A
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Phosphoinositide 3-kinase inhibitors induce DNA damage through nucleoside depletion.
Volume: 113
Issue: 30
Pages: E4338-47
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Publication
22806988 | J:233267
First Author: Shinohara M
Year: 2012
Journal: J Bone Miner Res
Title: Class IA phosphatidylinositol 3-kinase regulates osteoclastic bone resorption through protein kinase B-mediated vesicle transport.
Volume: 27
Issue: 12
Pages: 2464-75
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Publication
35013322 | J:330403
First Author: Qi Z
Year: 2022
Journal: Nat Commun
Title: Overcoming resistance to immune checkpoint therapy in PTEN-null prostate cancer by intermittent anti-PI3Kα/β/δ treatment.
Volume: 13
Issue: 1
Pages: 182
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23258246 | J:194362
First Author: Jia S
Year: 2013
Journal: Cancer Discov
Title: Opposing effects of androgen deprivation and targeted therapy on prostate cancer prevention.
Volume: 3
Issue: 1
Pages: 44-51
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24553178 | J:210890
First Author: Goodwin CB
Year: 2014
Journal: Blood
Title: PI3K p110δ uniquely promotes gain-of-function Shp2-induced GM-CSF hypersensitivity in a model of JMML.
Volume: 123
Issue: 18
Pages: 2838-42
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22722829 | J:186709
First Author: Robinson G
Year: 2012
Journal: Nature
Title: Novel mutations target distinct subgroups of medulloblastoma.
Volume: 488
Issue: 7409
Pages: 43-8
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Publication
26896753 | J:315713
First Author: Gámez B
Year: 2016
Journal: J Bone Miner Res
Title: Class I PI-3-Kinase Signaling Is Critical for Bone Formation Through Regulation of SMAD1 Activity in Osteoblasts.
Volume: 31
Issue: 8
Pages: 1617-30
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Publication
19597047 | J:166421
First Author: Lu Z
Year: 2009
Journal: Circulation
Title: Loss of cardiac phosphoinositide 3-kinase p110 alpha results in contractile dysfunction.
Volume: 120
Issue: 4
Pages: 318-25
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22539774 | J:183985
First Author: Lu Z
Year: 2012
Journal: Sci Transl Med
Title: Suppression of phosphoinositide 3-kinase signaling and alteration of multiple ion currents in drug-induced long QT syndrome.
Volume: 4
Issue: 131
Pages: 131ra50
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Publication
21912691 | J:177701
First Author: Wu CY
Year: 2011
Journal: PLoS One
Title: PI3Ks maintain the structural integrity of T-tubules in cardiac myocytes.
Volume: 6
Issue: 9
Pages: e24404
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Publication
28783168 | J:247760
First Author: Simond AM
Year: 2017
Journal: Oncogene
Title: ErbB2-positive mammary tumors can escape PI3K-p110α loss through downregulation of the Pten tumor suppressor.
Volume: 36
Issue: 43
Pages: 6059-6066
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Publication
23873941 | J:199362
First Author: Wang Q
Year: 2013
Journal: Genes Dev
Title: Spatially distinct roles of class Ia PI3K isoforms in the development and maintenance of PTEN hamartoma tumor syndrome.
Volume: 27
Issue: 14
Pages: 1568-80
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Publication
26058079 | J:222915
First Author: Stratikopoulos EE
Year: 2015
Journal: Cancer Cell
Title: Kinase and BET Inhibitors Together Clamp Inhibition of PI3K Signaling and Overcome Resistance to Therapy.
Volume: 27
Issue: 6
Pages: 837-51
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23029326 | J:191970
First Author: Juss JK
Year: 2012
Journal: PLoS One
Title: Functional redundancy of class I phosphoinositide 3-kinase (PI3K) isoforms in signaling growth factor-mediated human neutrophil survival.
Volume: 7
Issue: 9
Pages: e45933
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Publication
36812307 | J:336309
First Author: Ames K
Year: 2023
Journal: Sci Adv
Title: PI3-kinase deletion promotes myelodysplasia by dysregulating autophagy in hematopoietic stem cells.
Volume: 9
Issue: 8
Pages: eade8222
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Publication
33065020 | J:297231
First Author: Yip HYK
Year: 2020
Journal: Mol Cell
Title: Control of Glucocorticoid Receptor Levels by PTEN Establishes a Failsafe Mechanism for Tumor Suppression.
Volume: 80
Issue: 2
Pages: 279-295.e8
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Publication
25472943 | J:221978
First Author: Deuker MM
Year: 2015
Journal: Cancer Discov
Title: PI3'-kinase inhibition forestalls the onset of MEK1/2 inhibitor resistance in BRAF-mutated melanoma.
Volume: 5
Issue: 2
Pages: 143-53
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Publication
32414808 | J:291916
First Author: Stark AK
Year: 2020
Journal: J Immunol
Title: Loss of Phosphatidylinositol 3-Kinase Activity in Regulatory T Cells Leads to Neuronal Inflammation.
Volume: 205
Issue: 1
Pages: 78-89
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Publication
23023391 | J:188561
First Author: Aksoy E
Year: 2012
Journal: Nat Immunol
Title: The p110δ isoform of the kinase PI(3)K controls the subcellular compartmentalization of TLR4 signaling and protects from endotoxic shock.
Volume: 13
Issue: 11
Pages: 1045-1054
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Publication
20534549 | J:161378
First Author: Foukas LC
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Activity of any class IA PI3K isoform can sustain cell proliferation and survival.
Volume: 107
Issue: 25
Pages: 11381-6
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Publication
33159421 | J:301545
   
First Author: Iacono A
Year: 2020
Journal: EMBO Rep
Title: Class IA PI3Ks regulate subcellular and functional dynamics of IDO1.
Pages: e49756
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23541372 | J:299563
First Author: Harlan SM
Year: 2013
Journal: Cell Metab
Title: Hypothalamic mTORC1 signaling controls sympathetic nerve activity and arterial pressure and mediates leptin effects.
Volume: 17
Issue: 4
Pages: 599-606
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25452273 | J:217379
First Author: Baer R
Year: 2014
Journal: Genes Dev
Title: Pancreatic cell plasticity and cancer initiation induced by oncogenic Kras is completely dependent on wild-type PI 3-kinase p110α.
Volume: 28
Issue: 23
Pages: 2621-35
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Publication
31452510 | J:278997
   
First Author: van Veen JE
Year: 2019
Journal: Elife
Title: Mutationally-activated PI3'-kinase-α promotes de-differentiation of lung tumors initiated by the BRAFV600E oncoprotein kinase.
Volume: 8
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Publication
25398937 | J:221208
First Author: Laurent PA
Year: 2015
Journal: Blood
Title: Platelet PI3Kβ and GSK3 regulate thrombus stability at a high shear rate.
Volume: 125
Issue: 5
Pages: 881-8
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Publication
27071537 | J:236891
 
First Author: Castellano E
Year: 2016
Journal: Nat Commun
Title: RAS signalling through PI3-Kinase controls cell migration via modulation of Reelin expression.
Volume: 7
Pages: 11245
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Publication
21246652 | J:167836
First Author: San Miguel S
Year: 2011
Journal: Dev Dyn
Title: Ephrin reverse signaling controls palate fusion via a PI3 kinase-dependent mechanism.
Volume: 240
Issue: 2
Pages: 357-64
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25618408 | J:232675
First Author: McLean BA
Year: 2015
Journal: Cardiovasc Res
Title: PI3Kα is essential for the recovery from Cre/tamoxifen cardiotoxicity and in myocardial insulin signalling but is not required for normal myocardial contractility in the adult heart.
Volume: 105
Issue: 3
Pages: 292-303
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19819947 | J:158221
First Author: Hill JW
Year: 2009
Journal: Endocrinology
Title: Phosphatidyl inositol 3-kinase signaling in hypothalamic proopiomelanocortin neurons contributes to the regulation of glucose homeostasis.
Volume: 150
Issue: 11
Pages: 4874-82
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27965101 | J:241714
First Author: Matheny RW Jr
Year: 2017
Journal: Biochem Biophys Res Commun
Title: Skeletal muscle PI3K p110β regulates expression of AMP-activated protein kinase.
Volume: 482
Issue: 4
Pages: 1420-1426
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7534285 | J:23762
First Author: Drachman JG
Year: 1995
Journal: J Biol Chem
Title: The c-Mpl ligand (thrombopoietin) stimulates tyrosine phosphorylation of Jak2, Shc, and c-Mpl.
Volume: 270
Issue: 10
Pages: 4979-82
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17908814 | J:127648
First Author: Lee CW
Year: 2007
Journal: Infect Immun
Title: Phosphoinositide-3-kinase-dependent, MyD88-independent induction of CC-type chemokines characterizes the macrophage response to Toxoplasma gondii strains with high virulence.
Volume: 75
Issue: 12
Pages: 5788-97
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17596516 | J:128307
First Author: Kazemi S
Year: 2007
Journal: Mol Biol Cell
Title: A novel function of eIF2alpha kinases as inducers of the phosphoinositide-3 kinase signaling pathway.
Volume: 18
Issue: 9
Pages: 3635-44
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18187452 | J:131082
First Author: Heit B
Year: 2008
Journal: J Cell Sci
Title: PI3K accelerates, but is not required for, neutrophil chemotaxis to fMLP.
Volume: 121
Issue: Pt 2
Pages: 205-14
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19033389 | J:146084
First Author: Papakonstanti EA
Year: 2008
Journal: J Cell Sci
Title: Distinct roles of class IA PI3K isoforms in primary and immortalised macrophages.
Volume: 121
Issue: Pt 24
Pages: 4124-33
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19126672 | J:146196
First Author: Weiger MC
Year: 2009
Journal: J Cell Sci
Title: Spontaneous phosphoinositide 3-kinase signaling dynamics drive spreading and random migration of fibroblasts.
Volume: 122
Issue: Pt 3
Pages: 313-23
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17579043 | J:149418
First Author: Polumuri SK
Year: 2007
Journal: J Immunol
Title: Role of phosphatidylinositol-3 kinase in transcriptional regulation of TLR-induced IL-12 and IL-10 by Fc gamma receptor ligation in murine macrophages.
Volume: 179
Issue: 1
Pages: 236-46
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19505983 | J:176792
First Author: Zhang QJ
Year: 2009
Journal: J Physiol
Title: Endothelial nitric oxide synthase phosphorylation in treadmill-running mice: role of vascular signalling kinases.
Volume: 587
Issue: Pt 15
Pages: 3911-20
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Publication
37606694 | J:343708
First Author: Wang H
Year: 2023
Journal: Mol Cancer Res
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