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Search results 101 to 200 out of 301 for Prkn

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Category: Publication
Type Details Score
Publication
First Author: Edmunds LR
Year: 2019
Journal: Physiol Rep
Title: Hepatic insulin sensitivity is improved in high-fat diet-fed Park2 knockout mice in association with increased hepatic AMPK activation and reduced steatosis.
Volume: 7
Issue: 21
Pages: e14281
Publication
First Author: Ramesh M
Year: 2019
Journal: FASEB J
Title: Mitophagy protects against statin-mediated skeletal muscle toxicity.
Volume: 33
Issue: 11
Pages: 11857-11869
Publication  
First Author: Torii S
Year: 2020
Journal: Int J Mol Sci
Title: Mitochondrial E3 Ubiquitin Ligase Parkin: Relationships with Other Causal Proteins in Familial Parkinson's Disease and Its Substrate-Involved Mouse Experimental Models.
Volume: 21
Issue: 4
Publication    
First Author: Shimizu N
Year: 1999
Journal: GenBank Submission
Title: Mus musculus mRNA for parkin, complete cds
Pages: AB019558
Publication
First Author: Kageyama Y
Year: 2012
Journal: J Cell Biol
Title: Mitochondrial division ensures the survival of postmitotic neurons by suppressing oxidative damage.
Volume: 197
Issue: 4
Pages: 535-51
Publication
First Author: Van Humbeeck C
Year: 2011
Journal: J Neurosci
Title: Parkin interacts with Ambra1 to induce mitophagy.
Volume: 31
Issue: 28
Pages: 10249-61
Publication
First Author: Um JW
Year: 2006
Journal: J Biol Chem
Title: Parkin ubiquitinates and promotes the degradation of RanBP2.
Volume: 281
Issue: 6
Pages: 3595-603
Publication
First Author: Wang C
Year: 2018
Journal: Nat Commun
Title: Synaptotagmin-11 is a critical mediator of parkin-linked neurotoxicity and Parkinson's disease-like pathology.
Volume: 9
Issue: 1
Pages: 81
Publication
First Author: Kageyama Y
Year: 2014
Journal: EMBO J
Title: Parkin-independent mitophagy requires Drp1 and maintains the integrity of mammalian heart and brain.
Volume: 33
Issue: 23
Pages: 2798-813
Publication
First Author: Ko HS
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Phosphorylation by the c-Abl protein tyrosine kinase inhibits parkin's ubiquitination and protective function.
Volume: 107
Issue: 38
Pages: 16691-6
Publication    
First Author: Hoffmann-Conaway S
Year: 2020
Journal: Elife
Title: Parkin contributes to synaptic vesicle autophagy in Bassoon-deficient mice.
Volume: 9
Publication
First Author: Gunn TM
Year: 2019
Journal: Mamm Genome
Title: Chronic and age-dependent effects of the spongiform neurodegeneration-associated MGRN1 E3 ubiquitin ligase on mitochondrial homeostasis.
Volume: 30
Issue: 5-6
Pages: 151-165
Publication
First Author: Yu YR
Year: 2020
Journal: Nat Immunol
Title: Disturbed mitochondrial dynamics in CD8+ TILs reinforce T cell exhaustion.
Volume: 21
Issue: 12
Pages: 1540-1551
Publication
First Author: He J
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: PICK1 inhibits the E3 ubiquitin ligase activity of Parkin and reduces its neuronal protective effect.
Volume: 115
Issue: 30
Pages: E7193-E7201
Publication
First Author: Sarraf SA
Year: 2019
Journal: Cell Rep
Title: PINK1/Parkin Influences Cell Cycle by Sequestering TBK1 at Damaged Mitochondria, Inhibiting Mitosis.
Volume: 29
Issue: 1
Pages: 225-235.e5
Publication  
First Author: Lu X
Year: 2018
Journal: Sci Signal
Title: Mitophagy controls beige adipocyte maintenance through a Parkin-dependent and UCP1-independent mechanism.
Volume: 11
Issue: 527
Publication
First Author: Berthet A
Year: 2012
Journal: J Neurosci
Title: L-DOPA impairs proteasome activity in parkinsonism through D1 dopamine receptor.
Volume: 32
Issue: 2
Pages: 681-91
Publication
First Author: Kurtenbach S
Year: 2013
Journal: PLoS One
Title: Olfaction in three genetic and two MPTP-induced Parkinson's disease mouse models.
Volume: 8
Issue: 10
Pages: e77509
Publication    
First Author: Woodall BP
Year: 2019
Journal: JCI Insight
Title: Parkin does not prevent accelerated cardiac aging in mitochondrial DNA mutator mice.
Volume: 5
Publication
First Author: Corsa CAS
Year: 2019
Journal: J Biol Chem
Title: The E3 ubiquitin ligase parkin is dispensable for metabolic homeostasis in murine pancreatic β cells and adipocytes.
Volume: 294
Issue: 18
Pages: 7296-7307
Publication
First Author: de Pablo-Latorre R
Year: 2012
Journal: Hum Mol Genet
Title: Impaired parkin-mediated mitochondrial targeting to autophagosomes differentially contributes to tissue pathology in lysosomal storage diseases.
Volume: 21
Issue: 8
Pages: 1770-81
Publication
First Author: Paul S
Year: 2021
Journal: Biochim Biophys Acta Gen Subj
Title: Hidden phenotypes of PINK1/Parkin knockout mice.
Volume: 1865
Issue: 6
Pages: 129871
Publication
First Author: Duan K
Year: 2021
Journal: Neuron
Title: Mitophagy in the basolateral amygdala mediates increased anxiety induced by aversive social experience.
Volume: 109
Issue: 23
Pages: 3793-3809.e8
Publication  
First Author: Cremer JN
Year: 2015
Journal: Neuroscience
Title: Changes in the expression of neurotransmitter receptors in Parkin and DJ-1 knockout mice--A quantitative multireceptor study.
Volume: 311
Pages: 539-51
Publication
First Author: Tong M
Year: 2019
Journal: Circ Res
Title: Mitophagy Is Essential for Maintaining Cardiac Function During High Fat Diet-Induced Diabetic Cardiomyopathy.
Volume: 124
Issue: 9
Pages: 1360-1371
Publication
First Author: Sul JW
Year: 2013
Journal: Hum Mol Genet
Title: Accumulation of the parkin substrate, FAF1, plays a key role in the dopaminergic neurodegeneration.
Volume: 22
Issue: 8
Pages: 1558-73
Publication
First Author: Hollville E
Year: 2020
Journal: Sci Rep
Title: Characterization of a Cul9-Parkin double knockout mouse model for Parkinson's disease.
Volume: 10
Issue: 1
Pages: 16886
Publication
First Author: Martella G
Year: 2009
Journal: Exp Neurol
Title: Enhanced sensitivity to group II mGlu receptor activation at corticostriatal synapses in mice lacking the familial parkinsonism-linked genes PINK1 or Parkin.
Volume: 215
Issue: 2
Pages: 388-96
Publication
First Author: Mizumura K
Year: 2014
Journal: J Clin Invest
Title: Mitophagy-dependent necroptosis contributes to the pathogenesis of COPD.
Volume: 124
Issue: 9
Pages: 3987-4003
Publication
First Author: Ashrafi G
Year: 2014
Journal: J Cell Biol
Title: Mitophagy of damaged mitochondria occurs locally in distal neuronal axons and requires PINK1 and Parkin.
Volume: 206
Issue: 5
Pages: 655-70
Publication
First Author: Matheoud D
Year: 2016
Journal: Cell
Title: Parkinson's Disease-Related Proteins PINK1 and Parkin Repress Mitochondrial Antigen Presentation.
Volume: 166
Issue: 2
Pages: 314-327
Publication
First Author: Li J
Year: 2020
Journal: Biochem Biophys Res Commun
Title: Mitochondrial DNA heteroplasmy rises in substantial nigra of aged PINK1 KO mice.
Volume: 521
Issue: 4
Pages: 1024-1029
Publication  
First Author: Rogers RS
Year: 2017
Journal: Front Neurosci
Title: Impaired Mitophagy Plays a Role in Denervation of Neuromuscular Junctions in ALS Mice.
Volume: 11
Pages: 473
Publication  
First Author: Hwang CJ
Year: 2017
Journal: Redox Biol
Title: Parkin deficiency exacerbate ethanol-induced dopaminergic neurodegeneration by P38 pathway dependent inhibition of autophagy and mitochondrial function.
Volume: 11
Pages: 456-468
Publication
First Author: Yuan Y
Year: 2017
Journal: Autophagy
Title: BNIP3L/NIX-mediated mitophagy protects against ischemic brain injury independent of PARK2.
Volume: 13
Issue: 10
Pages: 1754-1766
Publication  
First Author: Smith CA
Year: 2019
Journal: JCI Insight
Title: Macrophage migration inhibitory factor enhances influenza-associated mortality in mice.
Volume: 4
Issue: 13
Publication
First Author: Kubli DA
Year: 2015
Journal: PLoS One
Title: PINK1 Is Dispensable for Mitochondrial Recruitment of Parkin and Activation of Mitophagy in Cardiac Myocytes.
Volume: 10
Issue: 6
Pages: e0130707
Publication  
First Author: Kabayama H
Year: 2017
Journal: Mol Cell Neurosci
Title: Parkin promotes proteasomal degradation of synaptotagmin IV by accelerating polyubiquitination.
Volume: 80
Pages: 89-99
Publication  
First Author: Li S
Year: 2020
Journal: Free Radic Biol Med
Title: Drp1-regulated PARK2-dependent mitophagy protects against renal fibrosis in unilateral ureteral obstruction.
Volume: 152
Pages: 632-649
Publication  
First Author: Ekholm-Reed S
Year: 2019
Journal: Commun Biol
Title: Reducing Mcl-1 gene dosage induces dopaminergic neuronal loss and motor impairments in Park2 knockout mice.
Volume: 2
Pages: 125
Publication
First Author: Zhang Y
Year: 2021
Journal: Am J Physiol Lung Cell Mol Physiol
Title: PINK1 mediates the protective effects of thyroid hormone T3 in hyperoxia-induced lung injury.
Volume: 320
Issue: 6
Pages: L1118-L1125
Publication
First Author: Yoshida T
Year: 2010
Journal: Biochem Biophys Res Commun
Title: Neurodegeneration in mnd2 mutant mice is not prevented by parkin transgene.
Volume: 402
Issue: 4
Pages: 676-9
Publication
First Author: Mouton-Liger F
Year: 2018
Journal: Glia
Title: Parkin deficiency modulates NLRP3 inflammasome activation by attenuating an A20-dependent negative feedback loop.
Volume: 66
Issue: 8
Pages: 1736-1751
Publication  
First Author: Ageta-Ishihara N
Year: 2013
Journal: Mol Brain
Title: Chronic overload of SEPT4, a parkin substrate that aggregates in Parkinson's disease, causes behavioral alterations but not neurodegeneration in mice.
Volume: 6
Pages: 35
Publication
First Author: Klinkenberg M
Year: 2012
Journal: Neurogenetics
Title: Restriction of trophic factors and nutrients induces PARKIN expression.
Volume: 13
Issue: 1
Pages: 9-21
Publication
First Author: Soh JEC
Year: 2023
Journal: J Biol Chem
Title: RhoA rescues cardiac senescence by regulating Parkin-mediated mitophagy.
Volume: 299
Issue: 3
Pages: 102993
Publication
First Author: Navarro P
Year: 2008
Journal: Behav Brain Res
Title: Memory and exploratory impairment in mice that lack the Park-2 gene and that over-express the human FTDP-17 mutant Tau.
Volume: 189
Issue: 2
Pages: 350-6
Publication
First Author: Gautier CA
Year: 2016
Journal: Hum Mol Genet
Title: The endoplasmic reticulum-mitochondria interface is perturbed in PARK2 knockout mice and patients with PARK2 mutations.
Volume: 25
Issue: 14
Pages: 2972-2984
Publication
First Author: Rodríguez-Navarro JA
Year: 2008
Journal: J Neurochem
Title: Gender differences and estrogen effects in parkin null mice.
Volume: 106
Issue: 5
Pages: 2143-57
Publication
First Author: Um JW
Year: 2009
Journal: Mol Cell Neurosci
Title: Molecular interaction between parkin and PINK1 in mammalian neuronal cells.
Volume: 40
Issue: 4
Pages: 421-32
Publication
First Author: Imai Y
Year: 2003
Journal: J Biol Chem
Title: A product of the human gene adjacent to parkin is a component of Lewy bodies and suppresses Pael receptor-induced cell death.
Volume: 278
Issue: 51
Pages: 51901-10
Publication
First Author: Rawal N
Year: 2009
Journal: Biochem Biophys Res Commun
Title: Parkin protects dopaminergic neurons from excessive Wnt/beta-catenin signaling.
Volume: 388
Issue: 3
Pages: 473-8
Publication
First Author: Van Humbeeck C
Year: 2008
Journal: Eur J Neurosci
Title: Parkin occurs in a stable, non-covalent, approximately 110-kDa complex in brain.
Volume: 27
Issue: 2
Pages: 284-93
Publication
First Author: Son JH
Year: 2005
Journal: J Neurochem
Title: Neurotoxicity and behavioral deficits associated with Septin 5 accumulation in dopaminergic neurons.
Volume: 94
Issue: 4
Pages: 1040-53
Publication  
First Author: Brody KM
Year: 2008
Journal: Brain Res
Title: Regional and cellular localisation of Parkin co-regulated gene in developing and adult mouse brain.
Volume: 1201
Pages: 177-86
Publication
First Author: Park HM
Year: 2009
Journal: Biochem Biophys Res Commun
Title: The serine protease HtrA2/Omi cleaves Parkin and irreversibly inactivates its E3 ubiquitin ligase activity.
Volume: 387
Issue: 3
Pages: 537-42
Publication
First Author: Durcan TM
Year: 2011
Journal: Hum Mol Genet
Title: The Machado-Joseph disease-associated mutant form of ataxin-3 regulates parkin ubiquitination and stability.
Volume: 20
Issue: 1
Pages: 141-54
Publication  
First Author: Li Y
Year: 2011
Journal: Neuroscience
Title: p32 regulates mitochondrial morphology and dynamics through parkin.
Volume: 199
Pages: 346-58
Publication
First Author: Matsui H
Year: 2013
Journal: Hum Mol Genet
Title: PINK1 and Parkin complementarily protect dopaminergic neurons in vertebrates.
Volume: 22
Issue: 12
Pages: 2423-34
Publication
First Author: Koyano F
Year: 2013
Journal: Genes Cells
Title: The principal PINK1 and Parkin cellular events triggered in response to dissipation of mitochondrial membrane potential occur in primary neurons.
Volume: 18
Issue: 8
Pages: 672-81
Publication
First Author: Durcan TM
Year: 2014
Journal: EMBO J
Title: USP8 regulates mitophagy by removing K6-linked ubiquitin conjugates from parkin.
Volume: 33
Issue: 21
Pages: 2473-91
Publication
First Author: Roy M
Year: 2016
Journal: Biochem Biophys Res Commun
Title: Parkin suppresses Drp1-independent mitochondrial division.
Volume: 475
Issue: 3
Pages: 283-8
Publication
First Author: Stephenson SEM
Year: 2018
Journal: Sci Rep
Title: Generation and characterisation of a parkin-Pacrg knockout mouse line and a Pacrg knockout mouse line.
Volume: 8
Issue: 1
Pages: 7528
Publication
First Author: Manzella N
Year: 2018
Journal: Aging Cell
Title: Monoamine oxidase-A is a novel driver of stress-induced premature senescence through inhibition of parkin-mediated mitophagy.
Volume: 17
Issue: 5
Pages: e12811
Publication  
First Author: Lee YS
Year: 2018
Journal: Cancer Lett
Title: Deficiency of parkin suppresses melanoma tumor development and metastasis through inhibition of MFN2 ubiquitination.
Volume: 433
Pages: 156-164
Publication  
First Author: Wang Y
Year: 2020
Journal: Neurosci Lett
Title: Parkin-dependent and -independent degradation of synaptotagmin-11 in neurons and astrocytes.
Volume: 739
Pages: 135402
Publication  
First Author: Zhang J
Year: 2021
Journal: Free Radic Biol Med
Title: PINK1/PARK2 dependent mitophagy effectively suppresses NLRP3 inflammasome to alleviate acute pancreatitis.
Volume: 166
Pages: 147-164
Publication
First Author: Furuya N
Year: 2014
Journal: Autophagy
Title: PARK2/Parkin-mediated mitochondrial clearance contributes to proteasome activation during slow-twitch muscle atrophy via NFE2L1 nuclear translocation.
Volume: 10
Issue: 4
Pages: 631-41
Publication
First Author: Lorenzetti D
Year: 2004
Journal: Mamm Genome
Title: The neurological mutant quaking(viable) is Parkin deficient.
Volume: 15
Issue: 3
Pages: 210-7
Publication
First Author: Hofmeister-Brix A
Year: 2013
Journal: J Biol Chem
Title: Identification of the ubiquitin-like domain of midnolin as a new glucokinase interaction partner.
Volume: 288
Issue: 50
Pages: 35824-39
Publication
First Author: Shin JH
Year: 2011
Journal: Cell
Title: PARIS (ZNF746) repression of PGC-1α contributes to neurodegeneration in Parkinson's disease.
Volume: 144
Issue: 5
Pages: 689-702
Publication  
First Author: Algarzae N
Year: 2012
Journal: Neuroscience
Title: Parkin prevents cortical atrophy and Aβ-induced alterations of brain metabolism: ¹³C NMR and magnetic resonance imaging studies in AD models.
Volume: 225
Pages: 22-34
Publication
First Author: Shao D
Year: 2020
Journal: Circulation
Title: Increasing Fatty Acid Oxidation Prevents High-Fat Diet-Induced Cardiomyopathy Through Regulating Parkin-Mediated Mitophagy.
Volume: 142
Issue: 10
Pages: 983-997
Publication
First Author: Matsuzawa-Ishimoto Y
Year: 2017
Journal: J Exp Med
Title: Autophagy protein ATG16L1 prevents necroptosis in the intestinal epithelium.
Volume: 214
Issue: 12
Pages: 3687-3705
Publication  
First Author: Jo A
Year: 2021
Journal: Sci Transl Med
Title: PARIS farnesylation prevents neurodegeneration in models of Parkinson's disease.
Volume: 13
Issue: 604
Publication
First Author: Pickrell AM
Year: 2015
Journal: Neuron
Title: Endogenous Parkin Preserves Dopaminergic Substantia Nigral Neurons following Mitochondrial DNA Mutagenic Stress.
Volume: 87
Issue: 2
Pages: 371-81
Publication
First Author: Fournier M
Year: 2009
Journal: PLoS One
Title: Parkin deficiency delays motor decline and disease manifestation in a mouse model of synucleinopathy.
Volume: 4
Issue: 8
Pages: e6629
Publication
First Author: Huang YF
Year: 2020
Journal: FASEB J
Title: The protective effort of GPCR kinase 2-interacting protein-1 in neurons via promoting Beclin1-Parkin induced mitophagy at the early stage of spinal cord ischemia-reperfusion injury.
Volume: 34
Issue: 2
Pages: 2055-2074
Publication
First Author: Kitao Y
Year: 2007
Journal: Hum Mol Genet
Title: Pael receptor induces death of dopaminergic neurons in the substantia nigra via endoplasmic reticulum stress and dopamine toxicity, which is enhanced under condition of parkin inactivation.
Volume: 16
Issue: 1
Pages: 50-60
Publication
First Author: Halbach MV
Year: 2015
Journal: PLoS One
Title: Both ubiquitin ligases FBXW8 and PARK2 are sequestrated into insolubility by ATXN2 PolyQ expansions, but only FBXW8 expression is dysregulated.
Volume: 10
Issue: 3
Pages: e0121089
Publication
First Author: von Coelln R
Year: 2006
Journal: J Neurosci
Title: Inclusion body formation and neurodegeneration are parkin independent in a mouse model of alpha-synucleinopathy.
Volume: 26
Issue: 14
Pages: 3685-96
Publication
First Author: Essandoh K
Year: 2019
Journal: J Biol Chem
Title: Tumor susceptibility gene 101 ameliorates endotoxin-induced cardiac dysfunction by enhancing Parkin-mediated mitophagy.
Volume: 294
Issue: 48
Pages: 18057-18068
Publication
First Author: Hong X
Year: 2014
Journal: Hum Mol Genet
Title: Parkin overexpression ameliorates hippocampal long-term potentiation and β-amyloid load in an Alzheimer's disease mouse model.
Volume: 23
Issue: 4
Pages: 1056-72
Publication
First Author: Lee Y
Year: 2011
Journal: Am J Physiol Heart Circ Physiol
Title: Mitochondrial autophagy by Bnip3 involves Drp1-mediated mitochondrial fission and recruitment of Parkin in cardiac myocytes.
Volume: 301
Issue: 5
Pages: H1924-31
Publication
First Author: Lin MY
Year: 2017
Journal: Neuron
Title: Releasing Syntaphilin Removes Stressed Mitochondria from Axons Independent of Mitophagy under Pathophysiological Conditions.
Volume: 94
Issue: 3
Pages: 595-610.e6
Publication
First Author: Rosen KM
Year: 2006
Journal: J Biol Chem
Title: Parkin protects against mitochondrial toxins and beta-amyloid accumulation in skeletal muscle cells.
Volume: 281
Issue: 18
Pages: 12809-16
Publication
First Author: Park KR
Year: 2019
Journal: PLoS One
Title: Loss of parkin reduces lung tumor development by blocking p21 degradation.
Volume: 14
Issue: 5
Pages: e0217037
Publication  
First Author: Khang R
Year: 2015
Journal: Neuroscience
Title: Dysregulation of parkin in the substantia nigra of db/db and high-fat diet mice.
Volume: 294
Pages: 182-92
Publication  
First Author: Maraschi A
Year: 2014
Journal: Nat Commun
Title: Parkin regulates kainate receptors by interacting with the GluK2 subunit.
Volume: 5
Pages: 5182
Publication
First Author: Poulogiannis G
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: PARK2 deletions occur frequently in sporadic colorectal cancer and accelerate adenoma development in Apc mutant mice.
Volume: 107
Issue: 34
Pages: 15145-50
Publication
First Author: Bouman L
Year: 2011
Journal: Cell Death Differ
Title: Parkin is transcriptionally regulated by ATF4: evidence for an interconnection between mitochondrial stress and ER stress.
Volume: 18
Issue: 5
Pages: 769-82
Publication  
First Author: Baaske MK
Year: 2020
Journal: Neurobiol Dis
Title: Parkin deficiency perturbs striatal circuit dynamics.
Volume: 137
Pages: 104737
Publication
First Author: Sato S
Year: 2006
Journal: EMBO J
Title: 14-3-3eta is a novel regulator of parkin ubiquitin ligase.
Volume: 25
Issue: 1
Pages: 211-21
Publication
First Author: Okatsu K
Year: 2010
Journal: Genes Cells
Title: p62/SQSTM1 cooperates with Parkin for perinuclear clustering of depolarized mitochondria.
Volume: 15
Issue: 8
Pages: 887-900
Publication
First Author: Tran TA
Year: 2011
Journal: PLoS One
Title: Lipopolysaccharide and tumor necrosis factor regulate Parkin expression via nuclear factor-kappa B.
Volume: 6
Issue: 8
Pages: e23660
Publication
First Author: Iguchi M
Year: 2013
Journal: J Biol Chem
Title: Parkin-catalyzed ubiquitin-ester transfer is triggered by PINK1-dependent phosphorylation.
Volume: 288
Issue: 30
Pages: 22019-32
Publication
First Author: Gao B
Year: 2021
Journal: Biochim Biophys Acta Mol Basis Dis
Title: Parkin overexpression alleviates cardiac aging through facilitating K63-polyubiquitination of TBK1 to facilitate mitophagy.
Volume: 1867
Issue: 1
Pages: 165997
Publication  
First Author: Wang Y
Year: 2022
Journal: Redox Biol
Title: Ablation of Shank3 alleviates cardiac dysfunction in aging mice by promoting CaMKII activation and Parkin-mediated mitophagy.
Volume: 58
Pages: 102537
Publication
First Author: Ham SJ
Year: 2020
Journal: Proc Natl Acad Sci U S A
Title: Decision between mitophagy and apoptosis by Parkin via VDAC1 ubiquitination.
Volume: 117
Issue: 8
Pages: 4281-4291
Publication
First Author: Chen Y
Year: 2013
Journal: Science
Title: PINK1-phosphorylated mitofusin 2 is a Parkin receptor for culling damaged mitochondria.
Volume: 340
Issue: 6131
Pages: 471-5