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Search results 101 to 200 out of 2165 for Psen1

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Category: Publication
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Type Details Score
Publication
10526115 | J:57847
First Author: Zhu H
Year: 1999
Journal: Brain Res
Title: Dietary restriction protects hippocampal neurons against the death-promoting action of a presenilin-1 mutation.
Volume: 842
Issue: 1
Pages: 224-9
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Publication
12064358 | J:106192
First Author: LaFontaine MA
Year: 2002
Journal: Neurochem Res
Title: Oxidative stress in synaptosomal proteins from mutant presenilin-1 knock-in mice: implications for familial Alzheimer's disease.
Volume: 27
Issue: 5
Pages: 417-21
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Publication
18466334 | J:139367
First Author: Malik B
Year: 2008
Journal: J Neurochem
Title: Cell cycle-driven neuronal apoptosis specifically linked to amyloid peptide Abeta1-42 exposure is not exacerbated in a mouse model of presenilin-1 familial Alzheimer's disease.
Volume: 106
Issue: 2
Pages: 912-6
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Publication
10880403 | J:63138
First Author: Takeuchi A
Year: 2000
Journal: Am J Pathol
Title: Age-related amyloid beta deposition in transgenic mice overexpressing both Alzheimer mutant presenilin 1 and amyloid beta precursor protein Swedish mutant is not associated with global neuronal loss.
Volume: 157
Issue: 1
Pages: 331-9
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Publication
22496554 | J:184454
First Author: Watanabe H
Year: 2012
Journal: J Neurosci
Title: Familial frontotemporal dementia-associated presenilin-1 c.548G>T mutation causes decreased mRNA expression and reduced presenilin function in knock-in mice.
Volume: 32
Issue: 15
Pages: 5085-96
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Publication
18834536 | J:187802
 
First Author: Mirnics K
Year: 2008
Journal: Mol Neurodegener
Title: Molecular signatures of neurodegeneration in the cortex of PS1/PS2 double knockout mice.
Volume: 3
Pages: 14
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Publication
34329683 | J:312987
First Author: Sato K
Year: 2021
Journal: J Biol Chem
Title: A third-generation mouse model of Alzheimer's disease shows early and increased cored plaque pathology composed of wild-type human amyloid β peptide.
Volume: 297
Issue: 3
Pages: 101004
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Publication
30201812 | J:266223
First Author: Tanaka Y
Year: 2018
Journal: J Immunol
Title: Presenilin 1 Regulates NF-κB Activation via Association with Breakpoint Cluster Region and Casein Kinase II.
Volume: 201
Issue: 8
Pages: 2256-2263
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Publication
10821758 | J:62163
First Author: Handler M
Year: 2000
Journal: Development
Title: Presenilin-1 regulates neuronal differentiation during neurogenesis.
Volume: 127
Issue: 12
Pages: 2593-606
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Publication
31577226 | J:290203
   
First Author: Javier-Torrent M
Year: 2019
Journal: Elife
Title: Presenilin/γ-secretase-dependent EphA3 processing mediates axon elongation through non-muscle myosin IIA.
Volume: 8
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Publication
19005074 | J:142399
First Author: Tamboli IY
Year: 2008
Journal: J Neurosci
Title: Loss of gamma-secretase function impairs endocytosis of lipoprotein particles and membrane cholesterol homeostasis.
Volume: 28
Issue: 46
Pages: 12097-106
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Publication
17196556 | J:118185
First Author: Payette DJ
Year: 2007
Journal: Brain Res
Title: Reduction in CHT1-mediated choline uptake in primary neurons from presenilin-1 M146V mutant knock-in mice.
Volume: 1135
Issue: 1
Pages: 12-21
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Publication
12460542 | J:125448
First Author: Chan SL
Year: 2002
Journal: Neurobiol Dis
Title: Presenilin-1 mutations sensitize neurons to DNA damage-induced death by a mechanism involving perturbed calcium homeostasis and activation of calpains and caspase-12.
Volume: 11
Issue: 1
Pages: 2-19
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Publication
11822882 | J:74751
First Author: Gordon MN
Year: 2002
Journal: Exp Neurol
Title: Time course of the development of Alzheimer-like pathology in the doubly transgenic PS1+APP mouse.
Volume: 173
Issue: 2
Pages: 183-95
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Publication
33255764 | J:305084
 
First Author: Kartalou GI
Year: 2020
Journal: Int J Mol Sci
Title: Anti-Inflammatory Treatment with FTY720 Starting after Onset of Symptoms Reverses Synaptic Deficits in an AD Mouse Model.
Volume: 21
Issue: 23
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Publication
11476589 | J:71061
First Author: Jaffar S
Year: 2001
Journal: Exp Neurol
Title: Neuropathology of mice carrying mutant APP(swe) and/or PS1(M146L) transgenes: alterations in the p75(NTR) cholinergic basal forebrain septohippocampal pathway.
Volume: 170
Issue: 2
Pages: 227-43
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Publication
11896164 | J:75588
First Author: Jantzen PT
Year: 2002
Journal: J Neurosci
Title: Microglial activation and beta -amyloid deposit reduction caused by a nitric oxide-releasing nonsteroidal anti-inflammatory drug in amyloid precursor protein plus presenilin-1 transgenic mice.
Volume: 22
Issue: 6
Pages: 2246-54
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Publication
22393443 | J:185288
First Author: Trushina E
Year: 2012
Journal: PLoS One
Title: Defects in mitochondrial dynamics and metabolomic signatures of evolving energetic stress in mouse models of familial Alzheimer's disease.
Volume: 7
Issue: 2
Pages: e32737
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Publication
11493021 | J:71187
First Author: Poduslo JF
Year: 2001
Journal: Neurobiol Dis
Title: Permeability of proteins at the blood-brain barrier in the normal adult mouse and double transgenic mouse model of Alzheimer's disease.
Volume: 8
Issue: 4
Pages: 555-67
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Publication
20399254 | J:165240
First Author: Odero GL
Year: 2010
Journal: Neuroscience
Title: Evidence for the involvement of calbindin D28k in the presenilin 1 model of Alzheimer's disease.
Volume: 169
Issue: 1
Pages: 532-43
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Publication
22311977 | J:316671
First Author: Shilling D
Year: 2012
Journal: J Biol Chem
Title: Lack of evidence for presenilins as endoplasmic reticulum Ca2+ leak channels.
Volume: 287
Issue: 14
Pages: 10933-44
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Publication
20359773 | J:188249
First Author: Gengler S
Year: 2012
Journal: Neurobiol Aging
Title: Val(8)GLP-1 rescues synaptic plasticity and reduces dense core plaques in APP/PS1 mice.
Volume: 33
Issue: 2
Pages: 265-76
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Publication
11520121 | J:71666
First Author: Kurt MA
Year: 2001
Journal: Exp Neurol
Title: Neurodegenerative changes associated with beta-amyloid deposition in the brains of mice carrying mutant amyloid precursor protein and mutant presenilin-1 transgenes.
Volume: 171
Issue: 1
Pages: 59-71
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Publication
9427614 | J:45724
First Author: Holcomb L
Year: 1998
Journal: Nat Med
Title: Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenes.
Volume: 4
Issue: 1
Pages: 97-100
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15207348 | J:91277
First Author: Wang R
Year: 2004
Journal: Neuroscience
Title: Presenilin 1 familial Alzheimer's disease mutation leads to defective associative learning and impaired adult neurogenesis.
Volume: 126
Issue: 2
Pages: 305-12
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Publication
24145027 | J:209333
First Author: Almenar-Queralt A
Year: 2013
Journal: J Biol Chem
Title: Presenilins regulate neurotrypsin gene expression and neurotrypsin-dependent agrin cleavage via cyclic AMP response element-binding protein (CREB) modulation.
Volume: 288
Issue: 49
Pages: 35222-36
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Publication
28739891 | J:244685
First Author: Keskin AD
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: BACE inhibition-dependent repair of Alzheimer's pathophysiology.
Volume: 114
Issue: 32
Pages: 8631-8636
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Publication
12805290 | J:83886
First Author: Pigino G
Year: 2003
Journal: J Neurosci
Title: Alzheimer's presenilin 1 mutations impair kinesin-based axonal transport.
Volume: 23
Issue: 11
Pages: 4499-508
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Publication
17222948 | J:137684
First Author: Dewachter I
Year: 2008
Journal: Neurobiol Aging
Title: Modulation of synaptic plasticity and Tau phosphorylation by wild-type and mutant presenilin1.
Volume: 29
Issue: 5
Pages: 639-52
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Publication
10964951 | J:64209
First Author: Dewachter I
Year: 2000
Journal: J Neurosci
Title: Aging increased amyloid peptide and caused amyloid plaques in brain of old APP/V717I transgenic mice by a different mechanism than mutant presenilin1.
Volume: 20
Issue: 17
Pages: 6452-8
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Publication
16574645 | J:113453
First Author: Wang R
Year: 2006
Journal: J Biol Chem
Title: Wild-type presenilin 1 protects against Alzheimer disease mutation-induced amyloid pathology.
Volume: 281
Issue: 22
Pages: 15330-6
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Publication
8878479 | J:80861
First Author: Duff K
Year: 1996
Journal: Nature
Title: Increased amyloid-beta42(43) in brains of mice expressing mutant presenilin 1.
Volume: 383
Issue: 6602
Pages: 710-3
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10037474 | J:53131
First Author: Begley JG
Year: 1999
Journal: J Neurochem
Title: Altered calcium homeostasis and mitochondrial dysfunction in cortical synaptic compartments of presenilin-1 mutant mice.
Volume: 72
Issue: 3
Pages: 1030-9
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38462606 | J:347713
First Author: Zhong MZ
Year: 2024
Journal: Mol Neurodegener
Title: Updates on mouse models of Alzheimer's disease.
Volume: 19
Issue: 1
Pages: 23
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32993686 | J:313508
First Author: Robison LS
Year: 2020
Journal: J Neuroinflammation
Title: Role of sex and high-fat diet in metabolic and hypothalamic disturbances in the 3xTg-AD mouse model of Alzheimer's disease.
Volume: 17
Issue: 1
Pages: 285
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17472708 | J:124130
First Author: Oddo S
Year: 2007
Journal: J Neurochem
Title: Genetically augmenting tau levels does not modulate the onset or progression of Abeta pathology in transgenic mice.
Volume: 102
Issue: 4
Pages: 1053-63
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22095718 | J:180375
First Author: Kitazawa M
Year: 2011
Journal: J Immunol
Title: Blocking IL-1 signaling rescues cognition, attenuates tau pathology, and restores neuronal β-catenin pathway function in an Alzheimer's disease model.
Volume: 187
Issue: 12
Pages: 6539-49
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27897204 | J:287498
 
First Author: Oka S
Year: 2016
Journal: Sci Rep
Title: Human mitochondrial transcriptional factor A breaks the mitochondria-mediated vicious cycle in Alzheimer's disease.
Volume: 6
Pages: 37889
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Publication
15748844 | J:99604
First Author: Billings LM
Year: 2005
Journal: Neuron
Title: Intraneuronal Abeta causes the onset of early Alzheimer's disease-related cognitive deficits in transgenic mice.
Volume: 45
Issue: 5
Pages: 675-88
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31065079 | J:279862
First Author: Li G
Year: 2019
Journal: Sci Rep
Title: High-throughput metabolomics and ingenuity pathway approach reveals the pharmacological effect and targets of Ginsenoside Rg1 in Alzheimer's disease mice.
Volume: 9
Issue: 1
Pages: 7040
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32619874 | J:298311
 
First Author: Vanzulli I
Year: 2020
Journal: Neurobiol Aging
Title: Disruption of oligodendrocyte progenitor cells is an early sign of pathology in the triple transgenic mouse model of Alzheimer's disease.
Volume: 94
Pages: 130-139
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36950017 | J:345220
 
First Author: Zhou X
Year: 2023
Journal: Front Pharmacol
Title: Evaluation of therapeutic effects of tetramethylpyrazine nitrone in Alzheimer's disease mouse model and proteomics analysis.
Volume: 14
Pages: 1082602
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29760653 | J:324368
 
First Author: Zhang Q
Year: 2018
Journal: Front Mol Neurosci
Title: CK2 Phosphorylating I2PP2A/SET Mediates Tau Pathology and Cognitive Impairment.
Volume: 11
Pages: 146
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17456772 | J:121081
First Author: Caccamo A
Year: 2007
Journal: Am J Pathol
Title: Lithium reduces tau phosphorylation but not A beta or working memory deficits in a transgenic model with both plaques and tangles.
Volume: 170
Issue: 5
Pages: 1669-75
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31813629 | J:298321
 
First Author: Bonfili L
Year: 2020
Journal: Neurobiol Aging
Title: Gut microbiota manipulation through probiotics oral administration restores glucose homeostasis in a mouse model of Alzheimer's disease.
Volume: 87
Pages: 35-43
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37884161 | J:342442
 
First Author: Park H
Year: 2023
Journal: Brain Behav Immun
Title: GV1001 modulates neuroinflammation and improves memory and behavior through the activation of gonadotropin-releasing hormone receptors in a triple transgenic Alzheimer's disease mouse model.
Volume: 115
Pages: 295-307
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21983102 | J:177424
First Author: Dolan PJ
Year: 2011
Journal: FEBS Lett
Title: Decreases in valosin-containing protein result in increased levels of tau phosphorylated at Ser262/356.
Volume: 585
Issue: 21
Pages: 3424-9
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17442823 | J:121088
First Author: Green KN
Year: 2007
Journal: J Neurosci
Title: Dietary docosahexaenoic acid and docosapentaenoic acid ameliorate amyloid-beta and tau pathology via a mechanism involving presenilin 1 levels.
Volume: 27
Issue: 16
Pages: 4385-95
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23932880 | J:211983
First Author: Wang Y
Year: 2014
Journal: Neurobiol Aging
Title: L-type Ca2+ currents at CA1 synapses, but not CA3 or dentate granule neuron synapses, are increased in 3xTgAD mice in an age-dependent manner.
Volume: 35
Issue: 1
Pages: 88-95
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26247694 | J:226259
 
First Author: Leirós M
Year: 2015
Journal: Neuroscience
Title: The Streptomyces metabolite anhydroexfoliamycin ameliorates hallmarks of Alzheimer's disease in vitro and in vivo.
Volume: 305
Pages: 26-35
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37619698 | J:339650
 
First Author: Philipsberg PA
Year: 2023
Journal: Neurosci Lett
Title: Chronotate: An open-source tool for manual timestamping and quantification of animal behavior.
Volume: 814
Pages: 137461
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24144550 | J:207948
 
First Author: Baeta-Corral R
Year: 2014
Journal: Behav Brain Res
Title: Bizarre behaviors and risk assessment in 3xTg-AD mice at early stages of the disease.
Volume: 258
Pages: 97-105
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35961538 | J:328004
 
First Author: Castillo-Mariqueo L
Year: 2022
Journal: Behav Brain Res
Title: Clasping, ledge-score coordination and early gait impairments as primary behavioural markers of functional impairment in Alzheimer's disease.
Volume: 435
Pages: 114054
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36801910 | J:338580
First Author: Liu Y
Year: 2023
Journal: Cell Death Dis
Title: Early postnatal defects in neurogenesis in the 3xTg mouse model of Alzheimer's disease.
Volume: 14
Issue: 2
Pages: 138
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35153718 | J:321582
 
First Author: Tureckova J
Year: 2021
Journal: Front Aging Neurosci
Title: Compromised Astrocyte Swelling/Volume Regulation in the Hippocampus of the Triple Transgenic Mouse Model of Alzheimer's Disease.
Volume: 13
Pages: 783120
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31427644 | J:283838
First Author: Pietronigro E
Year: 2019
Journal: Sci Rep
Title: Blockade of α4 integrins reduces leukocyte-endothelial interactions in cerebral vessels and improves memory in a mouse model of Alzheimer's disease.
Volume: 9
Issue: 1
Pages: 12055
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32916195 | J:299673
 
First Author: Sarlus H
Year: 2020
Journal: Neuroscience
Title: Chronic Airway Allergy Induces Pro-Inflammatory Responses in the Brain of Wildtype Mice but Not 3xTgAD Mice.
Volume: 448
Pages: 14-27
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24918340 | J:217129
 
First Author: Chen Y
Year: 2014
Journal: Exp Neurol
Title: Intranasal insulin restores insulin signaling, increases synaptic proteins, and reduces Aβ level and microglia activation in the brains of 3xTg-AD mice.
Volume: 261
Pages: 610-9
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18374906 | J:285087
 
First Author: McKee AC
Year: 2008
Journal: Brain Res
Title: Ibuprofen reduces Abeta, hyperphosphorylated tau and memory deficits in Alzheimer mice.
Volume: 1207
Pages: 225-36
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30071370 | J:271557
 
First Author: Bourgeois A
Year: 2018
Journal: Neurobiol Aging
Title: Intraneuronal accumulation of C99 contributes to synaptic alterations, apathy-like behavior, and spatial learning deficits in 3×TgAD and 2×TgAD mice.
Volume: 71
Pages: 21-31
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19183260 | J:146855
First Author: Kitazawa M
Year: 2009
Journal: J Neurochem
Title: Chronic copper exposure exacerbates both amyloid and tau pathology and selectively dysregulates cdk5 in a mouse model of AD.
Volume: 108
Issue: 6
Pages: 1550-60
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34798170 | J:322281
 
First Author: Yao L
Year: 2022
Journal: Behav Brain Res
Title: OGDHL ameliorates cognitive impairment and Alzheimer's disease-like pathology via activating Wnt/β-catenin signaling in Alzheimer's disease mice.
Volume: 418
Pages: 113673
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31103943 | J:281609
 
First Author: Castano-Prat P
Year: 2019
Journal: Neurobiol Aging
Title: Altered slow (<1 Hz) and fast (beta and gamma) neocortical oscillations in the 3xTg-AD mouse model of Alzheimer's disease under anesthesia.
Volume: 79
Pages: 142-151
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23312564 | J:284611
First Author: Baglietto-Vargas D
Year: 2013
Journal: Biol Psychiatry
Title: Mifepristone alters amyloid precursor protein processing to preclude amyloid beta and also reduces tau pathology.
Volume: 74
Issue: 5
Pages: 357-66
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26857506 | J:230426
First Author: Winston CN
Year: 2016
Journal: Am J Pathol
Title: Dendritic Spine Loss and Chronic White Matter Inflammation in a Mouse Model of Highly Repetitive Head Trauma.
Volume: 186
Issue: 3
Pages: 552-67
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35645744 | J:325703
 
First Author: Tucker AE
Year: 2022
Journal: Front Behav Neurosci
Title: Chronic Ethanol Causes Persistent Increases in Alzheimer's Tau Pathology in Female 3xTg-AD Mice: A Potential Role for Lysosomal Impairment.
Volume: 16
Pages: 886634
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22516463 | J:188750
First Author: Peng J
Year: 2012
Journal: Neurosci Lett
Title: Dantrolene ameliorates cognitive decline and neuropathology in Alzheimer triple transgenic mice.
Volume: 516
Issue: 2
Pages: 274-9
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31427599 | J:284641
First Author: Park SJ
Year: 2019
Journal: Sci Rep
Title: Visualizing Alzheimer's Disease Mouse Brain with Multispectral Optoacoustic Tomography using a Fluorescent probe, CDnir7.
Volume: 9
Issue: 1
Pages: 12052
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26778963 | J:310589
 
First Author: Piedrahita D
Year: 2015
Journal: Front Cell Neurosci
Title: β-Secretase 1's Targeting Reduces Hyperphosphorilated Tau, Implying Autophagy Actors in 3xTg-AD Mice.
Volume: 9
Pages: 498
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24022509 | J:202026
 
First Author: Barak B
Year: 2013
Journal: Transl Psychiatry
Title: Opposing actions of environmental enrichment and Alzheimer's disease on the expression of hippocampal microRNAs in mouse models.
Volume: 3
Pages: e304
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24655393 | J:217239
First Author: Ghosh D
Year: 2014
Journal: Aging Cell
Title: Relative importance of redox buffers GSH and NAD(P)H in age-related neurodegeneration and Alzheimer disease-like mouse neurons.
Volume: 13
Issue: 4
Pages: 631-40
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20673763 | J:165298
First Author: Hyun DH
Year: 2010
Journal: Exp Neurol
Title: The plasma membrane redox system is impaired by amyloid β-peptide and in the hippocampus and cerebral cortex of 3xTgAD mice.
Volume: 225
Issue: 2
Pages: 423-9
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28511979 | J:249623
 
First Author: Davis KE
Year: 2017
Journal: Behav Brain Res
Title: Water and T-maze protocols are equally efficient methods to assess spatial memory in 3xTg Alzheimer's disease mice.
Volume: 331
Pages: 54-66
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31055081 | J:283443
First Author: Fanaee-Danesh E
Year: 2019
Journal: Biochim Biophys Acta Mol Basis Dis
Title: Astaxanthin exerts protective effects similar to bexarotene in Alzheimer's disease by modulating amyloid-beta and cholesterol homeostasis in blood-brain barrier endothelial cells.
Volume: 1865
Issue: 9
Pages: 2224-2245
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25857617 | J:230543
First Author: Mota SI
Year: 2015
Journal: Biochim Biophys Acta
Title: Oxidative stress involving changes in Nrf2 and ER stress in early stages of Alzheimer's disease.
Volume: 1852
Issue: 7
Pages: 1428-41
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28688899 | J:249714
 
First Author: Velazquez R
Year: 2017
Journal: Neurobiol Aging
Title: Central insulin dysregulation and energy dyshomeostasis in two mouse models of Alzheimer's disease.
Volume: 58
Pages: 1-13
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26939023 | J:249723
First Author: Makani V
Year: 2016
Journal: PLoS One
Title: BBB-Permeable, Neuroprotective, and Neurotrophic Polysaccharide, Midi-GAGR.
Volume: 11
Issue: 3
Pages: e0149715
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28941799 | J:254181
First Author: Zandl-Lang M
Year: 2018
Journal: Biochim Biophys Acta
Title: Regulatory effects of simvastatin and apoJ on APP processing and amyloid-β clearance in blood-brain barrier endothelial cells.
Volume: 1863
Issue: 1
Pages: 40-60
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36915108 | J:334972
First Author: Wang RP
Year: 2023
Journal: J Neuroinflammation
Title: IL-1β and TNF-α play an important role in modulating the risk of periodontitis and Alzheimer's disease.
Volume: 20
Issue: 1
Pages: 71
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Publication
34896306 | J:319782
 
First Author: Nazari HK
Year: 2022
Journal: Exp Eye Res
Title: Age dependence of retinal vascular plexus attenuation in the triple transgenic mouse model of Alzheimer's disease.
Volume: 214
Pages: 108879
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Publication
36902113 | J:348454
 
First Author: Webberley TS
Year: 2023
Journal: Int J Mol Sci
Title: Assessment of Lab4P Probiotic Effects on Cognition in 3xTg-AD Alzheimer's Disease Model Mice and the SH-SY5Y Neuronal Cell Line.
Volume: 24
Issue: 5
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Publication
31150495 | J:276449
First Author: Esquerda-Canals G
Year: 2019
Journal: PLoS One
Title: Pharmacokinetic parameters and mechanism of action of an efficient anti-Aβ single chain antibody fragment.
Volume: 14
Issue: 5
Pages: e0217793
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Publication
28865961 | J:307498
First Author: Sah SK
Year: 2017
Journal: Biochem Biophys Res Commun
Title: Effect of high-fat diet on cognitive impairment in triple-transgenic mice model of Alzheimer's disease.
Volume: 493
Issue: 1
Pages: 731-736
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Publication
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