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Search results 2001 to 2100 out of 2165 for Psen1

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Category: Publication
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Type Details Score
Publication
11164808 | J:128650
First Author: Arendash GW
Year: 2001
Journal: Brain Res
Title: Progressive, age-related behavioral impairments in transgenic mice carrying both mutant amyloid precursor protein and presenilin-1 transgenes.
Volume: 891
Issue: 1-2
Pages: 42-53
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Publication
19805389 | J:153208
First Author: Smith DL
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Reversal of long-term dendritic spine alterations in Alzheimer disease models.
Volume: 106
Issue: 39
Pages: 16877-82
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Publication
20451607 | J:164930
First Author: Braithwaite SP
Year: 2010
Journal: Neurobiol Dis
Title: Inhibition of c-Jun kinase provides neuroprotection in a model of Alzheimer's disease.
Volume: 39
Issue: 3
Pages: 311-7
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Publication
15330337 | J:312751
First Author: Cataldo AM
Year: 2004
Journal: J Neuropathol Exp Neurol
Title: Presenilin mutations in familial Alzheimer disease and transgenic mouse models accelerate neuronal lysosomal pathology.
Volume: 63
Issue: 8
Pages: 821-30
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Publication
23468919 | J:197172
First Author: Wadghiri YZ
Year: 2013
Journal: PLoS One
Title: Detection of amyloid plaques targeted by bifunctional USPIO in Alzheimer's disease transgenic mice using magnetic resonance microimaging.
Volume: 8
Issue: 2
Pages: e57097
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Publication
24316473 | J:208026
 
First Author: Marjańska M
Year: 2014
Journal: Neuroscience
Title: Treatment effects in a transgenic mouse model of Alzheimer's disease: a magnetic resonance spectroscopy study after passive immunization.
Volume: 259
Pages: 94-100
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Publication
34659251 | J:312699
 
First Author: Antequera D
Year: 2021
Journal: Front Immunol
Title: Salivary Lactoferrin Expression in a Mouse Model of Alzheimer's Disease.
Volume: 12
Pages: 749468
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Publication
11796757 | J:73607
First Author: Zheng H
Year: 2002
Journal: J Neurochem
Title: Modulation of A(beta) peptides by estrogen in mouse models.
Volume: 80
Issue: 1
Pages: 191-6
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Publication
26315370 | J:232251
First Author: Varnum MM
Year: 2015
Journal: Neurobiol Aging
Title: The anti-inflammatory glycoprotein, CD200, restores neurogenesis and enhances amyloid phagocytosis in a mouse model of Alzheimer's disease.
Volume: 36
Issue: 11
Pages: 2995-3007
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Publication
23595759 | J:196964
First Author: Corbett BF
Year: 2013
Journal: J Neurosci
Title: Sodium channel cleavage is associated with aberrant neuronal activity and cognitive deficits in a mouse model of Alzheimer's disease.
Volume: 33
Issue: 16
Pages: 7020-6
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Publication
11290552 | J:68670
First Author: Matsuoka Y
Year: 2001
Journal: Am J Pathol
Title: Inflammatory responses to amyloidosis in a transgenic mouse model of Alzheimer's disease.
Volume: 158
Issue: 4
Pages: 1345-54
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Publication
16091461 | J:101060
First Author: Marjanska M
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: Monitoring disease progression in transgenic mouse models of Alzheimer's disease with proton magnetic resonance spectroscopy.
Volume: 102
Issue: 33
Pages: 11906-10
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Publication
29477640 | J:268459
 
First Author: Zhang L
Year: 2018
Journal: Neurobiol Dis
Title: Differential effect of amyloid beta peptides on mitochondrial axonal trafficking depends on their state of aggregation and binding to the plasma membrane.
Volume: 114
Pages: 1-16
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Publication
16733088 | J:111313
First Author: Ethell DW
Year: 2006
Journal: Neurobiol Dis
Title: Abeta-specific T-cells reverse cognitive decline and synaptic loss in Alzheimer's mice.
Volume: 23
Issue: 2
Pages: 351-61
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Publication
16460878 | J:106997
First Author: Noda-Saita K
Year: 2006
Journal: Neuroscience
Title: Quantitative analysis of amyloid plaques in a mouse model of Alzheimer's disease by phase-contrast X-ray computed tomography.
Volume: 138
Issue: 4
Pages: 1205-13
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Publication
26566997 | J:340366
 
First Author: Xu G
Year: 2015
Journal: Acta Neuropathol Commun
Title: Murine Aβ over-production produces diffuse and compact Alzheimer-type amyloid deposits.
Volume: 3
Pages: 72
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Publication
30373880 | J:269026
First Author: Wang ZH
Year: 2018
Journal: J Exp Med
Title: Delta-secretase (AEP) mediates tau-splicing imbalance and accelerates cognitive decline in tauopathies.
Volume: 215
Issue: 12
Pages: 3038-3056
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Publication
32595447 | J:311244
 
First Author: Loeffler T
Year: 2020
Journal: Front Neurosci
Title: Neurofilament-Light Chain as Biomarker of Neurodegenerative and Rare Diseases With High Translational Value.
Volume: 14
Pages: 579
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Publication
35394029 | J:324255
 
First Author: Koller EJ
Year: 2022
Journal: Dis Model Mech
Title: Temporal and spatially controlled APP transgene expression using Cre-dependent alleles.
Volume: 15
Issue: 5
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Publication
36352225 | J:339995
First Author: Drieu A
Year: 2022
Journal: Nature
Title: Parenchymal border macrophages regulate the flow dynamics of the cerebrospinal fluid.
Volume: 611
Issue: 7936
Pages: 585-593
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Publication
34262178 | J:335093
First Author: McAlpine CS
Year: 2021
Journal: Nature
Title: Astrocytic interleukin-3 programs microglia and limits Alzheimer's disease.
Volume: 595
Issue: 7869
Pages: 701-706
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Publication
30046111 | J:265289
First Author: Da Mesquita S
Year: 2018
Journal: Nature
Title: Functional aspects of meningeal lymphatics in ageing and Alzheimer's disease.
Volume: 560
Issue: 7717
Pages: 185-191
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Publication
28602351 | J:324482
First Author: Keren-Shaul H
Year: 2017
Journal: Cell
Title: A Unique Microglia Type Associated with Restricting Development of Alzheimer's Disease.
Volume: 169
Issue: 7
Pages: 1276-1290.e17
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Publication
37541210 | J:339355
First Author: Yoo Y
Year: 2023
Journal: Cell Stem Cell
Title: A cell therapy approach to restore microglial Trem2 function in a mouse model of Alzheimer's disease.
Volume: 30
Issue: 8
Pages: 1043-1053.e6
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Publication
35573205 | J:328754
First Author: Takahashi F
Year: 2022
Journal: iScience
Title: Immune-mediated neurodegenerative trait provoked by multimodal derepression of long-interspersed nuclear element-1.
Volume: 25
Issue: 5
Pages: 104278
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Publication
33076948 | J:303244
First Author: Serneels L
Year: 2020
Journal: Mol Neurodegener
Title: Modeling the β-secretase cleavage site and humanizing amyloid-beta precursor protein in rat and mouse to study Alzheimer's disease.
Volume: 15
Issue: 1
Pages: 60
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Publication
29859094 | J:264653
First Author: Cheng-Hathaway PJ
Year: 2018
Journal: Mol Neurodegener
Title: The Trem2 R47H variant confers loss-of-function-like phenotypes in Alzheimer's disease.
Volume: 13
Issue: 1
Pages: 29
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Publication
30911686 | J:278879
 
First Author: Woo JA
Year: 2019
Journal: Commun Biol
Title: Activated cofilin exacerbates tau pathology by impairing tau-mediated microtubule dynamics.
Volume: 2
Pages: 112
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Publication
29724785 | J:265685
First Author: Reichenbach N
Year: 2018
Journal: J Exp Med
Title: P2Y1 receptor blockade normalizes network dysfunction and cognition in an Alzheimer's disease model.
Volume: 215
Issue: 6
Pages: 1649-1663
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Publication
16774924 | J:116517
First Author: Culbert AA
Year: 2006
Journal: J Biol Chem
Title: MAPK-activated protein kinase 2 deficiency in microglia inhibits pro-inflammatory mediator release and resultant neurotoxicity. Relevance to neuroinflammation in a transgenic mouse model of Alzheimer disease.
Volume: 281
Issue: 33
Pages: 23658-67
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Publication
18467698 | J:136190
First Author: Ermini FV
Year: 2008
Journal: Am J Pathol
Title: Neurogenesis and alterations of neural stem cells in mouse models of cerebral amyloidosis.
Volume: 172
Issue: 6
Pages: 1520-8
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Publication
14751770 | J:128645
First Author: Boutajangout A
Year: 2004
Journal: Neurobiol Dis
Title: Characterisation of cytoskeletal abnormalities in mice transgenic for wild-type human tau and familial Alzheimer's disease mutants of APP and presenilin-1.
Volume: 15
Issue: 1
Pages: 47-60
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Publication
15921918 | J:102542
First Author: Köhler C
Year: 2005
Journal: Neurobiol Dis
Title: Alzheimer's disease-like neuropathology of gene-targeted APP-SLxPS1mut mice expressing the amyloid precursor protein at endogenous levels.
Volume: 20
Issue: 2
Pages: 528-40
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Publication
28637503 | J:312842
First Author: Steffen J
Year: 2017
Journal: Acta Neuropathol Commun
Title: Expression of endogenous mouse APP modulates β-amyloid deposition in hAPP-transgenic mice.
Volume: 5
Issue: 1
Pages: 49
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Publication
31235932 | J:281622
First Author: Leyns CEG
Year: 2019
Journal: Nat Neurosci
Title: TREM2 function impedes tau seeding in neuritic plaques.
Volume: 22
Issue: 8
Pages: 1217-1222
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Publication
23178247 | J:194214
First Author: Vom Berg J
Year: 2012
Journal: Nat Med
Title: Inhibition of IL-12/IL-23 signaling reduces Alzheimer's disease-like pathology and cognitive decline.
Volume: 18
Issue: 12
Pages: 1812-9
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Publication
23999102 | J:204530
First Author: Heilbronner G
Year: 2013
Journal: EMBO Rep
Title: Seeded strain-like transmission of β-amyloid morphotypes in APP transgenic mice.
Volume: 14
Issue: 11
Pages: 1017-22
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Publication
23100432 | J:192173
First Author: Cameron B
Year: 2012
Journal: J Neurosci
Title: Loss of interleukin receptor-associated kinase 4 signaling suppresses amyloid pathology and alters microglial phenotype in a mouse model of Alzheimer's disease.
Volume: 32
Issue: 43
Pages: 15112-23
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Publication
19213921 | J:144934
First Author: Thathiah A
Year: 2009
Journal: Science
Title: The orphan G protein-coupled receptor 3 modulates amyloid-beta peptide generation in neurons.
Volume: 323
Issue: 5916
Pages: 946-51
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Publication
24893973 | J:241976
 
First Author: Ulrich JD
Year: 2014
Journal: Mol Neurodegener
Title: Altered microglial response to Aβ plaques in APPPS1-21 mice heterozygous for TREM2.
Volume: 9
Pages: 20
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Publication
26458768 | J:229027
First Author: Prokop S
Year: 2015
Journal: J Exp Med
Title: Impact of peripheral myeloid cells on amyloid-β pathology in Alzheimer's disease-like mice.
Volume: 212
Issue: 11
Pages: 1811-8
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Publication
28701326 | J:249736
First Author: Ye L
Year: 2017
Journal: EMBO Rep
Title: Aβ seeding potency peaks in the early stages of cerebral β-amyloidosis.
Volume: 18
Issue: 9
Pages: 1536-1544
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Publication
18077058 | J:152963
First Author: Priller C
Year: 2009
Journal: Neurobiol Aging
Title: Excitatory synaptic transmission is depressed in cultured hippocampal neurons of APP/PS1 mice.
Volume: 30
Issue: 8
Pages: 1227-37
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Publication
36443293 | J:331959
First Author: Rother C
Year: 2022
Journal: Nat Commun
Title: Experimental evidence for temporal uncoupling of brain Aβ deposition and neurodegenerative sequelae.
Volume: 13
Issue: 1
Pages: 7333
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25911278 | J:224496
First Author: Mahler J
Year: 2015
Journal: Neurobiol Aging
Title: Endogenous murine Aβ increases amyloid deposition in APP23 but not in APPPS1 transgenic mice.
Volume: 36
Issue: 7
Pages: 2241-2247
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Publication
29472246 | J:262255
 
First Author: Steeland S
Year: 2018
Journal: EMBO Mol Med
Title: Counteracting the effects of TNF receptor-1 has therapeutic potential in Alzheimer's disease.
Volume: 10
Issue: 4
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Publication
30667373 | J:270447
First Author: Beckelman BC
Year: 2019
Journal: J Clin Invest
Title: Genetic reduction of eEF2 kinase alleviates pathophysiology in Alzheimer's disease model mice.
Volume: 129
Issue: 2
Pages: 820-833
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Publication
28768717 | J:248773
First Author: Agís-Balboa RC
Year: 2017
Journal: EMBO J
Title: Formin 2 links neuropsychiatric phenotypes at young age to an increased risk for dementia.
Volume: 36
Issue: 19
Pages: 2815-2828
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Publication
36611872 | J:332599
 
First Author: Rudan Njavro J
Year: 2022
Journal: Cells
Title: Beneficial Effect of ACI-24 Vaccination on Aβ Plaque Pathology and Microglial Phenotypes in an Amyloidosis Mouse Model.
Volume: 12
Issue: 1
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Publication
26663083 | J:259402
First Author: Schnöder L
Year: 2016
Journal: J Biol Chem
Title: Deficiency of Neuronal p38α MAPK Attenuates Amyloid Pathology in Alzheimer Disease Mouse and Cell Models through Facilitating Lysosomal Degradation of BACE1.
Volume: 291
Issue: 5
Pages: 2067-79
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Publication
25675483 | J:220176
First Author: Han BH
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Contribution of reactive oxygen species to cerebral amyloid angiopathy, vasomotor dysfunction, and microhemorrhage in aged Tg2576 mice.
Volume: 112
Issue: 8
Pages: E881-90
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Publication
31122931 | J:284721
 
First Author: Götzl JK
Year: 2019
Journal: EMBO Mol Med
Title: Opposite microglial activation stages upon loss of PGRN or TREM2 result in reduced cerebral glucose metabolism.
Volume: 11
Issue: 6
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31473905 | J:344796
First Author: Gil-Iturbe E
Year: 2020
Journal: Mol Neurobiol
Title: GLUT12 Expression in Brain of Mouse Models of Alzheimer's Disease.
Volume: 57
Issue: 2
Pages: 798-805
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21228171 | J:180835
First Author: Hefendehl JK
Year: 2011
Journal: J Neurosci
Title: Long-term in vivo imaging of β-amyloid plaque appearance and growth in a mouse model of cerebral β-amyloidosis.
Volume: 31
Issue: 2
Pages: 624-9
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Publication
24465508 | J:212342
First Author: Bitsikas V
Year: 2014
Journal: PLoS One
Title: The role of flotillins in regulating aβ production, investigated using flotillin 1-/-, flotillin 2-/- double knockout mice.
Volume: 9
Issue: 1
Pages: e85217
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Publication
20970889 | J:188225
First Author: Rupp NJ
Year: 2011
Journal: Neurobiol Aging
Title: Early onset amyloid lesions lead to severe neuritic abnormalities and local, but not global neuron loss in APPPS1 transgenic mice.
Volume: 32
Issue: 12
Pages: 2324.e1-6
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Publication
34033742 | J:324406
First Author: Walgrave H
Year: 2021
Journal: Cell Stem Cell
Title: Restoring miR-132 expression rescues adult hippocampal neurogenesis and memory deficits in Alzheimer's disease.
Volume: 28
Issue: 10
Pages: 1805-1821.e8
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Publication
30341179 | J:269291
First Author: Rush T
Year: 2018
Journal: J Neurosci
Title: Synaptotoxicity in Alzheimer's Disease Involved a Dysregulation of Actin Cytoskeleton Dynamics through Cofilin 1 Phosphorylation.
Volume: 38
Issue: 48
Pages: 10349-10361
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Publication
30617257 | J:277170
First Author: Parhizkar S
Year: 2019
Journal: Nat Neurosci
Title: Loss of TREM2 function increases amyloid seeding but reduces plaque-associated ApoE.
Volume: 22
Issue: 2
Pages: 191-204
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Publication
32510331 | J:290216
   
First Author: Sebastian Monasor L
Year: 2020
Journal: Elife
Title: Fibrillar Aβ triggers microglial proteome alterations and dysfunction in Alzheimer mouse models.
Volume: 9
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26099047 | J:224864
First Author: Bachhuber T
Year: 2015
Journal: Nat Med
Title: Inhibition of amyloid-β plaque formation by α-synuclein.
Volume: 21
Issue: 7
Pages: 802-7
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Publication
23863834 | J:213474
First Author: Maia LF
Year: 2013
Journal: Sci Transl Med
Title: Changes in amyloid-β and Tau in the cerebrospinal fluid of transgenic mice overexpressing amyloid precursor protein.
Volume: 5
Issue: 194
Pages: 194re2
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Publication
25315299 | J:230461
First Author: Barone E
Year: 2014
Journal: Biochim Biophys Acta
Title: Inactivation of brain Cofilin-1 by age, Alzheimer's disease and γ-secretase.
Volume: 1842
Issue: 12 Pt A
Pages: 2500-9
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Publication
28877763 | J:338512
First Author: Schweig JE
Year: 2017
Journal: Acta Neuropathol Commun
Title: Alzheimer's disease pathological lesions activate the spleen tyrosine kinase.
Volume: 5
Issue: 1
Pages: 69
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Publication
15311281 | J:92796
First Author: Herzig MC
Year: 2004
Journal: Nat Neurosci
Title: Abeta is targeted to the vasculature in a mouse model of hereditary cerebral hemorrhage with amyloidosis.
Volume: 7
Issue: 9
Pages: 954-60
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Publication
17596707 | J:162531
First Author: Herzig MC
Year: 2007
Journal: Neurodegener Dis
Title: BACE1 and mutated presenilin-1 differently modulate Abeta40 and Abeta42 levels and cerebral amyloidosis in APPDutch transgenic mice.
Volume: 4
Issue: 2-3
Pages: 127-35
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17673336 | J:145815
First Author: Dewachter I
Year: 2009
Journal: Neurobiol Aging
Title: Deregulation of NMDA-receptor function and down-stream signaling in APP[V717I] transgenic mice.
Volume: 30
Issue: 2
Pages: 241-56
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Publication
27421117 | J:252385
First Author: Hansen HH
Year: 2016
Journal: PLoS One
Title: Long-Term Treatment with Liraglutide, a Glucagon-Like Peptide-1 (GLP-1) Receptor Agonist, Has No Effect on β-Amyloid Plaque Load in Two Transgenic APP/PS1 Mouse Models of Alzheimer's Disease.
Volume: 11
Issue: 7
Pages: e0158205
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11021833 | J:129692
First Author: Van Dorpe J
Year: 2000
Journal: Am J Pathol
Title: Prominent cerebral amyloid angiopathy in transgenic mice overexpressing the london mutant of human APP in neurons.
Volume: 157
Issue: 4
Pages: 1283-98
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11744223 | J:108752
First Author: Wirths O
Year: 2001
Journal: Neurosci Lett
Title: Reelin in plaques of beta-amyloid precursor protein and presenilin-1 double-transgenic mice.
Volume: 316
Issue: 3
Pages: 145-8
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Publication
21248127 | J:168561
First Author: Beckmann N
Year: 2011
Journal: J Neurosci
Title: Noninvasive magnetic resonance imaging detection of cerebral amyloid angiopathy-related microvascular alterations using superparamagnetic iron oxide particles in APP transgenic mouse models of Alzheimer's disease: application to passive Abeta immunotherapy.
Volume: 31
Issue: 3
Pages: 1023-31
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23202730 | J:194181
First Author: Ly PT
Year: 2013
Journal: J Clin Invest
Title: Inhibition of GSK3β-mediated BACE1 expression reduces Alzheimer-associated phenotypes.
Volume: 123
Issue: 1
Pages: 224-35
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23040664 | J:203385
First Author: Kiyota T
Year: 2013
Journal: Neurobiol Aging
Title: CCL2 affects β-amyloidosis and progressive neurocognitive dysfunction in a mouse model of Alzheimer's disease.
Volume: 34
Issue: 4
Pages: 1060-8
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18624920 | J:138852
First Author: Zhou J
Year: 2008
Journal: J Neurochem
Title: Complement C3 and C4 expression in C1q sufficient and deficient mouse models of Alzheimer's disease.
Volume: 106
Issue: 5
Pages: 2080-92
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17065436 | J:114690
First Author: Yin KJ
Year: 2006
Journal: J Neurosci
Title: Matrix metalloproteinases expressed by astrocytes mediate extracellular amyloid-beta peptide catabolism.
Volume: 26
Issue: 43
Pages: 10939-48
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26885753 | J:255079
First Author: Chaput D
Year: 2016
Journal: Oncotarget
Title: Potential role of PCTAIRE-2, PCTAIRE-3 and P-Histone H4 in amyloid precursor protein-dependent Alzheimer pathology.
Volume: 7
Issue: 8
Pages: 8481-97
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12402041 | J:80429
First Author: Tan J
Year: 2002
Journal: Nat Neurosci
Title: Role of CD40 ligand in amyloidosis in transgenic Alzheimer's mice.
Volume: 5
Issue: 12
Pages: 1288-93
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16730391 | J:121975
First Author: Costa DA
Year: 2007
Journal: Neurobiol Aging
Title: Enrichment improves cognition in AD mice by amyloid-related and unrelated mechanisms.
Volume: 28
Issue: 6
Pages: 831-44
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10613521 | J:59778
First Author: Umans L
Year: 1999
Journal: Neuroscience
Title: Lipoprotein receptor-related protein in brain and in cultured neurons of mice deficient in receptor-associated protein and transgenic for apolipoprotein E4 or amyloid precursor protein.
Volume: 94
Issue: 1
Pages: 315-21
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Publication
31931285 | J:296795
 
First Author: Li X
Year: 2020
Journal: EBioMedicine
Title: OCIAD1 contributes to neurodegeneration in Alzheimer's disease by inducing mitochondria dysfunction, neuronal vulnerability and synaptic damages.
Volume: 51
Pages: 102569
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Publication
23417057 | J:214142
First Author: Crowe SE
Year: 2014
Journal: Brain Struct Funct
Title: Spine pruning in 5xFAD mice starts on basal dendrites of layer 5 pyramidal neurons.
Volume: 219
Issue: 2
Pages: 571-80
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Publication
30323343 | J:282666
First Author: Ryu JK
Year: 2018
Journal: Nat Immunol
Title: Fibrin-targeting immunotherapy protects against neuroinflammation and neurodegeneration.
Volume: 19
Issue: 11
Pages: 1212-1223
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Publication
30737131 | J:277796
First Author: Merlini M
Year: 2019
Journal: Neuron
Title: Fibrinogen Induces Microglia-Mediated Spine Elimination and Cognitive Impairment in an Alzheimer's Disease Model.
Volume: 101
Issue: 6
Pages: 1099-1108.e6
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Publication
37667395 | J:340501
First Author: Jang J
Year: 2023
Journal: Acta Neuropathol Commun
Title: Abnormal accumulation of extracellular vesicles in hippocampal dystrophic axons and regulation by the primary cilia in Alzheimer's disease.
Volume: 11
Issue: 1
Pages: 142
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Publication
34258598 | J:348438
First Author: Tognatta R
Year: 2021
Journal: STAR Protoc
Title: In vivo two-photon microscopy protocol for imaging microglial responses and spine elimination at sites of fibrinogen deposition in mouse brain.
Volume: 2
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