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Search results 301 to 400 out of 437 for Tsc2

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Type Details Score
Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
21613414 | J:175260
First Author: Buller CL
Year: 2011
Journal: Am J Physiol Renal Physiol
Title: GLUT1 enhances mTOR activity independently of TSC2 and AMPK.
Volume: 301
Issue: 3
Pages: F588-96
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Publication
23818547 | J:202264
First Author: Lu J
Year: 2013
Journal: Blood
Title: Pim2 is required for maintaining multiple myeloma cell growth through modulating TSC2 phosphorylation.
Volume: 122
Issue: 9
Pages: 1610-20
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Publication
20160076 | J:158578
First Author: Alexander A
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: ATM signals to TSC2 in the cytoplasm to regulate mTORC1 in response to ROS.
Volume: 107
Issue: 9
Pages: 4153-8
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Publication
32781001 | J:301371
 
First Author: Iffland PH 2nd
Year: 2020
Journal: Exp Neurol
Title: Dynamic analysis of 4E-BP1 phosphorylation in neurons with Tsc2 or Depdc5 knockout.
Volume: 334
Pages: 113432
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Publication
23348097 | J:199040
First Author: Wang HL
Year: 2013
Journal: Biochim Biophys Acta
Title: XLID CUL4B mutants are defective in promoting TSC2 degradation and positively regulating mTOR signaling in neocortical neurons.
Volume: 1832
Issue: 4
Pages: 585-93
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Publication
10944454 | J:64047
First Author: Yamashita Y
Year: 2000
Journal: Biochem Biophys Res Commun
Title: Mapping and determination of the cDNA sequence of the Erc gene preferentially expressed in renal cell carcinoma in the Tsc2 gene mutant (Eker) rat model.
Volume: 275
Issue: 1
Pages: 134-40
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9831664 | J:52359
First Author: Imai K
Year: 1998
Journal: Gene
Title: Genomic structure and sequence of a human homologue (NTHL1/NTH1) of Escherichia coli endonuclease III with those of the adjacent parts of TSC2 and SLC9A3R2 genes.
Volume: 222
Issue: 2
Pages: 287-95
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Publication
9580671 | -
First Author: van Slegtenhorst M
Year: 1998
Journal: Hum Mol Genet
Title: Interaction between hamartin and tuberin, the TSC1 and TSC2 gene products.
Volume: 7
Issue: 6
Pages: 1053-7
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Publication
16464865 | -
First Author: Chong-Kopera H
Year: 2006
Journal: J Biol Chem
Title: TSC1 stabilizes TSC2 by inhibiting the interaction between TSC2 and the HERC1 ubiquitin ligase.
Volume: 281
Issue: 13
Pages: 8313-6
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Publication
12869586 | -
First Author: Inoki K
Year: 2003
Journal: Genes Dev
Title: Rheb GTPase is a direct target of TSC2 GAP activity and regulates mTOR signaling.
Volume: 17
Issue: 15
Pages: 1829-34
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Publication
15340059 | -
First Author: Li Y
Year: 2004
Journal: Mol Cell Biol
Title: Biochemical and functional characterizations of small GTPase Rheb and TSC2 GAP activity.
Volume: 24
Issue: 18
Pages: 7965-75
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Publication
24444419 | -
First Author: Ha JY
Year: 2014
Journal: J Neurochem
Title: Tnfaip8 l1/Oxi-β binds to FBXW5, increasing autophagy through activation of TSC2 in a Parkinson's disease model.
Volume: 129
Issue: 3
Pages: 527-38
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8806680 | -
First Author: Wienecke R
Year: 1996
Journal: Oncogene
Title: Co-localization of the TSC2 product tuberin with its target Rap1 in the Golgi apparatus.
Volume: 13
Issue: 5
Pages: 913-23
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18381890 | -
First Author: Hu J
Year: 2008
Journal: Genes Dev
Title: WD40 protein FBW5 promotes ubiquitination of tumor suppressor TSC2 by DDB1-CUL4-ROC1 ligase.
Volume: 22
Issue: 7
Pages: 866-71
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Publication
21827857 | J:179850
First Author: Chévere-Torres I
Year: 2012
Journal: Neurobiol Dis
Title: Impaired social interactions and motor learning skills in tuberous sclerosis complex model mice expressing a dominant/negative form of tuberin.
Volume: 45
Issue: 1
Pages: 156-64
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Publication
17077083 | -
First Author: Cao Y
Year: 2006
Journal: J Biol Chem
Title: Interaction of FoxO1 and TSC2 induces insulin resistance through activation of the mammalian target of rapamycin/p70 S6K pathway.
Volume: 281
Issue: 52
Pages: 40242-51
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Publication
15576369 | J:96943
First Author: Govindarajan B
Year: 2005
Journal: J Biol Chem
Title: Transgenic expression of dominant negative tuberin through a strong constitutive promoter results in a tissue-specific tuberous sclerosis phenotype in the skin and brain.
Volume: 280
Issue: 7
Pages: 5870-4
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19738049 | J:152687
First Author: Bhatia B
Year: 2009
Journal: Cancer Res
Title: Tuberous sclerosis complex suppression in cerebellar development and medulloblastoma: separate regulation of mammalian target of rapamycin activity and p27 Kip1 localization.
Volume: 69
Issue: 18
Pages: 7224-34
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12093749 | J:77767
First Author: Takao M
Year: 2002
Journal: EMBO J
Title: Novel nuclear and mitochondrial glycosylases revealed by disruption of the mouse Nth1 gene encoding an endonuclease III homolog for repair of thymine glycols.
Volume: 21
Issue: 13
Pages: 3486-93
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9233772 | -
First Author: Rosa JL
Year: 1997
Journal: Oncogene
Title: A giant protein that stimulates guanine nucleotide exchange on ARF1 and Rab proteins forms a cytosolic ternary complex with clathrin and Hsp70.
Volume: 15
Issue: 1
Pages: 1-6
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8861955 | -
First Author: Rosa JL
Year: 1996
Journal: EMBO J
Title: p619, a giant protein related to the chromosome condensation regulator RCC1, stimulates guanine nucleotide exchange on ARF1 and Rab proteins.
Volume: 15
Issue: 16
Pages: 4262-73
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Publication
25746226 | -
First Author: Bachiller S
Year: 2015
Journal: Cell Mol Life Sci
Title: The HERC1 E3 Ubiquitin Ligase is essential for normal development and for neurotransmission at the mouse neuromuscular junction.
Volume: 72
Issue: 15
Pages: 2961-71
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27147983 | -
 
First Author: Ruiz R
Year: 2016
Journal: Front Neuroanat
Title: HERC 1 Ubiquitin Ligase Mutation Affects Neocortical, CA3 Hippocampal and Spinal Cord Projection Neurons: An Ultrastructural Study.
Volume: 10
Pages: 42
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28323226 | -
First Author: Utine GE
Year: 2017
Journal: Eur J Med Genet
Title: HERC1 mutations in idiopathic intellectual disability.
Volume: 60
Issue: 5
Pages: 279-283
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27108999 | -
First Author: Aggarwal S
Year: 2016
Journal: Am J Med Genet A
Title: A splice site mutation in HERC1 leads to syndromic intellectual disability with macrocephaly and facial dysmorphism: Further delineation of the phenotypic spectrum.
Volume: 170
Issue: 7
Pages: 1868-73
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15728574 | -
First Author: Yu Y
Year: 2005
Journal: J Biol Chem
Title: Structural basis for the unique biological function of small GTPase RHEB.
Volume: 280
Issue: 17
Pages: 17093-100
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15854902 | -
First Author: Long X
Year: 2005
Journal: Curr Biol
Title: Rheb binds and regulates the mTOR kinase.
Volume: 15
Issue: 8
Pages: 702-13
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Publication
16098514 | -
First Author: Tee AR
Year: 2005
Journal: FEBS Lett
Title: Analysis of mTOR signaling by the small G-proteins, Rheb and RhebL1.
Volume: 579
Issue: 21
Pages: 4763-8
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29104218 | -
 
First Author: Tatebe H
Year: 2017
Journal: Biomolecules
Title: Evolutionary Conservation of the Components in the TOR Signaling Pathways.
Volume: 7
Issue: 4
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11884613 | J:75451
First Author: Shoshani T
Year: 2002
Journal: Mol Cell Biol
Title: Identification of a novel hypoxia-inducible factor 1-responsive gene, RTP801, involved in apoptosis.
Volume: 22
Issue: 7
Pages: 2283-93
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15632201 | -
First Author: Corradetti MN
Year: 2005
Journal: J Biol Chem
Title: The stress-inducted proteins RTP801 and RTP801L are negative regulators of the mammalian target of rapamycin pathway.
Volume: 280
Issue: 11
Pages: 9769-72
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16423342 | -
First Author: Scuderi A
Year: 2006
Journal: Dev Biol
Title: scylla and charybde, homologues of the human apoptotic gene RTP801, are required for head involution in Drosophila.
Volume: 291
Issue: 1
Pages: 110-22
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12271141 | -
First Author: Tee AR
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: Tuberous sclerosis complex-1 and -2 gene products function together to inhibit mammalian target of rapamycin (mTOR)-mediated downstream signaling.
Volume: 99
Issue: 21
Pages: 13571-6
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23439951 | J:198147
First Author: Kurbegovic A
Year: 2013
Journal: Hum Mol Genet
Title: Progressive development of polycystic kidney disease in the mouse model expressing Pkd1 extracellular domain.
Volume: 22
Issue: 12
Pages: 2361-75
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27488998 | J:281786
First Author: Kurbegovic A
Year: 2016
Journal: Am J Physiol Renal Physiol
Title: Acute kidney injury induces hallmarks of polycystic kidney disease.
Volume: 311
Issue: 4
Pages: F740-F751
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21439266 | J:171923
First Author: Uddin MN
Year: 2011
Journal: Biochem Biophys Res Commun
Title: Gadd34 induces autophagy through the suppression of the mTOR pathway during starvation.
Volume: 407
Issue: 4
Pages: 692-8
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8921388 | J:36020
First Author: Van Raay TJ
Year: 1996
Journal: Genomics
Title: A novel ribosomal protein L3-like gene (RPL3L) maps to the autosomal dominant polycystic kidney disease gene region.
Volume: 37
Issue: 2
Pages: 172-6
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16169463 | J:103552
First Author: Hay N
Year: 2005
Journal: Cancer Cell
Title: The Akt-mTOR tango and its relevance to cancer.
Volume: 8
Issue: 3
Pages: 179-83
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20466002 | J:161318
First Author: Arakawa-Takeuchi S
Year: 2010
Journal: FEBS Lett
Title: Mammalian target of rapamycin complex 1 signaling opposes the effects of anchorage loss, leading to activation of Cdk4 and Cdc6 stabilization.
Volume: 584
Issue: 13
Pages: 2779-85
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28814601 | J:251134
First Author: Sowell RT
Year: 2017
Journal: J Immunol
Title: IL-15 Complexes Induce Migration of Resting Memory CD8 T Cells into Mucosal Tissues.
Volume: 199
Issue: 7
Pages: 2536-2546
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16765995 | J:118080
First Author: Larsen E
Year: 2007
Journal: Mutat Res
Title: Organ and cell specificity of base excision repair mutants in mice.
Volume: 614
Issue: 1-2
Pages: 56-68
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17450122 | J:122765
First Author: Kovtun IV
Year: 2007
Journal: Nature
Title: OGG1 initiates age-dependent CAG trinucleotide expansion in somatic cells.
Volume: 447
Issue: 7143
Pages: 447-52
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20053665 | J:157952
First Author: Kurbegovic A
Year: 2010
Journal: Hum Mol Genet
Title: Pkd1 transgenic mice: adult model of polycystic kidney disease with extrarenal and renal phenotypes.
Volume: 19
Issue: 7
Pages: 1174-89
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18439900 | J:136666
First Author: Gwinn DM
Year: 2008
Journal: Mol Cell
Title: AMPK phosphorylation of raptor mediates a metabolic checkpoint.
Volume: 30
Issue: 2
Pages: 214-26
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29127155 | J:259136
First Author: Woodford MR
Year: 2017
Journal: EMBO J
Title: Tumor suppressor Tsc1 is a new Hsp90 co-chaperone that facilitates folding of kinase and non-kinase clients.
Volume: 36
Issue: 24
Pages: 3650-3665
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17141160 | J:137592
First Author: Guertin DA
Year: 2006
Journal: Dev Cell
Title: Ablation in mice of the mTORC components raptor, rictor, or mLST8 reveals that mTORC2 is required for signaling to Akt-FOXO and PKCalpha, but not S6K1.
Volume: 11
Issue: 6
Pages: 859-71
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23582324 | J:201276
First Author: Betschinger J
Year: 2013
Journal: Cell
Title: Exit from pluripotency is gated by intracellular redistribution of the bHLH transcription factor Tfe3.
Volume: 153
Issue: 2
Pages: 335-47
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16962653 | J:125618
First Author: Jacinto E
Year: 2006
Journal: Cell
Title: SIN1/MIP1 maintains rictor-mTOR complex integrity and regulates Akt phosphorylation and substrate specificity.
Volume: 127
Issue: 1
Pages: 125-37
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11011112 | J:70301
First Author: Majima S
Year: 2000
Journal: Jpn J Cancer Res
Title: A novel gene "Niban" upregulated in renal carcinogenesis: cloning by the cDNA-amplified fragment length polymorphism approach.
Volume: 91
Issue: 9
Pages: 869-74
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29133867 | J:255876
First Author: Gonçalves AF
Year: 2017
Journal: Nat Commun
Title: Evidence of renal angiomyolipoma neoplastic stem cells arising from renal epithelial cells.
Volume: 8
Issue: 1
Pages: 1466
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33271062 | J:302995
First Author: Najafov A
Year: 2021
Journal: Mol Cell
Title: RIPK1 Promotes Energy Sensing by the mTORC1 Pathway.
Volume: 81
Issue: 2
Pages: 370-385.e7
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33215753 | J:302301
First Author: Ko CJ
Year: 2021
Journal: EMBO J
Title: The E3 ubiquitin ligase Peli1 regulates the metabolic actions of mTORC1 to suppress antitumor T cell responses.
Volume: 40
Issue: 2
Pages: e104532
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32043969 | J:290269
   
First Author: Garg A
Year: 2020
Journal: Elife
Title: Etv transcription factors functionally diverge from their upstream FGF signaling in lens development.
Volume: 9
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35945201 | J:334140
First Author: Karalis V
Year: 2022
Journal: Nat Commun
Title: Raptor downregulation rescues neuronal phenotypes in mouse models of Tuberous Sclerosis Complex.
Volume: 13
Issue: 1
Pages: 4665
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35858542 | J:326953
First Author: Wu X
Year: 2022
Journal: Cell Rep
Title: Synaptic hyperexcitability of cytomegalic pyramidal neurons contributes to epileptogenesis in tuberous sclerosis complex.
Volume: 40
Issue: 3
Pages: 111085
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29281825 | J:277093
First Author: D'Gama AM
Year: 2017
Journal: Cell Rep
Title: Somatic Mutations Activating the mTOR Pathway in Dorsal Telencephalic Progenitors Cause a Continuum of Cortical Dysplasias.
Volume: 21
Issue: 13
Pages: 3754-3766
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35046889 | J:318753
 
First Author: Yamaguchi S
Year: 2021
Journal: Front Endocrinol (Lausanne)
Title: Adipocyte-Specific Inhibition of Mir221/222 Ameliorates Diet-Induced Obesity Through Targeting Ddit4.
Volume: 12
Pages: 750261
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35263141 | J:322291
First Author: Häusl AS
Year: 2022
Journal: Sci Adv
Title: Mediobasal hypothalamic FKBP51 acts as a molecular switch linking autophagy to whole-body metabolism.
Volume: 8
Issue: 10
Pages: eabi4797
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26977878 | J:231766
First Author: Goel S
Year: 2016
Journal: Cancer Cell
Title: Overcoming Therapeutic Resistance in HER2-Positive Breast Cancers with CDK4/6 Inhibitors.
Volume: 29
Issue: 3
Pages: 255-69
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17522300 | J:121858
First Author: Meikle L
Year: 2007
Journal: J Neurosci
Title: A mouse model of tuberous sclerosis: neuronal loss of Tsc1 causes dysplastic and ectopic neurons, reduced myelination, seizure activity, and limited survival.
Volume: 27
Issue: 21
Pages: 5546-58
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18664580 | J:139950
First Author: Mills JR
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: mTORC1 promotes survival through translational control of Mcl-1.
Volume: 105
Issue: 31
Pages: 10853-8
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21674478 | J:176815
First Author: Benhamron S
Year: 2011
Journal: Eur J Immunol
Title: Direct activation of mTOR in B lymphocytes confers impairment in B-cell maturation andloss of marginal zone B cells.
Volume: 41
Issue: 8
Pages: 2390-6
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19356717 | J:148167
First Author: Mori H
Year: 2009
Journal: Cell Metab
Title: Critical role for hypothalamic mTOR activity in energy balance.
Volume: 9
Issue: 4
Pages: 362-74
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16904612 | J:112705
First Author: Sodhi A
Year: 2006
Journal: Cancer Cell
Title: The TSC2/mTOR pathway drives endothelial cell transformation induced by the Kaposi's sarcoma-associated herpesvirus G protein-coupled receptor.
Volume: 10
Issue: 2
Pages: 133-43
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7972075 | J:29818
First Author: Yeung RS
Year: 1994
Journal: Proc Natl Acad Sci U S A
Title: Predisposition to renal carcinoma in the Eker rat is determined by germ-line mutation of the tuberous sclerosis 2 (TSC2) gene.
Volume: 91
Issue: 24
Pages: 11413-6
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7704028 | J:29986
First Author: Kobayashi T
Year: 1995
Journal: Nat Genet
Title: A germline insertion in the tuberous sclerosis (Tsc2) gene gives rise to the Eker rat model of dominantly inherited cancer.
Volume: 9
Issue: 1
Pages: 70-4
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8562486 | J:32686
First Author: Geist RT
Year: 1995
Journal: Cell Growth Differ
Title: The tuberous sclerosis 2 gene is expressed at high levels in the cerebellum and developing spinal cord.
Volume: 6
Issue: 11
Pages: 1477-83
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9250859 | J:42178
First Author: Kobayashi T
Year: 1997
Journal: Mamm Genome
Title: Identification of a leader exon and a core promoter for the rat tuberous sclerosis 2 (Tsc2) gene and structural comparison with the human homolog.
Volume: 8
Issue: 8
Pages: 554-8
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16996505 | J:114651
First Author: Wan M
Year: 2006
Journal: FEBS Lett
Title: Muscle atrophy in transgenic mice expressing a human TSC1 transgene.
Volume: 580
Issue: 24
Pages: 5621-7
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Publication
24486219 | J:216638
First Author: Faubert B
Year: 2015
Journal: Cancer Lett
Title: The AMP-activated protein kinase (AMPK) and cancer: many faces of a metabolic regulator.
Volume: 356
Issue: 2 Pt A
Pages: 165-70
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28894028 | J:253016
     
First Author: Bartolomé A
Year: 2017
Journal: Mol Cell Biol
Title: MTORC1 Regulates both General Autophagy and Mitophagy Induction after Oxidative Phosphorylation Uncoupling.
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Publication
25081057 | J:272428
 
First Author: Lozovaya N
Year: 2014
Journal: Nat Commun
Title: Selective suppression of excessive GluN2C expression rescues early epilepsy in a tuberous sclerosis murine model.
Volume: 5
Pages: 4563
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30988000 | J:276866
 
First Author: Byun JK
Year: 2019
Journal: EMBO Rep
Title: Oncogenic KRAS signaling activates mTORC1 through COUP-TFII-mediated lactate production.
Volume: 20
Issue: 6
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32294430 | J:306324
First Author: Romero-Pozuelo J
Year: 2020
Journal: Cell Rep
Title: Cdk4 and Cdk6 Couple the Cell-Cycle Machinery to Cell Growth via mTORC1.
Volume: 31
Issue: 2
Pages: 107504
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9045618 | -
First Author: Xiao GH
Year: 1997
Journal: J Biol Chem
Title: The tuberous sclerosis 2 gene product, tuberin, functions as a Rab5 GTPase activating protein (GAP) in modulating endocytosis.
Volume: 272
Issue: 10
Pages: 6097-100
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24958103 | J:224268
First Author: Kurbegovic A
Year: 2014
Journal: Mol Cell Biol
Title: Novel functional complexity of polycystin-1 by GPS cleavage in vivo: role in polycystic kidney disease.
Volume: 34
Issue: 17
Pages: 3341-53
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15988001 | J:99368
First Author: Sofer A
Year: 2005
Journal: Mol Cell Biol
Title: Regulation of mTOR and cell growth in response to energy stress by REDD1.
Volume: 25
Issue: 14
Pages: 5834-45
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33184932 | J:309557
First Author: Wei Z
Year: 2021
Journal: FASEB J
Title: Death-associated protein kinase 1 (DAPK1) controls CD8+ T cell activation, trafficking, and antitumor activity.
Volume: 35
Issue: 1
Pages: e21138
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25315696 | J:218407
First Author: Britto FA
Year: 2014
Journal: Am J Physiol Endocrinol Metab
Title: REDD1 deletion prevents dexamethasone-induced skeletal muscle atrophy.
Volume: 307
Issue: 11
Pages: E983-93
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26487002 | J:229689
First Author: Steiner JL
Year: 2015
Journal: Am J Physiol Endocrinol Metab
Title: Disruption of REDD1 gene ameliorates sepsis-induced decrease in mTORC1 signaling but has divergent effects on proteolytic signaling in skeletal muscle.
Volume: 309
Issue: 12
Pages: E981-94
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26449264 | J:226834
First Author: Jones I
Year: 2015
Journal: Dis Model Mech
Title: A novel mouse model of tuberous sclerosis complex (TSC): eye-specific Tsc1-ablation disrupts visual-pathway development.
Volume: 8
Issue: 12
Pages: 1517-29
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23197407 | J:232309
First Author: Wang RH
Year: 2013
Journal: EMBO Mol Med
Title: The orphan receptor TR3 participates in angiotensin II-induced cardiac hypertrophy by controlling mTOR signalling.
Volume: 5
Issue: 1
Pages: 137-48
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Publication
15888477 | J:99796
First Author: Wilson C
Year: 2005
Journal: Hum Mol Genet
Title: A mouse model of tuberous sclerosis 1 showing background specific early post-natal mortality and metastatic renal cell carcinoma.
Volume: 14
Issue: 13
Pages: 1839-50
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23049074 | J:191137
First Author: Carson RP
Year: 2013
Journal: Hum Mol Genet
Title: Deletion of Rictor in neural progenitor cells reveals contributions of mTORC2 signaling to tuberous sclerosis complex.
Volume: 22
Issue: 1
Pages: 140-52
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Publication
22674026 | J:188431
First Author: Armour EA
Year: 2012
Journal: Am J Physiol Renal Physiol
Title: Cystogenesis and elongated primary cilia in Tsc1-deficient distal convoluted tubules.
Volume: 303
Issue: 4
Pages: F584-92
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Publication
26296882 | J:225965
First Author: Hu Z
Year: 2015
Journal: J Biol Chem
Title: Brain-expressed X-linked 2 Is Pivotal for Hyperactive Mechanistic Target of Rapamycin (mTOR)-mediated Tumorigenesis.
Volume: 290
Issue: 42
Pages: 25756-65
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Publication
19692352 | J:153717
First Author: Zhou J
Year: 2009
Journal: Hum Mol Genet
Title: Loss of Tsc1, but not Pten, in renal tubular cells causes polycystic kidney disease by activating mTORC1.
Volume: 18
Issue: 22
Pages: 4428-41
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Publication
19966866 | J:160400
First Author: Liang MC
Year: 2010
Journal: Oncogene
Title: TSC1 loss synergizes with KRAS activation in lung cancer development in the mouse and confers rapamycin sensitivity.
Volume: 29
Issue: 11
Pages: 1588-97
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Publication
31599935 | J:281732
First Author: Jin X
Year: 2019
Journal: Endocrinology
Title: Cartilage Ablation of Sirt1 Causes Inhibition of Growth Plate Chondrogenesis by Hyperactivation of mTORC1 Signaling.
Volume: 160
Issue: 12
Pages: 3001-3017
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Publication
21212099 | J:169239
First Author: Malhowski AJ
Year: 2011
Journal: Hum Mol Genet
Title: Smooth muscle protein-22-mediated deletion of Tsc1 results in cardiac hypertrophy that is mTORC1-mediated and reversed by rapamycin.
Volume: 20
Issue: 7
Pages: 1290-305
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Publication
30760873 | J:305028
First Author: Li C
Year: 2019
Journal: Cell Death Differ
Title: mTOR-dependent upregulation of xCT blocks melanin synthesis and promotes tumorigenesis.
Volume: 26
Issue: 10
Pages: 2015-2028
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Publication
21403402 | J:172004
First Author: Feliciano DM
Year: 2011
Journal: J Clin Invest
Title: Single-cell Tsc1 knockout during corticogenesis generates tuber-like lesions and reduces seizure threshold in mice.
Volume: 121
Issue: 4
Pages: 1596-607
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Publication
19420259 | J:148479
First Author: Di Nardo A
Year: 2009
Journal: J Neurosci
Title: Tuberous sclerosis complex activity is required to control neuronal stress responses in an mTOR-dependent manner.
Volume: 29
Issue: 18
Pages: 5926-37
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Publication
18495876 | J:136366
First Author: Meikle L
Year: 2008
Journal: J Neurosci
Title: Response of a neuronal model of tuberous sclerosis to mammalian target of rapamycin (mTOR) inhibitors: effects on mTORC1 and Akt signaling lead to improved survival and function.
Volume: 28
Issue: 21
Pages: 5422-32
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Publication
24599401 | J:210659
First Author: Di Nardo A
Year: 2014
Journal: Hum Mol Genet
Title: Neuronal Tsc1/2 complex controls autophagy through AMPK-dependent regulation of ULK1.
Volume: 23
Issue: 14
Pages: 3865-74
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Publication
23696872 | J:221022
First Author: Prabhakar S
Year: 2013
Journal: PLoS One
Title: Stochastic model of Tsc1 lesions in mouse brain.
Volume: 8
Issue: 5
Pages: e64224
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Publication
15601645 | J:96138
First Author: Meikle L
Year: 2005
Journal: Hum Mol Genet
Title: A mouse model of cardiac rhabdomyoma generated by loss of Tsc1 in ventricular myocytes.
Volume: 14
Issue: 3
Pages: 429-35
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Publication
33071758 | J:313985
 
First Author: Wundrach D
Year: 2020
Journal: Front Mol Neurosci
Title: A Human TSC1 Variant Screening Platform in Gabaergic Cortical Interneurons for Genotype to Phenotype Assessments.
Volume: 13
Pages: 573409
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Publication
28933629 | J:337049
First Author: Kim SH
Year: 2017
Journal: Autophagy
Title: Ezetimibe ameliorates steatohepatitis via AMP activated protein kinase-TFEB-mediated activation of autophagy and NLRP3 inflammasome inhibition.
Volume: 13
Issue: 10
Pages: 1767-1781
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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