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Search results 1 to 98 out of 98 for Cycs

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Category: Publication
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Type Details Score
Publication
19075019 | J:147780
First Author: Vempati UD
Year: 2009
Journal: J Biol Chem
Title: Lack of cytochrome c in mouse fibroblasts disrupts assembly/stability of respiratory complexes I and IV.
Volume: 284
Issue: 7
Pages: 4383-91
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Publication
30191381 | J:285935
First Author: Pinto M
Year: 2019
Journal: Mol Neurobiol
Title: Ablation of Cytochrome c in Adult Forebrain Neurons Impairs Oxidative Phosphorylation Without Detectable Apoptosis.
Volume: 56
Issue: 5
Pages: 3722-3735
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Publication
17210651 | J:118859
First Author: Vempati UD
Year: 2007
Journal: Mol Cell Biol
Title: Role of cytochrome C in apoptosis: increased sensitivity to tumor necrosis factor alpha is associated with respiratory defects but not with lack of cytochrome C release.
Volume: 27
Issue: 5
Pages: 1771-83
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Publication
24329121 | J:210495
First Author: Josephs TM
Year: 2014
Journal: Biochem J
Title: Enhancing the peroxidase activity of cytochrome c by mutation of residue 41: implications for the peroxidase mechanism and cytochrome c release.
Volume: 458
Issue: 2
Pages: 259-65
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Publication
26086723 | J:237795
First Author: Josephs TM
Year: 2015
Journal: PLoS One
Title: Interspecies Variation in the Functional Consequences of Mutation of Cytochrome c.
Volume: 10
Issue: 6
Pages: e0130292
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Publication
16054088 | J:129813
First Author: Mansfield KD
Year: 2005
Journal: Cell Metab
Title: Mitochondrial dysfunction resulting from loss of cytochrome c impairs cellular oxygen sensing and hypoxic HIF-alpha activation.
Volume: 1
Issue: 6
Pages: 393-9
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Publication
18550520 | J:139891
First Author: Kanungo AK
Year: 2008
Journal: J Biol Chem
Title: Inhibition of apoptosome activation protects injured motor neurons from cell death.
Volume: 283
Issue: 32
Pages: 22105-12
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Publication
3032216 | J:38097
First Author: Kim IC
Year: 1986
Journal: Biochem Cell Biol
Title: Antigenic analysis of testicular cytochromes c using monoclonal antibodies.
Volume: 64
Issue: 12
Pages: 1211-7
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Publication
8383125 | J:4083
First Author: Hake LE
Year: 1993
Journal: J Biol Chem
Title: Utilization of an alternative transcription initiation site of somatic cytochrome c in the mouse produces a testis-specific cytochrome c mRNA.
Volume: 268
Issue: 7
Pages: 4788-97
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Publication
15933725 | J:111870
First Author: Goldstein JC
Year: 2005
Journal: Cell Death Differ
Title: Cytochrome c is released in a single step during apoptosis.
Volume: 12
Issue: 5
Pages: 453-62
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Publication
18004876 | J:128533
First Author: Kapralov AA
Year: 2007
Journal: Biochemistry
Title: The hierarchy of structural transitions induced in cytochrome c by anionic phospholipids determines its peroxidase activation and selective peroxidation during apoptosis in cells.
Volume: 46
Issue: 49
Pages: 14232-44
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Publication
19455142 | J:151099
First Author: Yang G
Year: 2009
Journal: Br J Cancer
Title: Mitochondrial dysfunction resulting from loss of cytochrome c impairs radiation-induced bystander effect.
Volume: 100
Issue: 12
Pages: 1912-6
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Publication
11986672 | J:156069
First Author: Ruitenberg M
Year: 2002
Journal: Nature
Title: Reduction of cytochrome c oxidase by a second electron leads to proton translocation.
Volume: 417
Issue: 6884
Pages: 99-102
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Publication
2987801 | J:38101
First Author: Limbach KJ
Year: 1985
Journal: Nucleic Acids Res
Title: Characterization of a mouse somatic cytochrome c gene and three cytochrome c pseudogenes.
Volume: 13
Issue: 2
Pages: 617-30
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Publication
2834389 | J:9150
First Author: Virbasius JV
Year: 1988
Journal: J Biol Chem
Title: Structure and expression of rodent genes encoding the testis-specific cytochrome c. Differences in gene structure and evolution between somatic and testicular variants.
Volume: 263
Issue: 14
Pages: 6791-6
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Publication
10830166 | J:62276
First Author: Li K
Year: 2000
Journal: Cell
Title: Cytochrome c deficiency causes embryonic lethality and attenuates stress-induced apoptosis.
Volume: 101
Issue: 4
Pages: 389-99
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Publication
15907471 | J:98949
First Author: Hao Z
Year: 2005
Journal: Cell
Title: Specific ablation of the apoptotic functions of cytochrome C reveals a differential requirement for cytochrome C and Apaf-1 in apoptosis.
Volume: 121
Issue: 4
Pages: 579-91
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Publication
16757556 | J:111056
First Author: Liu Z
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Remarkably high activities of testicular cytochrome c in destroying reactive oxygen species and in triggering apoptosis.
Volume: 103
Issue: 24
Pages: 8965-70
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Publication
1964409 | J:22956
First Author: Hake LE
Year: 1990
Journal: Development
Title: Changes in mRNA length accompany translational regulation of the somatic and testis-specific cytochrome c genes during spermatogenesis in the mouse.
Volume: 110
Issue: 1
Pages: 249-57
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Publication
7984407 | J:21719
First Author: Yiu GK
Year: 1994
Journal: Nucleic Acids Res
Title: Heterogeneity in the 5' untranslated region of mouse cytochrome cT mRNAs leads to altered translational status of the mRNAs.
Volume: 22
Issue: 22
Pages: 4599-606
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Publication
23395375 | J:197848
First Author: van Spronsen M
Year: 2013
Journal: Neuron
Title: TRAK/Milton motor-adaptor proteins steer mitochondrial trafficking to axons and dendrites.
Volume: 77
Issue: 3
Pages: 485-502
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Publication
11836241 | J:76058
First Author: Degenhardt K
Year: 2002
Journal: J Biol Chem
Title: Bax and Bak independently promote cytochrome C release from mitochondria.
Volume: 277
Issue: 16
Pages: 14127-34
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Publication
22442658 | J:224209
First Author: Ferrer PE
Year: 2012
Journal: PLoS One
Title: Translocation of a Bak C-terminus mutant from cytosol to mitochondria to mediate cytochrome C release: implications for Bak and Bax apoptotic function.
Volume: 7
Issue: 3
Pages: e31510
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9560217 | J:47609
First Author: Jürgensmeier JM
Year: 1998
Journal: Proc Natl Acad Sci U S A
Title: Bax directly induces release of cytochrome c from isolated mitochondria.
Volume: 95
Issue: 9
Pages: 4997-5002
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10206961 | J:320091
First Author: Zou H
Year: 1999
Journal: J Biol Chem
Title: An APAF-1.cytochrome c multimeric complex is a functional apoptosome that activates procaspase-9.
Volume: 274
Issue: 17
Pages: 11549-56
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11864976 | J:76519
First Author: Karpinich NO
Year: 2002
Journal: J Biol Chem
Title: The course of etoposide-induced apoptosis from damage to DNA and p53 activation to mitochondrial release of cytochrome c.
Volume: 277
Issue: 19
Pages: 16547-52
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19875445 | J:161686
First Author: Owens TW
Year: 2010
Journal: J Biol Chem
Title: Role for X-linked Inhibitor of apoptosis protein upstream of mitochondrial permeabilization.
Volume: 285
Issue: 2
Pages: 1081-8
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Publication
17571083 | J:141360
First Author: Tan Z
Year: 2007
Journal: Cell Death Differ
Title: Mutant ubiquitin found in Alzheimer's disease causes neuritic beading of mitochondria in association with neuronal degeneration.
Volume: 14
Issue: 10
Pages: 1721-32
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Publication
8034327 | J:17608
First Author: Hake LE
Year: 1994
Journal: Genomics
Title: The genes encoding the somatic and testis-specific isotypes of the mouse cytochrome c genes map to paralogous regions of chromosomes 6 and 2.
Volume: 20
Issue: 3
Pages: 503-5
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Publication
15271982 | J:93333
First Author: Sakai T
Year: 2004
Journal: J Biol Chem
Title: Nucling recruits Apaf-1/pro-caspase-9 complex for the induction of stress-induced apoptosis.
Volume: 279
Issue: 39
Pages: 41131-40
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Publication
26178919 | J:223645
First Author: Hashimoto M
Year: 2015
Journal: Dev Growth Differ
Title: Nepro is localized in the nucleolus and essential for preimplantation development in mice.
Volume: 57
Issue: 7
Pages: 529-38
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Publication
14657025 | J:87073
First Author: Rajpal A
Year: 2003
Journal: EMBO J
Title: Transcriptional activation of known and novel apoptotic pathways by Nur77 orphan steroid receptor.
Volume: 22
Issue: 24
Pages: 6526-36
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Publication
21352494 | J:188100
First Author: Zhang W
Year: 2011
Journal: FEBS J
Title: Expression of CYP2E1 increases oxidative stress and induces apoptosis of cardiomyocytes in transgenic mice.
Volume: 278
Issue: 9
Pages: 1484-92
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Publication
16469926 | J:105496
First Author: Lakhani SA
Year: 2006
Journal: Science
Title: Caspases 3 and 7: key mediators of mitochondrial events of apoptosis.
Volume: 311
Issue: 5762
Pages: 847-51
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Publication
36459881 | J:332399
 
First Author: Sato K
Year: 2023
Journal: Biochem Biophys Res Commun
Title: Central nervous system specific high molecular weight ALS2/alsin homophilic complex is enriched in mouse brain synaptosomes.
Volume: 638
Pages: 168-175
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Publication
31001720 | J:284778
First Author: Huebner AK
Year: 2019
Journal: J Assoc Res Otolaryngol
Title: Early Hearing Loss upon Disruption of Slc4a10 in C57BL/6 Mice.
Volume: 20
Issue: 3
Pages: 233-245
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Publication
14623868 | J:86711
First Author: Potts PR
Year: 2003
Journal: J Cell Biol
Title: Critical function of endogenous XIAP in regulating caspase activation during sympathetic neuronal apoptosis.
Volume: 163
Issue: 4
Pages: 789-99
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12142566 | J:167678
First Author: Shibata M
Year: 2002
Journal: J Cereb Blood Flow Metab
Title: Temporal profiles of the subcellular localization of Bim, a BH3-only protein, during middle cerebral artery occlusion in mice.
Volume: 22
Issue: 7
Pages: 810-20
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7774957 | J:22835
First Author: Kozak CA
Year: 1995
Journal: Genomics
Title: Genetic mapping in human and mouse of the locus encoding TRBP, a protein that binds the TAR region of the human immunodeficiency virus (HIV-1).
Volume: 25
Issue: 1
Pages: 66-72
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22343714 | J:204631
First Author: Wilfling F
Year: 2012
Journal: Cell Death Differ
Title: BH3-only proteins are tail-anchored in the outer mitochondrial membrane and can initiate the activation of Bax.
Volume: 19
Issue: 8
Pages: 1328-36
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30004576 | J:266346
First Author: Yamada S
Year: 2018
Journal: J Comp Neurol
Title: Expression profile of the STAND protein Nwd1 in the developing and mature mouse central nervous system.
Volume: 526
Issue: 13
Pages: 2099-2114
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Publication
22357545 | J:185833
First Author: Fernandes R
Year: 2012
Journal: Biol Reprod
Title: NLRP5 mediates mitochondrial function in mouse oocytes and embryos.
Volume: 86
Issue: 5
Pages: 138, 1-10
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Publication
24632563 | J:210320
 
First Author: Josefsson EC
Year: 2014
Journal: Nat Commun
Title: Platelet production proceeds independently of the intrinsic and extrinsic apoptosis pathways.
Volume: 5
Pages: 3455
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Publication
20671748 | J:186336
First Author: Cleland MM
Year: 2011
Journal: Cell Death Differ
Title: Bcl-2 family interaction with the mitochondrial morphogenesis machinery.
Volume: 18
Issue: 2
Pages: 235-47
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31601784 | J:282096
First Author: Duan Y
Year: 2019
Journal: Cell Death Dis
Title: Heat shock protein 60 regulates yolk sac erythropoiesis in mice.
Volume: 10
Issue: 10
Pages: 766
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Publication
16103131 | J:101747
First Author: Diaz F
Year: 2005
Journal: Hum Mol Genet
Title: Mice lacking COX10 in skeletal muscle recapitulate the phenotype of progressive mitochondrial myopathies associated with cytochrome c oxidase deficiency.
Volume: 14
Issue: 18
Pages: 2737-48
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Publication
22351927 | J:181685
First Author: Bakkar N
Year: 2012
Journal: J Cell Biol
Title: IKKα and alternative NF-κB regulate PGC-1β to promote oxidative muscle metabolism.
Volume: 196
Issue: 4
Pages: 497-511
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25662615 | J:316550
First Author: Himes KP
Year: 2015
Journal: Placenta
Title: Loss of inherited genomic imprints in mice leads to severe disruption in placental lipid metabolism.
Volume: 36
Issue: 4
Pages: 389-96
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Publication
35238380 | J:324530
 
First Author: Fonseca TL
Year: 2022
Journal: Endocrinology
Title: Inactivation of Type 3 Deiodinase Results in Life-long Changes in the Brown Adipose Tissue Transcriptome in the Male Mouse.
Volume: 163
Issue: 5
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Publication
26403541 | J:227218
 
First Author: Sharma P
Year: 2015
Journal: Nat Commun
Title: Evolutionarily conserved intercalated disc protein Tmem65 regulates cardiac conduction and connexin 43 function.
Volume: 6
Pages: 8391
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18719582 | J:138823
First Author: Seale P
Year: 2008
Journal: Nature
Title: PRDM16 controls a brown fat/skeletal muscle switch.
Volume: 454
Issue: 7207
Pages: 961-7
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18628400 | J:137598
First Author: Lai L
Year: 2008
Journal: Genes Dev
Title: Transcriptional coactivators PGC-1alpha and PGC-lbeta control overlapping programs required for perinatal maturation of the heart.
Volume: 22
Issue: 14
Pages: 1948-61
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26963625 | J:232408
First Author: Van De Pette M
Year: 2016
Journal: PLoS Genet
Title: Cdkn1c Boosts the Development of Brown Adipose Tissue in a Murine Model of Silver Russell Syndrome.
Volume: 12
Issue: 3
Pages: e1005916
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7558022 | J:27401
First Author: Miyazaki S
Year: 1995
Journal: Genomics
Title: The chromosomal location of the mouse mammary tumor gene Int6 and related pseudogenes in the mouse genome.
Volume: 27
Issue: 3
Pages: 420-4
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33846639 | J:308105
First Author: Angueira AR
Year: 2021
Journal: Nat Metab
Title: Defining the lineage of thermogenic perivascular adipose tissue.
Volume: 3
Issue: 4
Pages: 469-484
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27106802 | J:253948
 
First Author: Magarin M
Year: 2016
Journal: J Mol Cell Cardiol
Title: Embryonic cardiomyocytes can orchestrate various cell protective mechanisms to survive mitochondrial stress.
Volume: 97
Pages: 1-14
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23499423 | J:198125
First Author: Rajakumari S
Year: 2013
Journal: Cell Metab
Title: EBF2 determines and maintains brown adipocyte identity.
Volume: 17
Issue: 4
Pages: 562-74
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Publication
25332179 | J:244948
First Author: Wang DY
Year: 2014
Journal: J Am Heart Assoc
Title: Endoplasmic reticulum resident protein 44 (ERp44) deficiency in mice and zebrafish leads to cardiac developmental and functional defects.
Volume: 3
Issue: 5
Pages: e001018
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22904094 | J:212629
First Author: Papanicolaou KN
Year: 2012
Journal: Circ Res
Title: Mitofusins 1 and 2 are essential for postnatal metabolic remodeling in heart.
Volume: 111
Issue: 8
Pages: 1012-26
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17276355 | J:129766
First Author: Sano M
Year: 2007
Journal: Cell Metab
Title: Ménage-à-trois 1 is critical for the transcriptional function of PPARgamma coactivator 1.
Volume: 5
Issue: 2
Pages: 129-42
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24703692 | J:213153
First Author: Harms MJ
Year: 2014
Journal: Cell Metab
Title: Prdm16 is required for the maintenance of brown adipocyte identity and function in adult mice.
Volume: 19
Issue: 4
Pages: 593-604
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23236519 | J:195548
First Author: Brody MJ
Year: 2012
Journal: PLoS One
Title: Ablation of the cardiac-specific gene leucine-rich repeat containing 10 (Lrrc10) results in dilated cardiomyopathy.
Volume: 7
Issue: 12
Pages: e51621
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27166947 | J:235368
First Author: Gómez-Del Arco P
Year: 2016
Journal: Cell Metab
Title: The Chromatin Remodeling Complex Chd4/NuRD Controls Striated Muscle Identity and Metabolic Homeostasis.
Volume: 23
Issue: 5
Pages: 881-92
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17634366 | J:145263
First Author: Werner HB
Year: 2007
Journal: J Neurosci
Title: Proteolipid protein is required for transport of sirtuin 2 into CNS myelin.
Volume: 27
Issue: 29
Pages: 7717-30
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Publication
- | J:193309
       
First Author: Mouse Genome Informatics Scientfic Curators
Year: 2013
Title: Curated associations of genes in MGI and UniProt sequence records
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Publication
14651853 | J:86816
First Author: Mootha VK
Year: 2003
Journal: Cell
Title: Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria.
Volume: 115
Issue: 5
Pages: 629-40
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18614015 | J:151002
First Author: Pagliarini DJ
Year: 2008
Journal: Cell
Title: A mitochondrial protein compendium elucidates complex I disease biology.
Volume: 134
Issue: 1
Pages: 112-23
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- | J:342607
       
First Author: Birgit Meldal and Sandra Orchard (1). (1) European Bioinformatics Institute (EBI), Hinxton, Cambridgeshire, United Kingdom
Year: 2023
Title: Manual transfer of experimentally-verified manual GO annotation data to homologous complexes by curator judgment of sequence, composition and function similarity
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- | J:171409
     
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
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Publication
- | J:72247
       
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
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- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
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First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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First Author: Narisawa S
Year: 2002
Journal: Mol Cell Biol
Title: Testis-specific cytochrome c-null mice produce functional sperm but undergo early testicular atrophy.
Volume: 22
Issue: 15
Pages: 5554-62
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First Author: Onnis A
Year: 2018
Journal: Autophagy
Title: The pro-oxidant adaptor p66SHC promotes B cell mitophagy by disrupting mitochondrial integrity and recruiting LC3-II.
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Issue: 12
Pages: 2117-2138
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First Author: Krois CR
Year: 2019
Journal: Cell Mol Life Sci
Title: RDH1 suppresses adiposity by promoting brown adipose adaptation to fasting and re-feeding.
Volume: 76
Issue: 12
Pages: 2425-2447
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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