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Search results 1 to 100 out of 478 for Flt3

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Category: Publication
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Type Details Score
Publication
17124058 | -
   
First Author: Small D
Year: 2006
Journal: Hematology Am Soc Hematol Educ Program
Title: FLT3 mutations: biology and treatment.
Pages: 178-84
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Publication
21262971 | -
First Author: Arora D
Year: 2011
Journal: J Biol Chem
Title: Protein-tyrosine phosphatase DEP-1 controls receptor tyrosine kinase FLT3 signaling.
Volume: 286
Issue: 13
Pages: 10918-29
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Publication
23246379 | -
First Author: Kazi JU
Year: 2013
Journal: Mol Oncol
Title: FLT3 signals via the adapter protein Grb10 and overexpression of Grb10 leads to aberrant cell proliferation in acute myeloid leukemia.
Volume: 7
Issue: 3
Pages: 402-18
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Publication
21516120 | J:177101
First Author: Zheng R
Year: 2011
Journal: Oncogene
Title: Further activation of FLT3 mutants by FLT3 ligand.
Volume: 30
Issue: 38
Pages: 4004-14
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Publication
18469816 | J:136209
First Author: Waskow C
Year: 2008
Journal: Nat Immunol
Title: The receptor tyrosine kinase Flt3 is required for dendritic cell development in peripheral lymphoid tissues.
Volume: 9
Issue: 6
Pages: 676-83
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Publication
20457904 | J:159599
First Author: Eidenschenk C
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Flt3 permits survival during infection by rendering dendritic cells competent to activate NK cells.
Volume: 107
Issue: 21
Pages: 9759-64
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Publication
10409713 | J:56367
First Author: Wolf I
Year: 1999
Journal: J Biol Chem
Title: Fiz1, a novel zinc finger protein interacting with the receptor tyrosine kinase Flt3.
Volume: 274
Issue: 30
Pages: 21478-84
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Publication
21628405 | J:176945
First Author: Buza-Vidas N
Year: 2011
Journal: Blood
Title: FLT3 expression initiates in fully multipotent mouse hematopoietic progenitor cells.
Volume: 118
Issue: 6
Pages: 1544-8
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Publication
1656368 | J:1614
First Author: Rosnet O
Year: 1991
Journal: Oncogene
Title: Murine Flt3, a gene encoding a novel tyrosine kinase receptor of the PDGFR/CSF1R family.
Volume: 6
Issue: 9
Pages: 1641-50
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Publication
27458164 | J:268117
First Author: Moharram SA
Year: 2016
Journal: Oncotarget
Title: Src-like adaptor protein 2 (SLAP2) binds to and inhibits FLT3 signaling.
Volume: 7
Issue: 36
Pages: 57770-57782
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Publication
8384358 | J:140548
First Author: Maroc N
Year: 1993
Journal: Oncogene
Title: Biochemical characterization and analysis of the transforming potential of the FLT3/FLK2 receptor tyrosine kinase.
Volume: 8
Issue: 4
Pages: 909-18
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Publication
1648448 | J:11299
First Author: Matthews W
Year: 1991
Journal: Cell
Title: A receptor tyrosine kinase specific to hematopoietic stem and progenitor cell-enriched populations.
Volume: 65
Issue: 7
Pages: 1143-52
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Publication
7621074 | J:27238
First Author: Mackarehtschian K
Year: 1995
Journal: Immunity
Title: Targeted disruption of the flk2/flt3 gene leads to deficiencies in primitive hematopoietic progenitors.
Volume: 3
Issue: 1
Pages: 147-61
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Publication
7917833 | J:19248
First Author: Ito A
Year: 1993
Journal: J Mol Neurosci
Title: Developmental expression of flt3 mRNA in the mouse brain.
Volume: 4
Issue: 4
Pages: 235-43
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Publication
19286519 | J:147362
First Author: Liu K
Year: 2009
Journal: Science
Title: In vivo analysis of dendritic cell development and homeostasis.
Volume: 324
Issue: 5925
Pages: 392-7
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Publication
30596405 | J:295115
First Author: Zriwil A
Year: 2018
Journal: Br J Haematol
Title: Direct role of FLT3 in regulation of early lymphoid progenitors.
Volume: 183
Issue: 4
Pages: 588-600
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Publication
22078798 | J:178831
First Author: Choi JH
Year: 2011
Journal: Immunity
Title: Flt3 signaling-dependent dendritic cells protect against atherosclerosis.
Volume: 35
Issue: 5
Pages: 819-31
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Publication
25234168 | J:219685
First Author: Kato T
Year: 2015
Journal: Leukemia
Title: Hes1 suppresses acute myeloid leukemia development through FLT3 repression.
Volume: 29
Issue: 3
Pages: 576-85
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Publication
26062848 | J:234072
First Author: Lim Y
Year: 2015
Journal: Sci Transl Med
Title: Integration of Hedgehog and mutant FLT3 signaling in myeloid leukemia.
Volume: 7
Issue: 291
Pages: 291ra96
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Publication
18299401 | J:133083
First Author: Kenins L
Year: 2008
Journal: J Exp Med
Title: Intrathymic expression of Flt3 ligand enhances thymic recovery after irradiation.
Volume: 205
Issue: 3
Pages: 523-31
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Publication
7622010 | J:26783
First Author: deLapeyrière O
Year: 1995
Journal: Differentiation
Title: Expression of Flt3 tyrosine kinase receptor gene in mouse hematopoietic and nervous tissues.
Volume: 58
Issue: 5
Pages: 351-9
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Publication
20393130 | J:161537
First Author: Böiers C
Year: 2010
Journal: Blood
Title: Expression and role of FLT3 in regulation of the earliest stage of normal granulocyte-monocyte progenitor development.
Volume: 115
Issue: 24
Pages: 5061-8
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Publication
16618805 | J:108330
First Author: Holmes ML
Year: 2006
Journal: Genes Dev
Title: Repression of Flt3 by Pax5 is crucial for B-cell lineage commitment.
Volume: 20
Issue: 8
Pages: 933-8
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Publication
26411368 | J:234309
First Author: Chen Y
Year: 2016
Journal: Oncogene
Title: Identification of an orally available compound with potent and broad FLT3 inhibition activity.
Volume: 35
Issue: 23
Pages: 2971-8
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Publication
23759524 | J:238831
First Author: Bailey EJ
Year: 2013
Journal: Comp Med
Title: Effect of FLT3 ligand on survival and disease phenotype in murine models harboring a FLT3 internal tandem duplication mutation.
Volume: 63
Issue: 3
Pages: 218-26
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Publication
29531216 | J:259705
First Author: Rivat C
Year: 2018
Journal: Nat Commun
Title: Inhibition of neuronal FLT3 receptor tyrosine kinase alleviates peripheral neuropathic pain in mice.
Volume: 9
Issue: 1
Pages: 1042
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Publication
23772038 | J:204950
First Author: Gwin KA
Year: 2013
Journal: J Immunol
Title: Hoxa9 and Flt3 signaling synergistically regulate an early checkpoint in lymphopoiesis.
Volume: 191
Issue: 2
Pages: 745-54
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7630197 | J:27743
First Author: Brasel K
Year: 1995
Journal: Leukemia
Title: Expression of the flt3 receptor and its ligand on hematopoietic cells.
Volume: 9
Issue: 7
Pages: 1212-8
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Publication
24269847 | J:215723
First Author: Kamezaki K
Year: 2014
Journal: Exp Hematol
Title: Differential requirement for wild-type Flt3 in leukemia initiation among mouse models of human leukemia.
Volume: 42
Issue: 3
Pages: 192-203.e1
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Publication
23977266 | J:204431
First Author: Albouhair S
Year: 2013
Journal: PLoS One
Title: Flt3 does not play a critical role in murine myeloid leukemias induced by MLL fusion genes.
Volume: 8
Issue: 8
Pages: e72261
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Publication
16116483 | J:103427
First Author: Lee BH
Year: 2005
Journal: Oncogene
Title: FLT3 internal tandem duplication mutations induce myeloproliferative or lymphoid disease in a transgenic mouse model.
Volume: 24
Issue: 53
Pages: 7882-92
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Publication
21813452 | J:177063
First Author: Kharazi S
Year: 2011
Journal: Blood
Title: Impact of gene dosage, loss of wild-type allele, and FLT3 ligand on Flt3-ITD-induced myeloproliferation.
Volume: 118
Issue: 13
Pages: 3613-21
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7531700 | J:23709
First Author: Lavagna C
Year: 1995
Journal: J Biol Chem
Title: Identification and characterization of a functional murine FLT3 isoform produced by exon skipping.
Volume: 270
Issue: 7
Pages: 3165-71
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20951944 | J:165552
First Author: Rathinam C
Year: 2010
Journal: Cancer Cell
Title: Myeloid leukemia development in c-Cbl RING finger mutant mice is dependent on FLT3 signaling.
Volume: 18
Issue: 4
Pages: 341-52
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26382271 | J:243178
First Author: Volpe G
Year: 2015
Journal: PLoS One
Title: Regulation of the Flt3 Gene in Haematopoietic Stem and Early Progenitor Cells.
Volume: 10
Issue: 9
Pages: e0138257
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8896402 | J:36245
First Author: McClanahan T
Year: 1996
Journal: Blood
Title: Biochemical and genetic characterization of multiple splice variants of the Flt3 ligand.
Volume: 88
Issue: 9
Pages: 3371-82
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17936561 | J:126003
First Author: Lee BH
Year: 2007
Journal: Cancer Cell
Title: FLT3 mutations confer enhanced proliferation and survival properties to multipotent progenitors in a murine model of chronic myelomonocytic leukemia.
Volume: 12
Issue: 4
Pages: 367-80
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Publication
19830725 | J:155707
First Author: Kenins L
Year: 2010
Journal: Eur J Immunol
Title: Flt3 ligand-receptor interaction is important for maintenance of early thymic progenitor numbers in steady-state thymopoiesis.
Volume: 40
Issue: 1
Pages: 81-90
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19188666 | J:148292
First Author: Buza-Vidas N
Year: 2009
Journal: Blood
Title: FLT3 receptor and ligand are dispensable for maintenance and posttransplantation expansion of mouse hematopoietic stem cells.
Volume: 113
Issue: 15
Pages: 3453-60
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23741395 | J:200827
First Author: Wu X
Year: 2013
Journal: PLoS One
Title: Bcl11a controls Flt3 expression in early hematopoietic progenitors and is required for pDC development in vivo.
Volume: 8
Issue: 5
Pages: e64800
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8765501 | J:34954
First Author: Begley CG
Year: 1996
Journal: Exp Hematol
Title: Murine flt3 ligand protects M1 leukemic cells from LIF-induced differentiation and suppression of self-renewal.
Volume: 24
Issue: 10
Pages: 1247-57
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27617578 | J:236455
First Author: Staffas A
Year: 2017
Journal: Oncogene
Title: Upregulation of Flt3 is a passive event in Hoxa9/Meis1-induced acute myeloid leukemia in mice.
Volume: 36
Issue: 11
Pages: 1516-1524
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16418395 | J:118807
First Author: Onai N
Year: 2006
Journal: J Exp Med
Title: Activation of the Flt3 signal transduction cascade rescues and enhances type I interferon-producing and dendritic cell development.
Volume: 203
Issue: 1
Pages: 227-38
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20510871 | J:160816
First Author: Carotta S
Year: 2010
Journal: Immunity
Title: The transcription factor PU.1 controls dendritic cell development and Flt3 cytokine receptor expression in a dose-dependent manner.
Volume: 32
Issue: 5
Pages: 628-41
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24888589 | J:211638
First Author: Johnson RM
Year: 2014
Journal: Genes Dev
Title: MuLV-related endogenous retroviral elements and Flt3 participate in aberrant end-joining events that promote B-cell leukemogenesis.
Volume: 28
Issue: 11
Pages: 1179-90
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26903243 | J:232928
First Author: Lau CM
Year: 2016
Journal: J Exp Med
Title: Leukemia-associated activating mutation of Flt3 expands dendritic cells and alters T cell responses.
Volume: 213
Issue: 3
Pages: 415-31
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17540845 | J:148909
First Author: Sitnicka E
Year: 2007
Journal: Blood
Title: Critical role of FLT3 ligand in IL-7 receptor independent T lymphopoiesis and regulation of lymphoid-primed multipotent progenitors.
Volume: 110
Issue: 8
Pages: 2955-64
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36739348 | J:335077
First Author: Straube J
Year: 2023
Journal: Leukemia
Title: Cre recombinase expression cooperates with homozygous FLT3 internal tandem duplication knockin mouse model to induce acute myeloid leukemia.
Volume: 37
Issue: 4
Pages: 741-750
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36073548 | J:329450
 
First Author: Ramdas B
Year: 2022
Journal: JCI Insight
Title: Combined heterozygosity of FLT3 ITD, TET2, and DNMT3A results in aggressive leukemia.
Volume: 7
Issue: 17
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27099147 | J:234793
First Author: Uras IZ
Year: 2016
Journal: Blood
Title: Palbociclib treatment of FLT3-ITD+ AML cells uncovers a kinase-dependent transcriptional regulation of FLT3 and PIM1 by CDK6.
Volume: 127
Issue: 23
Pages: 2890-902
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24444745 | J:215709
First Author: Dolence JJ
Year: 2014
Journal: Exp Hematol
Title: Flt3 signaling regulates the proliferation, survival, and maintenance of multipotent hematopoietic progenitors that generate B cell precursors.
Volume: 42
Issue: 5
Pages: 380-393.e3
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36206490 | J:333323
First Author: Chen H
Year: 2023
Journal: Blood
Title: PRL2 phosphatase enhances oncogenic FLT3 signaling via dephosphorylation of the E3 ubiquitin ligase CBL at tyrosine 371.
Volume: 141
Issue: 3
Pages: 244-259
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7824267 | J:22411
First Author: Lyman SD
Year: 1995
Journal: Oncogene
Title: Identification of soluble and membrane-bound isoforms of the murine flt3 ligand generated by alternative splicing of mRNAs.
Volume: 10
Issue: 1
Pages: 149-57
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21967974 | J:179097
First Author: Avagyan S
Year: 2011
Journal: Blood
Title: Quantitative trait mapping reveals a regulatory axis involving peroxisome proliferator-activated receptors, PRDM16, transforming growth factor-β2 and FLT3 in hematopoiesis.
Volume: 118
Issue: 23
Pages: 6078-86
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18245664 | J:133528
First Author: Li L
Year: 2008
Journal: Blood
Title: Knock-in of an internal tandem duplication mutation into murine FLT3 confers myeloproliferative disease in a mouse model.
Volume: 111
Issue: 7
Pages: 3849-58
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8183574 | J:18780
First Author: Rottapel R
Year: 1994
Journal: Oncogene
Title: Substrate specificities and identification of a putative binding site for PI3K in the carboxy tail of the murine Flt3 receptor tyrosine kinase.
Volume: 9
Issue: 6
Pages: 1755-65
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12387740 | J:79569
First Author: Sitnicka E
Year: 2002
Journal: Immunity
Title: Key role of flt3 ligand in regulation of the common lymphoid progenitor but not in maintenance of the hematopoietic stem cell pool.
Volume: 17
Issue: 4
Pages: 463-72
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16863910 | J:111904
First Author: Fukuda S
Year: 2006
Journal: Exp Hematol
Title: Internal tandem duplication of Flt3 modulates chemotaxis and survival of hematopoietic cells by SDF1alpha but negatively regulates marrow homing in vivo.
Volume: 34
Issue: 8
Pages: 1041-51
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27387666 | J:248809
First Author: Abe M
Year: 2016
Journal: PLoS One
Title: Internal Tandem Duplication in FLT3 Attenuates Proliferation and Regulates Resistance to the FLT3 Inhibitor AC220 by Modulating p21Cdkn1a and Pbx1 in Hematopoietic Cells.
Volume: 11
Issue: 7
Pages: e0158290
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8380915 | J:3709
First Author: Rosnet O
Year: 1993
Journal: Oncogene
Title: Close physical linkage of the FLT1 and FLT3 genes on chromosome 13 in man and chromosome 5 in mouse.
Volume: 8
Issue: 1
Pages: 173-9
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9345066 | J:43756
First Author: Brasel K
Year: 1997
Journal: Blood
Title: Flt3 ligand synergizes with granulocyte-macrophage colony-stimulating factor or granulocyte colony-stimulating factor to mobilize hematopoietic progenitor cells into the peripheral blood of mice.
Volume: 90
Issue: 9
Pages: 3781-8
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19830741 | J:155704
First Author: Bozzacco L
Year: 2010
Journal: Eur J Immunol
Title: HIV gag protein is efficiently cross-presented when targeted with an antibody towards the DEC-205 receptor in Flt3 ligand-mobilized murine DC.
Volume: 40
Issue: 1
Pages: 36-46
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22674806 | J:189096
First Author: Zorko NA
Year: 2012
Journal: Blood
Title: Mll partial tandem duplication and Flt3 internal tandem duplication in a double knock-in mouse recapitulates features of counterpart human acute myeloid leukemias.
Volume: 120
Issue: 5
Pages: 1130-6
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23418353 | J:213100
First Author: Smith CJ
Year: 2013
Journal: J Cell Sci
Title: The E3 ubiquitin ligases RNF126 and Rabring7 regulate endosomal sorting of the epidermal growth factor receptor.
Volume: 126
Issue: Pt 6
Pages: 1366-80
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20360400 | J:162445
First Author: Tsuruyama T
Year: 2010
Journal: J Leukoc Biol
Title: Dual retrovirus integration tagging: identification of new signaling molecules Fiz1 and Hipk2 that are involved in the IL-7 signaling pathway in B lymphoblastic lymphomas.
Volume: 88
Issue: 1
Pages: 107-16
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2004790 | J:11061
First Author: Rosnet O
Year: 1991
Journal: Genomics
Title: Isolation and chromosomal localization of a novel FMS-like tyrosine kinase gene.
Volume: 9
Issue: 2
Pages: 380-5
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22958930 | J:193429
First Author: Chu SH
Year: 2012
Journal: Cell Stem Cell
Title: FLT3-ITD knockin impairs hematopoietic stem cell quiescence/homeostasis, leading to myeloproliferative neoplasm.
Volume: 11
Issue: 3
Pages: 346-58
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21726834 | J:174372
First Author: Boyer SW
Year: 2011
Journal: Cell Stem Cell
Title: All hematopoietic cells develop from hematopoietic stem cells through Flk2/Flt3-positive progenitor cells.
Volume: 9
Issue: 1
Pages: 64-73
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24333663 | J:215713
First Author: Beaudin AE
Year: 2014
Journal: Exp Hematol
Title: Flk2/Flt3 promotes both myeloid and lymphoid development by expanding non-self-renewing multipotent hematopoietic progenitor cells.
Volume: 42
Issue: 3
Pages: 218-229.e4
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1319394 | J:919
First Author: Galland F
Year: 1992
Journal: Genomics
Title: Chromosomal localization of FLT4, a novel receptor-type tyrosine kinase gene.
Volume: 13
Issue: 2
Pages: 475-8
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21908433 | J:178792
First Author: Li L
Year: 2011
Journal: Blood
Title: Loss of the wild-type allele contributes to myeloid expansion and disease aggressiveness in FLT3/ITD knockin mice.
Volume: 118
Issue: 18
Pages: 4935-45
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24255108 | J:205200
First Author: Bailey E
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: FLT3/D835Y mutation knock-in mice display less aggressive disease compared with FLT3/internal tandem duplication (ITD) mice.
Volume: 110
Issue: 52
Pages: 21113-8
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23691170 | J:202169
First Author: Khandelwal P
Year: 2013
Journal: PLoS One
Title: Ocular mucosal CD11b+ and CD103+ mouse dendritic cells under normal conditions and in allergic immune responses.
Volume: 8
Issue: 5
Pages: e64193
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21228325 | J:170520
First Author: Li L
Year: 2011
Journal: Blood
Title: Defective nonhomologous end joining blocks B-cell development in FLT3/ITD mice.
Volume: 117
Issue: 11
Pages: 3131-9
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28432220 | J:243341
First Author: Wallace JA
Year: 2017
Journal: Blood
Title: miR-155 promotes FLT3-ITD-induced myeloproliferative disease through inhibition of the interferon response.
Volume: 129
Issue: 23
Pages: 3074-3086
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30674471 | J:276215
First Author: Esnault C
Year: 2019
Journal: Blood
Title: FLT3-ITD impedes retinoic acid, but not arsenic, responses in murine acute promyelocytic leukemias.
Volume: 133
Issue: 13
Pages: 1495-1506
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20807885 | J:167425
First Author: Fan J
Year: 2010
Journal: Blood
Title: Cells expressing FLT3/ITD mutations exhibit elevated repair errors generated through alternative NHEJ pathways: implications for genomic instability and therapy.
Volume: 116
Issue: 24
Pages: 5298-305
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15951813 | J:99149
First Author: Sambandam A
Year: 2005
Journal: Nat Immunol
Title: Notch signaling controls the generation and differentiation of early T lineage progenitors.
Volume: 6
Issue: 7
Pages: 663-70
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20065110 | J:159490
First Author: Li LX
Year: 2010
Journal: J Immunol
Title: A Flt3- and Ras-dependent pathway primes B cell development by inducing a state of IL-7 responsiveness.
Volume: 184
Issue: 4
Pages: 1728-36
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27300438 | J:232326
First Author: Yang L
Year: 2016
Journal: Cancer Cell
Title: DNMT3A Loss Drives Enhancer Hypomethylation in FLT3-ITD-Associated Leukemias.
Volume: 29
Issue: 6
Pages: 922-934
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25873173 | J:220302
First Author: Shih AH
Year: 2015
Journal: Cancer Cell
Title: Mutational cooperativity linked to combinatorial epigenetic gain of function in acute myeloid leukemia.
Volume: 27
Issue: 4
Pages: 502-15
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30651561 | J:270609
First Author: Zhang H
Year: 2019
Journal: Nat Commun
Title: Clinical resistance to crenolanib in acute myeloid leukemia due to diverse molecular mechanisms.
Volume: 10
Issue: 1
Pages: 244
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25336251 | J:225705
 
First Author: Scheffler JM
Year: 2014
Journal: Nat Commun
Title: LAMTOR2 regulates dendritic cell homeostasis through FLT3-dependent mTOR signalling.
Volume: 5
Pages: 5138
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Publication
23727242 | J:199313
First Author: Mead AJ
Year: 2013
Journal: Cell Rep
Title: FLT3-ITDs instruct a myeloid differentiation and transformation bias in lymphomyeloid multipotent progenitors.
Volume: 3
Issue: 6
Pages: 1766-76
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Publication
23685841 | J:198677
First Author: Guermonprez P
Year: 2013
Journal: Nat Med
Title: Inflammatory Flt3l is essential to mobilize dendritic cells and for T cell responses during Plasmodium infection.
Volume: 19
Issue: 6
Pages: 730-8
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Publication
20096329 | J:158349
First Author: Heuser M
Year: 2010
Journal: Exp Hematol
Title: Extrinsic signals determine myeloid-erythroid lineage switch in MN1 leukemia.
Volume: 38
Issue: 3
Pages: 174-9
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Publication
38433905 | J:347776
First Author: Yu CI
Year: 2024
Journal: iScience
Title: Engraftment of adult hematopoietic stem and progenitor cells in a novel model of humanized mice.
Volume: 27
Issue: 3
Pages: 109238
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Publication
29572360 | J:261590
First Author: Durai V
Year: 2018
Journal: J Exp Med
Title: Altered compensatory cytokine signaling underlies the discrepancy between Flt3-/- and Flt3l-/- mice.
Volume: 215
Issue: 5
Pages: 1417-1435
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Publication
27879203 | J:239173
   
First Author: Porter SN
Year: 2016
Journal: Elife
Title: Fetal and neonatal hematopoietic progenitors are functionally and transcriptionally resistant to Flt3-ITD mutations.
Volume: 5
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Publication
34903561 | J:319540
 
First Author: Della Verde G
Year: 2022
Journal: Life Sci Alliance
Title: Fms-like tyrosine kinase 3 is a regulator of the cardiac side population in mice.
Volume: 5
Issue: 3
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Publication
24085765 | J:204600
First Author: Bernot KM
Year: 2013
Journal: Blood
Title: Eradicating acute myeloid leukemia in a Mll(PTD/wt):Flt3(ITD/wt) murine model: a path to novel therapeutic approaches for human disease.
Volume: 122
Issue: 23
Pages: 3778-83
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Publication
33519816 | J:312590
 
First Author: Bosteels C
Year: 2020
Journal: Front Immunol
Title: CCR2- and Flt3-Dependent Inflammatory Conventional Type 2 Dendritic Cells Are Necessary for the Induction of Adaptive Immunity by the Human Vaccine Adjuvant System AS01.
Volume: 11
Pages: 606805
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Publication
27636998 | J:309648
First Author: Poitras JL
Year: 2016
Journal: Oncotarget
Title: Dnmt3a deletion cooperates with the Flt3/ITD mutation to drive leukemogenesis in a murine model.
Volume: 7
Issue: 43
Pages: 69124-69135
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Publication
24855208 | J:214302
First Author: Sasca D
Year: 2014
Journal: Blood
Title: SIRT1 prevents genotoxic stress-induced p53 activation in acute myeloid leukemia.
Volume: 124
Issue: 1
Pages: 121-33
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Publication
30450160 | J:279400
First Author: Annesley CE
Year: 2018
Journal: Oncotarget
Title: Knock-in of the Wt1 R394W mutation causes MDS and cooperates with Flt3/ITD to drive aggressive myeloid neoplasms in mice.
Volume: 9
Issue: 82
Pages: 35313-35326
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Publication
24184354 | J:215728
First Author: Rau R
Year: 2014
Journal: Exp Hematol
Title: NPMc+ cooperates with Flt3/ITD mutations to cause acute leukemia recapitulating human disease.
Volume: 42
Issue: 2
Pages: 101-13.e5
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Publication
22318449 | J:190781
First Author: Reckzeh K
Year: 2012
Journal: Leukemia
Title: Molecular and cellular effects of oncogene cooperation in a genetically accurate AML mouse model.
Volume: 26
Issue: 7
Pages: 1527-36
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Publication
30820040 | J:295283
First Author: Kresinsky A
Year: 2019
Journal: Oncogene
Title: Lack of CD45 in FLT3-ITD mice results in a myeloproliferative phenotype, cortical porosity, and ectopic bone formation.
Volume: 38
Issue: 24
Pages: 4773-4787
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Publication
24954893 | J:220050
First Author: Guerrero AD
Year: 2014
Journal: Immunology
Title: Interleukin-2-mediated inhibition of dendritic cell development correlates with decreased CD135 expression and increased monocyte/macrophage precursors.
Volume: 143
Issue: 4
Pages: 640-50
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Publication
9620281 | J:47896
First Author: Ogawa M
Year: 1998
Journal: Exp Hematol
Title: Flt3/Flk-2 and c-Kit are not essential for the proliferation of B lymphoid progenitor cells in the bone marrow of the adult mouse.
Volume: 26
Issue: 6
Pages: 478-88
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