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Search results 1 to 100 out of 246 for Gusb

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Category: Publication
Type Details Score
Publication
First Author: Ray J
Year: 1998
Journal: Genomics
Title: Cloning of the canine beta-glucuronidase cDNA, mutation identification in canine MPS VII, and retroviral vector-mediated correction of MPS VII cells.
Volume: 48
Issue: 2
Pages: 248-53
Publication
First Author: Bramwell KK
Year: 2014
Journal: J Clin Invest
Title: Lysosomal β-glucuronidase regulates Lyme and rheumatoid arthritis severity.
Volume: 124
Issue: 1
Pages: 311-20
Publication
First Author: Kyle JW
Year: 1990
Journal: Proc Natl Acad Sci U S A
Title: Correction of murine mucopolysaccharidosis VII by a human beta-glucuronidase transgene.
Volume: 87
Issue: 10
Pages: 3914-8
Publication
First Author: Daly TM
Year: 1999
Journal: Proc Natl Acad Sci U S A
Title: Neonatal gene transfer leads to widespread correction of pathology in a murine model of lysosomal storage disease.
Volume: 96
Issue: 5
Pages: 2296-300
Publication
First Author: Donsante A
Year: 2001
Journal: Gene Ther
Title: Observed incidence of tumorigenesis in long-term rodent studies of rAAV vectors.
Volume: 8
Issue: 17
Pages: 1343-6
Publication
First Author: Frisella WA
Year: 2001
Journal: Mol Ther
Title: Intracranial injection of recombinant adeno-associated virus improves cognitive function in a murine model of mucopolysaccharidosis type VII.
Volume: 3
Issue: 3
Pages: 351-8
Publication
First Author: Hofling AA
Year: 2003
Journal: Blood
Title: Engraftment of human CD34+ cells leads to widespread distribution of donor-derived cells and correction of tissue pathology in a novel murine xenotransplantation model of lysosomal storage disease.
Volume: 101
Issue: 5
Pages: 2054-63
Publication
First Author: Yasue M
Year: 1991
Journal: Cytogenet Cell Genet
Title: Chromosomal assignments of 23 biochemical loci of the rat by using rat x mouse somatic cell hybrids.
Volume: 57
Issue: 2-3
Pages: 142-8
Publication
First Author: Gallagher PM
Year: 1987
Journal: Genomics
Title: DNA sequence variation within the beta-glucuronidase gene complex among inbred strains of mice.
Volume: 1
Issue: 2
Pages: 145-52
Publication
First Author: Gallagher PM
Year: 1988
Journal: Genomics
Title: The complete nucleotide sequence of murine beta-glucuronidase mRNA and its deduced polypeptide.
Volume: 2
Issue: 3
Pages: 215-9
Publication
First Author: D'Amore MA
Year: 1988
Journal: Biochemistry
Title: Complete sequence and organization of the murine beta-glucuronidase gene.
Volume: 27
Issue: 18
Pages: 7131-40
Publication
First Author: Wawrzyniak CJ
Year: 1989
Journal: Mol Cell Biol
Title: DNA determinants of structural and regulatory variation within the murine beta-glucuronidase gene complex.
Volume: 9
Issue: 9
Pages: 4074-8
Publication
First Author: Funkenstein B
Year: 1988
Journal: Mol Cell Biol
Title: Genomic organization and sequence of the Gus-s alpha allele of the murine beta-glucuronidase gene.
Volume: 8
Issue: 3
Pages: 1160-8
Publication
First Author: Ohlemiller KK
Year: 2002
Journal: Hear Res
Title: Inner ear pathology in the mucopolysaccharidosis VII mouse.
Volume: 169
Issue: 1-2
Pages: 69-84
Publication
First Author: Tomatsu S
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: Missense models [Gustm(E536A)Sly, Gustm(E536Q)Sly, and Gustm(L175F)Sly] of murine mucopolysaccharidosis type VII produced by targeted mutagenesis.
Volume: 99
Issue: 23
Pages: 14982-7
Publication
First Author: Tomatsu S
Year: 2003
Journal: Hum Mol Genet
Title: Production of MPS VII mouse (Gus(tm(hE540A x mE536A)Sly)) doubly tolerant to human and mouse beta-glucuronidase.
Volume: 12
Issue: 9
Pages: 961-73
Publication  
First Author: Yamashita T
Year: 2020
Journal: Endocrinology
Title: C-Type Natriuretic Peptide Restores Growth Impairment Under Enzyme Replacement in Mice With Mucopolysaccharidosis VII.
Volume: 161
Issue: 2
Publication
First Author: Vogler C
Year: 2001
Journal: Pediatr Res
Title: A novel model of murine mucopolysaccharidosis type VII due to an intracisternal a particle element transposition into the beta-glucuronidase gene: clinical and pathologic findings.
Volume: 49
Issue: 3
Pages: 342-8
Publication
First Author: Kashiwagi M
Year: 2022
Journal: PLoS One
Title: Circulatory C-type natriuretic peptide reduces mucopolysaccharidosis-associated craniofacial hypoplasia in vivo.
Volume: 17
Issue: 11
Pages: e0277140
Publication
First Author: Ohashi T
Year: 1997
Journal: Proc Natl Acad Sci U S A
Title: Adenovirus-mediated gene transfer and expression of human beta-glucuronidase gene in the liver, spleen, and central nervous system in mucopolysaccharidosis type VII mice.
Volume: 94
Issue: 4
Pages: 1287-92
Publication
First Author: Woloszynek JC
Year: 2004
Journal: Biochem J
Title: Numerous transcriptional alterations in liver persist after short-term enzyme-replacement therapy in a murine model of mucopolysaccharidosis type VII.
Volume: 379
Issue: Pt 2
Pages: 461-9
Publication
First Author: Snyder EY
Year: 1995
Journal: Nature
Title: Neural progenitor cell engraftment corrects lysosomal storage throughout the MPS VII mouse brain.
Volume: 374
Issue: 6520
Pages: 367-70
Publication
First Author: Sly WS
Year: 2001
Journal: Proc Natl Acad Sci U S A
Title: Active site mutant transgene confers tolerance to human beta-glucuronidase without affecting the phenotype of MPS VII mice.
Volume: 98
Issue: 5
Pages: 2205-10
Publication
First Author: Casal ML
Year: 2000
Journal: Pediatr Res
Title: Mucopolysaccharidosis type VII in the developing mouse fetus.
Volume: 47
Issue: 6
Pages: 750-6
Publication
First Author: Chang PL
Year: 1993
Journal: Neuroreport
Title: Behavioural abnormalities in a murine model of a human lysosomal storage disease.
Volume: 4
Issue: 5
Pages: 507-10
Publication
First Author: Monroy MA
Year: 2002
Journal: Bone
Title: Abnormal osteoclast morphology and bone remodeling in a murine model of a lysosomal storage disease.
Volume: 30
Issue: 2
Pages: 352-9
Publication
First Author: Sferra TJ
Year: 2000
Journal: Hum Gene Ther
Title: Recombinant adeno-associated virus-mediated correction of lysosomal storage within the central nervous system of the adult mucopolysaccharidosis type VII mouse.
Volume: 11
Issue: 4
Pages: 507-19
Publication
First Author: Berry CL
Year: 1994
Journal: Lab Invest
Title: Pathology of the ear in murine mucopolysaccharidosis type VII. Morphologic correlates of hearing loss.
Volume: 71
Issue: 3
Pages: 438-45
Publication
First Author: Skorupa AF
Year: 1999
Journal: Exp Neurol
Title: Sustained production of beta-glucuronidase from localized sites after AAV vector gene transfer results in widespread distribution of enzyme and reversal of lysosomal storage lesions in a large volume of brain in mucopolysaccharidosis VII mice.
Volume: 160
Issue: 1
Pages: 17-27
Publication
First Author: Ghodsi A
Year: 1999
Journal: Exp Neurol
Title: Systemic hyperosmolality improves beta-glucuronidase distribution and pathology in murine MPS VII brain following intraventricular gene transfer.
Volume: 160
Issue: 1
Pages: 109-16
Publication
First Author: Barker JE
Year: 2001
Journal: Blood Cells Mol Dis
Title: In utero fetal liver cell transplantation without toxic irradiation alleviates lysosomal storage in mice with mucopolysaccharidosis type VII.
Volume: 27
Issue: 5
Pages: 861-73
Publication
First Author: Stein CS
Year: 1999
Journal: J Virol
Title: Systemic and central nervous system correction of lysosomal storage in mucopolysaccharidosis type VII mice.
Volume: 73
Issue: 4
Pages: 3424-9
Publication
First Author: Sands MS
Year: 1994
Journal: J Clin Invest
Title: Enzyme replacement therapy for murine mucopolysaccharidosis type VII.
Volume: 93
Issue: 6
Pages: 2324-31
Publication
First Author: Freeman BJ
Year: 1999
Journal: Blood
Title: Behavior and therapeutic efficacy of beta-glucuronidase-positive mononuclear phagocytes in a murine model of mucopolysaccharidosis type VII.
Volume: 94
Issue: 6
Pages: 2142-50
Publication
First Author: Birkenmeier EH
Year: 1991
Journal: Blood
Title: Increased life span and correction of metabolic defects in murine mucopolysaccharidosis type VII after syngeneic bone marrow transplantation.
Volume: 78
Issue: 11
Pages: 3081-92
Publication
First Author: Casal ML
Year: 1998
Journal: Lab Invest
Title: Variant clinical course of mucopolysaccharidosis type VII in two groups of mice carrying the same mutation.
Volume: 78
Issue: 12
Pages: 1575-81
Publication
First Author: Sands MS
Year: 1993
Journal: Proc Natl Acad Sci U S A
Title: A single-base-pair deletion in the beta-glucuronidase gene accounts for the phenotype of murine mucopolysaccharidosis type VII.
Volume: 90
Issue: 14
Pages: 6567-71
Publication
First Author: Vogler C
Year: 1993
Journal: Pediatr Res
Title: Enzyme replacement with recombinant beta-glucuronidase in the newborn mucopolysaccharidosis type VII mouse.
Volume: 34
Issue: 6
Pages: 837-40
Publication
First Author: Poorthuis BJ
Year: 1994
Journal: Pediatr Res
Title: Bone marrow transplantation has a significant effect on enzyme levels and storage of glycosaminoglycans in tissues and in isolated hepatocytes of mucopolysaccharidosis type VII mice.
Volume: 36
Issue: 2
Pages: 187-93
Publication
First Author: Coulson-Thomas VJ
Year: 2013
Journal: Stem Cells
Title: Transplantation of human umbilical mesenchymal stem cells cures the corneal defects of mucopolysaccharidosis VII mice.
Volume: 31
Issue: 10
Pages: 2116-26
Publication
First Author: Ohlemiller KK
Year: 2000
Journal: Exp Eye Res
Title: Retinal function is improved in a murine model of a lysosomal storage disease following bone marrow transplantation.
Volume: 71
Issue: 5
Pages: 469-81
Publication
First Author: Parente MK
Year: 2012
Journal: PLoS One
Title: Dysregulation of gene expression in a lysosomal storage disease varies between brain regions implicating unexpected mechanisms of neuropathology.
Volume: 7
Issue: 3
Pages: e32419
Publication
First Author: O'Connor LH
Year: 1998
Journal: J Clin Invest
Title: Enzyme replacement therapy for murine mucopolysaccharidosis type VII leads to improvements in behavior and auditory function.
Volume: 101
Issue: 7
Pages: 1394-400
Publication
First Author: Parente MK
Year: 2016
Journal: Mol Genet Metab
Title: Integrated analysis of proteome and transcriptome changes in the mucopolysaccharidosis type VII mouse hippocampus.
Volume: 118
Issue: 1
Pages: 41-54
Publication
First Author: Moullier P
Year: 1993
Journal: Nat Genet
Title: Correction of lysosomal storage in the liver and spleen of MPS VII mice by implantation of genetically modified skin fibroblasts.
Volume: 4
Issue: 2
Pages: 154-9
Publication
First Author: Bastedo L
Year: 1994
Journal: J Clin Invest
Title: Behavioral consequences of bone marrow transplantation in the treatment of murine mucopolysaccharidosis type VII.
Volume: 94
Issue: 3
Pages: 1180-6
Publication
First Author: Derrick-Roberts AL
Year: 2016
Journal: Mol Genet Metab
Title: Reversal of established bone pathology in MPS VII mice following lentiviral-mediated gene therapy.
Volume: 119
Issue: 3
Pages: 249-257
Publication
First Author: Wolfe JH
Year: 1992
Journal: Nat Genet
Title: Herpesvirus vector gene transfer and expression of beta-glucuronidase in the central nervous system of MPS VII mice.
Volume: 1
Issue: 5
Pages: 379-84
Publication      
First Author: Kane CC
Year: 2008
Journal: MGI Direct Data Submission
Title: Mucopolysaccharidosis VII 3 Jackson, a new remutation of beta glucuronidase
Publication  
First Author: Urosevic N
Year: 1999
Journal: J Gen Virol
Title: Development and characterization of new flavivirus-resistant mouse strains bearing Flv(r)-like and Flv(mr) alleles from wild or wild-derived mice.
Volume: 80 ( Pt 4)
Pages: 897-906
Publication
First Author: Glaser JH
Year: 1980
Journal: J Biol Chem
Title: Multiple kinetic forms of beta-glucuronidase.
Volume: 255
Issue: 5
Pages: 1879-94
Publication
First Author: Longas MO
Year: 1981
Journal: Biochem J
Title: Sequential hydrolysis of hyaluronate by beta-glucuronidase and beta-N-acetylhexosaminidase.
Volume: 197
Issue: 2
Pages: 275-82
Publication
First Author: Ganschow R
Year: 1968
Journal: Genetics
Title: Glucuronidase phenotypes of inbred mouse strains.
Volume: 59
Issue: 3
Pages: 335-49
Publication
First Author: Swank RT
Year: 1973
Journal: Science
Title: Recombinant inbred lines: value in the genetic analysis of biochemical variants.
Volume: 181
Issue: 4106
Pages: 1249-52
Publication
First Author: Lundin LG
Year: 1973
Journal: Biochem Genet
Title: Simple inheritance of variations in male mouse kidney beta-glucuronidase activity.
Volume: 10
Issue: 4
Pages: 333-40
Publication
First Author: Paigen K
Year: 1975
Journal: J Cell Physiol
Title: The molecular genetics of mammalian glucuronidase.
Volume: 85
Issue: 2 Pt 2 Suppl 1
Pages: 379-92
Publication
First Author: Wudl L
Year: 1976
Journal: Dev Biol
Title: The expression of beta-glucuronidase during preimplantation development of mouse embryos.
Volume: 48
Issue: 1
Pages: 104-9
Publication
First Author: Lusis AJ
Year: 1978
Journal: J Biol Chem
Title: The large scale isolation of mouse beta-glucuronidase and comparison of allozymes.
Volume: 253
Issue: 20
Pages: 7336-45
Publication
First Author: Paigen K
Year: 1979
Journal: Science
Title: A regulatory locus for mouse beta-glucuronidase induction, Gur, controls messenger RNA activity.
Volume: 203
Issue: 4380
Pages: 554-6
Publication
First Author: Watson G
Year: 1978
Journal: Biochem Genet
Title: Segregation of genetic determinants for murine glucuronidase synthesis and loss in CXB recombinant-inbred strains.
Volume: 16
Issue: 9-10
Pages: 897-903
Publication
First Author: Meredith SA
Year: 1978
Journal: Genetics
Title: Apparent trans control of murine beta-glucuronidase synthesis by a temporal genetic element.
Volume: 90
Issue: 4
Pages: 725-34
Publication
First Author: Watson G
Year: 1981
Journal: J Biol Chem
Title: Genetic determination of kinetic parameters in beta-glucuronidase induction by androgen.
Volume: 256
Issue: 6
Pages: 3005-11
Publication  
Year: 1981
Journal: Hereditas
Title: Abstracts of papers presented at the Workshop on Molecular Genetics of the Mouse II. August 11-16, 1980, Sandbjerg Slot, Sønderborg, Denmark.
Volume: 94
Issue: 1
Pages: 1-20
Publication
First Author: Pfister K
Year: 1982
Journal: Biochem Genet
Title: Expression of beta-glucuronidase haplotypes in prototype and congenic mouse strains.
Volume: 20
Issue: 5-6
Pages: 519-36
Publication
First Author: Lusis AJ
Year: 1983
Journal: Proc Natl Acad Sci U S A
Title: Trans-acting temporal locus within the beta-glucuronidase gene complex.
Volume: 80
Issue: 14
Pages: 4398-402
Publication
First Author: Catterall JF
Year: 1983
Journal: Biochemistry
Title: Detection of early changes in androgen-induced mouse renal beta-glucuronidase messenger ribonucleic acid using cloned complementary deoxyribonucleic acid.
Volume: 22
Issue: 26
Pages: 6049-53
Publication
First Author: Watson G
Year: 1985
Journal: Gene
Title: Properties of rat and mouse beta-glucuronidase mRNA and cDNA, including evidence for sequence polymorphism and genetic regulation of mRNA levels.
Volume: 36
Issue: 1-2
Pages: 15-25
Publication
First Author: Bevilacqua A
Year: 1988
Journal: Proc Natl Acad Sci U S A
Title: Antisense RNA inhibits endogenous gene expression in mouse preimplantation embryos: lack of double-stranded RNA "melting" activity.
Volume: 85
Issue: 3
Pages: 831-5
Publication
First Author: Moore KJ
Year: 1988
Journal: Genomics
Title: Genome organization and polymorphism of the murine beta-glucuronidase region.
Volume: 2
Issue: 1
Pages: 25-31
Publication
First Author: Wang B
Year: 1988
Journal: J Biol Chem
Title: Overlapping transcriptional units on the same strand within the murine beta-glucuronidase gene complex.
Volume: 263
Issue: 31
Pages: 15841-4
Publication
First Author: Zhen L
Year: 1995
Journal: J Biol Chem
Title: The beta-glucuronidase propeptide contains a serpin-related octamer necessary for complex formation with egasyn esterase and for retention within the endoplasmic reticulum.
Volume: 270
Issue: 20
Pages: 11912-20
Publication  
First Author: PAIGEN K
Year: 1961
Journal: Nature
Title: Two linked genes showing a similar timing of expression in mice.
Volume: 190
Pages: 148-50
Publication  
First Author: PAIGEN K
Year: 1961
Journal: Proc Natl Acad Sci U S A
Title: The genetic control of enzyme activity during differentiation.
Volume: 47
Pages: 1641-9
Publication
First Author: Bush RM
Year: 1992
Journal: Evolution
Title: EVOLUTION OF β-GLUCURONIDASE REGULATION IN THE GENUS MUS.
Volume: 46
Issue: 1
Pages: 1-15
Publication
First Author: Paigen K
Year: 1984
Journal: Dev Genet
Title: Cell specificity in the developmental regulation of acid hydrolases by temporal genes.
Volume: 5
Issue: 2
Pages: 83-91
Publication      
First Author: Paigen K
Year: 1971
Title: The genetics of enzyme realization
Pages: 1-46
Publication    
First Author: Strausberg R
Year: 2001
Journal: GenBank Submission
Title: Mus musculus, similar to beta-glucuronidase structural, clone MGC: 6199 IMAGE: 3585664, mRNA, complete cds
Pages: BC004616
Publication  
First Author: Ganschow R
Year: 1986
Journal: Mouse News Lett
Title: The molecular genetics of murine beta-glucuronidase
Volume: 76
Pages: 53
Publication
First Author: Swank RT
Year: 1973
Journal: J Mol Biol
Title: Genetic control of glucuronidase induction in mice.
Volume: 81
Issue: 2
Pages: 225-43
Publication  
First Author: Beamer WG
Year: 1982
Journal: Mouse News Lett
Title: [Adipose storage deficiency (asd)].
Volume: 67
Pages: 21
Publication
First Author: Faust JR
Year: 1994
Journal: J Biol Chem
Title: Two related proteolipids and dolichol-linked oligosaccharides accumulate in motor neuron degeneration mice (mnd/mnd), a model for neuronal ceroid lipofuscinosis.
Volume: 269
Issue: 13
Pages: 10150-5
Publication
First Author: Wang D
Year: 2010
Journal: Mol Genet Metab
Title: Characterization of an MPS I-H knock-in mouse that carries a nonsense mutation analogous to the human IDUA-W402X mutation.
Volume: 99
Issue: 1
Pages: 62-71
Publication
First Author: Chen YH
Year: 2009
Journal: Nat Med
Title: Molecular signatures of disease brain endothelia provide new sites for CNS-directed enzyme therapy.
Volume: 15
Issue: 10
Pages: 1215-8
Publication
First Author: Tomatsu S
Year: 2003
Journal: Hum Mol Genet
Title: Mouse model of N-acetylgalactosamine-6-sulfate sulfatase deficiency (Galns-/-) produced by targeted disruption of the gene defective in Morquio A disease.
Volume: 12
Issue: 24
Pages: 3349-58
Publication
First Author: Sly WS
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Enzyme therapy in mannose receptor-null mucopolysaccharidosis VII mice defines roles for the mannose 6-phosphate and mannose receptors.
Volume: 103
Issue: 41
Pages: 15172-7
Publication
First Author: Birkenmeier EH
Year: 1989
Journal: J Clin Invest
Title: Murine mucopolysaccharidosis type VII. Characterization of a mouse with beta-glucuronidase deficiency.
Volume: 83
Issue: 4
Pages: 1258-66
Publication
First Author: Hudec PP
Year: 1974
Journal: Science
Title: Lysosomal and microsomal glucuronidase: genetic variant alters electrophoretic mobility of both hydrolases.
Volume: 185
Issue: 4149
Pages: 442-4
Publication
First Author: Dizik M
Year: 1977
Journal: Biochem Genet
Title: A gene apparently determining the extent of sialylation of lysosomal alpha-mannosidase in mouse liver.
Volume: 15
Issue: 1-2
Pages: 31-46
Publication
First Author: Kozak CA
Year: 1979
Journal: Science
Title: Genetic mapping of the ecotropic murine leukemia virus-inducing locus of BALB/c mouse to chromosome 5.
Volume: 204
Issue: 4388
Pages: 69-71
Publication  
First Author: Paigen K
Year: 1979
Journal: Annu Rev Genet
Title: Acid hydrolases as models of genetic control.
Volume: 13
Pages: 417-66
Publication
First Author: Schreiber R
Year: 2009
Journal: J Lipid Res
Title: Esterase 22 and beta-glucuronidase hydrolyze retinoids in mouse liver.
Volume: 50
Issue: 12
Pages: 2514-23
Publication  
First Author: Dizik M
Year: 1977
Journal: Mouse News Lett
Title: Genes controlling the processing of alpha-mannosidase.
Volume: 56
Pages: 58
Publication
First Author: Bertuzzi S
Year: 1996
Journal: Genomics
Title: Molecular cloning, structure, and chromosomal localization of the mouse LIM/homeobox gene Lhx5.
Volume: 36
Issue: 2
Pages: 234-9
Publication
First Author: Soper BW
Year: 1999
Journal: Exp Hematol
Title: A genetically myeloablated MPS VII model detects the expansion and curative properties of as few as 100 enriched murine stem cells.
Volume: 27
Issue: 11
Pages: 1691-704
Publication
First Author: Meng XL
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Induced pluripotent stem cells derived from mouse models of lysosomal storage disorders.
Volume: 107
Issue: 17
Pages: 7886-91
Publication
First Author: Bartolomeo R
Year: 2017
Journal: J Clin Invest
Title: mTORC1 hyperactivation arrests bone growth in lysosomal storage disorders by suppressing autophagy.
Volume: 127
Issue: 10
Pages: 3717-3729
Publication
First Author: Majumder M
Year: 2016
Journal: Stem Cells
Title: COX-2 Induces Breast Cancer Stem Cells via EP4/PI3K/AKT/NOTCH/WNT Axis.
Volume: 34
Issue: 9
Pages: 2290-305
Publication
First Author: Gwynn B
Year: 1998
Journal: Mol Cell Biol
Title: Intracisternal A-particle element transposition into the murine beta-glucuronidase gene correlates with loss of enzyme activity: a new model for beta-glucuronidase deficiency in the C3H mouse.
Volume: 18
Issue: 11
Pages: 6474-81
Publication  
First Author: Nguyen QH
Year: 2020
Journal: Sci Transl Med
Title: Tolerance induction and microglial engraftment after fetal therapy without conditioning in mice with Mucopolysaccharidosis type VII.
Volume: 12
Issue: 532
Publication
First Author: Li B
Year: 2006
Journal: FASEB J
Title: VEGF and PlGF promote adult vasculogenesis by enhancing EPC recruitment and vessel formation at the site of tumor neovascularization.
Volume: 20
Issue: 9
Pages: 1495-7