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Search results 1 to 100 out of 301 for Nras

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Category: Publication
Type Details Score
Publication
First Author: Chang HY
Year: 1987
Journal: Oncogene Res
Title: Mouse N-ras genes: organization of the functional locus and of a truncated cDNA-like pseudogene.
Volume: 1
Issue: 2
Pages: 129-36
Publication
First Author: Burd CE
Year: 2014
Journal: Cancer Discov
Title: Mutation-specific RAS oncogenicity explains NRAS codon 61 selection in melanoma.
Volume: 4
Issue: 12
Pages: 1418-29
Publication
First Author: Takahashi C
Year: 2006
Journal: Nat Genet
Title: Nras loss induces metastatic conversion of Rb1-deficient neuroendocrine thyroid tumor.
Volume: 38
Issue: 1
Pages: 118-23
Publication
First Author: Murphy BM
Year: 2022
Journal: Nat Commun
Title: Enhanced BRAF engagement by NRAS mutants capable of promoting melanoma initiation.
Volume: 13
Issue: 1
Pages: 3153
Publication
First Author: Kwong LN
Year: 2012
Journal: Nat Med
Title: Oncogenic NRAS signaling differentially regulates survival and proliferation in melanoma.
Volume: 18
Issue: 10
Pages: 1503-10
Publication
First Author: Wiesner SM
Year: 2005
Journal: Blood
Title: Repressible transgenic model of NRAS oncogene-driven mast cell disease in the mouse.
Volume: 106
Issue: 3
Pages: 1054-62
Publication
First Author: Kong G
Year: 2016
Journal: Leukemia
Title: The ability of endogenous Nras oncogenes to initiate leukemia is codon-dependent.
Volume: 30
Issue: 9
Pages: 1935-8
Publication
First Author: Lassen LB
Year: 2012
Journal: PLoS One
Title: Nras overexpression results in granulocytosis, T-cell expansion and early lethality in mice.
Volume: 7
Issue: 8
Pages: e42216
Publication
First Author: Ballarín-González B
Year: 2013
Journal: PLoS One
Title: Deregulated Nras expression in knock-in animals harboring a gammaretroviral long terminal repeat at the Nras/Csde1 locus.
Volume: 8
Issue: 2
Pages: e56029
Publication
First Author: Li Q
Year: 2013
Journal: Nature
Title: Oncogenic Nras has bimodal effects on stem cells that sustainably increase competitiveness.
Volume: 504
Issue: 7478
Pages: 143-147
Publication
First Author: Pawlikowski JS
Year: 2015
Journal: J Invest Dermatol
Title: Acute Inhibition of MEK Suppresses Congenital Melanocytic Nevus Syndrome in a Murine Model Driven by Activated NRAS and Wnt Signaling.
Volume: 135
Issue: 8
Pages: 2093-2101
Publication
First Author: Kunimoto H
Year: 2018
Journal: Cancer Cell
Title: Cooperative Epigenetic Remodeling by TET2 Loss and NRAS Mutation Drives Myeloid Transformation and MEK Inhibitor Sensitivity.
Volume: 33
Issue: 1
Pages: 44-59.e8
Publication
First Author: Wang J
Year: 2011
Journal: Blood
Title: Endogenous oncogenic Nras mutation initiates hematopoietic malignancies in a dose- and cell type-dependent manner.
Volume: 118
Issue: 2
Pages: 368-79
Publication
First Author: Shi X
Year: 2019
Journal: BMC Cancer
Title: Cooperation of Dnmt3a R878H with Nras G12D promotes leukemogenesis in knock-in mice: a pilot study.
Volume: 19
Issue: 1
Pages: 1072
Publication  
First Author: Rajagopalan A
Year: 2023
Journal: J Clin Invest
Title: A gain-of-function p53 mutant synergizes with oncogenic NRAS to promote acute myeloid leukemia in mice.
Volume: 133
Issue: 24
Publication
First Author: Wen Z
Year: 2021
Journal: Blood
Title: Nras Q61R/+ and Kras-/- cooperate to downregulate Rasgrp1 and promote lympho-myeloid leukemia in early T-cell precursors.
Volume: 137
Issue: 23
Pages: 3259-3271
Publication
First Author: Pedersen M
Year: 2013
Journal: Cancer Discov
Title: Primary melanoma of the CNS in children is driven by congenital expression of oncogenic NRAS in melanocytes.
Volume: 3
Issue: 4
Pages: 458-469
Publication
First Author: Wang J
Year: 2010
Journal: Blood
Title: Endogenous oncogenic Nras mutation promotes aberrant GM-CSF signaling in granulocytic/monocytic precursors in a murine model of chronic myelomonocytic leukemia.
Volume: 116
Issue: 26
Pages: 5991-6002
Publication
First Author: You X
Year: 2022
Journal: Blood
Title: Asxl1 loss cooperates with oncogenic Nras in mice to reprogram the immune microenvironment and drive leukemic transformation.
Volume: 139
Issue: 7
Pages: 1066-1079
Publication
First Author: Fuentes-Mateos R
Year: 2019
Journal: Cell Death Dis
Title: Concomitant deletion of HRAS and NRAS leads to pulmonary immaturity, respiratory failure and neonatal death in mice.
Volume: 10
Issue: 11
Pages: 838
Publication
First Author: Guerrero I
Year: 1985
Journal: Proc Natl Acad Sci U S A
Title: Loss of the normal N-ras allele in a mouse thymic lymphoma induced by a chemical carcinogen.
Volume: 82
Issue: 23
Pages: 7810-4
Publication
First Author: Coleman DJ
Year: 2015
Journal: Mol Cancer Res
Title: Loss of keratinocytic RXRα combined with activated CDK4 or oncogenic NRAS generates UVB-induced melanomas via loss of p53 and PTEN in the tumor microenvironment.
Volume: 13
Issue: 1
Pages: 186-96
Publication
First Author: Giannou AD
Year: 2017
Journal: EMBO Mol Med
Title: NRAS destines tumor cells to the lungs.
Volume: 9
Issue: 5
Pages: 672-686
Publication  
First Author: Ragab N
Year: 2021
Journal: Int J Mol Sci
Title: Oncogenic NRAS Accelerates Rhabdomyosarcoma Formation When Occurring within a Specific Time Frame during Tumor Development in Mice.
Volume: 22
Issue: 24
Publication
First Author: Kong G
Year: 2016
Journal: Leukemia
Title: Loss of wild-type Kras promotes activation of all Ras isoforms in oncogenic Kras-induced leukemogenesis.
Volume: 30
Issue: 7
Pages: 1542-51
Publication
First Author: Kim WI
Year: 2009
Journal: Blood
Title: RAS oncogene suppression induces apoptosis followed by more differentiated and less myelosuppressive disease upon relapse of acute myeloid leukemia.
Volume: 113
Issue: 5
Pages: 1086-96
Publication
First Author: Mangues R
Year: 1990
Journal: Oncogene
Title: Tumorigenesis and male sterility in transgenic mice expressing a MMTV/N-ras oncogene.
Volume: 5
Issue: 10
Pages: 1491-7
Publication
First Author: Mangues R
Year: 1992
Journal: Oncogene
Title: Overexpression of the N-ras proto-oncogene, not somatic mutational activation, associated with malignant tumors in transgenic mice.
Volume: 7
Issue: 10
Pages: 2073-6
Publication
First Author: Mangues R
Year: 1998
Journal: Cancer Res
Title: Antitumor effect of a farnesyl protein transferase inhibitor in mammary and lymphoid tumors overexpressing N-ras in transgenic mice.
Volume: 58
Issue: 6
Pages: 1253-9
Publication
First Author: Mediavilla MD
Year: 1997
Journal: J Pineal Res
Title: Effects of melatonin on mammary gland lesions in transgenic mice overexpressing N-ras proto-oncogene.
Volume: 22
Issue: 2
Pages: 86-94
Publication  
First Author: Dorard C
Year: 2017
Journal: Nat Commun
Title: RAF proteins exert both specific and compensatory functions during tumour progression of NRAS-driven melanoma.
Volume: 8
Pages: 15262
Publication
First Author: You X
Year: 2018
Journal: Blood
Title: Unique dependence on Sos1 in Kras G12D -induced leukemogenesis.
Volume: 132
Issue: 24
Pages: 2575-2579
Publication
First Author: Assenmacher CA
Year: 2021
Journal: J Histochem Cytochem
Title: Classification and Grading of Melanocytic Lesions in a Mouse Model of NRAS-driven Melanomagenesis.
Volume: 69
Issue: 3
Pages: 203-218
Publication
First Author: Li A
Year: 2012
Journal: J Invest Dermatol
Title: Activated mutant NRas(Q61K) drives aberrant melanocyte signaling, survival, and invasiveness via a Rac1-dependent mechanism.
Volume: 132
Issue: 11
Pages: 2610-21
Publication
First Author: Wang Y
Year: 2013
Journal: Cancer Discov
Title: Mutant N-RAS protects colorectal cancer cells from stress-induced apoptosis and contributes to cancer development and progression.
Volume: 3
Issue: 3
Pages: 294-307
Publication
First Author: Wang J
Year: 2013
Journal: Blood
Title: Nras(G12D/+) promotes leukemogenesis by aberrantly regulating hematopoietic stem cell functions.
Volume: 121
Issue: 26
Pages: 5203-7
Publication  
First Author: Campagne C
Year: 2017
Journal: Cell Signal
Title: RACK1 cooperates with NRASQ61K to promote melanoma in vivo.
Volume: 36
Pages: 255-266
Publication
First Author: Souroullas GP
Year: 2016
Journal: Nat Med
Title: An oncogenic Ezh2 mutation induces tumors through global redistribution of histone 3 lysine 27 trimethylation.
Volume: 22
Issue: 6
Pages: 632-40
Publication
First Author: Xu J
Year: 2013
Journal: Cancer Discov
Title: Dominant role of oncogene dosage and absence of tumor suppressor activity in Nras-driven hematopoietic transformation.
Volume: 3
Issue: 9
Pages: 993-1001
Publication
First Author: Burgess MR
Year: 2014
Journal: Blood
Title: Preclinical efficacy of MEK inhibition in Nras-mutant AML.
Volume: 124
Issue: 26
Pages: 3947-55
Publication
First Author: Li Q
Year: 2011
Journal: Blood
Title: Hematopoiesis and leukemogenesis in mice expressing oncogenic NrasG12D from the endogenous locus.
Volume: 117
Issue: 6
Pages: 2022-32
Publication
First Author: Kong G
Year: 2014
Journal: J Clin Invest
Title: Combined MEK and JAK inhibition abrogates murine myeloproliferative neoplasm.
Volume: 124
Issue: 6
Pages: 2762-73
Publication
First Author: Zambetti NA
Year: 2020
Journal: Blood
Title: Genetic disruption of N-RasG12D palmitoylation perturbs hematopoiesis and prevents myeloid transformation in mice.
Volume: 135
Issue: 20
Pages: 1772-1782
Publication  
First Author: Dong Y
Year: 2019
Journal: Cells
Title: Synergy of NUP98-HOXA10 Fusion Gene and NrasG12D Mutation Preserves the Stemness of Hematopoietic Stem Cells on Culture Condition.
Volume: 8
Issue: 9
Publication
First Author: Rahman H
Year: 2021
Journal: J Invest Dermatol
Title: Aspirin Protects Melanocytes and Keratinocytes against UVB-Induced DNA Damage In Vivo.
Volume: 141
Issue: 1
Pages: 132-141.e3
Publication
First Author: Buchberg AM
Year: 1989
Journal: Genomics
Title: Localization of the murine macrophage colony-stimulating factor gene to chromosome 3 using interspecific backcross analysis.
Volume: 5
Issue: 2
Pages: 363-7
Publication
First Author: Slape C
Year: 2008
Journal: Blood
Title: Leukemic transformation in mice expressing a NUP98-HOXD13 transgene is accompanied by spontaneous mutations in Nras, Kras, and Cbl.
Volume: 112
Issue: 5
Pages: 2017-9
Publication  
First Author: Newlaczyl AU
Year: 2017
Journal: Sci Rep
Title: Quantification of spatiotemporal patterns of Ras isoform expression during development.
Volume: 7
Pages: 41297
Publication
First Author: Haigis KM
Year: 2008
Journal: Nat Genet
Title: Differential effects of oncogenic K-Ras and N-Ras on proliferation, differentiation and tumor progression in the colon.
Volume: 40
Issue: 5
Pages: 600-8
Publication
First Author: Lyons PA
Year: 2001
Journal: Diabetes
Title: Mapping by genetic interaction: high-resolution congenic mapping of the type 1 diabetes loci Idd10 and Idd18 in the NOD mouse.
Volume: 50
Issue: 11
Pages: 2633-7
Publication
First Author: Choi YS
Year: 2022
Journal: Cell
Title: Topical therapy for regression and melanoma prevention of congenital giant nevi.
Volume: 185
Issue: 12
Pages: 2071-2085.e12
Publication
First Author: Weyandt JD
Year: 2016
Journal: PLoS One
Title: Isoform-Specific Effects of Wild-Type Ras Genes on Carcinogen-Induced Lung Tumorigenesis in Mice.
Volume: 11
Issue: 12
Pages: e0167205
Publication
First Author: Chang YI
Year: 2015
Journal: Leukemia
Title: Loss of Dnmt3a and endogenous Kras(G12D/+) cooperate to regulate hematopoietic stem and progenitor cell functions in leukemogenesis.
Volume: 29
Issue: 9
Pages: 1847-56
Publication
First Author: Dovey OM
Year: 2017
Journal: Blood
Title: Molecular synergy underlies the co-occurrence patterns and phenotype of NPM1-mutant acute myeloid leukemia.
Volume: 130
Issue: 17
Pages: 1911-1922
Publication
First Author: Zhang J
Year: 2017
Journal: Blood
Title: p53-/- synergizes with enhanced NrasG12D signaling to transform megakaryocyte-erythroid progenitors in acute myeloid leukemia.
Volume: 129
Issue: 3
Pages: 358-370
Publication
First Author: Nowacka JD
Year: 2016
Journal: Oncotarget
Title: MEK1 is required for the development of NRAS-driven leukemia.
Volume: 7
Issue: 49
Pages: 80113-80130
Publication
First Author: Threadgill DS
Year: 1994
Journal: Genomics
Title: Syntenic assignment of human chromosome 1 homologous loci in the bovine.
Volume: 22
Issue: 3
Pages: 626-30
Publication
First Author: van Tuyn J
Year: 2017
Journal: J Invest Dermatol
Title: Oncogene-Expressing Senescent Melanocytes Up-Regulate MHC Class II, a Candidate Melanoma Suppressor Function.
Volume: 137
Issue: 10
Pages: 2197-2207
Publication
First Author: Gu Z
Year: 2019
Journal: Cancer Discov
Title: Loss of EZH2 Reprograms BCAA Metabolism to Drive Leukemic Transformation.
Volume: 9
Issue: 9
Pages: 1228-1247
Publication
First Author: Ha L
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: ARF functions as a melanoma tumor suppressor by inducing p53-independent senescence.
Volume: 104
Issue: 26
Pages: 10968-73
Publication
First Author: Chen S
Year: 2022
Journal: Cancer Discov
Title: Impaired Proteolysis of Noncanonical RAS Proteins Drives Clonal Hematopoietic Transformation.
Volume: 12
Issue: 10
Pages: 2434-2453
Publication
First Author: To MD
Year: 2013
Journal: Oncogene
Title: Interactions between wild-type and mutant Ras genes in lung and skin carcinogenesis.
Volume: 32
Issue: 34
Pages: 4028-33
Publication
First Author: Wen Z
Year: 2022
Journal: Leukemia
Title: Tcof1 haploinsufficiency promotes early T cell precursor-like leukemia in NrasQ61R/+ mice.
Volume: 36
Issue: 4
Pages: 1167-1170
Publication
First Author: Halaban R
Year: 2016
Journal: J Invest Dermatol
Title: RASopathy Gene Mutations in Melanoma.
Volume: 136
Issue: 9
Pages: 1755-9
Publication
First Author: Umanoff H
Year: 1995
Journal: Proc Natl Acad Sci U S A
Title: The murine N-ras gene is not essential for growth and development.
Volume: 92
Issue: 5
Pages: 1709-13
Publication
First Author: Diaz R
Year: 2004
Journal: Carcinogenesis
Title: Complex effects of Ras proto-oncogenes in tumorigenesis.
Volume: 25
Issue: 4
Pages: 535-9
Publication
First Author: Pérez de Castro I
Year: 2003
Journal: Cancer Res
Title: Mice deficient for N-ras: impaired antiviral immune response and T-cell function.
Volume: 63
Issue: 7
Pages: 1615-22
Publication
First Author: Carr RM
Year: 2021
Journal: Nat Commun
Title: RAS mutations drive proliferative chronic myelomonocytic leukemia via a KMT2A-PLK1 axis.
Volume: 12
Issue: 1
Pages: 2901
Publication
First Author: Abdallah MG
Year: 2021
Journal: Leukemia
Title: RUNX1-ETO (RUNX1-RUNX1T1) induces myeloid leukemia in mice in an age-dependent manner.
Volume: 35
Issue: 10
Pages: 2983-2988
Publication
First Author: Fenouille N
Year: 2017
Journal: Nat Med
Title: The creatine kinase pathway is a metabolic vulnerability in EVI1-positive acute myeloid leukemia.
Volume: 23
Issue: 3
Pages: 301-313
Publication
First Author: Liu J
Year: 2010
Journal: J Biol Chem
Title: MicroRNA-214 promotes myogenic differentiation by facilitating exit from mitosis via down-regulation of proto-oncogene N-ras.
Volume: 285
Issue: 34
Pages: 26599-607
Publication
First Author: Wolfman JC
Year: 2002
Journal: Mol Cell Biol
Title: Cellular N-Ras promotes cell survival by downregulation of Jun N-terminal protein kinase and p38.
Volume: 22
Issue: 5
Pages: 1589-606
Publication
First Author: Shimizu K
Year: 1983
Journal: Proc Natl Acad Sci U S A
Title: Three human transforming genes are related to the viral ras oncogenes.
Volume: 80
Issue: 8
Pages: 2112-6
Publication
First Author: Ryan J
Year: 1984
Journal: Nucleic Acids Res
Title: Molecular cloning and chromosome assignment of murine N-ras.
Volume: 12
Issue: 15
Pages: 6063-72
Publication
First Author: Guerrero I
Year: 1984
Journal: Science
Title: Isolation, characterization, and chromosome assignment of mouse N-ras gene from carcinogen-induced thymic lymphoma.
Volume: 225
Issue: 4666
Pages: 1041-3
Publication
First Author: Cases S
Year: 1992
Journal: Oncogene
Title: Inactivation of the murine N-ras gene by gene targeting.
Volume: 7
Issue: 12
Pages: 2525-8
Publication
First Author: Song SP
Year: 2013
Journal: Biochem J
Title: Ras palmitoylation is necessary for N-Ras activation and signal propagation in growth factor signalling.
Volume: 454
Issue: 2
Pages: 323-32
Publication
First Author: Jeffers M
Year: 1990
Journal: Nucleic Acids Res
Title: Characterization of unr; a gene closely linked to N-ras.
Volume: 18
Issue: 16
Pages: 4891-9
Publication
First Author: Tsukamoto S
Year: 2006
Journal: Biochem Biophys Res Commun
Title: Oog1, an oocyte-specific protein, interacts with Ras and Ras-signaling proteins during early embryogenesis.
Volume: 343
Issue: 4
Pages: 1105-12
Publication
First Author: Hinman MN
Year: 2014
Journal: Mol Cell Biol
Title: Neurofibromatosis type 1 alternative splicing is a key regulator of Ras signaling in neurons.
Volume: 34
Issue: 12
Pages: 2188-97
Publication
First Author: Iborra S
Year: 2013
Journal: J Exp Med
Title: N-ras couples antigen receptor signaling to Eomesodermin and to functional CD8+ T cell memory but not to effector differentiation.
Volume: 210
Issue: 7
Pages: 1463-79
Publication
First Author: Damnernsawad A
Year: 2016
Journal: Stem Cells
Title: Kras is Required for Adult Hematopoiesis.
Volume: 34
Issue: 7
Pages: 1859-71
Publication
First Author: Villatoro A
Year: 2023
Journal: Nat Commun
Title: Endogenous IL-1 receptor antagonist restricts healthy and malignant myeloproliferation.
Volume: 14
Issue: 1
Pages: 12
Publication
First Author: Liu P
Year: 2016
Journal: Leukemia
Title: Palmitoylacyltransferase Zdhhc9 inactivation mitigates leukemogenic potential of oncogenic Nras.
Volume: 30
Issue: 5
Pages: 1225-8
Publication
First Author: Ney GM
Year: 2021
Journal: Cancer Res
Title: Oncogenic N-Ras Mitigates Oxidative Stress-Induced Apoptosis of Hematopoietic Stem Cells.
Volume: 81
Issue: 5
Pages: 1240-1251
Publication
First Author: Pulikkan JA
Year: 2018
Journal: Cell
Title: CBFβ-SMMHC Inhibition Triggers Apoptosis by Disrupting MYC Chromatin Dynamics in Acute Myeloid Leukemia.
Volume: 174
Issue: 1
Pages: 172-186.e21
Publication
First Author: Sutter C
Year: 1993
Journal: Mol Carcinog
Title: ras gene activation and aberrant expression of keratin K13 in ultraviolet B radiation-induced epidermal neoplasias of mouse skin.
Volume: 8
Issue: 1
Pages: 13-9
Publication
First Author: Mor A
Year: 2008
Journal: Eur J Immunol
Title: N-Ras or K-Ras inhibition increases the number and enhances the function of Foxp3 regulatory T cells.
Volume: 38
Issue: 6
Pages: 1493-502
Publication
First Author: Jin X
Year: 2018
Journal: Blood Adv
Title: Oncogenic N-Ras and Tet2 haploinsufficiency collaborate to dysregulate hematopoietic stem and progenitor cells.
Volume: 2
Issue: 11
Pages: 1259-1271
Publication
First Author: Lissanu Deribe Y
Year: 2016
Journal: Small GTPases
Title: Interplay between PREX2 mutations and the PI3K pathway and its effect on epigenetic regulation of gene expression in NRAS-mutant melanoma.
Volume: 7
Issue: 3
Pages: 178-85
Publication
First Author: Liu Y
Year: 2021
Journal: Nat Commun
Title: Convergence of oncogenic cooperation at single-cell and single-gene levels drives leukemic transformation.
Volume: 12
Issue: 1
Pages: 6323
Publication
First Author: Esteban LM
Year: 2001
Journal: Mol Cell Biol
Title: Targeted genomic disruption of H-ras and N-ras, individually or in combination, reveals the dispensability of both loci for mouse growth and development.
Volume: 21
Issue: 5
Pages: 1444-52
Publication
First Author: Xue L
Year: 2014
Journal: Blood
Title: NrasG12D oncoprotein inhibits apoptosis of preleukemic cells expressing Cbfβ-SMMHC via activation of MEK/ERK axis.
Volume: 124
Issue: 3
Pages: 426-36
Publication
First Author: López-Fernández LA
Year: 1995
Journal: Biochim Biophys Acta
Title: Different developmental pattern of N-ras and unr gene expression in mouse gametogenic and somatic tissues.
Volume: 1263
Issue: 1
Pages: 10-6
Publication
First Author: Ganter B
Year: 1997
Journal: Oncogene
Title: Myb binding sites within the N-ras promoter repress transcription.
Volume: 15
Issue: 2
Pages: 193-202
Publication
First Author: Martínez-Salgado C
Year: 2006
Journal: Exp Cell Res
Title: Involvement of H- and N-Ras isoforms in transforming growth factor-beta1-induced proliferation and in collagen and fibronectin synthesis.
Volume: 312
Issue: 11
Pages: 2093-106
Publication
First Author: Groner B
Year: 1987
Journal: Trends Genet
Title: Targeted expression of the ras and myc oncogenes in transgenic mice
Volume: 3
Issue: 11
Pages: 306-9
Publication
First Author: Kim E
Year: 1999
Journal: J Biol Chem
Title: Disruption of the mouse Rce1 gene results in defective Ras processing and mislocalization of Ras within cells.
Volume: 274
Issue: 13
Pages: 8383-90
Publication
First Author: Anastasaki C
Year: 2014
Journal: Hum Mol Genet
Title: Neuronal NF1/RAS regulation of cyclic AMP requires atypical PKC activation.
Volume: 23
Issue: 25
Pages: 6712-21
Publication
First Author: Bender RH
Year: 2015
Journal: Stem Cells
Title: Activated k-ras, but not h-ras or N-ras, regulates brain neural stem cell proliferation in a raf/rb-dependent manner.
Volume: 33
Issue: 6
Pages: 1998-2010