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Search results 1 to 100 out of 123 for Ptpn2

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Category: Publication
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Type Details Score
Publication
24445916 | J:206438
 
First Author: Wiede F
Year: 2014
Journal: Nat Commun
Title: PTPN2 attenuates T-cell lymphopenia-induced proliferation.
Volume: 5
Pages: 3073
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Publication
33055428 | J:301817
 
First Author: Hsieh WC
Year: 2020
Journal: JCI Insight
Title: PTPN2 links colonic and joint inflammation in experimental autoimmune arthritis.
Volume: 5
Issue: 20
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Publication
28798028 | J:244288
First Author: Wiede F
Year: 2017
Journal: J Exp Med
Title: PTPN2 regulates T cell lineage commitment and αβ versus γδ specification.
Volume: 214
Issue: 9
Pages: 2733-2758
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Publication
31527834 | J:292891
First Author: LaFleur MW
Year: 2019
Journal: Nat Immunol
Title: PTPN2 regulates the generation of exhausted CD8+ T cell subpopulations and restrains tumor immunity.
Volume: 20
Issue: 10
Pages: 1335-1347
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Publication
20473312 | J:162251
First Author: Kleppe M
Year: 2010
Journal: Nat Genet
Title: Deletion of the protein tyrosine phosphatase gene PTPN2 in T-cell acute lymphoblastic leukemia.
Volume: 42
Issue: 6
Pages: 530-5
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Publication
29444435 | J:271086
First Author: Spalinger MR
Year: 2018
Journal: Cell Rep
Title: PTPN2 Regulates Inflammasome Activation and Controls Onset of Intestinal Inflammation and Colon Cancer.
Volume: 22
Issue: 7
Pages: 1835-1848
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Publication
30936146 | J:276219
First Author: Wiede F
Year: 2019
Journal: Diabetes
Title: T-Cell-Specific PTPN2 Deficiency in NOD Mice Accelerates the Development of Type 1 Diabetes and Autoimmune Comorbidities.
Volume: 68
Issue: 6
Pages: 1251-1266
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Publication
30620725 | J:295241
First Author: Svensson MN
Year: 2019
Journal: J Clin Invest
Title: Reduced expression of phosphatase PTPN2 promotes pathogenic conversion of Tregs in autoimmunity.
Volume: 129
Issue: 3
Pages: 1193-1210
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Publication
25492475 | J:277355
First Author: Spalinger MR
Year: 2015
Journal: Mucosal Immunol
Title: PTPN2 controls differentiation of CD4⁺ T cells and limits intestinal inflammation and intestinal dysbiosis.
Volume: 8
Issue: 4
Pages: 918-29
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Publication
32726622 | J:300934
First Author: Flosbach M
Year: 2020
Journal: Cell Rep
Title: PTPN2 Deficiency Enhances Programmed T Cell Expansion and Survival Capacity of Activated T Cells.
Volume: 32
Issue: 4
Pages: 107957
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Publication
30955247 | J:295581
First Author: Li Y
Year: 2019
Journal: J Cell Mol Med
Title: PTPN2 improved renal injury and fibrosis by suppressing STAT-induced inflammation in early diabetic nephropathy.
Volume: 23
Issue: 6
Pages: 4179-4195
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Publication
37030630 | J:337238
First Author: Canale V
Year: 2023
Journal: Cell Mol Gastroenterol Hepatol
Title: PTPN2 Is a Critical Regulator of Ileal Paneth Cell Viability and Function in Mice.
Volume: 16
Issue: 1
Pages: 39-62
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Publication
35196085 | J:321794
First Author: Goh PK
Year: 2022
Journal: Sci Adv
Title: PTPN2 elicits cell autonomous and non-cell autonomous effects on antitumor immunity in triple-negative breast cancer.
Volume: 8
Issue: 8
Pages: eabk3338
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Publication
33914023 | J:343869
 
First Author: Hochheiser K
Year: 2021
Journal: J Exp Med
Title: Ptpn2 and KLRG1 regulate the generation and function of tissue-resident memory CD8+ T cells in skin.
Volume: 218
Issue: 6
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Publication
31803974 | J:283878
First Author: Wiede F
Year: 2020
Journal: EMBO J
Title: PTPN2 phosphatase deletion in T cells promotes anti-tumour immunity and CAR T-cell efficacy in solid tumours.
Volume: 39
Issue: 2
Pages: e103637
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Publication
32652144 | J:305661
First Author: Spalinger MR
Year: 2020
Journal: Gastroenterology
Title: PTPN2 Regulates Interactions Between Macrophages and Intestinal Epithelial Cells to Promote Intestinal Barrier Function.
Volume: 159
Issue: 5
Pages: 1763-1777.e14
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Publication
29587266 | J:318495
First Author: Li Y
Year: 2018
Journal: Cell Physiol Biochem
Title: Overexpression of PTPN2 in Visceral Adipose Tissue Ameliorated Atherosclerosis via T Cells Polarization Shift in Diabetic Apoe-/- Mice.
Volume: 46
Issue: 1
Pages: 118-132
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Publication
33330862 | J:300213
     
First Author: Spalinger MR
Year: 2020
Journal: bioRxiv
Title: Identification of a Novel Susceptibility Marker for SARS-CoV-2 Infection in Human Subjects and Risk Mitigation with a Clinically Approved JAK Inhibitor in Human/Mouse Cells.
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30971695 | J:285513
First Author: LaFleur MW
Year: 2019
Journal: Nat Commun
Title: A CRISPR-Cas9 delivery system for in vivo screening of genes in the immune system.
Volume: 10
Issue: 1
Pages: 1668
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Publication
22080863 | J:184426
First Author: Wiede F
Year: 2011
Journal: J Clin Invest
Title: T cell protein tyrosine phosphatase attenuates T cell signaling to maintain tolerance in mice.
Volume: 121
Issue: 12
Pages: 4758-74
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34623320 | J:320663
 
First Author: Marchelletta RR
Year: 2021
Journal: J Clin Invest
Title: T cell protein tyrosine phosphatase protects intestinal barrier function by restricting epithelial tight junction remodeling.
Volume: 131
Issue: 17
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Publication
34201918 | J:314471
 
First Author: Hering L
Year: 2021
Journal: Int J Mol Sci
Title: Macrophages Compensate for Loss of Protein Tyrosine Phosphatase N2 in Dendritic Cells to Protect from Elevated Colitis.
Volume: 22
Issue: 13
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Publication
32973765 | J:298998
 
First Author: Hering L
Year: 2020
Journal: Front Immunol
Title: Protein Tyrosine Phosphatase Non-Receptor Type 2 Function in Dendritic Cells Is Crucial to Maintain Tissue Tolerance.
Volume: 11
Pages: 1856
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Publication
20111595 | J:157623
First Author: Hassan SW
Year: 2010
Journal: PLoS One
Title: Increased susceptibility to dextran sulfate sodium induced colitis in the T cell protein tyrosine phosphatase heterozygous mouse.
Volume: 5
Issue: 1
Pages: e8868
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30890796 | J:282432
First Author: Twohig JP
Year: 2019
Journal: Nat Immunol
Title: Activation of naïve CD4+ T cells re-tunes STAT1 signaling to deliver unique cytokine responses in memory CD4+ T cells.
Volume: 20
Issue: 4
Pages: 458-470
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34420044 | J:321779
First Author: Spalinger MR
Year: 2022
Journal: Mucosal Immunol
Title: Loss of protein tyrosine phosphatase non-receptor type 2 reduces IL-4-driven alternative macrophage activation.
Volume: 15
Issue: 1
Pages: 74-83
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Publication
24954415 | J:215484
First Author: Gurzov EN
Year: 2014
Journal: Cell Metab
Title: Hepatic oxidative stress promotes insulin-STAT-5 signaling and obesity by inactivating protein tyrosine phosphatase N2.
Volume: 20
Issue: 1
Pages: 85-102
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Publication
33001862 | J:302090
 
First Author: Katkeviciute E
Year: 2021
Journal: J Clin Invest
Title: Protein tyrosine phosphatase nonreceptor type 2 controls colorectal cancer development.
Volume: 131
Issue: 1
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Publication
1731319 | J:1925
First Author: Mosinger B Jr
Year: 1992
Journal: Proc Natl Acad Sci U S A
Title: Cloning and characterization of a mouse cDNA encoding a cytoplasmic protein-tyrosine-phosphatase.
Volume: 89
Issue: 2
Pages: 499-503
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1283199 | J:3913
First Author: Miyasaka H
Year: 1992
Journal: Mol Cell Biochem
Title: Molecular cloning, nucleotide sequence and expression of a cDNA encoding an intracellular protein tyrosine phosphatase, PTPase-2, from mouse testis and T-cells.
Volume: 118
Issue: 1
Pages: 91-8
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9271584 | J:42595
First Author: You-Ten KE
Year: 1997
Journal: J Exp Med
Title: Impaired bone marrow microenvironment and immune function in T cell protein tyrosine phosphatase-deficient mice.
Volume: 186
Issue: 5
Pages: 683-93
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11909529 | J:115366
First Author: Simoncic PD
Year: 2002
Journal: Curr Biol
Title: The T cell protein tyrosine phosphatase is a negative regulator of janus family kinases 1 and 3.
Volume: 12
Issue: 6
Pages: 446-53
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14726372 | J:90541
First Author: Heinonen KM
Year: 2004
Journal: Blood
Title: T-cell protein tyrosine phosphatase deletion results in progressive systemic inflammatory disease.
Volume: 103
Issue: 9
Pages: 3457-64
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15696169 | J:96360
First Author: van Vliet C
Year: 2005
Journal: Nat Immunol
Title: Selective regulation of tumor necrosis factor-induced Erk signaling by Src family kinases and the T cell protein tyrosine phosphatase.
Volume: 6
Issue: 3
Pages: 253-60
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Publication
20484139 | J:169644
First Author: Fukushima A
Year: 2010
Journal: Diabetes
Title: T-cell protein tyrosine phosphatase attenuates STAT3 and insulin signaling in the liver to regulate gluconeogenesis.
Volume: 59
Issue: 8
Pages: 1906-14
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Publication
22124607 | J:181775
First Author: Loh K
Year: 2012
Journal: Diabetologia
Title: T cell protein tyrosine phosphatase (TCPTP) deficiency in muscle does not alter insulin signalling and glucose homeostasis in mice.
Volume: 55
Issue: 2
Pages: 468-78
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22590589 | J:186843
First Author: Wiede F
Year: 2012
Journal: PLoS One
Title: Strain-dependent differences in bone development, myeloid hyperplasia, morbidity and mortality in ptpn2-deficient mice.
Volume: 7
Issue: 5
Pages: e36703
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Publication
28322331 | J:241363
 
First Author: Lee H
Year: 2017
Journal: Sci Rep
Title: Targeted disruption of TC-PTP in the proliferative compartment augments STAT3 and AKT signaling and skin tumor development.
Volume: 7
Pages: 45077
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17234741 | J:141675
First Author: Bourdeau A
Year: 2007
Journal: Blood
Title: TC-PTP-deficient bone marrow stromal cells fail to support normal B lymphopoiesis due to abnormal secretion of interferon-{gamma}.
Volume: 109
Issue: 10
Pages: 4220-8
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12847239 | J:123459
First Author: Dupuis M
Year: 2003
Journal: J Immunol
Title: Gr-1+ myeloid cells lacking T cell protein tyrosine phosphatase inhibit lymphocyte proliferation by an IFN-gamma- and nitric oxide-dependent mechanism.
Volume: 171
Issue: 2
Pages: 726-32
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1733852 | J:1926
First Author: Sakaguchi AY
Year: 1992
Journal: Genomics
Title: Assignment of tyrosine-specific T-cell phosphatase to conserved syntenic groups on human chromosome 18 and mouse chromosome 18.
Volume: 12
Issue: 1
Pages: 151-4
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8534367 | J:30331
First Author: Reddy RS
Year: 1995
Journal: DNA Cell Biol
Title: Alternative splicing generates four different forms of a non-transmembrane protein tyrosine phosphatase mRNA.
Volume: 14
Issue: 12
Pages: 1007-15
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31509751 | J:281006
First Author: Dodd GT
Year: 2019
Journal: Cell Rep
Title: Intranasal Targeting of Hypothalamic PTP1B and TCPTP Reinstates Leptin and Insulin Sensitivity and Promotes Weight Loss in Obesity.
Volume: 28
Issue: 11
Pages: 2905-2922.e5
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23135963 | J:194693
First Author: Bourdeau A
Year: 2013
Journal: Stem Cells
Title: Inhibition of T cell protein tyrosine phosphatase enhances interleukin-18-dependent hematopoietic stem cell expansion.
Volume: 31
Issue: 2
Pages: 293-304
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19474293 | J:150081
First Author: Heinonen KM
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Protein tyrosine phosphatases PTP-1B and TC-PTP play nonredundant roles in macrophage development and IFN-gamma signaling.
Volume: 106
Issue: 23
Pages: 9368-72
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22252315 | J:183709
First Author: Zee T
Year: 2012
Journal: Mol Cell Biol
Title: T-cell protein tyrosine phosphatase regulates bone resorption and whole-body insulin sensitivity through its expression in osteoblasts.
Volume: 32
Issue: 6
Pages: 1080-8
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Publication
21216966 | J:219081
First Author: Bettaieb A
Year: 2011
Journal: J Biol Chem
Title: Differential regulation of endoplasmic reticulum stress by protein tyrosine phosphatase 1B and T cell protein tyrosine phosphatase.
Volume: 286
Issue: 11
Pages: 9225-35
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15632081 | J:96001
First Author: Galic S
Year: 2005
Journal: Mol Cell Biol
Title: Coordinated regulation of insulin signaling by the protein tyrosine phosphatases PTP1B and TCPTP.
Volume: 25
Issue: 2
Pages: 819-29
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16198645 | J:104889
First Author: Dubé N
Year: 2005
Journal: Biochim Biophys Acta
Title: Involvement of the small protein tyrosine phosphatases TC-PTP and PTP1B in signal transduction and diseases: from diabetes, obesity to cell cycle, and cancer.
Volume: 1754
Issue: 1-2
Pages: 108-17
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20059965 | J:157870
First Author: Blanquart C
Year: 2010
Journal: Biochem Biophys Res Commun
Title: Protein tyrosine phosphatase-1B and T-cell protein tyrosine phosphatase regulate IGF-2-induced MCF-7 cell migration.
Volume: 392
Issue: 1
Pages: 83-8
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16705167 | J:109622
First Author: Simoncic PD
Year: 2006
Journal: Mol Cell Biol
Title: T-cell protein tyrosine phosphatase (Tcptp) is a negative regulator of colony-stimulating factor 1 signaling and macrophage differentiation.
Volume: 26
Issue: 11
Pages: 4149-60
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12138178 | J:197518
First Author: ten Hoeve J
Year: 2002
Journal: Mol Cell Biol
Title: Identification of a nuclear Stat1 protein tyrosine phosphatase.
Volume: 22
Issue: 16
Pages: 5662-8
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17210636 | J:197516
First Author: Lu X
Year: 2007
Journal: Mol Cell Biol
Title: T-cell protein tyrosine phosphatase, distinctively expressed in activated-B-cell-like diffuse large B-cell lymphomas, is the nuclear phosphatase of STAT6.
Volume: 27
Issue: 6
Pages: 2166-79
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12612081 | J:196641
First Author: Galic S
Year: 2003
Journal: Mol Cell Biol
Title: Regulation of insulin receptor signaling by the protein tyrosine phosphatase TCPTP.
Volume: 23
Issue: 6
Pages: 2096-108
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21435452 | J:169850
First Author: Nesterovitch AB
Year: 2011
Journal: Am J Pathol
Title: Spontaneous insertion of a b2 element in the ptpn6 gene drives a systemic autoinflammatory disease in mice resembling neutrophilic dermatosis in humans.
Volume: 178
Issue: 4
Pages: 1701-14
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19755676 | J:155497
First Author: Young RM
Year: 2009
Journal: Blood
Title: TC-PTP is required for the maintenance of MYC-driven B-cell lymphomas.
Volume: 114
Issue: 24
Pages: 5016-23
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30230471 | J:268052
   
First Author: Dodd GT
Year: 2018
Journal: Elife
Title: Insulin regulates POMC neuronal plasticity to control glucose metabolism.
Volume: 7
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23166300 | J:194223
First Author: Shields BJ
Year: 2013
Journal: Mol Cell Biol
Title: TCPTP regulates SFK and STAT3 signaling and is lost in triple-negative breast cancers.
Volume: 33
Issue: 3
Pages: 557-70
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31361966 | J:298807
First Author: Xu C
Year: 2019
Journal: FASEB J
Title: Protein tyrosine phosphatase 11 acts through RhoA/ROCK to regulate eosinophil accumulation in the allergic airway.
Volume: 33
Issue: 11
Pages: 11706-11720
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15592458 | J:196638
First Author: Mattila E
Year: 2005
Journal: Nat Cell Biol
Title: Negative regulation of EGFR signalling through integrin-alpha1beta1-mediated activation of protein tyrosine phosphatase TCPTP.
Volume: 7
Issue: 1
Pages: 78-85
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25594176 | J:219581
First Author: Dodd GT
Year: 2015
Journal: Cell
Title: Leptin and insulin act on POMC neurons to promote the browning of white fat.
Volume: 160
Issue: 1-2
Pages: 88-104
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22000926 | J:179621
First Author: Loh K
Year: 2011
Journal: Cell Metab
Title: Elevated hypothalamic TCPTP in obesity contributes to cellular leptin resistance.
Volume: 14
Issue: 5
Pages: 684-99
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28768176 | J:253171
First Author: Dodd GT
Year: 2017
Journal: Cell Metab
Title: A Hypothalamic Phosphatase Switch Coordinates Energy Expenditure with Feeding.
Volume: 26
Issue: 2
Pages: 375-393.e7
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29712668 | J:264814
First Author: Dodd GT
Year: 2018
Journal: Diabetes
Title: TCPTP Regulates Insulin Signaling in AgRP Neurons to Coordinate Glucose Metabolism With Feeding.
Volume: 67
Issue: 7
Pages: 1246-1257
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19930043 | J:162283
First Author: Pouliot P
Year: 2009
Journal: Immunology
Title: The role of protein tyrosine phosphatases in the regulation of allergic asthma: implication of TC-PTP and PTP-1B in the modulation of disease development.
Volume: 128
Issue: 4
Pages: 534-42
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16971512 | J:117940
First Author: Karlsson S
Year: 2006
Journal: Mol Biol Cell
Title: Loss of T-cell protein tyrosine phosphatase induces recycling of the platelet-derived growth factor (PDGF) beta-receptor but not the PDGF alpha-receptor.
Volume: 17
Issue: 11
Pages: 4846-55
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18775329 | J:138771
First Author: Mo W
Year: 2008
Journal: Mol Cell
Title: Nuclear beta-arrestin1 functions as a scaffold for the dephosphorylation of STAT1 and moderates the antiviral activity of IFN-gamma.
Volume: 31
Issue: 5
Pages: 695-707
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14966296 | J:88185
First Author: Persson C
Year: 2004
Journal: Mol Cell Biol
Title: Site-selective regulation of platelet-derived growth factor beta receptor tyrosine phosphorylation by T-cell protein tyrosine phosphatase.
Volume: 24
Issue: 5
Pages: 2190-201
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30454647 | J:267427
First Author: Grohmann M
Year: 2018
Journal: Cell
Title: Obesity Drives STAT-1-Dependent NASH and STAT-3-Dependent HCC.
Volume: 175
Issue: 5
Pages: 1289-1306.e20
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26026268 | J:223391
First Author: Ren F
Year: 2015
Journal: FEBS Lett
Title: Nuclear termination of STAT3 signaling through SIPAR (STAT3-Interacting Protein As a Repressor)-dependent recruitment of T cell tyrosine phosphatase TC-PTP.
Volume: 589
Issue: 15
Pages: 1890-6
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8267598 | J:16055
First Author: Kaneko Y
Year: 1993
Journal: Biochem Biophys Res Commun
Title: Identification of protein tyrosine phosphatases expressed in murine male germ cells.
Volume: 197
Issue: 2
Pages: 625-31
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27841348 | J:242865
 
First Author: Cho JH
Year: 2016
Journal: Nat Commun
Title: CD45-mediated control of TCR tuning in naïve and memory CD8+ T cells.
Volume: 7
Pages: 13373
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33637536 | J:335838
 
First Author: Dodd GT
Year: 2021
Journal: Sci Adv
Title: Insulin signaling in AgRP neurons regulates meal size to limit glucose excursions and insulin resistance.
Volume: 7
Issue: 9
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20421975 | J:160140
First Author: Kim DJ
Year: 2010
Journal: PLoS One
Title: Protein tyrosine phosphatases, TC-PTP, SHP1, and SHP2, cooperate in rapid dephosphorylation of Stat3 in keratinocytes following UVB irradiation.
Volume: 5
Issue: 4
Pages: e10290
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20924113 | J:165561
First Author: Papadakis AI
Year: 2010
Journal: Cancer Res
Title: eIF2{alpha} Kinase PKR modulates the hypoxic response by Stat3-dependent transcriptional suppression of HIF-1{alpha}.
Volume: 70
Issue: 20
Pages: 7820-9
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36370710 | J:333386
First Author: Wang X
Year: 2023
Journal: Neuron
Title: Driving axon regeneration by orchestrating neuronal and non-neuronal innate immune responses via the IFNγ-cGAS-STING axis.
Volume: 111
Issue: 2
Pages: 236-255.e7
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8875997 | J:36011
First Author: Huang K
Year: 1996
Journal: Oncogene
Title: Cloning and characterization of PTP-K1, a novel nonreceptor protein tyrosine phosphatase highly expressed in bone marrow.
Volume: 13
Issue: 7
Pages: 1567-73
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27626668 | J:238993
First Author: Kaneko K
Year: 2016
Journal: Cell Rep
Title: Neuronal Rap1 Regulates Energy Balance, Glucose Homeostasis, and Leptin Actions.
Volume: 16
Issue: 11
Pages: 3003-3015
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19727691 | J:157883
First Author: Reinhard J
Year: 2009
Journal: Exp Brain Res
Title: Protein tyrosine phosphatases expression during development of mouse superior colliculus.
Volume: 199
Issue: 3-4
Pages: 279-97
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- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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- | J:175295
     
First Author: Mouse Genome Informatics and the Wellcome Trust Sanger Institute Mouse Genetics Project (MGP)
Year: 2011
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the Wellcome Trust Sanger Institute (WTSI) Mouse Resources Portal
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30973865 | J:274872
First Author: Ingham NJ
Year: 2019
Journal: PLoS Biol
Title: Mouse screen reveals multiple new genes underlying mouse and human hearing loss.
Volume: 17
Issue: 4
Pages: e3000194
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12904583 | J:85162
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
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17967808 | J:152068
First Author: Friedel RH
Year: 2007
Journal: Brief Funct Genomic Proteomic
Title: EUCOMM--the European conditional mouse mutagenesis program.
Volume: 6
Issue: 3
Pages: 180-5
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- | J:80155
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations for FANTOM2 data
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12520002 | J:91812
First Author: Stryke D
Year: 2003
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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