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Search results 101 to 186 out of 186 for Card9

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Type Details Score
Publication
30781796 | J:340378
 
First Author: Heß R
Year: 2019
Journal: Viruses
Title: Glycosylation of HIV Env Impacts IgG Subtype Responses to Vaccination.
Volume: 11
Issue: 2
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19703985 | J:152148
First Author: Robinson MJ
Year: 2009
Journal: J Exp Med
Title: Dectin-2 is a Syk-coupled pattern recognition receptor crucial for Th17 responses to fungal infection.
Volume: 206
Issue: 9
Pages: 2037-51
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32991669 | J:307311
 
First Author: Nagata M
Year: 2021
Journal: J Exp Med
Title: Helicobacter pylori metabolites exacerbate gastritis through C-type lectin receptors.
Volume: 218
Issue: 1
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25530156 | J:223242
First Author: Phongsisay V
Year: 2015
Journal: Mol Immunol
Title: Toll-like receptors recognize distinct proteinase-resistant glycoconjugates in Campylobacter jejuni and Escherichia coli.
Volume: 64
Issue: 1
Pages: 195-203
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35316647 | J:337392
First Author: Li DD
Year: 2022
Journal: Cell Host Microbe
Title: Fungal sensing enhances neutrophil metabolic fitness by regulating antifungal Glut1 activity.
Volume: 30
Issue: 4
Pages: 530-544.e6
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24614655 | J:210238
First Author: Hung CY
Year: 2014
Journal: Infect Immun
Title: Interleukin-1 receptor but not Toll-like receptor 2 is essential for MyD88-dependent Th17 immunity to Coccidioides infection.
Volume: 82
Issue: 5
Pages: 2106-14
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20164423 | J:160111
First Author: Schoenen H
Year: 2010
Journal: J Immunol
Title: Cutting edge: Mincle is essential for recognition and adjuvanticity of the mycobacterial cord factor and its synthetic analog trehalose-dibehenate.
Volume: 184
Issue: 6
Pages: 2756-60
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Publication
18776906 | J:141143
First Author: Yamasaki S
Year: 2008
Journal: Nat Immunol
Title: Mincle is an ITAM-coupled activating receptor that senses damaged cells.
Volume: 9
Issue: 10
Pages: 1179-88
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Publication
20493731 | J:160680
First Author: Saijo S
Year: 2010
Journal: Immunity
Title: Dectin-2 recognition of alpha-mannans and induction of Th17 cell differentiation is essential for host defense against Candida albicans.
Volume: 32
Issue: 5
Pages: 681-91
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Publication
21205640 | J:172265
First Author: Atarashi K
Year: 2011
Journal: Science
Title: Induction of colonic regulatory T cells by indigenous Clostridium species.
Volume: 331
Issue: 6015
Pages: 337-41
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Publication
38170734 | J:344288
First Author: Muraosa Y
Year: 2024
Journal: PLoS Pathog
Title: Fungal chitin-binding glycoprotein induces Dectin-2-mediated allergic airway inflammation synergistically with chitin.
Volume: 20
Issue: 1
Pages: e1011878
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Publication
25004110 | J:347757
First Author: Phongsisay V
Year: 2014
Journal: Mol Immunol
Title: LMIR5 extracellular domain activates myeloid cells through toll-like receptor 4.
Volume: 62
Issue: 1
Pages: 169-77
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Publication
24185614 | J:209011
First Author: Hara H
Year: 2013
Journal: Nat Immunol
Title: Phosphorylation of the adaptor ASC acts as a molecular switch that controls the formation of speck-like aggregates and inflammasome activity.
Volume: 14
Issue: 12
Pages: 1247-55
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Publication
32485165 | J:305370
First Author: Guo Y
Year: 2020
Journal: Cell Host Microbe
Title: During Aspergillus Infection, Monocyte-Derived DCs, Neutrophils, and Plasmacytoid DCs Enhance Innate Immune Defense through CXCR3-Dependent Crosstalk.
Volume: 28
Issue: 1
Pages: 104-116.e4
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Publication
22041900 | J:178744
First Author: Gorjestani S
Year: 2011
Journal: J Biol Chem
Title: Phospholipase Cγ2 (PLCγ2) is key component in Dectin-2 signaling pathway, mediating anti-fungal innate immune responses.
Volume: 286
Issue: 51
Pages: 43651-9
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Publication
25675510 | J:220172
First Author: Baldwin KT
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Neuroinflammation triggered by β-glucan/dectin-1 signaling enables CNS axon regeneration.
Volume: 112
Issue: 8
Pages: 2581-6
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Publication
26140582 | J:233060
First Author: Wüthrich M
Year: 2015
Journal: Eur J Immunol
Title: Fonsecaea pedrosoi-induced Th17-cell differentiation in mice is fostered by Dectin-2 and suppressed by Mincle recognition.
Volume: 45
Issue: 9
Pages: 2542-52
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22905357 | J:187712
First Author: Ippagunta SK
Year: 2012
Journal: Nat Immunol
Title: Addendum: defective Dock2 expression in a subset of ASC-deficient mouse lines.
Volume: 13
Issue: 7
Pages: 701-2
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28130494 | J:247745
First Author: Rhoads JP
Year: 2017
Journal: J Immunol
Title: Oxidized Low-Density Lipoprotein Immune Complex Priming of the Nlrp3 Inflammasome Involves TLR and FcγR Cooperation and Is Dependent on CARD9.
Volume: 198
Issue: 5
Pages: 2105-2114
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29101209 | J:260574
 
First Author: Verma AH
Year: 2017
Journal: Sci Immunol
Title: Oral epithelial cells orchestrate innate type 17 responses to Candida albicans through the virulence factor candidalysin.
Volume: 2
Issue: 17
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Publication
35584674 | J:324991
First Author: Shao TY
Year: 2022
Journal: Cell Rep
Title: Candida albicans oscillating UME6 expression during intestinal colonization primes systemic Th17 protective immunity.
Volume: 39
Issue: 7
Pages: 110837
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36185364 | J:330543
First Author: Zeng Q
Year: 2022
Journal: iScience
Title: Cbl-b restrains priming of pathogenic Th17 cells via the inhibition of IL-6 production by macrophages.
Volume: 25
Issue: 10
Pages: 105151
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23770228 | J:207582
First Author: del Fresno C
Year: 2013
Journal: Immunity
Title: Interferon-β production via Dectin-1-Syk-IRF5 signaling in dendritic cells is crucial for immunity to C. albicans.
Volume: 38
Issue: 6
Pages: 1176-86
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32601220 | J:291532
First Author: Hurabielle C
Year: 2020
Journal: Proc Natl Acad Sci U S A
Title: Immunity to commensal skin fungi promotes psoriasiform skin inflammation.
Volume: 117
Issue: 28
Pages: 16465-16474
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31719149 | J:286548
First Author: Dasari TK
Year: 2020
Journal: J Biol Chem
Title: The nonreceptor tyrosine kinase SYK drives caspase-8/NLRP3 inflammasome-mediated autoinflammatory osteomyelitis.
Volume: 295
Issue: 11
Pages: 3394-3400
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22101787 | J:179821
First Author: Dorhoi A
Year: 2012
Journal: Eur J Immunol
Title: Activation of the NLRP3 inflammasome by Mycobacterium tuberculosis is uncoupled from susceptibility to active tuberculosis.
Volume: 42
Issue: 2
Pages: 374-84
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19139169 | J:144021
First Author: Werninghaus K
Year: 2009
Journal: J Exp Med
Title: Adjuvanticity of a synthetic cord factor analogue for subunit Mycobacterium tuberculosis vaccination requires FcRgamma-Syk-Card9-dependent innate immune activation.
Volume: 206
Issue: 1
Pages: 89-97
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31825833 | J:297790
First Author: Suhail A
Year: 2019
Journal: Cell Rep
Title: DeSUMOylase SENP7-Mediated Epithelial Signaling Triggers Intestinal Inflammation via Expansion of Gamma-Delta T Cells.
Volume: 29
Issue: 11
Pages: 3522-3538.e7
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Publication
35148840 | J:337169
First Author: Borriello F
Year: 2022
Journal: Cell
Title: An adjuvant strategy enabled by modulation of the physical properties of microbial ligands expands antigen immunogenicity.
Volume: 185
Issue: 4
Pages: 614-629.e21
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Publication
24722226 | J:247229
First Author: Wagener J
Year: 2014
Journal: PLoS Pathog
Title: Fungal chitin dampens inflammation through IL-10 induction mediated by NOD2 and TLR9 activation.
Volume: 10
Issue: 4
Pages: e1004050
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Publication
31169521 | J:295265
First Author: Miyabe C
Year: 2019
Journal: J Clin Invest
Title: Dectin-2-induced CCL2 production in tissue-resident macrophages ignites cardiac arteritis.
Volume: 129
Issue: 9
Pages: 3610-3624
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Publication
29576482 | J:272677
First Author: Hernández-Santos N
Year: 2018
Journal: Cell Host Microbe
Title: Lung Epithelial Cells Coordinate Innate Lymphocytes and Immunity against Pulmonary Fungal Infection.
Volume: 23
Issue: 4
Pages: 511-522.e5
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Publication
30510167 | J:287363
First Author: Briard B
Year: 2019
Journal: Nat Microbiol
Title: Fungal ligands released by innate immune effectors promote inflammasome activation during Aspergillus fumigatus infection.
Volume: 4
Issue: 2
Pages: 316-327
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Publication
28400473 | J:242009
First Author: Choo MK
Year: 2017
Journal: J Exp Med
Title: TLR sensing of bacterial spore-associated RNA triggers host immune responses with detrimental effects.
Volume: 214
Issue: 5
Pages: 1297-1311
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Publication
- | J:104881
     
First Author: The RIKEN BioResource Center
Year: 2006
Journal: Unpublished
Title: Information obtained from The RIKEN BioResource Center
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30973865 | J:274872
First Author: Ingham NJ
Year: 2019
Journal: PLoS Biol
Title: Mouse screen reveals multiple new genes underlying mouse and human hearing loss.
Volume: 17
Issue: 4
Pages: e3000194
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Publication
- | J:84900
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Journal: Database Download
Title: Integrating Computational Gene Models into the Mouse Genome Informatics (MGI) Database
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:72247
       
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
35432375 | J:323626
 
First Author: Liu X
Year: 2022
Journal: Front Immunol
Title: CARD9 Signaling, Inflammation, and Diseases.
Volume: 13
Pages: 880879
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Publication
30872079 | J:274182
 
First Author: Zhong X
Year: 2019
Journal: Cancer Lett
Title: Card9 as a critical regulator of tumor development.
Volume: 451
Pages: 150-155
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HT Experiment
GSE232636 | CARD9 attenuates Ab pathology and modifies microglial responses in an Alzheimer's disease mouse model
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Publication
19076343 | -
 
First Author: Ruland J
Year: 2008
Journal: Ann N Y Acad Sci
Title: CARD9 signaling in the innate immune response.
Volume: 1143
Pages: 35-44
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Publication
19359218 | -
First Author: Hara H
Year: 2009
Journal: Trends Immunol
Title: CARD9 versus CARMA1 in innate and adaptive immunity.
Volume: 30
Issue: 5
Pages: 234-42
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Interaction Experiment
Xu Z (2022)
Description: Card9 protects fungal peritonitis through regulating Malt1-mediated activation of autophagy in macrophage.
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Publication
32548948 | -
First Author: Kottom TJ
Year: 2020
Journal: Cell Microbiol
Title: A critical role for CARD9 in pneumocystis pneumonia host defence.
Volume: 22
Issue: 10
Pages: e13235
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Publication
37276426 | -
First Author: Ennerfelt H
Year: 2023
Journal: Proc Natl Acad Sci U S A
Title: CARD9 attenuates Aβ pathology and modifies microglial responses in an Alzheimer's disease mouse model.
Volume: 120
Issue: 24
Pages: e2303760120
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Publication
17468049 | -
First Author: Thome M
Year: 2007
Journal: Trends Immunol
Title: Post-translational modifications regulate distinct functions of CARMA1 and BCL10.
Volume: 28
Issue: 6
Pages: 281-8
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Publication
30022982 | -
 
First Author: Gehring T
Year: 2018
Journal: Front Immunol
Title: BCL10 - Bridging CARDs to Immune Activation.
Volume: 9
Pages: 1539
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Protein Domain
IPR042143 | CARD_BCL10
Type: Domain
Description: This entry represents the CARD domain found in B-cell lymphoma/leukemia 10 (BCL10). BCL10 and Malt1 (mucosa-associated lymphoid tissue-lymphoma-translocation gene 1) are the integral components of CBM signalosomes. They associate with CARD9 to form M-CBM (CBM complex in myeloid immune cells) and with CARMA1 to form L-CBM (CBM complex in lymphoid immune cells), to mediate activation of NF-kB and MAPK by ITAM-coupled receptors expressed on immune cells. Both CARMA1 and CARD9 associate with BCL10 via a CARD-CARD interaction [, ].In general, CARDs are death domains (DDs) found associated with caspases []. They are known to be important in the signaling pathways for apoptosis, inflammation, and host-defense mechanisms []. DDs are protein-protein interaction domains found in a variety of domain architectures. Their common feature is that they form homodimers by self-association or heterodimers by associating with other members of the DD superfamily including PYRIN and DED (Death Effector Domain). They serve as adaptors in signaling pathways and can recruit other proteins into signaling complexes [].
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Protein Domain
IPR042142 | CARD_CARD9
Type: Domain
Description: This entry represents the CARD domain found in CARD9, which is a central regulator of innate immunity and is highly expressed in dendritic cells and macrophages []. Together with BCL10 (B-cell lymphoma 10) and Malt1 (mucosa-associated lymphoid tissue-lymphoma-translocation gene 1), it forms the M-CBM signalosome (the CBM complex in myeloid immune cells), which mediates activation of NF-kB and MAPK by ITAM-coupled receptors expressed on immune cells. CARD9 associates with BCL10 via a CARD-CARD interaction [].In general, CARDs are death domains (DDs) found associated with caspases []. They are known to be important in the signaling pathways for apoptosis, inflammation, and host-defense mechanisms []. DDs are protein-protein interaction domains found in a variety of domain architectures. Their common feature is that they form homodimers by self-association or heterodimers by associating with other members of the DD superfamily including PYRIN and DED (Death Effector Domain). They serve as adaptors in signaling pathways and can recruit other proteins into signaling complexes [].
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Publication
33789983 | J:307961
First Author: Chen X
Year: 2021
Journal: J Immunol
Title: OTUD1 Regulates Antifungal Innate Immunity through Deubiquitination of CARD9.
Volume: 206
Issue: 8
Pages: 1832-1843
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Publication
27542117 | J:246767
First Author: Wang H
Year: 2016
Journal: PLoS Pathog
Title: MyD88 Shapes Vaccine Immunity by Extrinsically Regulating Survival of CD4+ T Cells during the Contraction Phase.
Volume: 12
Issue: 8
Pages: e1005787
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Publication
32941658 | J:304610
First Author: Wolf AJ
Year: 2021
Journal: J Leukoc Biol
Title: Malassezia spp. induce inflammatory cytokines and activate NLRP3 inflammasomes in phagocytes.
Volume: 109
Issue: 1
Pages: 161-172
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Publication
19136564 | J:148372
First Author: Xu S
Year: 2009
Journal: J Biol Chem
Title: Phospholipase Cgamma2 is critical for Dectin-1-mediated Ca2+ flux and cytokine production in dendritic cells.
Volume: 284
Issue: 11
Pages: 7038-46
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Publication
22921586 | J:312801
First Author: Schweneker K
Year: 2013
Journal: Immunobiology
Title: The mycobacterial cord factor adjuvant analogue trehalose-6,6'-dibehenate (TDB) activates the Nlrp3 inflammasome.
Volume: 218
Issue: 4
Pages: 664-73
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Protein
Q9Z0H7
Organism: Mus musculus/domesticus
Length: 233  
Fragment?: false
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Protein
Q3THY9
Organism: Mus musculus/domesticus
Length: 278  
Fragment?: false
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Protein
B7ZWE5
Organism: Mus musculus/domesticus
Length: 233  
Fragment?: false
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Publication
34480018 | J:312552
First Author: Li D
Year: 2021
Journal: Cell Death Dis
Title: C-type lectin receptor Dectin3 deficiency balances the accumulation and function of FoxO1-mediated LOX-1+ M-MDSCs in relieving lupus-like symptoms.
Volume: 12
Issue: 9
Pages: 829
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Publication
24478101 | J:209805
First Author: Mao L
Year: 2014
Journal: Infect Immun
Title: Pathogenic fungus Microsporum canis activates the NLRP3 inflammasome.
Volume: 82
Issue: 2
Pages: 882-92
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Protein
A2AIV8
Organism: Mus musculus/domesticus
Length: 536  
Fragment?: false
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Publication
9175472 | -
First Author: Hofmann K
Year: 1997
Journal: Trends Biochem Sci
Title: The CARD domain: a new apoptotic signalling motif.
Volume: 22
Issue: 5
Pages: 155-6
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Publication
12101092 | -
First Author: Bouchier-Hayes L
Year: 2002
Journal: EMBO Rep
Title: CARD games in apoptosis and immunity.
Volume: 3
Issue: 7
Pages: 616-21
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Publication
17201679 | -
 
First Author: Park HH
Year: 2007
Journal: Annu Rev Immunol
Title: The death domain superfamily in intracellular signaling of apoptosis and inflammation.
Volume: 25
Pages: 561-86
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