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Search results 101 to 160 out of 160 for Cdc37

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Type Details Score
Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
10822368 | J:93695
First Author: Stepanova L
Year: 2000
Journal: Oncogene
Title: Induction of human Cdc37 in prostate cancer correlates with the ability of targeted Cdc37 expression to promote prostatic hyperplasia.
Volume: 19
Issue: 18
Pages: 2186-93
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UniProt Feature
UniProt Feature
Begin: 1
Description: Hsp90 co-chaperone Cdc37
Type: chain
End: 379
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Publication
25852146 | J:221037
First Author: Li D
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: A cytosolic heat shock protein 90 and cochaperone CDC37 complex is required for RIP3 activation during necroptosis.
Volume: 112
Issue: 16
Pages: 5017-22
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Publication
16098195 | -
First Author: Turnbull EL
Year: 2005
Journal: FEBS J
Title: Cdc37 maintains cellular viability in Schizosaccharomyces pombe independently of interactions with heat-shock protein 90.
Volume: 272
Issue: 16
Pages: 4129-40
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Interaction Experiment
Lyu J (2009)
Description: Cdc37 regulates Ryk signaling by stabilizing the cleaved Ryk intracellular domain.
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Interaction Experiment
Boudeau J (2003)
Description: Heat-shock protein 90 and Cdc37 interact with LKB1 and regulate its stability.
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Publication
19269974 | -
First Author: Lyu J
Year: 2009
Journal: J Biol Chem
Title: Cdc37 regulates Ryk signaling by stabilizing the cleaved Ryk intracellular domain.
Volume: 284
Issue: 19
Pages: 12940-8
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Publication
12489981 | -
First Author: Boudeau J
Year: 2003
Journal: Biochem J
Title: Heat-shock protein 90 and Cdc37 interact with LKB1 and regulate its stability.
Volume: 370
Issue: Pt 3
Pages: 849-57
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Allele
Tg(MMTV-Cdc37)1Stp | MGI:3505709
Name: transgene insertion 1, Lilia Stepanova
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Protein Domain
IPR013874 | Cdc37_Hsp90-bd
Type: Domain
Description: Cdc37 is a molecular chaperone required for the activity of numerous eukaryotic protein kinases. This entry corresponds to the Hsp90 chaperone (heat shock protein 90) binding domain of Cdc37 []. It is found between the N-terminal Cdc37 domain (), which is predominantly involved in kinase binding, and the C-terminal domain of Cdc37 () whose function is unclear.
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Protein Coding Gene
MGI:1914322 | Cdc37l1
Type: protein_coding_gene
Organism: mouse, laboratory
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Strain
MGI:2165443 | STOCK Tg(MMTV-Cdc37)1Stp/J
Attribute String: mutant stock, transgenic
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Genotype
Genotype
Symbol: Tg(MMTV-Cdc37)1Stp/?
Background: involves: C57BL/6 * DBA/2 * FVB/N
Zygosity: ot
Has Mutant Allele: true
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Protein Domain
IPR038189 | Cdc37_Hsp90-bd_sf
Type: Homologous_superfamily
Description: Cdc37 is a molecular chaperone required for the activity of numerous eukaryotic protein kinases. The C-terminal segment of Cdc37 is entirely helical in structure, consisting of a large 6-helix bundle at the N-terminal end, connected to a small 3-helix bundle via a long single helix. The Hsp90 N-terminal nucleotide binding domain binds to the large helical domain of Cdc37 []. This entry corresponds to the Hsp90 chaperone (heat shock protein 90) binding domain of Cdc37 [].
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Protein Domain
IPR013855 | Cdc37_N_dom
Type: Domain
Description: Cdc37 is a molecular chaperone required for the activity of numerous eukaryotic protein kinases. This entry corresponds to the N-terminal kinase binding domain of these proteins []. It is found N-terminal to a Hsp90 chaperone (heat shock protein 90) binding domain (). Expression of a construct consisting of only the N-terminal domain of Saccharomyces pombe Cdc37 has been shown to result in cellular viability. This indicates that interactions with the cochaperone Hsp90 may not be essential for Cdc37 function [].
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Allele
Tg(MMTV-Cdc37)2Stp | MGI:3802909
Name: transgene insertion 2, Lilia Stepanova
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Protein Domain
IPR013873 | Cdc37_C
Type: Domain
Description: Cdc37 is a protein required for the activity of numerous eukaryotic protein kinases. This entry corresponds to the C-terminal domain whose function is unclear. It is found C-terminal to the Hsp90 chaperone (heat shock protein 90) binding domain () and the N-terminal kinase binding domain of Cdc37 () [].
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Publication
10409742 | J:230400
First Author: Stewart S
Year: 1999
Journal: Mol Cell Biol
Title: Kinase suppressor of Ras forms a multiprotein signaling complex and modulates MEK localization.
Volume: 19
Issue: 8
Pages: 5523-34
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Genotype
Genotype
Symbol: Tg(MMTV-Cdc37)2Stp/?
Background: involves: C57BL/6 * DBA/2 * FVB/N
Zygosity: ot
Has Mutant Allele: true
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GO Term
GO:1990565 | HSP90-CDC37 chaperone complex
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Allele
Tg(Pbsn-Cdc37)1Stp | MGI:3505712
Name: transgene insertion 1, Lilia Stepanova
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Strain
MGI:2165288 | STOCK Tg(Pbsn-Cdc37)1Stp/J
Attribute String: mutant stock, transgenic
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Strain
MGI:2174600 | FVB.Cg-Tg(Pbsn-Cdc37)1Stp/J
Attribute String: congenic, mutant strain, transgenic
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Genotype
Genotype
Symbol: Tg(MMTV-CCND1)1Esmp/? Tg(MMTV-Cdc37)1Stp/?
Background: involves: C57BL/6 * DBA/2 * FVB/N
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Pbsn-Cdc37)1Stp/?
Background: involves: C57BL/6 * DBA/2 * ICR
Zygosity: ot
Has Mutant Allele: true
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Publication
14718169 | -
First Author: Roe SM
Year: 2004
Journal: Cell
Title: The Mechanism of Hsp90 regulation by the protein kinase-specific cochaperone p50(cdc37).
Volume: 116
Issue: 1
Pages: 87-98
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Genotype
Genotype
Symbol: Tg(MMTV-Cdc37)1Stp/? Tg(MMTV-Myc)141-3Led/?
Background: involves: C57BL/6 * CD-1 * DBA/2 * FVB/N
Zygosity: cx
Has Mutant Allele: true
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Publication
36045118 | J:328262
First Author: Ding L
Year: 2022
Journal: Nat Commun
Title: OXTRHigh stroma fibroblasts control the invasion pattern of oral squamous cell carcinoma via ERK5 signaling.
Volume: 13
Issue: 1
Pages: 5124
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Publication
23263557 | J:192611
First Author: Lee MN
Year: 2013
Journal: Nat Immunol
Title: Identification of regulators of the innate immune response to cytosolic DNA and retroviral infection by an integrative approach.
Volume: 14
Issue: 2
Pages: 179-85
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Publication
17643429 | J:130141
First Author: Theodoraki MA
Year: 2007
Journal: Exp Cell Res
Title: Akt shows variable sensitivity to an Hsp90 inhibitor depending on cell context.
Volume: 313
Issue: 18
Pages: 3851-8
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Publication
20671747 | J:186337
First Author: Farhana L
Year: 2011
Journal: Cell Death Differ
Title: Maximal adamantyl-substituted retinoid-related molecule-induced apoptosis requires NF-κB noncanonical and canonical pathway activation.
Volume: 18
Issue: 1
Pages: 164-73
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Publication
23823123 | J:215965
First Author: Bottermann K
Year: 2013
Journal: PLoS One
Title: Systematic Analysis Reveals Elongation Factor 2 and α-Enolase as Novel Interaction Partners of AKT2.
Volume: 8
Issue: 6
Pages: e66045
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Protein Coding Gene
MGI:96247 | Hsp90ab1
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
34090924 | J:307149
 
First Author: Regua AT
Year: 2021
Journal: Cancer Lett
Title: Transgenic mouse models of breast cancer.
Volume: 516
Pages: 73-83
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Publication
15489334 | -
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
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Publication
21183079 | J:292518
First Author: Huttlin EL
Year: 2010
Journal: Cell
Title: A tissue-specific atlas of mouse protein phosphorylation and expression.
Volume: 143
Issue: 7
Pages: 1174-89
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Publication
19468303 | -
First Author: Church DM
Year: 2009
Journal: PLoS Biol
Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.
Volume: 7
Issue: 5
Pages: e1000112
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