|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 101 to 200 out of 390 for Cgas

0.024s
Type Details Score
Publication
First Author: Yu CH
Year: 2020
Journal: Cell
Title: TDP-43 Triggers Mitochondrial DNA Release via mPTP to Activate cGAS/STING in ALS.
Volume: 183
Issue: 3
Pages: 636-649.e18
Publication
First Author: Li J
Year: 2022
Journal: Int Immunopharmacol
Title: Blocking cGAS/STING signaling protects against sepsis-associated acute liver injury.
Volume: 113
Issue: Pt A
Pages: 109276
Publication  
First Author: Li W
Year: 2020
Journal: Sci Transl Med
Title: cGAS-STING-mediated DNA sensing maintains CD8+ T cell stemness and promotes antitumor T cell therapy.
Volume: 12
Issue: 549
Publication
First Author: Elsner C
Year: 2020
Journal: Proc Natl Acad Sci U S A
Title: Absence of cGAS-mediated type I IFN responses in HIV-1-infected T cells.
Volume: 117
Issue: 32
Pages: 19475-19486
Publication  
First Author: Alonso Paiva IM
Year: 2023
Journal: Front Immunol
Title: Role of the cGAS/STING pathway in the control of Brucella abortus infection acquired through the respiratory route.
Volume: 14
Pages: 1116811
Publication
First Author: Souza C
Year: 2020
Journal: Sci Rep
Title: The role of the adaptor molecule STING during Schistosoma mansoni infection.
Volume: 10
Issue: 1
Pages: 7901
Publication  
First Author: Ruiz-Moreno JS
Year: 2018
Journal: Infect Immun
Title: The cGAS/STING Pathway Detects Streptococcus pneumoniae but Appears Dispensable for Antipneumococcal Defense in Mice and Humans.
Volume: 86
Issue: 3
Publication
First Author: Su X
Year: 2022
Journal: Infect Immun
Title: Evidence for cGAS-STING Signaling in the Female Genital Tract Resistance to Chlamydia trachomatis Infection.
Volume: 90
Issue: 2
Pages: e0067021
Publication
First Author: Liu H
Year: 2023
Journal: PLoS Pathog
Title: Innate sensing of picornavirus infection involves cGAS-STING-mediated antiviral responses triggered by mitochondrial DNA release.
Volume: 19
Issue: 2
Pages: e1011132
Publication  
First Author: Han F
Year: 2021
Journal: Exp Eye Res
Title: The cGAS-STING signaling pathway contributes to the inflammatory response and autophagy in Aspergillus fumigatus keratitis.
Volume: 202
Pages: 108366
Publication  
First Author: Motwani M
Year: 2021
Journal: Front Immunol
Title: cGAS-STING Pathway Does Not Promote Autoimmunity in Murine Models of SLE.
Volume: 12
Pages: 605930
Publication
First Author: Marcus A
Year: 2018
Journal: Immunity
Title: Tumor-Derived cGAMP Triggers a STING-Mediated Interferon Response in Non-tumor Cells to Activate the NK Cell Response.
Volume: 49
Issue: 4
Pages: 754-763.e4
Publication
First Author: Banerjee D
Year: 2021
Journal: Nat Commun
Title: A non-canonical, interferon-independent signaling activity of cGAMP triggers DNA damage response signaling.
Volume: 12
Issue: 1
Pages: 6207
Publication
First Author: En A
Year: 2024
Journal: Cell Rep
Title: Pervasive nuclear envelope ruptures precede ECM signaling and disease onset without activating cGAS-STING in Lamin-cardiomyopathy mice.
Volume: 43
Issue: 6
Pages: 114284
Publication
First Author: Luther J
Year: 2020
Journal: Proc Natl Acad Sci U S A
Title: Hepatic gap junctions amplify alcohol liver injury by propagating cGAS-mediated IRF3 activation.
Volume: 117
Issue: 21
Pages: 11667-11673
Publication
First Author: Gulen MF
Year: 2023
Journal: Nature
Title: cGAS-STING drives ageing-related inflammation and neurodegeneration.
Volume: 620
Issue: 7973
Pages: 374-380
Publication
First Author: Skouboe MK
Year: 2018
Journal: PLoS Pathog
Title: STING agonists enable antiviral cross-talk between human cells and confer protection against genital herpes in mice.
Volume: 14
Issue: 4
Pages: e1006976
Publication
First Author: de Mingo Pulido Á
Year: 2021
Journal: Immunity
Title: The inhibitory receptor TIM-3 limits activation of the cGAS-STING pathway in intra-tumoral dendritic cells by suppressing extracellular DNA uptake.
Volume: 54
Issue: 6
Pages: 1154-1167.e7
Publication
First Author: Benmerzoug S
Year: 2018
Journal: Nat Commun
Title: STING-dependent sensing of self-DNA drives silica-induced lung inflammation.
Volume: 9
Issue: 1
Pages: 5226
Publication
First Author: Leibowitz BJ
Year: 2021
Journal: Sci Adv
Title: Interferon b drives intestinal regeneration after radiation.
Volume: 7
Issue: 41
Pages: eabi5253
Publication
First Author: Rai P
Year: 2021
Journal: Nat Immunol
Title: IRGM1 links mitochondrial quality control to autoimmunity.
Volume: 22
Issue: 3
Pages: 312-321
Publication
First Author: Wang X
Year: 2023
Journal: Neuron
Title: Driving axon regeneration by orchestrating neuronal and non-neuronal innate immune responses via the IFNγ-cGAS-STING axis.
Volume: 111
Issue: 2
Pages: 236-255.e7
Publication  
First Author: Hahn WO
Year: 2018
Journal: JCI Insight
Title: cGAS-mediated control of blood-stage malaria promotes Plasmodium-specific germinal center responses.
Volume: 3
Issue: 2
Publication
First Author: Liang X
Year: 2024
Journal: Nat Commun
Title: TET2 germline variants promote kidney disease by impairing DNA repair and activating cytosolic nucleotide sensors.
Volume: 15
Issue: 1
Pages: 9621
Publication  
First Author: Cheng WY
Year: 2018
Journal: Front Immunol
Title: The cGas-Sting Signaling Pathway Is Required for the Innate Immune Response Against Ectromelia Virus.
Volume: 9
Pages: 1297
Publication
First Author: Farris LC
Year: 2023
Journal: J Immunol
Title: Borrelia burgdorferi Engages Mammalian Type I IFN Responses via the cGAS-STING Pathway.
Volume: 210
Issue: 11
Pages: 1761-1770
Publication
First Author: Liao Y
Year: 2020
Journal: Theranostics
Title: HDAC3 inhibition ameliorates ischemia/reperfusion-induced brain injury by regulating the microglial cGAS-STING pathway.
Volume: 10
Issue: 21
Pages: 9644-9662
Publication
First Author: Gao H
Year: 2022
Journal: J Am Heart Assoc
Title: Microbial DNA Enrichment Promotes Adrenomedullary Inflammation, Catecholamine Secretion, and Hypertension in Obese Mice.
Volume: 11
Issue: 4
Pages: e024561
Publication  
First Author: Fritsch LE
Year: 2022
Journal: Front Mol Neurosci
Title: Type I Interferon Response Is Mediated by NLRX1-cGAS-STING Signaling in Brain Injury.
Volume: 15
Pages: 852243
Publication
First Author: Aditi
Year: 2021
Journal: Neuron
Title: Genome instability independent of type I interferon signaling drives neuropathology caused by impaired ribonucleotide excision repair.
Volume: 109
Issue: 24
Pages: 3962-3979.e6
Publication
First Author: Marinho FV
Year: 2018
Journal: J Innate Immun
Title: The cGAS/STING Pathway Is Important for Dendritic Cell Activation but Is Not Essential to Induce Protective Immunity against Mycobacterium tuberculosis Infection.
Volume: 10
Issue: 3
Pages: 239-252
Publication
First Author: Chu TT
Year: 2021
Journal: Nature
Title: Tonic prime-boost of STING signalling mediates Niemann-Pick disease type C.
Volume: 596
Issue: 7873
Pages: 570-575
Publication
First Author: Geng X
Year: 2022
Journal: Adv Sci (Weinh)
Title: PICH Supports Embryonic Hematopoiesis by Suppressing a cGAS-STING-Mediated Interferon Response.
Volume: 9
Issue: 7
Pages: e2103837
Publication
First Author: Gao D
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Activation of cyclic GMP-AMP synthase by self-DNA causes autoimmune diseases.
Volume: 112
Issue: 42
Pages: E5699-705
Publication
First Author: Costa Franco MM
Year: 2018
Journal: J Immunol
Title: Brucella abortus Triggers a cGAS-Independent STING Pathway To Induce Host Protection That Involves Guanylate-Binding Proteins and Inflammasome Activation.
Volume: 200
Issue: 2
Pages: 607-622
Publication  
First Author: Stavrou S
Year: 2018
Journal: MBio
Title: DDX41 Recognizes RNA/DNA Retroviral Reverse Transcripts and Is Critical for In Vivo Control of Murine Leukemia Virus Infection.
Volume: 9
Issue: 3
Publication
First Author: Anghelina D
Year: 2016
Journal: J Virol
Title: Diminished Innate Antiviral Response to Adenovirus Vectors in cGAS/STING-Deficient Mice Minimally Impacts Adaptive Immunity.
Volume: 90
Issue: 13
Pages: 5915-27
Publication
First Author: Dai P
Year: 2014
Journal: PLoS Pathog
Title: Modified vaccinia virus Ankara triggers type I IFN production in murine conventional dendritic cells via a cGAS/STING-mediated cytosolic DNA-sensing pathway.
Volume: 10
Issue: 4
Pages: e1003989
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Ablasser A
Year: 2013
Journal: Nature
Title: Cell intrinsic immunity spreads to bystander cells via the intercellular transfer of cGAMP.
Volume: 503
Issue: 7477
Pages: 530-4
Publication  
First Author: Binmama S
Year: 2022
Journal: Int J Mol Sci
Title: Beta-Glucan from S. cerevisiae Protected AOM-Induced Colon Cancer in cGAS-Deficient Mice Partly through Dectin-1-Manipulated Macrophage Cell Energy.
Volume: 23
Issue: 18
Publication
First Author: Wang Y
Year: 2020
Journal: STAR Protoc
Title: Protocol for Monitoring DNA-Triggered cGAS/STING Signaling in Mammalian Cells and Mice.
Volume: 1
Issue: 3
Pages: 100171
Publication  
First Author: Whelan JT
Year: 2022
Journal: Front Immunol
Title: CRISPR-mediated rapid arming of poxvirus vectors enables facile generation of the novel immunotherapeutic STINGPOX.
Volume: 13
Pages: 1050250
Publication
First Author: Harding SM
Year: 2017
Journal: Nature
Title: Mitotic progression following DNA damage enables pattern recognition within micronuclei.
Volume: 548
Issue: 7668
Pages: 466-470
GXD Expression  
Probe: MGI:1438804
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1915528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3585278
Age: postnatal day 6-7
Image: P6/7
Specimen Label: P6/7
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:1438804
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1915528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3585278
Age: postnatal day 8-10
Image: P8/10
Specimen Label: P8/10
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:1438804
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1647028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3585278
Age: postnatal day 6
Note: Expression was widespread.
Specimen Label: CNS
Detected: true
Specimen Num: 4
GXD Expression
Probe: MGI:1438804
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1915728
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:3585278
Age: postnatal day 6-7
Image: P6/7
Note: Expression was detected in the inner segment.
Specimen Label: P6/7
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:1438804
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1915728
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:3585278
Age: postnatal day 8-10
Image: P8/10
Note: Expression was detected in the inner segment.
Specimen Label: P8/10
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:1438804
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Male
Emaps: EMAPS:1915728
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:3585278
Age: postnatal adult
Image: Adult
Note: Expression was detected in the inner segment.
Specimen Label: Adult
Detected: true
Specimen Num: 3
Publication  
First Author: Döring M
Year: 2021
Journal: Sci Signal
Title: Single-cell analysis reveals divergent responses of human dendritic cells to the MVA vaccine.
Volume: 14
Issue: 697
Publication  
First Author: Zhou J
Year: 2021
Journal: Exp Eye Res
Title: cGMP-PKG dependent transcriptome in normal and degenerating retinas: Novel insights into the retinitis pigmentosa pathology.
Volume: 212
Pages: 108752
Publication
First Author: Lv N
Year: 2022
Journal: Aging Cell
Title: Dysfunctional telomeres through mitostress-induced cGAS/STING activation to aggravate immune senescence and viral pneumonia.
Volume: 21
Issue: 4
Pages: e13594
Publication
First Author: Wang F
Year: 2022
Journal: Mol Cell
Title: Cytoplasmic PARP1 links the genome instability to the inhibition of antiviral immunity through PARylating cGAS.
Volume: 82
Issue: 11
Pages: 2032-2049.e7
Publication
First Author: Špiranec Spes K
Year: 2020
Journal: Arterioscler Thromb Vasc Biol
Title: Natriuretic Peptides Attenuate Retinal Pathological Neovascularization Via Cyclic Guanosine Monophosphate Signaling in Pericytes and Astrocytes.
Volume: 40
Issue: 1
Pages: 159-174
Publication
First Author: Tang Q
Year: 2022
Journal: Cell Host Microbe
Title: Thymidine starvation promotes c-di-AMP-dependent inflammation during pathogenic bacterial infection.
Volume: 30
Issue: 7
Pages: 961-974.e6
Publication
First Author: Li XD
Year: 2013
Journal: Science
Title: Pivotal roles of cGAS-cGAMP signaling in antiviral defense and immune adjuvant effects.
Volume: 341
Issue: 6152
Pages: 1390-4
Publication
First Author: Chen J
Year: 2024
Journal: Signal Transduct Target Ther
Title: DNA of neutrophil extracellular traps promote NF-κB-dependent autoimmunity via cGAS/TLR9 in chronic obstructive pulmonary disease.
Volume: 9
Issue: 1
Pages: 163
Publication
First Author: Chauhan M
Year: 2024
Journal: Cell Death Dis
Title: STING dependent BAX-IRF3 signaling results in apoptosis during late-stage Coxiella burnetii infection.
Volume: 15
Issue: 3
Pages: 195
Publication
First Author: Lai J
Year: 2021
Journal: Mol Ther
Title: Zebularine elevates STING expression and enhances cGAMP cancer immunotherapy in mice.
Volume: 29
Issue: 5
Pages: 1758-1771
Publication  
First Author: Joseph JV
Year: 2023
Journal: Cancer Lett
Title: STING activation counters glioblastoma by vascular alteration and immune surveillance.
Volume: 579
Pages: 216480
Publication
First Author: Thomsen MK
Year: 2020
Journal: Oncogene
Title: The cGAS-STING pathway is a therapeutic target in a preclinical model of hepatocellular carcinoma.
Volume: 39
Issue: 8
Pages: 1652-1664
Publication
First Author: Luo S
Year: 2023
Journal: Int Immunopharmacol
Title: Activation of cGAS-STING signaling pathway promotes liver fibrosis and hepatic sinusoidal microthrombosis.
Volume: 125
Issue: Pt B
Pages: 111132
Publication
First Author: Du H
Year: 2023
Journal: iScience
Title: Suppression of TREX1 deficiency-induced cellular senescence and interferonopathies by inhibition of DNA damage response.
Volume: 26
Issue: 7
Pages: 107090
Publication
First Author: Maekawa H
Year: 2019
Journal: Cell Rep
Title: Mitochondrial Damage Causes Inflammation via cGAS-STING Signaling in Acute Kidney Injury.
Volume: 29
Issue: 5
Pages: 1261-1273.e6
Publication
First Author: Adiliaghdam F
Year: 2022
Journal: Sci Immunol
Title: Human enteric viruses autonomously shape inflammatory bowel disease phenotype through divergent innate immunomodulation.
Volume: 7
Issue: 70
Pages: eabn6660
Publication
First Author: Vila IK
Year: 2022
Journal: Cell Metab
Title: STING orchestrates the crosstalk between polyunsaturated fatty acid metabolism and inflammatory responses.
Volume: 34
Issue: 1
Pages: 125-139.e8
Publication
First Author: Cheedipudi SM
Year: 2022
Journal: JACC Basic Transl Sci
Title: Genetic Ablation of the DNA Damage Response Pathway Attenuates Lamin-Associated Dilated Cardiomyopathy in Mice.
Volume: 7
Issue: 12
Pages: 1232-1245
Publication
First Author: Rui WJ
Year: 2022
Journal: Glia
Title: Microglial AIM2 alleviates antiviral-related neuro-inflammation in mouse models of Parkinson's disease.
Volume: 70
Issue: 12
Pages: 2409-2425
Publication
First Author: Moriyama M
Year: 2019
Journal: Nat Commun
Title: Influenza A virus M2 protein triggers mitochondrial DNA-mediated antiviral immune responses.
Volume: 10
Issue: 1
Pages: 4624
Publication  
First Author: Shamseddine A
Year: 2023
Journal: J Exp Med
Title: Innate immune signaling drives late cardiac toxicity following DNA-damaging cancer therapies.
Volume: 220
Issue: 3
Publication  
First Author: Geng T
Year: 2024
Journal: EBioMedicine
Title: UBXN3B is crucial for B lymphopoiesis.
Volume: 106
Pages: 105248
Publication
First Author: Bai J
Year: 2020
Journal: Commun Biol
Title: Mitochondrial stress-activated cGAS-STING pathway inhibits thermogenic program and contributes to overnutrition-induced obesity in mice.
Volume: 3
Issue: 1
Pages: 257
Publication
First Author: Jin M
Year: 2021
Journal: Nat Commun
Title: Tau activates microglia via the PQBP1-cGAS-STING pathway to promote brain inflammation.
Volume: 12
Issue: 1
Pages: 6565
Publication  
First Author: Ulrich-Lewis JT
Year: 2022
Journal: Front Immunol
Title: STING Is Required in Conventional Dendritic Cells for DNA Vaccine Induction of Type I T Helper Cell- Dependent Antibody Responses.
Volume: 13
Pages: 861710
Publication
First Author: Wu J
Year: 2022
Journal: Cell Death Dis
Title: The interaction between STING and NCOA4 exacerbates lethal sepsis by orchestrating ferroptosis and inflammatory responses in macrophages.
Volume: 13
Issue: 7
Pages: 653
Publication
First Author: Bai J
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: DsbA-L prevents obesity-induced inflammation and insulin resistance by suppressing the mtDNA release-activated cGAS-cGAMP-STING pathway.
Volume: 114
Issue: 46
Pages: 12196-12201
Publication
First Author: Mackenzie KJ
Year: 2016
Journal: EMBO J
Title: Ribonuclease H2 mutations induce a cGAS/STING-dependent innate immune response.
Volume: 35
Issue: 8
Pages: 831-44
Publication
First Author: Marques-da-Silva C
Year: 2022
Journal: Cell Rep
Title: Direct type I interferon signaling in hepatocytes controls malaria.
Volume: 40
Issue: 3
Pages: 111098
Publication
First Author: Lima-Junior DS
Year: 2021
Journal: Cell
Title: Endogenous retroviruses promote homeostatic and inflammatory responses to the microbiota.
Volume: 184
Issue: 14
Pages: 3794-3811.e19
Publication
First Author: Perumal N
Year: 2023
Journal: J Immunol
Title: cGAS-STING Pathway Activation during Trypanosoma cruzi Infection Leads to Tissue-Dependent Parasite Control.
Volume: 211
Issue: 7
Pages: 1123-1133
Publication
First Author: Benmerzoug S
Year: 2019
Journal: Cell Rep
Title: Sterile Lung Inflammation Induced by Silica Exacerbates Mycobacterium tuberculosis Infection via STING-Dependent Type 2 Immunity.
Volume: 27
Issue: 9
Pages: 2649-2664.e5