Type |
Details |
Score |
Publication |
First Author: |
Ng D |
Year: |
2009 |
Journal: |
PLoS Biol |
Title: |
Neto1 is a novel CUB-domain NMDA receptor-interacting protein required for synaptic plasticity and learning. |
Volume: |
7 |
Issue: |
2 |
Pages: |
e41 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kim S |
Year: |
2006 |
Journal: |
Nat Neurosci |
Title: |
NGL family PSD-95-interacting adhesion molecules regulate excitatory synapse formation. |
Volume: |
9 |
Issue: |
10 |
Pages: |
1294-301 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yang J |
Year: |
2011 |
Journal: |
EMBO J |
Title: |
DGKι regulates presynaptic release during mGluR-dependent LTD. |
Volume: |
30 |
Issue: |
1 |
Pages: |
165-80 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hertzano R |
Year: |
2007 |
Journal: |
Eur J Neurosci |
Title: |
Lhx3, a LIM domain transcription factor, is regulated by Pou4f3 in the auditory but not in the vestibular system. |
Volume: |
25 |
Issue: |
4 |
Pages: |
999-1005 |
|
•
•
•
•
•
|
Publication |
First Author: |
Fernández E |
Year: |
2009 |
Journal: |
Mol Syst Biol |
Title: |
Targeted tandem affinity purification of PSD-95 recovers core postsynaptic complexes and schizophrenia susceptibility proteins. |
Volume: |
5 |
|
Pages: |
269 |
|
•
•
•
•
•
|
Publication |
First Author: |
Schwenk J |
Year: |
2012 |
Journal: |
Neuron |
Title: |
High-resolution proteomics unravel architecture and molecular diversity of native AMPA receptor complexes. |
Volume: |
74 |
Issue: |
4 |
Pages: |
621-33 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lie E |
Year: |
2016 |
Journal: |
Nat Commun |
Title: |
SALM4 suppresses excitatory synapse development by cis-inhibiting trans-synaptic SALM3-LAR adhesion. |
Volume: |
7 |
|
Pages: |
12328 |
|
•
•
•
•
•
|
Publication |
First Author: |
Eom T |
Year: |
2013 |
Journal: |
Elife |
Title: |
NOVA-dependent regulation of cryptic NMD exons controls synaptic protein levels after seizure. |
Volume: |
2 |
|
Pages: |
e00178 |
|
•
•
•
•
•
|
Publication |
First Author: |
Li J |
Year: |
2017 |
Journal: |
Nat Neurosci |
Title: |
Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders. |
Volume: |
20 |
Issue: |
8 |
Pages: |
1150-1161 |
|
•
•
•
•
•
|
Publication |
First Author: |
Roma G |
Year: |
2007 |
Journal: |
Genome Res |
Title: |
A novel view of the transcriptome revealed from gene trapping in mouse embryonic stem cells. |
Volume: |
17 |
Issue: |
7 |
Pages: |
1051-60 |
|
•
•
•
•
•
|
Publication |
First Author: |
Vaillend C |
Year: |
2008 |
Journal: |
Behav Brain Res |
Title: |
Genes, plasticity and mental retardation. |
Volume: |
192 |
Issue: |
1 |
Pages: |
88-105 |
|
•
•
•
•
•
|
Publication |
First Author: |
García-Frigola C |
Year: |
2004 |
Journal: |
Brain Res Mol Brain Res |
Title: |
A collection of cDNAs enriched in upper cortical layers of the embryonic mouse brain. |
Volume: |
122 |
Issue: |
2 |
Pages: |
133-50 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cox BJ |
Year: |
2010 |
Journal: |
Genome Res |
Title: |
Phenotypic annotation of the mouse X chromosome. |
Volume: |
20 |
Issue: |
8 |
Pages: |
1154-64 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cox BJ |
Year: |
2010 |
Journal: |
MGI Direct Data Submission |
Title: |
Phenotypic annotation of the mouse X chromosome |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Okazaki N |
Year: |
2003 |
Journal: |
DNA Res |
Title: |
Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. |
Volume: |
10 |
Issue: |
1 |
Pages: |
35-48 |
|
•
•
•
•
•
|
Publication |
First Author: |
Araki K |
Year: |
1999 |
Journal: |
Cell Mol Biol (Noisy-le-grand) |
Title: |
Exchangeable gene trap using the Cre/mutated lox system. |
Volume: |
45 |
Issue: |
5 |
Pages: |
737-50 |
|
•
•
•
•
•
|
Publication |
First Author: |
Taniwaki T |
Year: |
2005 |
Journal: |
Dev Growth Differ |
Title: |
Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette. |
Volume: |
47 |
Issue: |
3 |
Pages: |
163-72 |
|
•
•
•
•
•
|
Publication |
First Author: |
The Jackson Laboratory |
Year: |
2005 |
Journal: |
Unpublished |
Title: |
Information obtained from The Jackson Laboratory, Bar Harbor, ME |
|
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|
•
•
•
•
•
|
Publication |
First Author: |
Mammalian Functional Genomics Centre |
Year: |
2010 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the NorCOMM project by the Mammalian Functional Genomics Centre (Mfgc), University of Manitoba |
|
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|
|
•
•
•
•
•
|
Publication |
First Author: |
Ingham NJ |
Year: |
2019 |
Journal: |
PLoS Biol |
Title: |
Mouse screen reveals multiple new genes underlying mouse and human hearing loss. |
Volume: |
17 |
Issue: |
4 |
Pages: |
e3000194 |
|
•
•
•
•
•
|
Publication |
First Author: |
Haiming Tang, Dustin Ebert, Matthias Blum, Robert Finn, Paul Thomas |
Year: |
2023 |
|
Title: |
TreeGrafter-generated GO annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2016 |
|
Title: |
Automatic assignment of GO terms using logical inference, based on on inter-ontology links |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
International Mouse Strain Resource |
Year: |
2014 |
Journal: |
Database Download |
Title: |
MGI download of germline transmission data for alleles from IMSR strain data |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Wellcome Trust Sanger Institute |
Year: |
2010 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC) |
Year: |
2014 |
Journal: |
Database Release |
Title: |
Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Hansen GM |
Year: |
2008 |
Journal: |
Genome Res |
Title: |
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. |
Volume: |
18 |
Issue: |
10 |
Pages: |
1670-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2014 |
|
Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Magdaleno S |
Year: |
2006 |
Journal: |
PLoS Biol |
Title: |
BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. |
Volume: |
4 |
Issue: |
4 |
Pages: |
e86 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Carninci P |
Year: |
2005 |
Journal: |
Science |
Title: |
The transcriptional landscape of the mammalian genome. |
Volume: |
309 |
Issue: |
5740 |
Pages: |
1559-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI) |
Year: |
2008 |
Journal: |
Database Download |
Title: |
Mouse Gene Trap Data Load from dbGSS |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Zambrowicz BP |
Year: |
2003 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. |
Volume: |
100 |
Issue: |
24 |
Pages: |
14109-14 |
|
•
•
•
•
•
|
Publication |
First Author: |
Skarnes WC |
Year: |
2011 |
Journal: |
Nature |
Title: |
A conditional knockout resource for the genome-wide study of mouse gene function. |
Volume: |
474 |
Issue: |
7351 |
Pages: |
337-42 |
|
•
•
•
•
•
|
Publication |
First Author: |
Adams DJ |
Year: |
2024 |
Journal: |
Nature |
Title: |
Genetic determinants of micronucleus formation in vivo. |
Volume: |
627 |
Issue: |
8002 |
Pages: |
130-136 |
|
•
•
•
•
•
|
Publication |
First Author: |
MGD Nomenclature Committee |
Year: |
1995 |
|
Title: |
Nomenclature Committee Use |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators |
Year: |
2011 |
|
Title: |
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2010 |
|
Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Diez-Roux G |
Year: |
2011 |
Journal: |
PLoS Biol |
Title: |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. |
Volume: |
9 |
Issue: |
1 |
Pages: |
e1000582 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
MGI Genome Annotation Group and UniGene Staff |
Year: |
2015 |
Journal: |
Database Download |
Title: |
MGI-UniGene Interconnection Effort |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
Year: |
2010 |
|
Title: |
Annotation inferences using phylogenetic trees |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
|
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|
|
•
•
•
•
•
|
Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
|
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|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
|
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|
|
•
•
•
•
•
|
Publication |
First Author: |
Tarpey P |
Year: |
2004 |
Journal: |
Am J Hum Genet |
Title: |
Mutations in the DLG3 gene cause nonsyndromic X-linked mental retardation. |
Volume: |
75 |
Issue: |
2 |
Pages: |
318-24 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zanni G |
Year: |
2010 |
Journal: |
Neurogenetics |
Title: |
A novel mutation in the DLG3 gene encoding the synapse-associated protein 102 (SAP102) causes non-syndromic mental retardation. |
Volume: |
11 |
Issue: |
2 |
Pages: |
251-5 |
|
•
•
•
•
•
|
Interaction Experiment |
Description: |
Dlg3 trafficking and apical tight junction formation is regulated by nedd4 and nedd4-2 e3ubiquitin ligases. |
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•
•
•
•
|
DO Term |
|
•
•
•
•
•
|
Allele |
Name: |
transgene insertion KG118, GENSAT Project at Rockefeller University |
Allele Type: |
Transgenic |
Attribute String: |
Recombinase |
|
•
•
•
•
•
|
Publication |
First Author: |
Qu M |
Year: |
2009 |
Journal: |
Epilepsy Res |
Title: |
DLG3/SAP102 protein expression in malformations of cortical development: a study of human epileptic cortex by tissue microarray. |
Volume: |
84 |
Issue: |
1 |
Pages: |
33-41 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Domain |
Description: |
DLG3 (discs large homologue 3), also called synapse-associated protein 102 (SAP102), is a scaffolding protein that clusters at synapses and plays an important role in synaptic development and plasticity []. It associates with GluN2 subunits of NMDA receptors, particularly GluN2B which is the dominant subunit in cortical neurons during early development []. Mutations in DLG3 are associated with nonsyndromic X-linked mental retardation in humans [, ]. DLG3 is a member of the MAGUK (membrane-associated guanylate kinase) protein family, which is characterized by the presence of a core of three domains: PDZ, SH3, and guanylate kinase (GuK). The GuK domain in MAGUK proteins is enzymatically inactive; instead, the domain mediates protein-protein interactions and associates intramolecularly with the SH3 domain. DLG3 contains three PDZ domains [].This entry represents the SH3 domain of DLG3. |
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•
•
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Strain |
Attribute String: |
congenic, mutant strain, transgenic |
|
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•
•
•
•
|
Strain |
Attribute String: |
mutant stock, transgenic |
|
•
•
•
•
•
|
Publication |
First Author: |
Zheng CY |
Year: |
2011 |
Journal: |
Neuroscientist |
Title: |
MAGUKs, synaptic development, and synaptic plasticity. |
Volume: |
17 |
Issue: |
5 |
Pages: |
493-512 |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Dlg3-cre)KG118Gsat/? |
Background: |
involves: 129S4/SvJaeSor * FVB/N |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Roberts S |
Year: |
2012 |
Journal: |
FEBS J |
Title: |
The PDZ protein discs-large (DLG): the 'Jekyll and Hyde' of the epithelial polarity proteins. |
Volume: |
279 |
Issue: |
19 |
Pages: |
3549-58 |
|
•
•
•
•
•
|
Publication |
First Author: |
Smith SA |
Year: |
1996 |
Journal: |
Genomics |
Title: |
Isolation of a gene (DLG3) encoding a second member of the discs-large family on chromosome 17q12-q21. |
Volume: |
31 |
Issue: |
2 |
Pages: |
145-50 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cembrowski MS |
Year: |
2016 |
Journal: |
Elife |
Title: |
Hipposeq: a comprehensive RNA-seq database of gene expression in hippocampal principal neurons. |
Volume: |
5 |
|
Pages: |
e14997 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
849
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
950
|
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
835
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
512
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
817
|
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Ding SL |
Year: |
2020 |
Journal: |
Cell Rep |
Title: |
Distinct Transcriptomic Cell Types and Neural Circuits of the Subiculum and Prosubiculum along the Dorsal-Ventral Axis. |
Volume: |
31 |
Issue: |
7 |
Pages: |
107648 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gerfen CR |
Year: |
2013 |
Journal: |
Neuron |
Title: |
GENSAT BAC cre-recombinase driver lines to study the functional organization of cerebral cortical and basal ganglia circuits. |
Volume: |
80 |
Issue: |
6 |
Pages: |
1368-83 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang Q |
Year: |
2023 |
Journal: |
Cell Rep |
Title: |
Regional and cell-type-specific afferent and efferent projections of the mouse claustrum. |
Volume: |
42 |
Issue: |
2 |
Pages: |
112118 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang Q |
Year: |
2020 |
Journal: |
Cell |
Title: |
The Allen Mouse Brain Common Coordinate Framework: A 3D Reference Atlas. |
Volume: |
181 |
Issue: |
4 |
Pages: |
936-953.e20 |
|
•
•
•
•
•
|
Publication |
First Author: |
The Gene Expression Nervous System Atlas (GENSAT) Project, The Rockefeller University (New York, NY) |
Year: |
2005 |
Journal: |
Database Download |
Title: |
MGI download of GENSAT transgene data |
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|
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•
•
•
•
•
|