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Search results 101 to 200 out of 1156 for Flt3

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Type Details Score
Publication
First Author: Boyer SW
Year: 2011
Journal: Cell Stem Cell
Title: All hematopoietic cells develop from hematopoietic stem cells through Flk2/Flt3-positive progenitor cells.
Volume: 9
Issue: 1
Pages: 64-73
Publication
First Author: Beaudin AE
Year: 2014
Journal: Exp Hematol
Title: Flk2/Flt3 promotes both myeloid and lymphoid development by expanding non-self-renewing multipotent hematopoietic progenitor cells.
Volume: 42
Issue: 3
Pages: 218-229.e4
Publication
First Author: Galland F
Year: 1992
Journal: Genomics
Title: Chromosomal localization of FLT4, a novel receptor-type tyrosine kinase gene.
Volume: 13
Issue: 2
Pages: 475-8
Publication
First Author: Esnault C
Year: 2019
Journal: Blood
Title: FLT3-ITD impedes retinoic acid, but not arsenic, responses in murine acute promyelocytic leukemias.
Volume: 133
Issue: 13
Pages: 1495-1506
Publication
First Author: Li L
Year: 2011
Journal: Blood
Title: Loss of the wild-type allele contributes to myeloid expansion and disease aggressiveness in FLT3/ITD knockin mice.
Volume: 118
Issue: 18
Pages: 4935-45
Publication
First Author: Fan J
Year: 2010
Journal: Blood
Title: Cells expressing FLT3/ITD mutations exhibit elevated repair errors generated through alternative NHEJ pathways: implications for genomic instability and therapy.
Volume: 116
Issue: 24
Pages: 5298-305
Publication
First Author: Bailey E
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: FLT3/D835Y mutation knock-in mice display less aggressive disease compared with FLT3/internal tandem duplication (ITD) mice.
Volume: 110
Issue: 52
Pages: 21113-8
Publication
First Author: Li L
Year: 2011
Journal: Blood
Title: Defective nonhomologous end joining blocks B-cell development in FLT3/ITD mice.
Volume: 117
Issue: 11
Pages: 3131-9
Publication
First Author: Wallace JA
Year: 2017
Journal: Blood
Title: miR-155 promotes FLT3-ITD-induced myeloproliferative disease through inhibition of the interferon response.
Volume: 129
Issue: 23
Pages: 3074-3086
Publication
First Author: Khandelwal P
Year: 2013
Journal: PLoS One
Title: Ocular mucosal CD11b+ and CD103+ mouse dendritic cells under normal conditions and in allergic immune responses.
Volume: 8
Issue: 5
Pages: e64193
Publication
First Author: Sambandam A
Year: 2005
Journal: Nat Immunol
Title: Notch signaling controls the generation and differentiation of early T lineage progenitors.
Volume: 6
Issue: 7
Pages: 663-70
Publication
First Author: Yang L
Year: 2016
Journal: Cancer Cell
Title: DNMT3A Loss Drives Enhancer Hypomethylation in FLT3-ITD-Associated Leukemias.
Volume: 29
Issue: 6
Pages: 922-934
Publication
First Author: Zhang H
Year: 2019
Journal: Nat Commun
Title: Clinical resistance to crenolanib in acute myeloid leukemia due to diverse molecular mechanisms.
Volume: 10
Issue: 1
Pages: 244
Publication
First Author: Li LX
Year: 2010
Journal: J Immunol
Title: A Flt3- and Ras-dependent pathway primes B cell development by inducing a state of IL-7 responsiveness.
Volume: 184
Issue: 4
Pages: 1728-36
Publication
First Author: Shih AH
Year: 2015
Journal: Cancer Cell
Title: Mutational cooperativity linked to combinatorial epigenetic gain of function in acute myeloid leukemia.
Volume: 27
Issue: 4
Pages: 502-15
Publication  
First Author: Scheffler JM
Year: 2014
Journal: Nat Commun
Title: LAMTOR2 regulates dendritic cell homeostasis through FLT3-dependent mTOR signalling.
Volume: 5
Pages: 5138
Publication
First Author: Guermonprez P
Year: 2013
Journal: Nat Med
Title: Inflammatory Flt3l is essential to mobilize dendritic cells and for T cell responses during Plasmodium infection.
Volume: 19
Issue: 6
Pages: 730-8
Publication
First Author: Mead AJ
Year: 2013
Journal: Cell Rep
Title: FLT3-ITDs instruct a myeloid differentiation and transformation bias in lymphomyeloid multipotent progenitors.
Volume: 3
Issue: 6
Pages: 1766-76
Publication
First Author: Heuser M
Year: 2010
Journal: Exp Hematol
Title: Extrinsic signals determine myeloid-erythroid lineage switch in MN1 leukemia.
Volume: 38
Issue: 3
Pages: 174-9
Publication
First Author: Yu CI
Year: 2024
Journal: iScience
Title: Engraftment of adult hematopoietic stem and progenitor cells in a novel model of humanized mice.
Volume: 27
Issue: 3
Pages: 109238
Publication
First Author: Durai V
Year: 2018
Journal: J Exp Med
Title: Altered compensatory cytokine signaling underlies the discrepancy between Flt3-/- and Flt3l-/- mice.
Volume: 215
Issue: 5
Pages: 1417-1435
Publication    
First Author: Porter SN
Year: 2016
Journal: Elife
Title: Fetal and neonatal hematopoietic progenitors are functionally and transcriptionally resistant to Flt3-ITD mutations.
Volume: 5
Publication  
First Author: Della Verde G
Year: 2022
Journal: Life Sci Alliance
Title: Fms-like tyrosine kinase 3 is a regulator of the cardiac side population in mice.
Volume: 5
Issue: 3
Publication  
First Author: Bosteels C
Year: 2020
Journal: Front Immunol
Title: CCR2- and Flt3-Dependent Inflammatory Conventional Type 2 Dendritic Cells Are Necessary for the Induction of Adaptive Immunity by the Human Vaccine Adjuvant System AS01.
Volume: 11
Pages: 606805
Publication
First Author: Poitras JL
Year: 2016
Journal: Oncotarget
Title: Dnmt3a deletion cooperates with the Flt3/ITD mutation to drive leukemogenesis in a murine model.
Volume: 7
Issue: 43
Pages: 69124-69135
Publication
First Author: Sasca D
Year: 2014
Journal: Blood
Title: SIRT1 prevents genotoxic stress-induced p53 activation in acute myeloid leukemia.
Volume: 124
Issue: 1
Pages: 121-33
Publication
First Author: Guerrero AD
Year: 2014
Journal: Immunology
Title: Interleukin-2-mediated inhibition of dendritic cell development correlates with decreased CD135 expression and increased monocyte/macrophage precursors.
Volume: 143
Issue: 4
Pages: 640-50
Publication
First Author: Annesley CE
Year: 2018
Journal: Oncotarget
Title: Knock-in of the Wt1 R394W mutation causes MDS and cooperates with Flt3/ITD to drive aggressive myeloid neoplasms in mice.
Volume: 9
Issue: 82
Pages: 35313-35326
Publication
First Author: Kresinsky A
Year: 2019
Journal: Oncogene
Title: Lack of CD45 in FLT3-ITD mice results in a myeloproliferative phenotype, cortical porosity, and ectopic bone formation.
Volume: 38
Issue: 24
Pages: 4773-4787
Publication
First Author: Reckzeh K
Year: 2012
Journal: Leukemia
Title: Molecular and cellular effects of oncogene cooperation in a genetically accurate AML mouse model.
Volume: 26
Issue: 7
Pages: 1527-36
Publication
First Author: Bernot KM
Year: 2013
Journal: Blood
Title: Eradicating acute myeloid leukemia in a Mll(PTD/wt):Flt3(ITD/wt) murine model: a path to novel therapeutic approaches for human disease.
Volume: 122
Issue: 23
Pages: 3778-83
Publication
First Author: Rau R
Year: 2014
Journal: Exp Hematol
Title: NPMc+ cooperates with Flt3/ITD mutations to cause acute leukemia recapitulating human disease.
Volume: 42
Issue: 2
Pages: 101-13.e5
Publication
First Author: Ogawa M
Year: 1998
Journal: Exp Hematol
Title: Flt3/Flk-2 and c-Kit are not essential for the proliferation of B lymphoid progenitor cells in the bone marrow of the adult mouse.
Volume: 26
Issue: 6
Pages: 478-88
Publication
First Author: Metcalf D
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Murine hematopoietic blast colony-forming cells and their progeny have distinctive membrane marker profiles.
Volume: 106
Issue: 45
Pages: 19102-7
Publication
First Author: Dolence JJ
Year: 2011
Journal: Eur J Immunol
Title: Threshold levels of Flt3-ligand are required for the generation and survival of lymphoid progenitors and B-cell precursors.
Volume: 41
Issue: 2
Pages: 324-34
Publication
First Author: Benz C
Year: 2008
Journal: J Exp Med
Title: The stream of precursors that colonizes the thymus proceeds selectively through the early T lineage precursor stage of T cell development.
Volume: 205
Issue: 5
Pages: 1187-99
Publication
First Author: Chatterjee A
Year: 2014
Journal: Cell Rep
Title: Regulation of Stat5 by FAK and PAK1 in Oncogenic FLT3- and KIT-Driven Leukemogenesis.
Volume: 9
Issue: 4
Pages: 1333-48
Publication
First Author: Uren AG
Year: 2008
Journal: Cell
Title: Large-scale mutagenesis in p19(ARF)- and p53-deficient mice identifies cancer genes and their collaborative networks.
Volume: 133
Issue: 4
Pages: 727-41
Publication
First Author: Bogunovic M
Year: 2009
Journal: Immunity
Title: Origin of the lamina propria dendritic cell network.
Volume: 31
Issue: 3
Pages: 513-25
Publication
First Author: Percin GI
Year: 2018
Journal: Nat Commun
Title: CSF1R regulates the dendritic cell pool size in adult mice via embryo-derived tissue-resident macrophages.
Volume: 9
Issue: 1
Pages: 5279
Publication  
First Author: Worthington AK
Year: 2022
Journal: Development
Title: IL7Rα, but not Flk2, is required for hematopoietic stem cell reconstitution of tissue-resident lymphoid cells.
Volume: 149
Issue: 8
Publication
First Author: Spohr C
Year: 2022
Journal: Leukemia
Title: Gab2 deficiency prevents Flt3-ITD driven acute myeloid leukemia in vivo.
Volume: 36
Issue: 4
Pages: 970-982
Publication
First Author: Charlet A
Year: 2022
Journal: Leukemia
Title: The IL-3, IL-5, and GM-CSF common receptor beta chain mediates oncogenic activity of FLT3-ITD-positive AML.
Volume: 36
Issue: 3
Pages: 701-711
Publication
First Author: Shih AH
Year: 2017
Journal: Cancer Discov
Title: Combination Targeted Therapy to Disrupt Aberrant Oncogenic Signaling and Reverse Epigenetic Dysfunction in IDH2- and TET2-Mutant Acute Myeloid Leukemia.
Volume: 7
Issue: 5
Pages: 494-505
Publication
First Author: Greenblatt S
Year: 2012
Journal: Blood
Title: Knock-in of a FLT3/ITD mutation cooperates with a NUP98-HOXD13 fusion to generate acute myeloid leukemia in a mouse model.
Volume: 119
Issue: 12
Pages: 2883-94
Publication
First Author: Dovey OM
Year: 2017
Journal: Blood
Title: Molecular synergy underlies the co-occurrence patterns and phenotype of NPM1-mutant acute myeloid leukemia.
Volume: 130
Issue: 17
Pages: 1911-1922
Publication
First Author: Mead AJ
Year: 2017
Journal: J Exp Med
Title: Niche-mediated depletion of the normal hematopoietic stem cell reservoir by Flt3-ITD-induced myeloproliferation.
Volume: 214
Issue: 7
Pages: 2005-2021
Publication
First Author: Kim TG
Year: 2018
Journal: J Invest Dermatol
Title: Skin-Specific CD301b+ Dermal Dendritic Cells Drive IL-17-Mediated Psoriasis-Like Immune Response in Mice.
Volume: 138
Issue: 4
Pages: 844-853
Publication
First Author: Nobs SP
Year: 2015
Journal: Immunity
Title: PI3-Kinase-γ Has a Distinct and Essential Role in Lung-Specific Dendritic Cell Development.
Volume: 43
Issue: 4
Pages: 674-89
Publication
First Author: Ginhoux F
Year: 2009
Journal: J Exp Med
Title: The origin and development of nonlymphoid tissue CD103+ DCs.
Volume: 206
Issue: 13
Pages: 3115-30
Publication
First Author: Li Y
Year: 2023
Journal: Blood
Title: FLT3ITD drives context-specific changes in cell identity and variable interferon dependence during AML initiation.
Volume: 141
Issue: 12
Pages: 1442-1456
Publication
First Author: Agathocleous M
Year: 2017
Journal: Nature
Title: Ascorbate regulates haematopoietic stem cell function and leukaemogenesis.
Volume: 549
Issue: 7673
Pages: 476-481
Publication
First Author: Müller TA
Year: 2016
Journal: Leukemia
Title: Lineage-specific STAT5 target gene activation in hematopoietic progenitor cells predicts the FLT3(+)-mediated leukemic phenotype.
Volume: 30
Issue: 8
Pages: 1725-33
Publication
First Author: Svensson MN
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Murine germinal center B cells require functional Fms-like tyrosine kinase 3 signaling for IgG1 class-switch recombination.
Volume: 112
Issue: 48
Pages: E6644-53
Publication
First Author: Maraskovsky E
Year: 1996
Journal: J Exp Med
Title: Dramatic increase in the numbers of functionally mature dendritic cells in Flt3 ligand-treated mice: multiple dendritic cell subpopulations identified.
Volume: 184
Issue: 5
Pages: 1953-62
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Tzelepis K
Year: 2016
Journal: Cell Rep
Title: A CRISPR Dropout Screen Identifies Genetic Vulnerabilities and Therapeutic Targets in Acute Myeloid Leukemia.
Volume: 17
Issue: 4
Pages: 1193-1205
Publication
First Author: Tang Y
Year: 2015
Journal: Exp Hematol
Title: Coexpression of hyperactivated AKT1 with additional genes activated in leukemia drives hematopoietic progenitor cells to cell cycle block and apoptosis.
Volume: 43
Issue: 7
Pages: 554-64
Publication
First Author: Li Y
Year: 2016
Journal: Eur J Immunol
Title: A novel Flt3-deficient HIS mouse model with selective enhancement of human DC development.
Volume: 46
Issue: 5
Pages: 1291-9
Publication
First Author: Zeigler FC
Year: 1994
Journal: Blood
Title: Cellular and molecular characterization of the role of the flk-2/flt-3 receptor tyrosine kinase in hematopoietic stem cells.
Volume: 84
Issue: 8
Pages: 2422-30
Publication
First Author: Small D
Year: 1994
Journal: Proc Natl Acad Sci U S A
Title: STK-1, the human homolog of Flk-2/Flt-3, is selectively expressed in CD34+ human bone marrow cells and is involved in the proliferation of early progenitor/stem cells.
Volume: 91
Issue: 2
Pages: 459-63
Publication
First Author: Hunte BE
Year: 1996
Journal: J Immunol
Title: flk2/flt3 ligand is a potent cofactor for the growth of primitive B cell progenitors.
Volume: 156
Issue: 2
Pages: 489-96
Publication
First Author: Karsunky H
Year: 2008
Journal: Blood
Title: Flk2+ common lymphoid progenitors possess equivalent differentiation potential for the B and T lineages.
Volume: 111
Issue: 12
Pages: 5562-70
Publication
First Author: Mkonyi LE
Year: 2010
Journal: Am J Physiol Heart Circ Physiol
Title: Importance of lymph vessels in the transcapillary fluid balance in the gingiva studied in a transgenic mouse model.
Volume: 299
Issue: 2
Pages: H275-83
Publication
First Author: Finnon R
Year: 2012
Journal: Leukemia
Title: Flt3-ITD mutations in a mouse model of radiation-induced acute myeloid leukaemia.
Volume: 26
Issue: 6
Pages: 1445-6
GXD Expression    
Probe: MGI:1329083
Assay Type: RT-PCR
Annotation Date: 1999-02-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684620
Stage: TS20
Assay Id: MGI:1329612
Age: embryonic day 12.5
Image: 4
Specimen Label: +/+
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:1329083
Assay Type: RT-PCR
Annotation Date: 1999-02-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684620
Stage: TS20
Assay Id: MGI:1329612
Age: embryonic day 12.5
Image: 4
Specimen Label: +/-
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:1329083
Assay Type: RT-PCR
Annotation Date: 1999-02-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1684620
Stage: TS20
Assay Id: MGI:1329612
Age: embryonic day 12.5
Image: 4
Specimen Label: -/-
Detected: false
Specimen Num: 4
GXD Expression        
Probe: MGI:2652376
Assay Type: RT-PCR
Annotation Date: 2003-03-26
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1684622
Stage: TS22
Assay Id: MGI:2652402
Age: embryonic day 14.5
Specimen Label: PU.1 +/-
Specimen Num: 1
GXD Expression      
Probe: MGI:2662891
Assay Type: RT-PCR
Annotation Date: 2003-07-07
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1608515
Stage: TS15
Assay Id: MGI:2664564
Age: embryonic day 9.5
Specimen Label: E9.5 Yolk sac +/+
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:2662891
Assay Type: RT-PCR
Annotation Date: 2003-07-07
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1608515
Stage: TS15
Assay Id: MGI:2664564
Age: embryonic day 9.5
Specimen Label: E9.5 Yolk sac +/-
Detected: false
Specimen Num: 2
GXD Expression      
Probe: MGI:2662891
Assay Type: RT-PCR
Annotation Date: 2003-07-07
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1608515
Stage: TS15
Assay Id: MGI:2664564
Age: embryonic day 9.5
Specimen Label: E9.5 Yolk sac -/-
Detected: false
Specimen Num: 3
GXD Expression      
Probe: MGI:2662891
Assay Type: RT-PCR
Annotation Date: 2003-07-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684619
Stage: TS19
Assay Id: MGI:2664564
Age: embryonic day 11.5
Specimen Label: E11.5 Liver +/+
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:2662891
Assay Type: RT-PCR
Annotation Date: 2003-07-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684619
Stage: TS19
Assay Id: MGI:2664564
Age: embryonic day 11.5
Specimen Label: E11.5 Liver +/-
Detected: true
Specimen Num: 8
GXD Expression      
Probe: MGI:2662891
Assay Type: RT-PCR
Annotation Date: 2003-07-07
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1684619
Stage: TS19
Assay Id: MGI:2664564
Age: embryonic day 11.5
Specimen Label: E11.5 Liver -/-
Detected: false
Specimen Num: 9
GXD Expression      
Probe: MGI:2662891
Assay Type: RT-PCR
Annotation Date: 2003-07-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684619
Stage: TS19
Assay Id: MGI:2664564
Age: embryonic day 11.5
Specimen Label: E11.5 Liver +/+
Detected: true
Specimen Num: 10
GXD Expression      
Probe: MGI:2662891
Assay Type: RT-PCR
Annotation Date: 2003-07-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684619
Stage: TS19
Assay Id: MGI:2664564
Age: embryonic day 11.5
Specimen Label: E11.5 Liver +/-
Detected: true
Specimen Num: 11
GXD Expression      
Probe: MGI:2662891
Assay Type: RT-PCR
Annotation Date: 2003-07-07
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1684619
Stage: TS19
Assay Id: MGI:2664564
Age: embryonic day 11.5
Specimen Label: E11.5 Liver -/-
Detected: false
Specimen Num: 12
GXD Expression      
Probe: MGI:2662891
Assay Type: RT-PCR
Annotation Date: 2003-07-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684619
Stage: TS19
Assay Id: MGI:2664564
Age: embryonic day 11.5
Specimen Label: E11.5 Liver +/+
Detected: true
Specimen Num: 13
GXD Expression      
Probe: MGI:2662891
Assay Type: RT-PCR
Annotation Date: 2003-07-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684619
Stage: TS19
Assay Id: MGI:2664564
Age: embryonic day 11.5
Specimen Label: E11.5 Liver +/-
Detected: true
Specimen Num: 14
GXD Expression      
Probe: MGI:2662891
Assay Type: RT-PCR
Annotation Date: 2003-07-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684619
Stage: TS19
Assay Id: MGI:2664564
Age: embryonic day 11.5
Specimen Label: E11.5 Liver -/-
Detected: true
Specimen Num: 15
GXD Expression      
Probe: MGI:1329083
Assay Type: RT-PCR
Annotation Date: 2003-12-02
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1608513
Stage: TS13
Assay Id: MGI:2680306
Age: embryonic day 8.5
Specimen Label: 30
Detected: false
Specimen Num: 30