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Search results 101 to 200 out of 332 for Ikbke

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Hits by Pathway

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Type Details Score
GXD Expression
GXD Expression
   
Probe: MGI:5002103
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2851823
Stage: TS23
Assay Id: MGI:5542657
Age: embryonic day 15.5
Image: GUDMAP:10706
Specimen Label: GUDMAP:10706
Detected: false
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:5002103
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2760523
Stage: TS23
Assay Id: MGI:5542657
Age: embryonic day 15.5
Image: GUDMAP:10705
Specimen Label: GUDMAP:10705
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:5002103
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2760523
Stage: TS23
Assay Id: MGI:5542657
Age: embryonic day 15.5
Image: GUDMAP:10706
Specimen Label: GUDMAP:10706
Detected: false
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1480177
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1801023
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825554
Age: embryonic day 14.5
Image: euxassay_004923_08
Specimen Label: euxassay_004923_08
Detected: true
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1480177
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1801023
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825554
Age: embryonic day 14.5
Image: euxassay_004923_09
Specimen Label: euxassay_004923_09
Detected: true
Specimen Num: 6
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1480177
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1801023
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825554
Age: embryonic day 14.5
Image: euxassay_004923_10
Specimen Label: euxassay_004923_10
Detected: true
Specimen Num: 7
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1480177
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1801023
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825554
Age: embryonic day 14.5
Image: euxassay_004923_12
Specimen Label: euxassay_004923_12
Detected: true
Specimen Num: 9
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1480177
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1801023
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825554
Age: embryonic day 14.5
Image: euxassay_004923_13
Specimen Label: euxassay_004923_13
Detected: true
Specimen Num: 10
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1480177
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1801023
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825554
Age: embryonic day 14.5
Image: euxassay_004923_14
Specimen Label: euxassay_004923_14
Detected: true
Specimen Num: 11
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1480177
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1801023
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825554
Age: embryonic day 14.5
Image: euxassay_004923_15
Specimen Label: euxassay_004923_15
Detected: true
Specimen Num: 12
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1480177
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1801023
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825554
Age: embryonic day 14.5
Image: euxassay_004923_16
Specimen Label: euxassay_004923_16
Detected: true
Specimen Num: 13
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1480177
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1801023
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825554
Age: embryonic day 14.5
Image: euxassay_004923_17
Specimen Label: euxassay_004923_17
Detected: true
Specimen Num: 14
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:5002103
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2852723
Stage: TS23
Assay Id: MGI:5542657
Age: embryonic day 15.5
Image: GUDMAP:10705
Specimen Label: GUDMAP:10705
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:5002103
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2852723
Stage: TS23
Assay Id: MGI:5542657
Age: embryonic day 15.5
Image: GUDMAP:10706
Specimen Label: GUDMAP:10706
Detected: false
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:5002103
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2874723
Stage: TS23
Assay Id: MGI:5542657
Age: embryonic day 15.5
Image: GUDMAP:10706
Specimen Label: GUDMAP:10706
Detected: false
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1480177
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1754823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825554
Age: embryonic day 14.5
Image: euxassay_004923_07
Specimen Label: euxassay_004923_07
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1480177
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1754823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825554
Age: embryonic day 14.5
Image: euxassay_004923_08
Specimen Label: euxassay_004923_08
Detected: true
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1480177
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1754823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825554
Age: embryonic day 14.5
Image: euxassay_004923_09
Specimen Label: euxassay_004923_09
Detected: true
Specimen Num: 6
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1480177
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1754823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825554
Age: embryonic day 14.5
Image: euxassay_004923_10
Specimen Label: euxassay_004923_10
Detected: true
Specimen Num: 7
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1480177
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1754823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825554
Age: embryonic day 14.5
Image: euxassay_004923_11
Specimen Label: euxassay_004923_11
Detected: true
Specimen Num: 8
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1480177
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1754823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825554
Age: embryonic day 14.5
Image: euxassay_004923_17
Specimen Label: euxassay_004923_17
Detected: true
Specimen Num: 14
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1480177
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1754823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825554
Age: embryonic day 14.5
Image: euxassay_004923_18
Specimen Label: euxassay_004923_18
Detected: true
Specimen Num: 15
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1480177
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1754823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825554
Age: embryonic day 14.5
Image: euxassay_004923_19
Specimen Label: euxassay_004923_19
Detected: true
Specimen Num: 16
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1480177
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1784723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825554
Age: embryonic day 14.5
Image: euxassay_004923_11
Specimen Label: euxassay_004923_11
Detected: true
Specimen Num: 8
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1480177
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1784723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825554
Age: embryonic day 14.5
Image: euxassay_004923_12
Specimen Label: euxassay_004923_12
Detected: true
Specimen Num: 9
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1480177
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1784723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825554
Age: embryonic day 14.5
Image: euxassay_004923_13
Specimen Label: euxassay_004923_13
Detected: true
Specimen Num: 10
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1480177
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1784723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825554
Age: embryonic day 14.5
Image: euxassay_004923_14
Specimen Label: euxassay_004923_14
Detected: true
Specimen Num: 11
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1480177
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1784723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825554
Age: embryonic day 14.5
Image: euxassay_004923_15
Specimen Label: euxassay_004923_15
Detected: true
Specimen Num: 12
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:5002103
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2850023
Stage: TS23
Assay Id: MGI:5542657
Age: embryonic day 15.5
Image: GUDMAP:10705
Specimen Label: GUDMAP:10705
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:5002103
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2850023
Stage: TS23
Assay Id: MGI:5542657
Age: embryonic day 15.5
Image: GUDMAP:10706
Specimen Label: GUDMAP:10706
Detected: false
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:5002103
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:1796223
Stage: TS23
Assay Id: MGI:5542657
Age: embryonic day 15.5
Image: GUDMAP:10706
Specimen Label: GUDMAP:10706
Detected: false
Specimen Num: 2
•
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Publication
15210742 | J:91363
First Author: Hemmi H
Year: 2004
Journal: J Exp Med
Title: The roles of two IkappaB kinase-related kinases in lipopolysaccharide and double stranded RNA signaling and viral infection.
Volume: 199
Issue: 12
Pages: 1641-50
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Publication
17056502 | J:140538
First Author: Matsui K
Year: 2006
Journal: J Immunol
Title: Cutting edge: Role of TANK-binding kinase 1 and inducible IkappaB kinase in IFN responses against viruses in innate immune cells.
Volume: 177
Issue: 9
Pages: 5785-9
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Publication
32064021 | J:296497
 
First Author: Chai H
Year: 2020
Journal: Oxid Med Cell Longev
Title: IKK Epsilon Deficiency Attenuates Angiotensin II-Induced Abdominal Aortic Aneurysm Formation in Mice by Inhibiting Inflammation, Oxidative Stress, and Apoptosis.
Volume: 2020
Pages: 3602824
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Publication
27346349 | J:238517
First Author: Zhang J
Year: 2016
Journal: Cell Rep
Title: IκB Kinase ε Is an NFATc1 Kinase that Inhibits T Cell Immune Response.
Volume: 16
Issue: 2
Pages: 405-18
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Publication
23741427 | J:202115
First Author: Cao C
Year: 2013
Journal: PLoS One
Title: IKKε knockout prevents high fat diet induced arterial atherosclerosis and NF-κB signaling in mice.
Volume: 8
Issue: 5
Pages: e64930
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Publication
26899380 | J:234733
 
First Author: Xu J
Year: 2016
Journal: Nat Commun
Title: The REGγ-proteasome forms a regulatory circuit with IκBɛ and NFκB in experimental colitis.
Volume: 7
Pages: 10761
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Publication
24812431 | J:229836
First Author: Weissmann L
Year: 2014
Journal: Diabetes
Title: IKKε is key to induction of insulin resistance in the hypothalamus, and its inhibition reverses obesity.
Volume: 63
Issue: 10
Pages: 3334-45
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Publication
20507904 | J:173425
First Author: Moreno R
Year: 2010
Journal: Nucleic Acids Res
Title: Specification of the NF-kappaB transcriptional response by p65 phosphorylation and TNF-induced nuclear translocation of IKK epsilon.
Volume: 38
Issue: 18
Pages: 6029-44
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Publication
22065572 | J:178837
First Author: Perwitasari O
Year: 2011
Journal: J Biol Chem
Title: Inhibitor of κB kinase epsilon (IKK(epsilon)), STAT1, and IFIT2 proteins define novel innate immune effector pathway against West Nile virus infection.
Volume: 286
Issue: 52
Pages: 44412-23
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Publication
32220666 | J:286396
     
First Author: Gerbino V
Year: 2020
Journal: Neuron
Title: The Loss of TBK1 Kinase Activity in Motor Neurons or in All Cell Types Differentially Impacts ALS Disease Progression in SOD1 Mice.
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Publication
30853218 | J:286020
First Author: Tan Y
Year: 2019
Journal: Cell
Title: Innate Immune Signaling Organelles Display Natural and Programmable Signaling Flexibility.
Volume: 177
Issue: 2
Pages: 384-398.e11
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Publication
21357541 | J:170690
First Author: Maitra U
Year: 2011
Journal: J Immunol
Title: Low-dose endotoxin induces inflammation by selectively removing nuclear receptors and activating CCAAT/enhancer-binding protein δ.
Volume: 186
Issue: 7
Pages: 4467-73
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Publication
28481329 | J:259467
First Author: Wang S
Year: 2017
Journal: Nat Immunol
Title: YAP antagonizes innate antiviral immunity and is targeted for lysosomal degradation through IKKɛ-mediated phosphorylation.
Volume: 18
Issue: 7
Pages: 733-743
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Publication
34518217 | J:310703
 
First Author: Fischer FA
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: TBK1 and IKKε act like an OFF switch to limit NLRP3 inflammasome pathway activation.
Volume: 118
Issue: 38
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Publication
17327220 | J:121134
First Author: Guo B
Year: 2007
Journal: J Biol Chem
Title: Modulation of the interferon antiviral response by the TBK1/IKKi adaptor protein TANK.
Volume: 282
Issue: 16
Pages: 11817-26
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Publication
23396947 | J:193597
First Author: Bruni D
Year: 2013
Journal: J Immunol
Title: A novel IRAK1-IKKε signaling axis limits the activation of TAK1-IKKβ downstream of TLR3.
Volume: 190
Issue: 6
Pages: 2844-56
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Publication
26980769 | J:231832
First Author: Göktuna SI
Year: 2016
Journal: Cancer Res
Title: The Prosurvival IKK-Related Kinase IKKε Integrates LPS and IL17A Signaling Cascades to Promote Wnt-Dependent Tumor Development in the Intestine.
Volume: 76
Issue: 9
Pages: 2587-99
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Publication
24562310 | J:209894
First Author: Everts B
Year: 2014
Journal: Nat Immunol
Title: TLR-driven early glycolytic reprogramming via the kinases TBK1-IKKɛ supports the anabolic demands of dendritic cell activation.
Volume: 15
Issue: 4
Pages: 323-32
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Publication
22007846 | J:179219
First Author: Goh ET
Year: 2012
Journal: Biochem J
Title: Identification of the protein kinases that activate the E3 ubiquitin ligase Pellino 1 in the innate immune system.
Volume: 441
Issue: 1
Pages: 339-46
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Publication
37967220 | J:342970
First Author: Watanabe S
Year: 2023
Journal: Proc Natl Acad Sci U S A
Title: Mitochondria-associated membrane collapse impairs TBK1-mediated proteostatic stress response in ALS.
Volume: 120
Issue: 47
Pages: e2315347120
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Publication
32268090 | J:314406
First Author: Balka KR
Year: 2020
Journal: Cell Rep
Title: TBK1 and IKKε Act Redundantly to Mediate STING-Induced NF-κB Responses in Myeloid Cells.
Volume: 31
Issue: 1
Pages: 107492
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Publication
21822257 | J:176466
First Author: Bulek K
Year: 2011
Journal: Nat Immunol
Title: The inducible kinase IKKi is required for IL-17-dependent signaling associated with neutrophilia and pulmonary inflammation.
Volume: 12
Issue: 9
Pages: 844-52
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Publication
30902986 | J:273264
First Author: Zhao Y
Year: 2019
Journal: Nat Commun
Title: Microbial recognition by GEF-H1 controls IKKε mediated activation of IRF5.
Volume: 10
Issue: 1
Pages: 1349
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Publication
24591377 | J:209870
First Author: Alves BN
Year: 2014
Journal: J Immunol
Title: IκBε is a key regulator of B cell expansion by providing negative feedback on cRel and RelA in a stimulus-specific manner.
Volume: 192
Issue: 7
Pages: 3121-32
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Publication
18467330 | J:138116
First Author: Zhang M
Year: 2008
Journal: J Biol Chem
Title: Regulation of IkappaB kinase-related kinases and antiviral responses by tumor suppressor CYLD.
Volume: 283
Issue: 27
Pages: 18621-6
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Publication
27129230 | J:235021
First Author: Ren Y
Year: 2016
Journal: J Biol Chem
Title: The Type I Interferon-IRF7 Axis Mediates Transcriptional Expression of Usp25 Gene.
Volume: 291
Issue: 25
Pages: 13206-15
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Publication
24882218 | J:222665
First Author: Rajsbaum R
Year: 2014
Journal: Immunity
Title: Unanchored K48-linked polyubiquitin synthesized by the E3-ubiquitin ligase TRIM6 stimulates the interferon-IKKε kinase-mediated antiviral response.
Volume: 40
Issue: 6
Pages: 880-95
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Publication
30683688 | J:286517
 
First Author: Imanishi T
Year: 2019
Journal: Life Sci Alliance
Title: Reciprocal regulation of STING and TCR signaling by mTORC1 for T-cell activation and function.
Volume: 2
Issue: 1
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Publication
16286919 | J:112953
First Author: Ishii KJ
Year: 2006
Journal: Nat Immunol
Title: A Toll-like receptor-independent antiviral response induced by double-stranded B-form DNA.
Volume: 7
Issue: 1
Pages: 40-8
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Publication
25606824 | J:219715
 
First Author: Yu J
Year: 2015
Journal: Nat Commun
Title: Regulation of T-cell activation and migration by the kinase TBK1 during neuroinflammation.
Volume: 6
Pages: 6074
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Publication
33822771 | J:321001
 
First Author: Reilly SM
Year: 2021
Journal: J Clin Invest
Title: FGF21 is required for the metabolic benefits of IKKε/TBK1 inhibition.
Volume: 131
Issue: 10
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Publication
23023393 | J:188560
First Author: Jin J
Year: 2012
Journal: Nat Immunol
Title: The kinase TBK1 controls IgA class switching by negatively regulating noncanonical NF-κB signaling.
Volume: 13
Issue: 11
Pages: 1101-9
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Publication
20389019 | J:161476
First Author: Watanabe T
Year: 2010
Journal: J Clin Invest
Title: NOD1 contributes to mouse host defense against Helicobacter pylori via induction of type I IFN and activation of the ISGF3 signaling pathway.
Volume: 120
Issue: 5
Pages: 1645-62
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Publication
23142783 | J:190868
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First Author: Mouse Genome Informatics Scientific Curators
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First Author: Mouse Genome Informatics Scientific Curators
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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