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Search results 101 to 180 out of 180 for Mbl2

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Type Details Score
Publication
34031614 | J:314460
First Author: Cumpelik A
Year: 2021
Journal: Nat Immunol
Title: Dynamic regulation of B cell complement signaling is integral to germinal center responses.
Volume: 22
Issue: 6
Pages: 757-768
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Publication
23427256 | J:194520
First Author: Miwa T
Year: 2013
Journal: J Immunol
Title: Blocking properdin, the alternative pathway, and anaphylatoxin receptors ameliorates renal ischemia-reperfusion injury in decay-accelerating factor and CD59 double-knockout mice.
Volume: 190
Issue: 7
Pages: 3552-9
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Publication
20375621 | J:194455
First Author: Endo Y
Year: 2010
Journal: J Innate Immun
Title: Interactions of ficolin and mannose-binding lectin with fibrinogen/fibrin augment the lectin complement pathway.
Volume: 2
Issue: 1
Pages: 33-42
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Publication
19380618 | J:166493
First Author: Matthijsen RA
Year: 2009
Journal: Circulation
Title: Macrophage-specific expression of mannose-binding lectin controls atherosclerosis in low-density lipoprotein receptor-deficient mice.
Volume: 119
Issue: 16
Pages: 2188-95
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Publication
39226900 | J:354496
First Author: Stark K
Year: 2024
Journal: Immunity
Title: Antibodies and complement are key drivers of thrombosis.
Volume: 57
Issue: 9
Pages: 2140-2156.e10
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Publication
9525630 | J:46357
First Author: Golovkina TV
Year: 1998
Journal: J Virol
Title: A novel membrane protein is a mouse mammary tumor virus receptor.
Volume: 72
Issue: 4
Pages: 3066-71
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Publication
7592984 | J:30274
First Author: Epifano O
Year: 1995
Journal: J Biol Chem
Title: Mouse Zp1 encodes a zona pellucida protein homologous to egg envelope proteins in mammals and fish.
Volume: 270
Issue: 45
Pages: 27254-8
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Publication
10047541 | J:53149
First Author: Tenner AJ
Year: 1999
Journal: Curr Opin Immunol
Title: Membrane receptors for soluble defense collagens.
Volume: 11
Issue: 1
Pages: 34-41
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Publication
20870940 | J:165200
First Author: Banda NK
Year: 2010
Journal: J Immunol
Title: Essential role of complement mannose-binding lectin-associated serine proteases-1/3 in the murine collagen antibody-induced model of inflammatory arthritis.
Volume: 185
Issue: 9
Pages: 5598-606
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Publication
7894166 | J:22183
First Author: White RA
Year: 1994
Journal: Mamm Genome
Title: The murine mannose-binding protein genes (Mbl 1 and Mbl 2) localize to chromosomes 14 and 19.
Volume: 5
Issue: 12
Pages: 807-9
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Publication
9107690 | J:39608
First Author: Wright A
Year: 1997
Journal: Mamm Genome
Title: Mart1 is located on mouse chromosome 19 and is excluded as a candidate for ep and ru.
Volume: 8
Issue: 5
Pages: 377-8
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Publication
33927296 | J:306186
First Author: Pisko J
Year: 2021
Journal: Sci Rep
Title: Apoptotic cells in mouse blastocysts are eliminated by neighbouring blastomeres.
Volume: 11
Issue: 1
Pages: 9228
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Publication
21305474 | J:170493
First Author: Pfister S
Year: 2011
Journal: Int J Dev Biol
Title: Sox17-dependent gene expression and early heart and gut development in Sox17-deficient mouse embryos.
Volume: 55
Issue: 1
Pages: 45-58
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Publication
27689697 | J:235644
First Author: Wu Y
Year: 2016
Journal: PLoS Genet
Title: Mtu1-Mediated Thiouridine Formation of Mitochondrial tRNAs Is Required for Mitochondrial Translation and Is Involved in Reversible Infantile Liver Injury.
Volume: 12
Issue: 9
Pages: e1006355
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
30973865 | J:274872
First Author: Ingham NJ
Year: 2019
Journal: PLoS Biol
Title: Mouse screen reveals multiple new genes underlying mouse and human hearing loss.
Volume: 17
Issue: 4
Pages: e3000194
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Publication
- | J:237616
     
First Author: MGI and IMPC
Year: 2017
Journal: MGI Direct Data Submission
Title: MGI Curation of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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Publication
- | J:73065
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
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Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Allele
Mbl2<em1Smoc> | MGI:7290993
Name: mannose-binding lectin (protein C) 2; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
Mbl1<tm1.1(MBL2)Glst> | MGI:5705816
Name: mannose-binding lectin (protein A) 1; targeted mutation 1.1, Gregory L Stahl
Allele Type: Targeted
Attribute String: Inserted expressed sequence, Null/knockout
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Publication
16116208 | -
First Author: Hirano M
Year: 2005
Journal: J Immunol
Title: Mannan-binding protein blocks the activation of metalloproteases meprin alpha and beta.
Volume: 175
Issue: 5
Pages: 3177-85
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Publication
7634089 | -
First Author: Sheriff S
Year: 1994
Journal: Nat Struct Biol
Title: Human mannose-binding protein carbohydrate recognition domain trimerizes through a triple alpha-helical coiled-coil.
Volume: 1
Issue: 11
Pages: 789-94
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Publication
2691503 | -
First Author: Kawasaki N
Year: 1989
Journal: J Biochem
Title: A serum lectin (mannan-binding protein) has complement-dependent bactericidal activity.
Volume: 106
Issue: 3
Pages: 483-9
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Publication
14515269 | -
First Author: Nauta AJ
Year: 2003
Journal: Eur J Immunol
Title: Mannose-binding lectin engagement with late apoptotic and necrotic cells.
Volume: 33
Issue: 10
Pages: 2853-63
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Publication
1460414 | -
First Author: Matsushita M
Year: 1992
Journal: J Exp Med
Title: Activation of the classical complement pathway by mannose-binding protein in association with a novel C1s-like serine protease.
Volume: 176
Issue: 6
Pages: 1497-502
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Publication
8419490 | -
First Author: Ji YH
Year: 1993
Journal: J Immunol
Title: Activation of the C4 and C2 components of complement by a proteinase in serum bactericidal factor, Ra reactive factor.
Volume: 150
Issue: 2
Pages: 571-8
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Protein Domain
IPR037570 | Mannose-binding_protein_C
Type: Family
Description: Mannose-binding protein C (MBL2) is a calcium-dependent lectin involved in innate immune defence. It binds to oligosaccharides (mannose, fucose and N-acetylglucosamine) on the surface of micro-organisms and initiates complement activation of the lectin pathway []. It also binds to late apoptotic cells, enabling their uptake by macrophages []. MBL2 forms a homotrimer []which then binds to mannan-binding lectin-associated serine peptidases, leading to their activation and cleavage of complement components C2 and C4 to form the C3/C5 convertase [, ]. MBL2 expressed on the brush border epithelial cells of kidney-proximal tubules interacts with meprin precursors, preventing activation []. The tertiary structure of MBL2 has been solved, and the protein contains a collagen-like and a C-typelectin domain [].
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Allele
Mbl1<tm1Kata> | MGI:3043898
Name: mannose-binding lectin (protein A) 1; targeted mutation 1, Kazue Takahashi
Allele Type: Targeted
Attribute String: Null/knockout
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Strain
MGI:5787990 | STOCK Mbl1<tm1.1(MBL2)Glst>/J
Attribute String: mutant stock, targeted mutation
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Publication
12270724 | J:90437
First Author: Takahashi K
Year: 2002
Journal: Microbes Infect
Title: Lack of mannose-binding lectin-A enhances survival in a mouse model of acute septic peritonitis.
Volume: 4
Issue: 8
Pages: 773-84
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Genotype
Genotype
Symbol: Mbl1/Mbl1
Background: involves: 129S4/SvJae * C57BL/6J
Zygosity: hm
Has Mutant Allele: true
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Strain
MGI:3618354 | B6.129S4-Mbl1<tm1Kata> Mbl2<tm1Kata>/J
Attribute String: congenic, mutant strain, targeted mutation
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Genotype
Genotype
Symbol: Mbl1/Mbl1 Mbl2/Mbl2
Background: involves: 129 * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Mbl1/Mbl1 Mbl2/Mbl2
Background: involves: 129 * C57BL/6J
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Fcna/Fcna Mbl1/Mbl1 Mbl2/Mbl2
Background: involves: 129S4/SvJae
Zygosity: cx
Has Mutant Allele: true
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Allele
dblr | MGI:2654910
 
Name: doubleridge
Allele Type: Transgenic
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Publication
38050344 | J:346996
First Author: Khor AHP
Year: 2024
Journal: Cancer Sci
Title: Regulation of the innate immune response and gut microbiome by p53.
Volume: 115
Issue: 1
Pages: 184-196
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Publication
20639398 | J:163634
First Author: Freudenberg J
Year: 2010
Journal: Hum Mol Genet
Title: Locus category based analysis of a large genome-wide association study of rheumatoid arthritis.
Volume: 19
Issue: 19
Pages: 3863-72
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Publication
16982912 | J:139312
First Author: Zhang M
Year: 2006
Journal: J Immunol
Title: Activation of the lectin pathway by natural IgM in a model of ischemia/reperfusion injury.
Volume: 177
Issue: 7
Pages: 4727-34
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Publication
17613296 | J:142933
First Author: MacDonald BT
Year: 2007
Journal: Bone
Title: Bone mass is inversely proportional to Dkk1 levels in mice.
Volume: 41
Issue: 3
Pages: 331-9
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Strain
MGI:4440945 | B6.SJL-dblr/Mmnc
Attribute String: transgenic, mutant strain, deletion, congenic
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Strain
MGI:5652429 | (C57BL/6J × SJL/J)F2-dblr/+
Attribute String: F2 hybrid, insertion, mutant stock, transgenic
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Strain
MGI:4440943 | C3Fe.SJL(B6)-dblr/Mmnc
Attribute String: mutant strain, congenic, transgenic
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Strain
MGI:2683534 | SJL/J-dblr
Attribute String: mutant strain
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Publication
12648495 | J:82633
First Author: Adamska M
Year: 2003
Journal: Dev Biol
Title: Doubleridge, a mouse mutant with defective compaction of the apical ectodermal ridge and normal dorsal-ventral patterning of the limb.
Volume: 255
Issue: 2
Pages: 350-62
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Publication
37263344 | J:339662
First Author: Sung EA
Year: 2023
Journal: Am J Pathol
Title: Dickkopf1 Promotes Pulmonary Fibrosis upon Bleomycin-Induced Lung Injury.
Volume: 193
Issue: 9
Pages: 1130-1142
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Publication
21304589 | J:169552
First Author: Matrisciano F
Year: 2011
Journal: PLoS One
Title: Induction of the Wnt antagonist Dickkopf-1 is involved in stress-induced hippocampal damage.
Volume: 6
Issue: 1
Pages: e16447
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Genotype
Genotype
Symbol: dblr/dblr
Background: involves: C57BL/6J * SJL/J
Zygosity: hm
Has Mutant Allele: true
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Protein
P41317
Organism: Mus musculus/domesticus
Length: 244  
Fragment?: false
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Protein
Q3UEK1
Organism: Mus musculus/domesticus
Length: 244  
Fragment?: false
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Publication
15242796 | J:92327
First Author: Adamska M
Year: 2004
Journal: Dev Biol
Title: En1 and Wnt7a interact with Dkk1 during limb development in the mouse.
Volume: 272
Issue: 1
Pages: 134-44
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Publication
17485663 | J:121840
First Author: Nimmerjahn F
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Agalactosylated IgG antibodies depend on cellular Fc receptors for in vivo activity.
Volume: 104
Issue: 20
Pages: 8433-7
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Publication
26872695 | J:263587
First Author: Chae WJ
Year: 2016
Journal: Immunity
Title: The Wnt Antagonist Dickkopf-1 Promotes Pathological Type 2 Cell-Mediated Inflammation.
Volume: 44
Issue: 2
Pages: 246-58
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Publication
16245025 | J:102036
First Author: Bergren SK
Year: 2005
Journal: Mamm Genome
Title: Genetic modifiers affecting severity of epilepsy caused by mutation of sodium channel Scn2a.
Volume: 16
Issue: 9
Pages: 683-90
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Publication
28556921 | J:245604
First Author: Chae WJ
Year: 2017
Journal: Immunology
Title: Membrane-bound Dickkopf-1 in Foxp3+ regulatory T cells suppresses T-cell-mediated autoimmune colitis.
Volume: 152
Issue: 2
Pages: 265-275
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