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Search results 101 to 200 out of 216 for Numa1

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Type Details Score
GXD Expression
GXD Expression
Probe: MGI:6864131
Assay Type: Immunohistochemistry
Annotation Date: 2022-02-03
Strength: Present
Sex: Female
Emaps: EMAPS:3575528
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6864139
Age: postnatal adult
Image: 3E/F
Note: After germinal vesicle breakdown, expression sarting to condense around chromoatin.
Specimen Label: 3E/F
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:6864131
Assay Type: Immunohistochemistry
Annotation Date: 2022-02-03
Strength: Present
Sex: Female
Emaps: EMAPS:3575528
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6864139
Age: postnatal adult
Image: 3e/f
Note: Expression much wider compared to that of RIC8 (Ric8a).
Specimen Label: 3e/f
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
Probe: MGI:6864131
Assay Type: Immunohistochemistry
Annotation Date: 2022-02-03
Strength: Present
Sex: Female
Emaps: EMAPS:3102528
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6864139
Age: postnatal adult
Image: 5B/C
Note: When chromosomes segregate, expression translocated to spindle midzone.
Specimen Label: 5B/C
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
Probe: MGI:6864131
Assay Type: Immunohistochemistry
Annotation Date: 2022-02-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160362
Pattern: Regionally restricted
Stage: TS02
Assay Id: MGI:6864139
Age: embryonic day 1.0
Image: 7K/L
Note: Expression in nucleus of blastomeres. No overlap with RIC8 (Ric8a) in cortex region.
Specimen Label: 7K/L
Detected: true
Specimen Num: 8
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Publication
31577227 | J:290859
   
First Author: Morrow A
Year: 2019
Journal: Elife
Title: Regulated spindle orientation buffers tissue growth in the epidermis.
Volume: 8
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Publication
26766442 | J:239972
First Author: Chiu CWN
Year: 2016
Journal: Dev Cell
Title: SAPCD2 Controls Spindle Orientation and Asymmetric Divisions by Negatively Regulating the Gαi-LGN-NuMA Ternary Complex.
Volume: 36
Issue: 1
Pages: 50-62
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Publication
28469279 | J:275317
First Author: Magescas J
Year: 2017
Journal: Sci Rep
Title: Spindle pole cohesion requires glycosylation-mediated localization of NuMA.
Volume: 7
Issue: 1
Pages: 1474
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Publication
18408763 | J:138508
First Author: Sukhai MA
Year: 2008
Journal: Oncogene
Title: Evidence of functional interaction between NuMA-RARalpha and RXRalpha in an in vivo model of acute promyelocytic leukemia.
Volume: 27
Issue: 34
Pages: 4666-77
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Publication
25936915 | J:306588
First Author: Zhao B
Year: 2015
Journal: Cell Stem Cell
Title: Filia Is an ESC-Specific Regulator of DNA Damage Response and Safeguards Genomic Stability.
Volume: 16
Issue: 6
Pages: 684-98
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Publication
18331714 | J:204810
First Author: Wang X
Year: 2008
Journal: Dev Cell
Title: sSgo1, a major splice variant of Sgo1, functions in centriole cohesion where it is regulated by Plk1.
Volume: 14
Issue: 3
Pages: 331-41
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Publication
34432485 | J:324129
First Author: Moreci RS
Year: 2021
Journal: Mol Biol Cell
Title: KIF18B is a cell type-specific regulator of spindle orientation in the epidermis.
Volume: 32
Issue: 21
Pages: ar29
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Publication
21098114 | J:166997
First Author: Poulson ND
Year: 2010
Journal: J Cell Biol
Title: Robust control of mitotic spindle orientation in the developing epidermis.
Volume: 191
Issue: 5
Pages: 915-22
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Publication
25139855 | J:214812
First Author: Chaffee BR
Year: 2014
Journal: Development
Title: Nuclear removal during terminal lens fiber cell differentiation requires CDK1 activity: appropriating mitosis-related nuclear disassembly.
Volume: 141
Issue: 17
Pages: 3388-98
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Publication
26062014 | J:237701
First Author: Saare M
Year: 2015
Journal: PLoS One
Title: Expression Pattern and Localization Dynamics of Guanine Nucleotide Exchange Factor RIC8 during Mouse Oogenesis.
Volume: 10
Issue: 6
Pages: e0129131
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Publication
28716713 | J:249114
First Author: Cavalheiro GR
Year: 2017
Journal: Dev Biol
Title: N-myc regulates growth and fiber cell differentiation in lens development.
Volume: 429
Issue: 1
Pages: 105-117
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Publication
21246661 | J:167828
First Author: El-Hashash AH
Year: 2011
Journal: Dev Dyn
Title: Cell polarity and spindle orientation in the distal epithelium of embryonic lung.
Volume: 240
Issue: 2
Pages: 441-5
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Publication
26765568 | J:229900
   
First Author: Seldin L
Year: 2016
Journal: Elife
Title: NuMA-microtubule interactions are critical for spindle orientation and the morphogenesis of diverse epidermal structures.
Volume: 5
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Publication
11092755 | J:106641
First Author: Hilditch-Maguire P
Year: 2000
Journal: Hum Mol Genet
Title: Huntingtin: an iron-regulated protein essential for normal nuclear and perinuclear organelles.
Volume: 9
Issue: 19
Pages: 2789-97
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Publication
21429982 | J:171221
First Author: Croyle MJ
Year: 2011
Journal: Development
Title: Role of epidermal primary cilia in the homeostasis of skin and hair follicles.
Volume: 138
Issue: 9
Pages: 1675-85
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Publication
37143315 | J:338401
     
First Author: Nutter CA
Year: 2023
Journal: Brain
Title: Choroid plexus mis-splicing and altered cerebrospinal fluid composition in myotonic dystrophy type 1.
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Publication
19332887 | J:147346
First Author: Lake BB
Year: 2009
Journal: J Cell Biol
Title: Strabismus regulates asymmetric cell divisions and cell fate determination in the mouse brain.
Volume: 185
Issue: 1
Pages: 59-66
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Publication
24749073 | J:309675
First Author: Elias S
Year: 2014
Journal: Stem Cell Reports
Title: Huntingtin regulates mammary stem cell division and differentiation.
Volume: 2
Issue: 4
Pages: 491-506
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Publication
36973253 | J:334512
First Author: He S
Year: 2023
Journal: Nat Commun
Title: Distinct dynein complexes defined by DYNLRB1 and DYNLRB2 regulate mitotic and male meiotic spindle bipolarity.
Volume: 14
Issue: 1
Pages: 1715
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Publication
33013468 | J:297684
 
First Author: Hooper JE
Year: 2020
Journal: Front Physiol
Title: An Alternative Splicing Program for Mouse Craniofacial Development.
Volume: 11
Pages: 1099
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Publication
26876178 | J:315122
First Author: Passer D
Year: 2016
Journal: Cell Rep
Title: Atypical Protein Kinase C-Dependent Polarized Cell Division Is Required for Myocardial Trabeculation.
Volume: 14
Issue: 7
Pages: 1662-1672
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Publication
30923192 | J:277726
 
First Author: Lecland N
Year: 2019
Journal: Life Sci Alliance
Title: Epidermal development requires ninein for spindle orientation and cortical microtubule organization.
Volume: 2
Issue: 2
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Publication
33899739 | J:308321
   
First Author: Lau EO
Year: 2021
Journal: Elife
Title: DIAPH3 deficiency links microtubules to mitotic errors, defective neurogenesis, and brain dysfunction.
Volume: 10
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Publication
36685938 | J:332918
 
First Author: Cai S
Year: 2022
Journal: Front Genet
Title: Transcriptomic analysis of the upper lip and primary palate development in mice.
Volume: 13
Pages: 1039850
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Publication
32492419 | J:306456
First Author: Farini D
Year: 2020
Journal: Cell Rep
Title: A Dynamic Splicing Program Ensures Proper Synaptic Connections in the Developing Cerebellum.
Volume: 31
Issue: 9
Pages: 107703
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Publication
33798452 | J:314103
First Author: Ulmke PA
Year: 2021
Journal: Stem Cell Reports
Title: Molecular Profiling Reveals Involvement of ESCO2 in Intermediate Progenitor Cell Maintenance in the Developing Mouse Cortex.
Volume: 16
Issue: 4
Pages: 968-984
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Publication
11180952 | J:67747
First Author: Thut CJ
Year: 2001
Journal: Dev Biol
Title: A large-scale in situ screen provides molecular evidence for the induction of eye anterior segment structures by the developing lens.
Volume: 231
Issue: 1
Pages: 63-76
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Publication
10725249 | J:60984
First Author: Ko MS
Year: 2000
Journal: Development
Title: Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development.
Volume: 127
Issue: 8
Pages: 1737-49
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Publication
- | J:73065
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
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Publication
12904583 | J:85162
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
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Publication
17967808 | J:152068
First Author: Friedel RH
Year: 2007
Journal: Brief Funct Genomic Proteomic
Title: EUCOMM--the European conditional mouse mutagenesis program.
Volume: 6
Issue: 3
Pages: 180-5
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Publication
- | J:265051
     
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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Publication
12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
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Publication
34321999 | J:313619
 
First Author: Bedogni F
Year: 2021
Journal: Front Mol Neurosci
Title: Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development.
Volume: 14
Pages: 686034
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Publication
- | J:57656
     
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Protein Domain
IPR021187 | Band_41_protein_chordates
Type: Family
Description: Protein 4.1 is a major structural element of the erythrocyte membrane skeleton. It plays a key role in regulating physical properties of the membrane, such as mechanical stability and de-formability, by stabilising spectrin-actin interactions [, , ]. It is required for dynein-dynactin complex and NUMA1 recruitment at the mitotic cell cortex during anaphase [].The protein has been shown to associate with the nuclear mitotic apparatus, the contractile apparatus and tight junctions. Defects in this protein can cause elliptocytosis type 1 and hereditary pyropoikilocytosis.Note: Band 4.1 and Band 7 () proteins refer to human erythrocyte membrane proteins separated by SDS polyacrylamide gels and stained with coomassie blue [].
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Publication
11017195 | -
First Author: Han BG
Year: 2000
Journal: Nat Struct Biol
Title: Protein 4.1R core domain structure and insights into regulation of cytoskeletal organization.
Volume: 7
Issue: 10
Pages: 871-5
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Publication
1647028 | -
First Author: Subrahmanyam G
Year: 1991
Journal: Proc Natl Acad Sci U S A
Title: Phosphorylation of protein 4.1 on tyrosine-418 modulates its function in vitro.
Volume: 88
Issue: 12
Pages: 5222-6
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Publication
23870127 | -
First Author: Kiyomitsu T
Year: 2013
Journal: Cell
Title: Cortical dynein and asymmetric membrane elongation coordinately position the spindle in anaphase.
Volume: 154
Issue: 2
Pages: 391-402
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Protein
Q9EPM7
Organism: Mus musculus/domesticus
Length: 159  
Fragment?: true
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Protein
A0A1W2P8C0
Organism: Mus musculus/domesticus
Length: 204  
Fragment?: true
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Protein
Q9EPM8
Organism: Mus musculus/domesticus
Length: 204  
Fragment?: true
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Publication
9598318 | -
First Author: Parra M
Year: 1998
Journal: Genomics
Title: Cloning and characterization of 4.1G (EPB41L2), a new member of the skeletal protein 4.1 (EPB41) gene family.
Volume: 49
Issue: 2
Pages: 298-306
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Protein Domain
IPR030546 | E41L2
Type: Family
Description: This entry represents band 4.1-like protein 2 []. It shares protein sequence similarity with Band 4.1 protein. Its function is not clear.Protein 4.1 is a major structural element of the erythrocyte membrane skeleton. It plays a key role in regulating physical properties of the membrane, such as mechanical stability and de-formability, by stabilising spectrin-actin interactions [, , ]. It is required for dynein-dynactin complex and NUMA1 recruitment at the mitotic cell cortex during anaphase [].The protein has been shown to associate with the nuclear mitotic apparatus, the contractile apparatus and tight junctions. Defects in this protein can cause elliptocytosis type 1 and hereditary pyropoikilocytosis.Note: Band 4.1 and Band 7 () proteins refer to human erythrocyte membrane proteins separated by SDS polyacrylamide gels and stained with coomassie blue [].
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Publication
11003675 | -
First Author: Hung LY
Year: 2000
Journal: Mol Cell Biol
Title: Protein 4.1 R-135 interacts with a novel centrosomal protein (CPAP) which is associated with the gamma-tubulin complex.
Volume: 20
Issue: 20
Pages: 7813-25
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Protein
A0A1W2P6H2
Organism: Mus musculus/domesticus
Length: 131  
Fragment?: true
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Protein
B6ZHC3
Organism: Mus musculus/domesticus
Length: 184  
Fragment?: true
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Protein
Q8BSR4
Organism: Mus musculus/domesticus
Length: 114  
Fragment?: true
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Protein
Q7TPN6
Organism: Mus musculus/domesticus
Length: 297  
Fragment?: false
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Protein
B6ZHC2
Organism: Mus musculus/domesticus
Length: 317  
Fragment?: true
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Publication
4326772 | -
First Author: Fairbanks G
Year: 1971
Journal: Biochemistry
Title: Electrophoretic analysis of the major polypeptides of the human erythrocyte membrane.
Volume: 10
Issue: 13
Pages: 2606-17
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Protein
Q3V048
Organism: Mus musculus/domesticus
Length: 172  
Fragment?: false
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Protein
F7BUB8
Organism: Mus musculus/domesticus
Length: 250  
Fragment?: true
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Protein
F6S4K9
Organism: Mus musculus/domesticus
Length: 375  
Fragment?: true
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Protein
A0A1W2P7I2
Organism: Mus musculus/domesticus
Length: 201  
Fragment?: false
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Protein
A0A1D5RLV1
Organism: Mus musculus/domesticus
Length: 476  
Fragment?: true
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Protein
A2A842
Organism: Mus musculus/domesticus
Length: 769  
Fragment?: false
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Protein
Q811C0
Organism: Mus musculus/domesticus
Length: 474  
Fragment?: true
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Protein
Q3UH12
Organism: Mus musculus/domesticus
Length: 476  
Fragment?: true
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Protein
P48193
Organism: Mus musculus/domesticus
Length: 858  
Fragment?: false
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Protein
O70318
Organism: Mus musculus/domesticus
Length: 988  
Fragment?: false
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Protein
Q80UE4
Organism: Mus musculus/domesticus
Length: 794  
Fragment?: false
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Protein
Q811B2
Organism: Mus musculus/domesticus
Length: 689  
Fragment?: false
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Protein
B6ZHD0
Organism: Mus musculus/domesticus
Length: 988  
Fragment?: false
•
•
•
•
•
Protein
A2AD32
Organism: Mus musculus/domesticus
Length: 767  
Fragment?: false
•
•
•
•
•
Protein
B6ZHC5
Organism: Mus musculus/domesticus
Length: 794  
Fragment?: false
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•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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