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Search results 101 to 200 out of 1964 for Olig2

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Type Details Score
Publication
First Author: Jiang M
Year: 2020
Journal: Mol Brain
Title: WNT signaling suppresses oligodendrogenesis via Ngn2-dependent direct inhibition of Olig2 expression.
Volume: 13
Issue: 1
Pages: 155
Publication
First Author: Wang SZ
Year: 2006
Journal: Development
Title: An oligodendrocyte-specific zinc-finger transcription regulator cooperates with Olig2 to promote oligodendrocyte differentiation.
Volume: 133
Issue: 17
Pages: 3389-98
Publication
First Author: Meijer DH
Year: 2014
Journal: J Neurosci
Title: An amino terminal phosphorylation motif regulates intranuclear compartmentalization of Olig2 in neural progenitor cells.
Volume: 34
Issue: 25
Pages: 8507-18
Publication
First Author: Setoguchi T
Year: 2004
Journal: J Cell Biol
Title: Nuclear export of OLIG2 in neural stem cells is essential for ciliary neurotrophic factor-induced astrocyte differentiation.
Volume: 166
Issue: 7
Pages: 963-8
Publication  
First Author: Chen LP
Year: 2012
Journal: Neuroscience
Title: Regulation of Olig2 during astroglial differentiation in the subventricular zone of a cuprizone-induced demyelination mouse model.
Volume: 221
Pages: 96-107
Publication
First Author: Takebayashi H
Year: 2002
Journal: Mech Dev
Title: Non-overlapping expression of Olig3 and Olig2 in the embryonic neural tube.
Volume: 113
Issue: 2
Pages: 169-74
Publication
First Author: Chen Y
Year: 2008
Journal: J Neurosci
Title: The basic helix-loop-helix transcription factor olig2 is critical for reactive astrocyte proliferation after cortical injury.
Volume: 28
Issue: 43
Pages: 10983-9
Publication  
First Author: Ju J
Year: 2016
Journal: Sci Rep
Title: Olig2 regulates Purkinje cell generation in the early developing mouse cerebellum.
Volume: 6
Pages: 30711
Publication
First Author: Zhang K
Year: 2022
Journal: Nat Commun
Title: The Oligodendrocyte Transcription Factor 2 OLIG2 regulates transcriptional repression during myelinogenesis in rodents.
Volume: 13
Issue: 1
Pages: 1423
Publication
First Author: Mei F
Year: 2013
Journal: J Neurosci
Title: Stage-specific deletion of Olig2 conveys opposing functions on differentiation and maturation of oligodendrocytes.
Volume: 33
Issue: 19
Pages: 8454-62
Publication
First Author: Furusho M
Year: 2006
Journal: Dev Biol
Title: Involvement of the Olig2 transcription factor in cholinergic neuron development of the basal forebrain.
Volume: 293
Issue: 2
Pages: 348-57
Publication
First Author: Sagner A
Year: 2018
Journal: PLoS Biol
Title: Olig2 and Hes regulatory dynamics during motor neuron differentiation revealed by single cell transcriptomics.
Volume: 16
Issue: 2
Pages: e2003127
Publication
First Author: Lee SK
Year: 2005
Journal: Genes Dev
Title: Olig2 and Ngn2 function in opposition to modulate gene expression in motor neuron progenitor cells.
Volume: 19
Issue: 2
Pages: 282-94
Publication
First Author: Zuo H
Year: 2018
Journal: J Neurosci
Title: Age-Dependent Decline in Fate Switch from NG2 Cells to Astrocytes After Olig2 Deletion.
Volume: 38
Issue: 9
Pages: 2359-2371
Publication
First Author: Buffo A
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: Expression pattern of the transcription factor Olig2 in response to brain injuries: implications for neuronal repair.
Volume: 102
Issue: 50
Pages: 18183-8
Publication
First Author: Cassiani-Ingoni R
Year: 2006
Journal: Exp Neurol
Title: Cytoplasmic translocation of Olig2 in adult glial progenitors marks the generation of reactive astrocytes following autoimmune inflammation.
Volume: 201
Issue: 2
Pages: 349-58
Publication
First Author: Liu Z
Year: 2007
Journal: Dev Biol
Title: Induction of oligodendrocyte differentiation by Olig2 and Sox10: evidence for reciprocal interactions and dosage-dependent mechanisms.
Volume: 302
Issue: 2
Pages: 683-93
GXD Expression  
Probe: MGI:7380629
Assay Type: Immunohistochemistry
Annotation Date: 2022-11-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1616415
Pattern: Regionally restricted
Stage: TS15
Assay Id: MGI:7380674
Age: embryonic day 9.5
Note: Expression in ventral neural tube
Specimen Label: S2A Olig2 WT
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:7380629
Assay Type: Immunohistochemistry
Annotation Date: 2022-11-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1616415
Pattern: Regionally restricted
Stage: TS15
Assay Id: MGI:7380674
Age: embryonic day 9.5
Specimen Label: S2A Olig2 bromi
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:7380629
Assay Type: Immunohistochemistry
Annotation Date: 2022-11-09
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1616415
Stage: TS15
Assay Id: MGI:7380674
Age: embryonic day 9.5
Specimen Label: S2A Olig2 Ptch1
Detected: false
Specimen Num: 3
GXD Expression  
Probe: MGI:7380629
Assay Type: Immunohistochemistry
Annotation Date: 2022-11-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1616415
Pattern: Regionally restricted
Stage: TS15
Assay Id: MGI:7380674
Age: embryonic day 9.5
Note: Expression domain not expanded dorsally.
Specimen Label: S2A Olig2 bromi,Ptch1
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:7380629
Assay Type: Immunohistochemistry
Annotation Date: 2022-11-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1616417
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:7380674
Age: embryonic day 10.5
Note: Expression in ventral neural tube.
Specimen Label: S2C Olig2 WT
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:7380629
Assay Type: Immunohistochemistry
Annotation Date: 2022-11-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1616417
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:7380674
Age: embryonic day 10.5
Specimen Label: S2C Olig2 bromi
Detected: true
Specimen Num: 6
GXD Expression  
Probe: MGI:7380629
Assay Type: Immunohistochemistry
Annotation Date: 2022-11-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1616417
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:7380674
Age: embryonic day 10.5
Note: Expression domain shifted compared to wild type.
Specimen Label: S2C Olig2 Rab23opb2
Detected: true
Specimen Num: 7
GXD Expression  
Probe: MGI:7380629
Assay Type: Immunohistochemistry
Annotation Date: 2022-11-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1616417
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:7380674
Age: embryonic day 10.5
Note: Authors report same dorsalized phenotype as in bromi single mutants.
Specimen Label: S2C Olig2 bromi,Rab23opb2
Detected: true
Specimen Num: 8
GXD Expression      
Probe: MGI:7606835
Assay Type: Immunohistochemistry
Annotation Date: 2024-02-27
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1616515
Stage: TS15
Assay Id: MGI:7606869
Age: embryonic day 9.5
Specimen Label: 4F +/+ Olig2 (left)
Detected: false
Specimen Num: 1
GXD Expression  
Probe: MGI:7606835
Assay Type: Immunohistochemistry
Annotation Date: 2024-02-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1616515
Pattern: Regionally restricted
Stage: TS15
Assay Id: MGI:7606869
Age: embryonic day 9.5
Note: Expression expanded into floor plate.
Specimen Label: 4F -/- Olig2 (left)
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:7606835
Assay Type: Immunohistochemistry
Annotation Date: 2024-02-27
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1616515
Stage: TS15
Assay Id: MGI:7606869
Age: embryonic day 9.5
Specimen Label: 4F +/+ Olig2 (right)
Detected: false
Specimen Num: 3
GXD Expression  
Probe: MGI:7606835
Assay Type: Immunohistochemistry
Annotation Date: 2024-02-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1616515
Pattern: Regionally restricted
Stage: TS15
Assay Id: MGI:7606869
Age: embryonic day 9.5
Note: Expression expanded into floor plate.
Specimen Label: 4F -/- Olig2 (right)
Detected: true
Specimen Num: 4
Publication
First Author: Kaltezioti V
Year: 2014
Journal: J Neurosci
Title: Prox1 regulates Olig2 expression to modulate binary fate decisions in spinal cord neurons.
Volume: 34
Issue: 47
Pages: 15816-31
Publication
First Author: Hayashi S
Year: 2023
Journal: J Neurochem
Title: OLIG2 is an in vivo bookmarking transcription factor in the developing neural tube in mouse.
Volume: 165
Issue: 3
Pages: 303-317
Publication
First Author: Matsumoto S
Year: 2016
Journal: Dev Biol
Title: Brg1 directly regulates Olig2 transcription and is required for oligodendrocyte progenitor cell specification.
Volume: 413
Issue: 2
Pages: 173-87
Publication
First Author: Wang YZ
Year: 2020
Journal: Cell Mol Life Sci
Title: Olig2 regulates terminal differentiation and maturation of peripheral olfactory sensory neurons.
Volume: 77
Issue: 18
Pages: 3597-3609
Publication
First Author: Mehta S
Year: 2011
Journal: Cancer Cell
Title: The central nervous system-restricted transcription factor Olig2 opposes p53 responses to genotoxic damage in neural progenitors and malignant glioma.
Volume: 19
Issue: 3
Pages: 359-71
Publication
First Author: Shibasaki K
Year: 2007
Journal: Gene Expr Patterns
Title: Expression of the basic helix-loop-factor Olig2 in the developing retina: Olig2 as a new marker for retinal progenitors and late-born cells.
Volume: 7
Issue: 1-2
Pages: 57-65
Publication
First Author: Chakrabarti L
Year: 2010
Journal: Nat Neurosci
Title: Olig1 and Olig2 triplication causes developmental brain defects in Down syndrome.
Volume: 13
Issue: 8
Pages: 927-34
Publication
First Author: Marumo T
Year: 2013
Journal: Neurosci Res
Title: Notch signaling regulates nucleocytoplasmic Olig2 translocation in reactive astrocytes differentiation after ischemic stroke.
Volume: 75
Issue: 3
Pages: 204-9
Publication
First Author: Maire CL
Year: 2014
Journal: Stem Cells
Title: Pten loss in Olig2 expressing neural progenitor cells and oligodendrocytes leads to interneuron dysplasia and leukodystrophy.
Volume: 32
Issue: 1
Pages: 313-26
Publication
First Author: Mateo JL
Year: 2015
Journal: Genome Res
Title: Characterization of the neural stem cell gene regulatory network identifies OLIG2 as a multifunctional regulator of self-renewal.
Volume: 25
Issue: 1
Pages: 41-56
Publication
First Author: Hafler BP
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Transcription factor Olig2 defines subpopulations of retinal progenitor cells biased toward specific cell fates.
Volume: 109
Issue: 20
Pages: 7882-7
Publication
First Author: Wedel M
Year: 2020
Journal: Nucleic Acids Res
Title: Transcription factor Tcf4 is the preferred heterodimerization partner for Olig2 in oligodendrocytes and required for differentiation.
Volume: 48
Issue: 9
Pages: 4839-4857
Publication
First Author: Takebayashi H
Year: 2000
Journal: Mech Dev
Title: Dynamic expression of basic helix-loop-helix Olig family members: implication of Olig2 in neuron and oligodendrocyte differentiation and identification of a new member, Olig3.
Volume: 99
Issue: 1-2
Pages: 143-8
Publication
First Author: Sun T
Year: 2003
Journal: J Neurosci
Title: Cross-repressive interaction of the Olig2 and Nkx2.2 transcription factors in developing neural tube associated with formation of a specific physical complex.
Volume: 23
Issue: 29
Pages: 9547-56
Publication      
First Author: Bizen N
Year: 2022
Journal: Cell Death Differ
Title: Ddx20, an Olig2 binding factor, governs the survival of neural and oligodendrocyte progenitor cells via proper Mdm2 splicing and p53 suppression.
Publication
First Author: Fu H
Year: 2002
Journal: Development
Title: Dual origin of spinal oligodendrocyte progenitors and evidence for the cooperative role of Olig2 and Nkx2.2 in the control of oligodendrocyte differentiation.
Volume: 129
Issue: 3
Pages: 681-93
Publication
First Author: Touahri Y
Year: 2012
Journal: J Neurosci
Title: Sulfatase 1 promotes the motor neuron-to-oligodendrocyte fate switch by activating Shh signaling in Olig2 progenitors of the embryonic ventral spinal cord.
Volume: 32
Issue: 50
Pages: 18018-34
Publication  
First Author: Del Águila Á
Year: 2022
Journal: Development
Title: Olig2 defines a subset of neural stem cells that produce specific olfactory bulb interneuron subtypes in the subventricular zone of adult mice.
Volume: 149
Issue: 5
GXD Expression
Probe: MGI:6194278
Assay Type: Immunohistochemistry
Annotation Date: 2018-08-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778721
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6194396
Age: embryonic day 12.5
Image: 5A
Note: Olig2 expression almost completely overlapped with Neurog1.
Specimen Label: 5A
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:6179817
Assay Type: RNA in situ
Annotation Date: 2020-09-22
Strength: Present
Sex: Male
Emaps: EMAPS:1754426
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:6456774
Age: embryonic day 18.5
Image: S13
Note: Olig2 is a marker for oligodendrocytes.
Specimen Label: S13
Detected: true
Specimen Num: 1
Publication
First Author: Ono K
Year: 2008
Journal: Dev Biol
Title: Regional- and temporal-dependent changes in the differentiation of Olig2 progenitors in the forebrain, and the impact on astrocyte development in the dorsal pallium.
Volume: 320
Issue: 2
Pages: 456-68
Publication
First Author: Bansal R
Year: 2003
Journal: Dev Neurosci
Title: Expression of FGF receptors 1, 2, 3 in the embryonic and postnatal mouse brain compared with Pdgfralpha, Olig2 and Plp/dm20: implications for oligodendrocyte development.
Volume: 25
Issue: 2-4
Pages: 83-95
GXD Expression    
Probe: MGI:6179817
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6190994
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Olig2
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6179817
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6190994
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Olig2
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6179817
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6190994
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Olig2
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:6179817
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6190994
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Olig2
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:6179817
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190994
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Olig2
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:6179817
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190994
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Olig2
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:6179817
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190994
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Olig2
Detected: true
Specimen Num: 7
GXD Expression
Probe: MGI:2157971
Assay Type: RNA in situ
Annotation Date: 2002-03-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757727
Pattern: Uniform
Stage: TS27
Assay Id: MGI:2176469
Age: postnatal day 1
Image: 5G
Note: Nkx2-2 and Olig2 expression domains overlap at this stage.
Specimen Label: 5G
Detected: true
Specimen Num: 11
GXD Expression
Probe: MGI:2157971
Assay Type: RNA in situ
Annotation Date: 2002-03-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757727
Pattern: Uniform
Stage: TS27
Assay Id: MGI:2176469
Age: postnatal day 1
Image: 5H
Note: Nkx2-2 and Olig2 expression domains overlap at this stage.
Specimen Label: 5H
Detected: true
Specimen Num: 12
GXD Expression
Probe: MGI:6194278
Assay Type: Immunohistochemistry
Annotation Date: 2018-08-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778721
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:6194396
Age: embryonic day 12.5
Image: 6A/B
Note: Olig2 expression overlapped with Neurod1 near the cerebellar ventricular zone.
Specimen Label: 6A/B
Detected: true
Specimen Num: 5
GXD Expression
Probe: MGI:6200636
Assay Type: Immunohistochemistry
Annotation Date: 2018-10-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1609217
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:6200651
Age: embryonic day 10.5
Image: 6p
Note: In the mutant, scattered Olig2 cells are displaced dorsally.
Specimen Label: 6p
Detected: true
Specimen Num: 3
GXD Expression
Probe: MGI:6200636
Assay Type: Immunohistochemistry
Annotation Date: 2018-10-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1609217
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:6200651
Age: embryonic day 10.5
Image: 6u
Note: In the mutant, scattered Olig2 cells are displaced dorsally.
Specimen Label: 6u
Detected: true
Specimen Num: 5
GXD Expression
Probe: MGI:6200636
Assay Type: Immunohistochemistry
Annotation Date: 2018-10-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1609217
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:6200651
Age: embryonic day 10.5
Image: 6q
Note: Knockout embryos show intermixing of Olig2 and Nkx2-2 progenitors.
Specimen Label: 6q
Detected: true
Specimen Num: 4
GXD Expression
Probe: MGI:6200636
Assay Type: Immunohistochemistry
Annotation Date: 2018-10-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1609217
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:6200651
Age: embryonic day 10.5
Image: 6v
Note: Knockout embryos show intermixing of Olig2 and Nkx2-2 progenitors.
Specimen Label: 6v
Detected: true
Specimen Num: 6
GXD Expression  
Probe: MGI:6509634
Assay Type: Immunohistochemistry
Annotation Date: 2021-03-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757721
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:6509957
Age: embryonic day 13.5
Note: Olig2 is a ventral neuronal precursor marker (pMN marker).
Specimen Label: not shown
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:6194277
Assay Type: Immunohistochemistry
Annotation Date: 2018-08-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778721
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:6194375
Age: embryonic day 12.5
Image: 6G,H
Note: Olig2 expression was distinct from that of Skor2, an early marker of Purkinje cells.
Specimen Label: 6G,H
Detected: true
Specimen Num: 7
GXD Expression
Probe: MGI:6194277
Assay Type: Immunohistochemistry
Annotation Date: 2018-08-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778721
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:6194291
Age: embryonic day 12.5
Image: 2E,F,G
Note: Some of the Olig2 immunopositive cells were also labeled with Mki67, a mitotic cell marker.
Specimen Label: 2E,F,G
Detected: true
Specimen Num: 8
GXD Expression
Probe: MGI:6194277
Assay Type: Immunohistochemistry
Annotation Date: 2018-08-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778721
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:6194375
Age: embryonic day 12.5
Image: 6D,E
Note: Olig2 expression was distinct from that of Skor2, an early marker of Purkinje cells.
Specimen Label: 6D,E
Detected: true
Specimen Num: 6
GXD Expression
Probe: MGI:6194277
Assay Type: Immunohistochemistry
Annotation Date: 2018-08-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778721
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:6194291
Age: embryonic day 12.5
Image: 2I,J,K
Note: Some of the Olig2 immunopositive cells were also labeled with BrdU, which labels cells undergoing DNA synthesis.
Specimen Label: 2I,J,K
Detected: true
Specimen Num: 9
GXD Expression
Probe: MGI:6194277
Assay Type: Immunohistochemistry
Annotation Date: 2018-08-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778721
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:6194375
Age: embryonic day 12.5
Image: 2A,B,C
Note: Some of the Olig2 immunopositive cells were also labeled with Ptf1a, a marker for GABAergic neuron progenitors.
Specimen Label: 2A,B,C
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:6444779
Assay Type: Immunohistochemistry
Annotation Date: 2020-07-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1707819
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:6444829
Age: embryonic day 11.5
Image: 3G
Note: Expression in ventral rhombomere 1 (r1) in oligodendrocyte progenitor cells in mantle zone in vicinity of Olig2 neuroepithelial (NE) domain.
Specimen Label: 3G
Detected: true
Specimen Num: 6
GXD Expression
Probe: MGI:5586691
Assay Type: Immunohistochemistry
Annotation Date: 2022-06-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3525328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7281526
Age: postnatal day 21
Image: 2K
Note: Olig2 is a marker of the entire oligodendrocyte lineage. Expression of Olig2 overlapped with beta-gal staining for Lztr1. However, there were many cells stained only with Olig2.
Specimen Label: 2K
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:6194277
Assay Type: Immunohistochemistry
Annotation Date: 2023-08-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1707420
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:7520313
Age: embryonic day 12.5
Image: 3B/C
Note: Expression was predominantly localized in the ventricular zone. Overlapping Ptf1a and Olig2 expression in GABAergic precursors was observed in the intermediary region of the ventricular zone.
Specimen Label: 3B/C
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:5751839
Assay Type: Immunohistochemistry
Annotation Date: 2016-03-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3747120
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:5752065
Age: embryonic day 12.5
Note: Expression was detected in nearly all ventricular zone cells in the medial ganglionic eminence and colocalized with cells expressing Ccnd2. In the subventricular zone, cells expressed either Olig2 or Ccnd2.
Specimen Label: S4K/L
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:5751839
Assay Type: Immunohistochemistry
Annotation Date: 2016-03-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3747122
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5752065
Age: embryonic day 14.5
Note: Expression was detected in nearly all ventricular zone cells in the medial ganglionic eminence and colocalized with cells expressing Ccnd2. In the subventricular zone, cells expressed either Olig2 or Ccnd2.
Specimen Label: S4M/O
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:6194277
Assay Type: Immunohistochemistry
Annotation Date: 2018-08-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778721
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:6194375
Age: embryonic day 12.5
Image: 3A,G
Note: Triple labeling indicated that some Olig2-positive cells express Ptf1a (marker for GABAergic neuron progenitors) and other Olig2-positive cells express Lhx1 and Lhx5 (which mark postmitotic GABAergic neurons). The results indicate that Olig2 is expressed in both mitotic and postmitotic cells.
Specimen Label: 3A,G
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:6194277
Assay Type: Immunohistochemistry
Annotation Date: 2018-08-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3527224
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:6194291
Age: embryonic day 16.5
Image: 1G/H
Note: Expression was detected in the interposed and lateral deep cerebellar nuclei. High magnification of double staining showed cells that were immunopositive for both Olig2 and Pou3f2, as well as other cells that were only Olig2-positive.
Specimen Label: 1G/H
Detected: true
Specimen Num: 6
Publication  
First Author: Paes de Faria J
Year: 2014
Journal: BMC Neurosci
Title: New Olig1 null mice confirm a non-essential role for Olig1 in oligodendrocyte development.
Volume: 15
Pages: 12
Allele
Name: transgene insertion JD97, Nathaniel Heintz
Allele Type: Transgenic
Attribute String: Reporter
Publication      
First Author: Garcia-Perez L B
Year: 2022
Journal: PhD Thesis - Imperial College London
Title: A quantitative analysis of tissue development: understanding the role of two mutually repressing transcription factors, Irx3 and Olig2, in the developing spinal cord.
Publication
First Author: Imayoshi I
Year: 2013
Journal: Science
Title: Oscillatory control of factors determining multipotency and fate in mouse neural progenitors.
Volume: 342
Issue: 6163
Pages: 1203-8
Publication
First Author: Usui N
Year: 2012
Journal: Development
Title: Role of motoneuron-derived neurotrophin 3 in survival and axonal projection of sensory neurons during neural circuit formation.
Volume: 139
Issue: 6
Pages: 1125-32
Publication
First Author: Wang F
Year: 2020
Journal: Nat Neurosci
Title: Myelin degeneration and diminished myelin renewal contribute to age-related deficits in memory.
Volume: 23
Issue: 4
Pages: 481-486
Publication
First Author: Zhou J
Year: 2017
Journal: Cell Rep
Title: A Sequentially Priming Phosphorylation Cascade Activates the Gliomagenic Transcription Factor Olig2.
Volume: 18
Issue: 13
Pages: 3167-3177
Publication
First Author: Zawadzka M
Year: 2010
Journal: Cell Stem Cell
Title: CNS-resident glial progenitor/stem cells produce Schwann cells as well as oligodendrocytes during repair of CNS demyelination.
Volume: 6
Issue: 6
Pages: 578-90
Publication
First Author: Grier MD
Year: 2017
Journal: PLoS One
Title: Loss of mTORC2 signaling in oligodendrocyte precursor cells delays myelination.
Volume: 12
Issue: 11
Pages: e0188417
Publication
First Author: Ligon KL
Year: 2007
Journal: Neuron
Title: Olig2-regulated lineage-restricted pathway controls replication competence in neural stem cells and malignant glioma.
Volume: 53
Issue: 4
Pages: 503-17
Publication  
First Author: Liu W
Year: 2015
Journal: Neurobiol Dis
Title: Disruption of neurogenesis and cortical development in transgenic mice misexpressing Olig2, a gene in the Down syndrome critical region.
Volume: 77
Pages: 106-16
Publication
First Author: Dimou L
Year: 2008
Journal: J Neurosci
Title: Progeny of Olig2-expressing progenitors in the gray and white matter of the adult mouse cerebral cortex.
Volume: 28
Issue: 41
Pages: 10434-42
Publication
First Author: Tatsumi K
Year: 2021
Journal: Mol Brain
Title: Olig2-astrocytes express neutral amino acid transporter SLC7A10 (Asc-1) in the adult brain.
Volume: 14
Issue: 1
Pages: 163
Publication
First Author: Zhao JW
Year: 2009
Journal: Eur J Neurosci
Title: Astrocytes and oligodendrocytes can be generated from NG2+ progenitors after acute brain injury: intracellular localization of oligodendrocyte transcription factor 2 is associated with their fate choice.
Volume: 29
Issue: 9
Pages: 1853-69
Publication
First Author: Yue T
Year: 2006
Journal: J Neurosci
Title: A critical role for dorsal progenitors in cortical myelination.
Volume: 26
Issue: 4
Pages: 1275-80
Publication
First Author: Ligon KL
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Development of NG2 neural progenitor cells requires Olig gene function.
Volume: 103
Issue: 20
Pages: 7853-8
Publication      
First Author: Elbaz B
Year: 2023
Journal: Neuron
Title: The bone transcription factor Osterix controls extracellular matrix- and node of Ranvier-related gene expression in oligodendrocytes.
Publication
First Author: Boshans LL
Year: 2021
Journal: Sci Rep
Title: Direct reprogramming of oligodendrocyte precursor cells into GABAergic inhibitory neurons by a single homeodomain transcription factor Dlx2.
Volume: 11
Issue: 1
Pages: 3552
Publication    
First Author: Ronzano R
Year: 2022
Journal: Elife
Title: Spinal premotor interneurons controlling antagonistic muscles are spatially intermingled.
Volume: 11
Publication
First Author: Kunkel TJ
Year: 2023
Journal: Nat Commun
Title: The cholesterol transporter NPC1 is essential for epigenetic regulation and maturation of oligodendrocyte lineage cells.
Volume: 14
Issue: 1
Pages: 3964
Publication
First Author: Lu QR
Year: 2002
Journal: Cell
Title: Common developmental requirement for Olig function indicates a motor neuron/oligodendrocyte connection.
Volume: 109
Issue: 1
Pages: 75-86
Publication
First Author: Wicher G
Year: 2008
Journal: Neuroreport
Title: Megalin deficiency induces critical changes in mouse spinal cord development.
Volume: 19
Issue: 5
Pages: 559-63