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Search results 101 to 196 out of 196 for Oma1

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0.031s
Type Details Score
GXD Expression  
Probe: MGI:1627779
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1752323
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4826970
Age: embryonic day 14.5
Image: euxassay_002976_14
Specimen Label: euxassay_002976_14
Detected: true
Specimen Num: 7
GXD Expression  
Probe: MGI:1627779
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826970
Age: embryonic day 14.5
Image: euxassay_002976_14
Specimen Label: euxassay_002976_14
Detected: true
Specimen Num: 7
GXD Expression  
Probe: MGI:1627779
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1752323
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4826970
Age: embryonic day 14.5
Image: euxassay_002976_15
Specimen Label: euxassay_002976_15
Detected: true
Specimen Num: 8
GXD Expression  
Probe: MGI:1627779
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826970
Age: embryonic day 14.5
Image: euxassay_002976_15
Specimen Label: euxassay_002976_15
Detected: true
Specimen Num: 8
GXD Expression  
Probe: MGI:1627779
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1752323
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4826970
Age: embryonic day 14.5
Image: euxassay_002976_16
Specimen Label: euxassay_002976_16
Detected: true
Specimen Num: 9
GXD Expression  
Probe: MGI:1627779
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826970
Age: embryonic day 14.5
Image: euxassay_002976_16
Specimen Label: euxassay_002976_16
Detected: true
Specimen Num: 9
GXD Expression  
Probe: MGI:1627779
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1752323
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4826970
Age: embryonic day 14.5
Image: euxassay_002976_17
Specimen Label: euxassay_002976_17
Detected: true
Specimen Num: 10
GXD Expression  
Probe: MGI:1627779
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826970
Age: embryonic day 14.5
Image: euxassay_002976_17
Specimen Label: euxassay_002976_17
Detected: true
Specimen Num: 10
GXD Expression  
Probe: MGI:1627779
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826970
Age: embryonic day 14.5
Image: euxassay_002976_18
Specimen Label: euxassay_002976_18
Detected: true
Specimen Num: 11
GXD Expression  
Probe: MGI:1627779
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1775523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826970
Age: embryonic day 14.5
Image: euxassay_002976_18
Specimen Label: euxassay_002976_18
Detected: true
Specimen Num: 11
GXD Expression  
Probe: MGI:1627779
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826970
Age: embryonic day 14.5
Image: euxassay_002976_19
Specimen Label: euxassay_002976_19
Detected: true
Specimen Num: 12
GXD Expression  
Probe: MGI:1627779
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1775523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826970
Age: embryonic day 14.5
Image: euxassay_002976_19
Specimen Label: euxassay_002976_19
Detected: true
Specimen Num: 12
GXD Expression  
Probe: MGI:1627779
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826970
Age: embryonic day 14.5
Image: euxassay_002976_20
Specimen Label: euxassay_002976_20
Detected: true
Specimen Num: 13
GXD Expression  
Probe: MGI:1627779
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1775523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826970
Age: embryonic day 14.5
Image: euxassay_002976_20
Specimen Label: euxassay_002976_20
Detected: true
Specimen Num: 13
GXD Expression  
Probe: MGI:1627779
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1775523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826970
Age: embryonic day 14.5
Image: euxassay_002976_21
Specimen Label: euxassay_002976_21
Detected: true
Specimen Num: 14
GXD Expression    
Probe: MGI:1627779
Assay Type: RNA in situ
Annotation Date: 2024-01-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3270322
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7575913
Age: embryonic day 14.5
Specimen Label: Supplementary table 2
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:1627779
Assay Type: RNA in situ
Annotation Date: 2024-01-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3271222
Pattern: Non-Uniform
Stage: TS22
Assay Id: MGI:7575913
Age: embryonic day 14.5
Note: Rostral expression was greater than caudal.
Specimen Label: Supplementary table 2
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:1627779
Assay Type: RNA in situ
Annotation Date: 2024-01-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3271122
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7575913
Age: embryonic day 14.5
Specimen Label: Supplementary table 2
Detected: true
Specimen Num: 1
Publication
First Author: Wai T
Year: 2015
Journal: Science
Title: Imbalanced OPA1 processing and mitochondrial fragmentation cause heart failure in mice.
Volume: 350
Issue: 6265
Pages: aad0116
Publication
First Author: Kondadi AK
Year: 2014
Journal: EMBO J
Title: Loss of the m-AAA protease subunit AFG₃L₂ causes mitochondrial transport defects and tau hyperphosphorylation.
Volume: 33
Issue: 9
Pages: 1011-26
Publication
First Author: Wani GA
Year: 2022
Journal: Cell Rep
Title: Metabolic control of adult neural stem cell self-renewal by the mitochondrial protease YME1L.
Volume: 38
Issue: 7
Pages: 110370
Publication
First Author: Yang Q
Year: 2023
Journal: FASEB J
Title: Loss of UCP2 causes mitochondrial fragmentation by OMA1-dependent proteolytic processing of OPA1 in podocytes.
Volume: 37
Issue: 11
Pages: e23265
Publication
First Author: König T
Year: 2016
Journal: Mol Cell
Title: The m-AAA Protease Associated with Neurodegeneration Limits MCU Activity in Mitochondria.
Volume: 64
Issue: 1
Pages: 148-162
Publication
First Author: Ehses S
Year: 2009
Journal: J Cell Biol
Title: Regulation of OPA1 processing and mitochondrial fusion by m-AAA protease isoenzymes and OMA1.
Volume: 187
Issue: 7
Pages: 1023-36
Publication
First Author: Nicolás-Ávila JA
Year: 2020
Journal: Cell
Title: A Network of Macrophages Supports Mitochondrial Homeostasis in the Heart.
Volume: 183
Issue: 1
Pages: 94-109.e23
Publication
First Author: Bar I
Year: 2003
Journal: J Biol Chem
Title: The gene encoding disabled-1 (DAB1), the intracellular adaptor of the Reelin pathway, reveals unusual complexity in human and mouse.
Volume: 278
Issue: 8
Pages: 5802-12
Publication
First Author: Chen B
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: Fezl regulates the differentiation and axon targeting of layer 5 subcortical projection neurons in cerebral cortex.
Volume: 102
Issue: 47
Pages: 17184-9
Publication    
First Author: Li J
Year: 2018
Journal: Database (Oxford)
Title: CITGeneDB: a comprehensive database of human and mouse genes enhancing or suppressing cold-induced thermogenesis validated by perturbation experiments in mice.
Volume: 2018
Publication
First Author: Pagliarini DJ
Year: 2008
Journal: Cell
Title: A mitochondrial protein compendium elucidates complex I disease biology.
Volume: 134
Issue: 1
Pages: 112-23
Publication      
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
Publication      
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
Publication  
First Author: Bedogni F
Year: 2021
Journal: Front Mol Neurosci
Title: Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development.
Volume: 14
Pages: 686034
Publication
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication        
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
Publication        
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
UniProt Feature
Begin: 141
Description: Cleavage; by OMA1
Type: site
End: 142
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: frog, African clawed
Allele    
Name: OMA1 zinc metallopeptidase; wild type
Allele
Name: OMA1 zinc metallopeptidase; endonuclease-mediated mutation 1, Helmholtz Zentrum Muenchen GmbH
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
Allele
Name: OMA1 zinc metallopeptidase; targeted mutation 1a, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Conditional ready, Null/knockout, Reporter
Allele
Name: OMA1 zinc metallopeptidase; targeted mutation 1, Thomas Langer
Allele Type: Targeted
Attribute String: Conditional ready
Allele
Name: OMA1 zinc metallopeptidase; targeted mutation 1, Carlos Lopez-Otin
Allele Type: Targeted
Attribute String: Null/knockout
Allele
Name: OMA1 zinc metallopeptidase; targeted mutation 2e, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
Allele
Name: OMA1 zinc metallopeptidase; targeted mutation 1.1, Thomas Langer
Allele Type: Targeted
Attribute String: Null/knockout
Allele
Name: OMA1 zinc metallopeptidase; targeted mutation 1e, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
Allele
Name: OMA1 zinc metallopeptidase; targeted mutation 3e, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
Allele
Name: OMA1 zinc metallopeptidase; targeted mutation 2a, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Conditional ready, Null/knockout, Reporter
Publication
First Author: Anderson CJ
Year: 2020
Journal: Cell Death Differ
Title: Prohibitin levels regulate OMA1 activity and turnover in neurons.
Volume: 27
Issue: 6
Pages: 1896-1906
Strain
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
Strain
Attribute String: coisogenic, targeted mutation
Genotype
Symbol: Oma1/Oma1
Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6NCr
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Oma1/Oma1
Background: C57BL/6N-Oma1/Ieg
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Chchd10/Chchd10 Oma1/Oma1
Background: involves: 129S6/SvEvTac * C57BL/6J * C57BL/6NCrl
Zygosity: cx
Has Mutant Allele: true
Allele
Name: transgene insertion LU178, GENSAT Project at Rockefeller University
Allele Type: Transgenic
Attribute String: Reporter
Genotype
Symbol: Oma1/Oma1 Yme1l1/Yme1l1 Tg(Myh6-cre)2182Mds/?
Background: involves: C57BL/6 * C57BL/6NCrl * FVB/N
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Oma1/Oma1 Yme1l1/Yme1l1 Tg(Ckmm-cre)5Khn/?
Background: involves: C57BL/6 * C57BL/6NCrl * FVB
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Chchd10/Chchd10 Oma1/Oma1<+>
Background: involves: 129S6/SvEvTac * C57BL/6J * C57BL/6NCrl
Zygosity: cx
Has Mutant Allele: true
Strain
Attribute String: mutant stock, transgenic
Publication
First Author: Frezza C
Year: 2006
Journal: Cell
Title: OPA1 controls apoptotic cristae remodeling independently from mitochondrial fusion.
Volume: 126
Issue: 1
Pages: 177-89
Protein Domain
Type: Family
Description: Opa1 is a dynamin-like guanosine triphosphatase required for mitochondrial fusion and regulation of apoptosis. Its activity is controlled by proteolytic cleavage. Stress conditions that cause loss of mitochondrial membrane potential can induce the cleavage of Opa1 at S1 position by OMA1 (an ATP-independent peptidase), and this triggers mitochondrial fragmentation []. It is also involved in mitochondrial cristae remodeling during apoptosis [].
Publication  
First Author: Consolato F
Year: 2018
Journal: J Cell Sci
Title: m-AAA and i-AAA complexes coordinate to regulate OMA1, the stress-activated supervisor of mitochondrial dynamics.
Volume: 131
Issue: 7
Publication
First Author: Wang R
Year: 2021
Journal: Mol Biol Cell
Title: Identification of new OPA1 cleavage site reveals that short isoforms regulate mitochondrial fusion.
Volume: 32
Issue: 2
Pages: 157-168
Publication
First Author: Zhou Z
Year: 2018
Journal: J Biol Chem
Title: Estrogen receptor α protects pancreatic β-cells from apoptosis by preserving mitochondrial function and suppressing endoplasmic reticulum stress.
Volume: 293
Issue: 13
Pages: 4735-4751
Publication
First Author: Sood A
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: A Mitofusin-2-dependent inactivating cleavage of Opa1 links changes in mitochondria cristae and ER contacts in the postprandial liver.
Volume: 111
Issue: 45
Pages: 16017-22
Protein
Organism: Mus musculus/domesticus
Length: 296  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 960  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 953  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 692  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 978  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 567  
Fragment?: false
Publication      
First Author: The Gene Expression Nervous System Atlas (GENSAT) Project, The Rockefeller University (New York, NY)
Year: 2005
Journal: Database Download
Title: MGI download of GENSAT transgene data