|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 101 to 190 out of 190 for Snrnp70

<< First    < Previous  |  Next >    Last >>
0.025s

Categories

Hits by Pathway

Hits by Strain

Hits by Category

Type Details Score
GXD Expression
GXD Expression
   
Probe: MGI:4846069
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Ambiguous
Sex: Male
Emaps: EMAPS:1736820
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:5540880
Age: embryonic day 12.5
Image: GUDMAP:8322
Specimen Label: GUDMAP:8322
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:4846069
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Ambiguous
Sex: Female
Emaps: EMAPS:1736820
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:5540880
Age: embryonic day 12.5
Image: GUDMAP:8324
Specimen Label: GUDMAP:8324
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4846069
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:2890920
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:5540880
Age: embryonic day 12.5
Image: GUDMAP:8323
Specimen Label: GUDMAP:8323
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:3615980
Assay Type: RNA in situ
Annotation Date: 2006-03-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:3617612
Age: embryonic day 13.5
Image: E13.5
Note: Expression was detected in precortical tissue.
Specimen Label: E13.5
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3615980
Assay Type: RNA in situ
Annotation Date: 2006-03-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754427
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:3617612
Age: postnatal day 0
Image: P0
Specimen Label: P0
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4846069
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:1796820
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:5540880
Age: embryonic day 12.5
Image: GUDMAP:8321
Specimen Label: GUDMAP:8321
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3615980
Assay Type: RNA in situ
Annotation Date: 2006-03-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284527
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:3617612
Age: postnatal day 0
Image: P0
Specimen Label: P0
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:4846069
Assay Type: RNA in situ
Annotation Date: 2010-12-30
Strength: Present
Sex: Male
Emaps: EMAPS:2909820
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:4849817
Age: embryonic day 12.5
Specimen Label: GUDMAP:8321
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4846069
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:2909820
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:5540880
Age: embryonic day 12.5
Image: GUDMAP:8321
Specimen Label: GUDMAP:8321
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:4846069
Assay Type: RNA in situ
Annotation Date: 2010-12-30
Strength: Absent
Sex: Male
Emaps: EMAPS:2913820
Stage: TS20
Assay Id: MGI:4849817
Age: embryonic day 12.5
Note: No expression is found at the gonad-mesonephros border on the mesonephric side.
Specimen Label: GUDMAP:8321
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4846069
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:2913820
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:5540880
Age: embryonic day 12.5
Image: GUDMAP:8321
Specimen Label: GUDMAP:8321
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4846069
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Ambiguous
Sex: Female
Emaps: EMAPS:2891420
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:5540880
Age: embryonic day 12.5
Image: GUDMAP:8323
Note: possible signal in dorsal mesonephros
Specimen Label: GUDMAP:8323
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4846069
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:1797220
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:5540880
Age: embryonic day 12.5
Image: GUDMAP:8321
Specimen Label: GUDMAP:8321
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:4846069
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2891920
Stage: TS20
Assay Id: MGI:5540880
Age: embryonic day 12.5
Image: GUDMAP:8323
Specimen Label: GUDMAP:8323
Detected: false
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4846069
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Ambiguous
Sex: Male
Emaps: EMAPS:2914320
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:5540880
Age: embryonic day 12.5
Image: GUDMAP:8321
Note: possible signal in dorsal mesonephros
Specimen Label: GUDMAP:8321
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3615980
Assay Type: RNA in situ
Annotation Date: 2006-03-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1679727
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:3617612
Age: postnatal day 0
Image: P0
Specimen Label: P0
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3615980
Assay Type: RNA in situ
Annotation Date: 2006-03-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754027
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:3617612
Age: postnatal day 0
Image: P0
Specimen Label: P0
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3615980
Assay Type: RNA in situ
Annotation Date: 2006-03-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3280927
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:3617612
Age: postnatal day 0
Image: P0
Specimen Label: P0
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:4846069
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Ambiguous
Sex: Male
Emaps: EMAPS:1797320
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:5540880
Age: embryonic day 12.5
Image: GUDMAP:8321
Specimen Label: GUDMAP:8321
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:4846069
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2892420
Stage: TS20
Assay Id: MGI:5540880
Age: embryonic day 12.5
Image: GUDMAP:8323
Specimen Label: GUDMAP:8323
Detected: false
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3615980
Assay Type: RNA in situ
Annotation Date: 2006-03-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3267921
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:3617612
Age: embryonic day 13.5
Image: E13.5
Specimen Label: E13.5
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3615980
Assay Type: RNA in situ
Annotation Date: 2006-03-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757721
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:3617612
Age: embryonic day 13.5
Image: E13.5
Specimen Label: E13.5
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3615980
Assay Type: RNA in situ
Annotation Date: 2006-03-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757727
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:3617612
Age: postnatal day 0
Image: P0
Specimen Label: P0
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4846069
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:1796220
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:5540880
Age: embryonic day 12.5
Image: GUDMAP:8323
Specimen Label: GUDMAP:8323
Detected: true
Specimen Num: 3
•
•
•
•
•
Publication
17656373 | J:129888
First Author: Howell VM
Year: 2007
Journal: Hum Mol Genet
Title: Evidence for a direct role of the disease modifier SCNM1 in splicing.
Volume: 16
Issue: 20
Pages: 2506-16
•
•
•
•
•
Publication
29701768 | J:263783
First Author: Donadon I
Year: 2018
Journal: Hum Mol Genet
Title: Exon-specific U1 snRNAs improve ELP1 exon 20 definition and rescue ELP1 protein expression in a familial dysautonomia mouse model.
Volume: 27
Issue: 14
Pages: 2466-2476
•
•
•
•
•
Publication
8037837 | J:17842
First Author: Pelsue S
Year: 1994
Journal: J Autoimmun
Title: Gene usage by an anti-U1 snRNP 70K monoclonal autoantibody derived from a lupus-prone mouse.
Volume: 7
Issue: 2
Pages: 165-77
•
•
•
•
•
Publication
18523312 | J:137131
First Author: Greidinger EL
Year: 2008
Journal: J Immunol
Title: CD4+ T cells target epitopes residing within the RNA-binding domain of the U1-70-kDa small nuclear ribonucleoprotein autoantigen and have restricted TCR diversity in an HLA-DR4-transgenic murine model of mixed connective tissue disease.
Volume: 180
Issue: 12
Pages: 8444-54
•
•
•
•
•
Publication
19196664 | J:148121
First Author: Yamamoto ML
Year: 2009
Journal: Blood
Title: Alternative pre-mRNA splicing switches modulate gene expression in late erythropoiesis.
Volume: 113
Issue: 14
Pages: 3363-70
•
•
•
•
•
Publication
9315092 | J:43082
First Author: Oda T
Year: 1997
Journal: Oncogene
Title: Identification and characterization of two novel SH2 domain-containing proteins from a yeast two hybrid screen with the ABL tyrosine kinase.
Volume: 15
Issue: 11
Pages: 1255-62
•
•
•
•
•
Publication
18559850 | J:137212
First Author: Pessa HK
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Minor spliceosome components are predominantly localized in the nucleus.
Volume: 105
Issue: 25
Pages: 8655-60
•
•
•
•
•
Publication
21283520 | J:301700
First Author: Cao H
Year: 2011
Journal: PLoS One
Title: Temporal and tissue specific regulation of RP-associated splicing factor genes PRPF3, PRPF31 and PRPC8--implications in the pathogenesis of RP.
Volume: 6
Issue: 1
Pages: e15860
•
•
•
•
•
Publication
23636947 | J:204486
First Author: Zheng S
Year: 2013
Journal: Genome Res
Title: A broadly applicable high-throughput screening strategy identifies new regulators of Dlg4 (Psd-95) alternative splicing.
Volume: 23
Issue: 6
Pages: 998-1007
•
•
•
•
•
Publication
35739118 | J:326362
First Author: Feng S
Year: 2022
Journal: Nat Commun
Title: hnRNPH1 recruits PTBP2 and SRSF3 to modulate alternative splicing in germ cells.
Volume: 13
Issue: 1
Pages: 3588
•
•
•
•
•
Publication
1981054 | J:10993
First Author: Saunders AM
Year: 1990
Journal: Genomics
Title: A molecular genetic linkage map of mouse chromosome 7.
Volume: 8
Issue: 3
Pages: 525-35
•
•
•
•
•
Publication
8812484 | J:34617
First Author: Stubbs L
Year: 1996
Journal: Genomics
Title: Detailed comparative map of human chromosome 19q and related regions of the mouse genome.
Volume: 35
Issue: 3
Pages: 499-508
•
•
•
•
•
Publication
19334288 | J:148410
First Author: Combes AN
Year: 2009
Journal: Dev Dyn
Title: Three-dimensional visualization of testis cord morphogenesis, a novel tubulogenic mechanism in development.
Volume: 238
Issue: 5
Pages: 1033-41
•
•
•
•
•
Publication
16033648 | J:103446
 
First Author: McKee AE
Year: 2005
Journal: BMC Dev Biol
Title: A genome-wide in situ hybridization map of RNA-binding proteins reveals anatomically restricted expression in the developing mouse brain.
Volume: 5
Pages: 14
•
•
•
•
•
Publication
15741177 | J:126097
First Author: Cobellis G
Year: 2005
Journal: Nucleic Acids Res
Title: Tagging genes with cassette-exchange sites.
Volume: 33
Issue: 4
Pages: e44
•
•
•
•
•
Publication
- | J:77000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: MGC Data curation in Mouse Genome Informatics
•
•
•
•
•
Publication
- | J:345476
       
First Author: Haiming Tang, Dustin Ebert, Matthias Blum, Robert Finn, Paul Thomas
Year: 2023
Title: TreeGrafter-generated GO annotations
•
•
•
•
•
Publication
- | J:80001
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: FANTOM2 Data Curation in Mouse Genome Informatics
•
•
•
•
•
Publication
- | J:81858
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: Data Curation Using Mouse Genome Assembly
•
•
•
•
•
Publication
12904583 | J:85162
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
•
•
•
•
•
Publication
17967808 | J:152068
First Author: Friedel RH
Year: 2007
Journal: Brief Funct Genomic Proteomic
Title: EUCOMM--the European conditional mouse mutagenesis program.
Volume: 6
Issue: 3
Pages: 180-5
•
•
•
•
•
Publication
- | J:265051
     
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
•
•
•
•
•
Publication
12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
•
•
•
•
•
Publication
- | J:57656
     
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
•
•
•
•
•
Publication
- | J:171409
     
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
•
•
•
•
•
Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
•
•
•
•
•
Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
•
•
•
•
•
Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
•
•
•
•
•
Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
•
•
•
•
•
Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
•
•
•
•
•
Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
•
•
•
•
•
Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
•
•
•
•
•
Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
•
•
•
•
•
Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
•
•
•
•
•
Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
•
•
•
•
•
Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
•
•
•
•
•
Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
•
•
•
•
•
Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
•
•
•
•
•
Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
•
•
•
•
•
Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
•
•
•
•
•
Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
•
•
•
•
•
Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
•
•
•
•
•
Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
•
•
•
•
•
Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
•
•
•
•
•
Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
•
•
•
•
•
Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
•
•
•
•
•
Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
•
•
•
•
•
Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
•
•
•
•
•
Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
•
•
•
•
•
Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
•
•
•
•
•
Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
•
•
•
•
•
Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
•
•
•
•
•
Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
•
•
•
•
•
Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
•
•
•
•
•
Protein
Q62376
Organism: Mus musculus/domesticus
Length: 448  
Fragment?: false
•
•
•
•
•
Protein
Q62376-2
Organism: Mus musculus/domesticus
Length: 166  
Fragment?: false
•
•
•
•
•
Publication
21536904 | -
First Author: Cho S
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Interaction between the RNA binding domains of Ser-Arg splicing factor 1 and U1-70K snRNP protein determines early spliceosome assembly.
Volume: 108
Issue: 20
Pages: 8233-8
•
•
•
•
•
Publication
15611175 | -
First Author: Salz HK
Year: 2004
Journal: Genetics
Title: The Drosophila U1-70K protein is required for viability, but its arginine-rich domain is dispensable.
Volume: 168
Issue: 4
Pages: 2059-65
•
•
•
•
•
Publication
9685421 | -
First Author: Cao W
Year: 1998
Journal: J Biol Chem
Title: A serine/arginine-rich domain in the human U1 70k protein is necessary and sufficient for ASF/SF2 binding.
Volume: 273
Issue: 32
Pages: 20629-35
•
•
•
•
•
Publication
3028775 | -
First Author: Theissen H
Year: 1986
Journal: EMBO J
Title: Cloning of the human cDNA for the U1 RNA-associated 70K protein.
Volume: 5
Issue: 12
Pages: 3209-17
•
•
•
•
•
Publication
20519584 | -
First Author: Spiluttini B
Year: 2010
Journal: J Cell Sci
Title: Splicing-independent recruitment of U1 snRNP to a transcription unit in living cells.
Volume: 123
Issue: Pt 12
Pages: 2085-93
•
•
•
•
•
Protein Domain
IPR034143 | snRNP70_RRM
Type: Domain
Description: This entry represents the RNA recognition motif (RRM) of snRNP70 (also known as U1-70K), a key component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome []. U1-70K plays an essential role in targeting the U1 snRNP to the 5' splice site through protein-protein interactions with regulatory RNA-binding splicing factors, such as the RS protein ASF/SF2. It can also specifically bind to stem-loop I of the U1 small nuclear RNA (U1 snRNA) contained in the U1 snRNP complex. It also mediates the binding of U1C, another U1-specific protein, to the U1 snRNP complex [].U1-70K contains a conserved RNA recognition motif (RRM), followed by an adjacent glycine-rich region at the N-terminal half, and two serine/arginine-rich (SR) domains at the C-terminal half. The RRM is responsible for the binding of stem-loop I of U1 snRNA molecule. Additionally, the most prominent immunodominant region that can be recognized by auto-antibodies from autoimmune patients may be located within the RRM. The SR domains are involved in protein-protein interaction with SR proteins that mediate 5' splice site recognition []. For instance, the first SR domain is necessary and sufficient for ASF/SF2 binding [, ].Proteins containing this domain also includes Drosophila U1-70K that is an essential splicing factor required for viability in flies, but its SR domain is dispensable [].
•
•
•
•
•
Publication
19325628 | -
First Author: Pomeranz Krummel DA
Year: 2009
Journal: Nature
Title: Crystal structure of human spliceosomal U1 snRNP at 5.5 A resolution.
Volume: 458
Issue: 7237
Pages: 475-80
•
•
•
•
•
Protein
A2RS68
Organism: Mus musculus/domesticus
Length: 448  
Fragment?: false
•
•
•
•
•
Protein
Q9CR32
Organism: Mus musculus/domesticus
Length: 248  
Fragment?: true
•
•
•
•
•
Publication
15489334 | -
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom