| Type |
Details |
Score |
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2009 |
| Journal: |
Database Download |
| Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
| Year: |
2010 |
| Journal: |
Database Download |
| Title: |
Consensus CDS project |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Group |
| Year: |
2003 |
| Journal: |
Database Procedure |
| Title: |
Automatic Encodes (AutoE) Reference |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bairoch A |
| Year: |
1999 |
| Journal: |
Database Release |
| Title: |
SWISS-PROT Annotated protein sequence database |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2005 |
|
| Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics |
| Year: |
2010 |
| Journal: |
Database Release |
| Title: |
Protein Ontology Association Load. |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2005 |
|
| Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2009 |
| Journal: |
Database Download |
| Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
|
|
|
|
•
•
•
•
•
|
| Allele |
| Name: |
terminal nucleotidyltransferase 5C; endonuclease-mediated mutation 2, Shanghai Model Organisms Center |
| Allele Type: |
Endonuclease-mediated |
| Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
coisogenic, endonuclease-mediated mutation, mutant strain |
|
•
•
•
•
•
|
| Allele |
| Name: |
terminal nucleotidyltransferase 5C; endonuclease-mediated mutation 1, Shanghai Model Organisms Center |
| Allele Type: |
Endonuclease-mediated |
| Attribute String: |
Conditional ready, No functional change |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
391
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
447
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
427
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
82
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
428
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
390
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Barragán I |
| Year: |
2008 |
| Journal: |
Ann Hum Genet |
| Title: |
Genetic analysis of FAM46A in Spanish families with autosomal recessive retinitis pigmentosa: characterisation of novel VNTRs. |
| Volume: |
72 |
| Issue: |
Pt 1 |
| Pages: |
26-34 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kuchta K |
| Year: |
2016 |
| Journal: |
Nucleic Acids Res |
| Title: |
FAM46 proteins are novel eukaryotic non-canonical poly(A) polymerases. |
| Volume: |
44 |
| Issue: |
8 |
| Pages: |
3534-48 |
|
•
•
•
•
•
|
| Protein Domain |
| Type: |
Family |
| Description: |
This entry includes terminal nucleotidyltransferase 5A/B/C/D (TENT5A/B/C/D). In general, they contain a NTase (nucleotidyltransferase) domain, some members possess additional C-terminal PAP/OAS1 substrate binding domain []. They are active non-canonical poly(A) polymerases, which modify cytosolic and/or nuclear RNA 3' ends []. They have different functions in many tissues at various stages of development.Human TENT5A is a SMAD signalling pathway related protein, where SMADs are intercellular effectors of transforming growth factor-beta (TGF-beta) []. The TENT5C gene is one of the most frequently mutated genes in multiple myeloma. TENT5C acts as an onco-suppressor in multiple myeloma []. TENT5C also seems to enhance replication of some viruses, including yellow fever virus, in response to type I interferon []. |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Brouze M |
| Year: |
2024 |
| Journal: |
Nat Commun |
| Title: |
TENT5-mediated polyadenylation of mRNAs encoding secreted proteins is essential for gametogenesis in mice. |
| Volume: |
15 |
| Issue: |
1 |
| Pages: |
5331 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kuchta K |
| Year: |
2009 |
| Journal: |
Nucleic Acids Res |
| Title: |
Comprehensive classification of nucleotidyltransferase fold proteins: identification of novel families and their representatives in human. |
| Volume: |
37 |
| Issue: |
22 |
| Pages: |
7701-14 |
|
•
•
•
•
•
|