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Search results 101 to 193 out of 193 for Tlr1

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Type Details Score
Publication
16886064 | J:113110
First Author: Chen CJ
Year: 2006
Journal: J Clin Invest
Title: MyD88-dependent IL-1 receptor signaling is essential for gouty inflammation stimulated by monosodium urate crystals.
Volume: 116
Issue: 8
Pages: 2262-71
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Publication
17339472 | J:144277
First Author: Alugupalli KR
Year: 2007
Journal: J Immunol
Title: MyD88- and Bruton's tyrosine kinase-mediated signals are essential for T cell-independent pathogen-specific IgM responses.
Volume: 178
Issue: 6
Pages: 3740-9
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Publication
34206257 | J:308973
 
First Author: Gao Y
Year: 2021
Journal: Int J Mol Sci
Title: YAP/TEAD1 Complex Is a Default Repressor of Cardiac Toll-Like Receptor Genes.
Volume: 22
Issue: 13
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Publication
22666391 | J:187296
First Author: Kaul D
Year: 2012
Journal: PLoS One
Title: Expression of Toll-like receptors in the developing brain.
Volume: 7
Issue: 5
Pages: e37767
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Publication
25681338 | J:274041
First Author: Onishi M
Year: 2015
Journal: J Immunol
Title: Hydroxypropyl-β-cyclodextrin spikes local inflammation that induces Th2 cell and T follicular helper cell responses to the coadministered antigen.
Volume: 194
Issue: 6
Pages: 2673-82
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Publication
31729371 | J:281617
First Author: Balounová J
Year: 2019
Journal: Nat Commun
Title: Toll-like receptor 2 expression on c-kit+ cells tracks the emergence of embryonic definitive hematopoietic progenitors.
Volume: 10
Issue: 1
Pages: 5176
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Publication
27022143 | J:233073
First Author: de Valle E
Year: 2016
Journal: J Exp Med
Title: NFκB1 is essential to prevent the development of multiorgan autoimmunity by limiting IL-6 production in follicular B cells.
Volume: 213
Issue: 4
Pages: 621-41
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Publication
34395439 | J:310855
 
First Author: Yiu JHC
Year: 2021
Journal: Front Cell Dev Biol
Title: TLR5 Supports Development of Placental Labyrinthine Zone in Mice.
Volume: 9
Pages: 711253
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Publication
27318131 | J:239041
 
First Author: Norden DM
Year: 2016
Journal: Neurobiol Aging
Title: Insensitivity of astrocytes to interleukin 10 signaling following peripheral immune challenge results in prolonged microglial activation in the aged brain.
Volume: 44
Pages: 22-41
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Publication
27480124 | J:237787
First Author: Liu X
Year: 2016
Journal: BMC Immunol
Title: Decreased expression levels of Ifi genes is associated to the increased resistance to spontaneous arthritis disease in mice deficiency of IL-1RA.
Volume: 17
Issue: 1
Pages: 25
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:72245
       
First Author: GOA curators, MGI curators
Year: 2001
Title: Gene Ontology annotation based on Enzyme Commission mapping
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Publication
- | J:73065
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Strain
MGI:4839600 | B6.129P2-Tlr1<tm1Aki>/Obs
Attribute String: targeted mutation, mutant strain, congenic
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GO Term
GO:0034130 | toll-like receptor 1 signaling pathway
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Allele
Tlr1<em1Smoc> | MGI:7292804
Name: toll-like receptor 1; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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GO Term
GO:0034131 | regulation of toll-like receptor 1 signaling pathway
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GO Term
GO:0034132 | negative regulation of toll-like receptor 1 signaling pathway
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GO Term
GO:0034133 | positive regulation of toll-like receptor 1 signaling pathway
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Strain
MGI:6355258 | C57BL/6J-Tlr1<em1Smoc>/Smoc
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Publication
11123271 | -
First Author: Hajjar AM
Year: 2001
Journal: J Immunol
Title: Cutting edge: functional interactions between toll-like receptor (TLR) 2 and TLR1 or TLR6 in response to phenol-soluble modulin.
Volume: 166
Issue: 1
Pages: 15-9
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Publication
12610729 | -
First Author: Droemann D
Year: 2003
Journal: Histochem Cell Biol
Title: Toll-like receptor 2 is expressed by alveolar epithelial cells type II and macrophages in the human lung.
Volume: 119
Issue: 2
Pages: 103-8
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Publication
17449723 | -
First Author: Sheedy FJ
Year: 2007
Journal: J Leukoc Biol
Title: The Troll in Toll: Mal and Tram as bridges for TLR2 and TLR4 signaling.
Volume: 82
Issue: 2
Pages: 196-203
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Publication
18177245 | -
First Author: Bochud PY
Year: 2008
Journal: J Infect Dis
Title: Toll-like receptor 2 (TLR2) polymorphisms are associated with reversal reaction in leprosy.
Volume: 197
Issue: 2
Pages: 253-61
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Publication
10426996 | -
First Author: Aliprantis AO
Year: 1999
Journal: Science
Title: Cell activation and apoptosis by bacterial lipoproteins through toll-like receptor-2.
Volume: 285
Issue: 5428
Pages: 736-9
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Publication
11431423 | J:70578
First Author: Takeuchi O
Year: 2001
Journal: Int Immunol
Title: Discrimination of bacterial lipoproteins by Toll-like receptor 6.
Volume: 13
Issue: 7
Pages: 933-40
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Publication
12646604 | -
First Author: Bochud PY
Year: 2003
Journal: J Immunol
Title: Cutting edge: a Toll-like receptor 2 polymorphism that is associated with lepromatous leprosy is unable to mediate mycobacterial signaling.
Volume: 170
Issue: 7
Pages: 3451-4
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Publication
12594207 | -
First Author: Schröder NW
Year: 2003
Journal: J Biol Chem
Title: Lipoteichoic acid (LTA) of Streptococcus pneumoniae and Staphylococcus aureus activates immune cells via Toll-like receptor (TLR)-2, lipopolysaccharide-binding protein (LBP), and CD14, whereas TLR-4 and MD-2 are not involved.
Volume: 278
Issue: 18
Pages: 15587-94
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Publication
11680785 | -
First Author: Kirschning CJ
Year: 2001
Journal: Int J Med Microbiol
Title: Toll-like receptors: cellular signal transducers for exogenous molecular patterns causing immune responses.
Volume: 291
Issue: 4
Pages: 251-60
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Publication
11441107 | J:114041
First Author: Bulut Y
Year: 2001
Journal: J Immunol
Title: Cooperation of Toll-like receptor 2 and 6 for cellular activation by soluble tuberculosis factor and Borrelia burgdorferi outer surface protein A lipoprotein: role of Toll-interacting protein and IL-1 receptor signaling molecules in Toll-like receptor 2 signaling.
Volume: 167
Issue: 2
Pages: 987-94
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Publication
12697090 | -
First Author: Takeda K
Year: 2002
Journal: J Endotoxin Res
Title: Recognition of lipopeptides by Toll-like receptors.
Volume: 8
Issue: 6
Pages: 459-63
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Protein Domain
IPR027187 | TLR6
Type: Family
Description: Toll-like receptor 6 (TLR6) participates in the innate immune response to Gram-positive bacteria and fungi. TLRs recognize specific molecular patterns present only in micro-organisms. TLR1 and TLR6 are involved in the discrimination of a subtle difference between triacyl and diacyl lipopeptides through interaction with TLR2 []. Cooperatively with TLR2, TLR6 recognises mycoplasmal macrophage-activating lipopeptide-2 (MALP-2), soluble tuberculosis factor (STF), phenol-soluble modulin (PSM) and Borrelia burgdorferi outer surface protein A lipoprotein (OspA-L) []. TLR6 acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response [].
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Protein Domain
IPR027185 | TLR2
Type: Family
Description: Toll-like receptor 2 (TLR2) is a member of the Toll-like receptor (TLR) family, which plays a role in activation of innate immunity and pathogen recognition []. It helps mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components, acting via MyD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response [, , , ]. TLR2 in association with TLR1 or TLR6 is essential for recognising bacterial lipoproteins and lipopeptides [, ]. It also promotes apoptosis in response to lipoproteins [].Genetic variations in TLR2 are associated with susceptibility to leprosy, a chronic disease associated with depressed cellular (but not humoral) immunity [, ].
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Publication
19931471 | J:156189
First Author: Kang JY
Year: 2009
Journal: Immunity
Title: Recognition of lipopeptide patterns by Toll-like receptor 2-Toll-like receptor 6 heterodimer.
Volume: 31
Issue: 6
Pages: 873-84
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Publication
17889651 | J:158053
First Author: Jin MS
Year: 2007
Journal: Cell
Title: Crystal structure of the TLR1-TLR2 heterodimer induced by binding of a tri-acylated lipopeptide.
Volume: 130
Issue: 6
Pages: 1071-82
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Publication
27794068 | J:332284
First Author: Morita N
Year: 2017
Journal: Innate Immun
Title: C4b binding protein negatively regulates TLR1/2 response.
Volume: 23
Issue: 1
Pages: 11-19
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Publication
10426995 | -
First Author: Brightbill HD
Year: 1999
Journal: Science
Title: Host defense mechanisms triggered by microbial lipoproteins through toll-like receptors.
Volume: 285
Issue: 5428
Pages: 732-6
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Publication
26283364 | J:226711
First Author: Koymans KJ
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Structural basis for inhibition of TLR2 by staphylococcal superantigen-like protein 3 (SSL3).
Volume: 112
Issue: 35
Pages: 11018-23
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Publication
18641312 | J:137837
First Author: Vallois D
Year: 2008
Journal: J Immunol
Title: Influence of a non-NK complex region of chromosome 6 on CD4+ invariant NK T cell homeostasis.
Volume: 181
Issue: 3
Pages: 1753-9
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Publication
30952815 | J:274588
First Author: Wang H
Year: 2019
Journal: J Immunol
Title: TLR2 Plays a Pivotal Role in Mediating Mucosal Serotonin Production in the Gut.
Volume: 202
Issue: 10
Pages: 3041-3052
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Publication
33723368 | J:347952
First Author: Udayan S
Year: 2021
Journal: Sci Rep
Title: Macrophage cytokine responses to commensal Gram-positive Lactobacillus salivarius strains are TLR2-independent and Myd88-dependent.
Volume: 11
Issue: 1
Pages: 5896
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Publication
12447442 | J:96773
First Author: Horng T
Year: 2002
Journal: Nature
Title: The adaptor molecule TIRAP provides signalling specificity for Toll-like receptors.
Volume: 420
Issue: 6913
Pages: 329-33
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Publication
22198949 | J:180762
First Author: Liu S
Year: 2012
Journal: J Immunol
Title: TLR2 is a primary receptor for Alzheimer's amyloid β peptide to trigger neuroinflammatory activation.
Volume: 188
Issue: 3
Pages: 1098-107
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Publication
17525261 | J:122150
First Author: Batra A
Year: 2007
Journal: Am J Pathol
Title: Leptin-dependent toll-like receptor expression and responsiveness in preadipocytes and adipocytes.
Volume: 170
Issue: 6
Pages: 1931-41
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Publication
18256364 | J:149925
First Author: Banas MC
Year: 2008
Journal: J Am Soc Nephrol
Title: TLR4 links podocytes with the innate immune system to mediate glomerular injury.
Volume: 19
Issue: 4
Pages: 704-13
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Publication
12941697 | J:85345
First Author: Matsuguchi T
Year: 2003
Journal: EMBO J
Title: JNK-interacting protein 3 associates with Toll-like receptor 4 and is involved in LPS-mediated JNK activation.
Volume: 22
Issue: 17
Pages: 4455-64
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Publication
17312161 | J:144304
First Author: Mayer AK
Year: 2007
Journal: J Immunol
Title: Differential recognition of TLR-dependent microbial ligands in human bronchial epithelial cells.
Volume: 178
Issue: 5
Pages: 3134-42
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Publication
19682928 | J:151842
First Author: Martin B
Year: 2009
Journal: Immunity
Title: Interleukin-17-producing gammadelta T cells selectively expand in response to pathogen products and environmental signals.
Volume: 31
Issue: 2
Pages: 321-30
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Publication
21483755 | J:171659
First Author: Menendez D
Year: 2011
Journal: PLoS Genet
Title: The Toll-like receptor gene family is integrated into human DNA damage and p53 networks.
Volume: 7
Issue: 3
Pages: e1001360
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Publication
21628060 | J:176753
First Author: Zhu W
Year: 2011
Journal: Cell Immunol
Title: Overexpressing autoimmune regulator regulates the expression of toll-like receptors by interacting with their promoters in RAW264.7 cells.
Volume: 270
Issue: 2
Pages: 156-63
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Publication
21385270 | J:187557
First Author: Rose JA
Year: 2011
Journal: Am J Reprod Immunol
Title: Peptidoglycan induces necrosis and regulates cytokine production in murine trophoblast stem cells.
Volume: 66
Issue: 3
Pages: 209-22
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Publication
24892697 | J:218134
First Author: Mariano VS
Year: 2014
Journal: PLoS One
Title: Recognition of TLR2 N-glycans: critical role in ArtinM immunomodulatory activity.
Volume: 9
Issue: 6
Pages: e98512
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Publication
26786104 | J:233729
First Author: Westwell-Roper C
Year: 2016
Journal: J Biol Chem
Title: Differential Activation of Innate Immune Pathways by Distinct Islet Amyloid Polypeptide (IAPP) Aggregates.
Volume: 291
Issue: 17
Pages: 8908-17
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Publication
31255680 | J:295583
 
First Author: Manners MT
Year: 2019
Journal: Brain Behav Immun
Title: CREB deletion increases resilience to stress and downregulates inflammatory gene expression in the hippocampus.
Volume: 81
Pages: 388-398
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Publication
19139093 | J:313312
First Author: Kurokawa K
Year: 2009
Journal: J Biol Chem
Title: The Triacylated ATP Binding Cluster Transporter Substrate-binding Lipoprotein of Staphylococcus aureus Functions as a Native Ligand for Toll-like Receptor 2.
Volume: 284
Issue: 13
Pages: 8406-11
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Publication
34866574 | J:317266
   
First Author: Khan S
Year: 2021
Journal: Elife
Title: SARS-CoV-2 spike protein induces inflammation via TLR2-dependent activation of the NF-κB pathway.
Volume: 10
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Publication
31993047 | J:297951
 
First Author: Kiripolsky J
Year: 2019
Journal: Front Immunol
Title: Activation of Myd88-Dependent TLRs Mediates Local and Systemic Inflammation in a Mouse Model of Primary Sjögren's Syndrome.
Volume: 10
Pages: 2963
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Publication
13679373 | J:86781
First Author: Radons J
Year: 2003
Journal: J Biol Chem
Title: The interleukin 1 (IL-1) receptor accessory protein Toll/IL-1 receptor domain: analysis of putative interaction sites in vitro mutagenesis and molecular modeling.
Volume: 278
Issue: 49
Pages: 49145-53
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Publication
23951309 | J:204925
First Author: Brodziak F
Year: 2013
Journal: PLoS One
Title: Differences in mucosal gene expression in the colon of two inbred mouse strains after colonization with commensal gut bacteria.
Volume: 8
Issue: 8
Pages: e72317
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Protein
A0A0J9YTV4
Organism: Mus musculus/domesticus
Length: 102  
Fragment?: true
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Protein
Q9EPW9
Organism: Mus musculus/domesticus
Length: 795  
Fragment?: false
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Protein
Q9QUN7
Organism: Mus musculus/domesticus
Length: 784  
Fragment?: false
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Protein
Q3UV88
Organism: Mus musculus/domesticus
Length: 806  
Fragment?: false
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Protein
Q811T5
Organism: Mus musculus/domesticus
Length: 784  
Fragment?: false
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Protein
Q0PM14
Organism: Mus musculus/domesticus
Length: 806  
Fragment?: false
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Protein
Q8K3D9
Organism: Mus musculus/domesticus
Length: 784  
Fragment?: false
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Protein
Q7TPC5
Organism: Mus musculus/domesticus
Length: 806  
Fragment?: false
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Protein
G3X8Y8
Organism: Mus musculus/domesticus
Length: 784  
Fragment?: false
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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