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Search results 101 to 128 out of 128 for Wwc1

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Type Details Score
Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Allele
Wwc1<em1Smoc> | MGI:7293196
Name: WW, C2 and coiled-coil domain containing 1; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Strain
MGI:6429804 | C57BL/6J-Wwc1<em1Smoc>/Smoc
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Allele
Tg(Wwc1-EGFP)OJ47Gsat | MGI:4940614
Name: transgene insertion OJ47, GENSAT Project at Rockefeller University
Allele Type: Transgenic
Attribute String: Reporter
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Strain
MGI:5004347 | STOCK Tg(Wwc1-EGFP)OJ47Gsat/Mmucd
Attribute String: mutant stock, transgenic
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HT Experiment
GSE116382 | Transcriptome analysis of WWC2-deficient E11.5 embryos
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Publication
25832504 | J:222743
 
First Author: Basu-Roy U
Year: 2015
Journal: Nat Commun
Title: Sox2 antagonizes the Hippo pathway to maintain stemness in cancer cells.
Volume: 6
Pages: 6411
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Publication
12559952 | -
First Author: Kremerskothen J
Year: 2003
Journal: Biochem Biophys Res Commun
Title: Characterization of KIBRA, a novel WW domain-containing protein.
Volume: 300
Issue: 4
Pages: 862-7
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Publication
24682284 | -
First Author: Wennmann DO
Year: 2014
Journal: Mol Biol Evol
Title: Evolutionary and molecular facts link the WWC protein family to Hippo signaling.
Volume: 31
Issue: 7
Pages: 1710-23
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Publication
28815883 | -
First Author: Zhang Y
Year: 2017
Journal: J Cell Mol Med
Title: WWC2 is an independent prognostic factor and prevents invasion via Hippo signalling in hepatocellular carcinoma.
Volume: 21
Issue: 12
Pages: 3718-3729
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Publication
23778582 | -
 
First Author: Duning K
Year: 2013
Journal: Transl Psychiatry
Title: Common exonic missense variants in the C2 domain of the human KIBRA protein modify lipid binding and cognitive performance.
Volume: 3
Pages: e272
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Protein Domain
IPR037771 | C2_WWC
Type: Domain
Description: The WWC (WW-and-C2-domain-containing protein) family negatively regulates cell proliferation and organ growth by suppressing the transcriptional activityof YAP, a major effector of the Hippo pathway. They activate large tumour suppressor 1 and 2 kinases (LATS1/2), which in turn phosphorylates the transcriptional co-activator YAP [, ]. Their two amino terminal WW domains mediate binding to target proteins, whereas the internal C2 domain is required for membrane association. WWC family members include WWC1 (also known as KIBRA), WWC2 and WWC3 [].C2 domains fold into an 8-standed β-sandwich that can adopt 2 structural arrangements: type I and type II, distinguished by a circular permutation involving their N- and C-terminal beta strands. Many C2 domains are Ca2+-dependent membrane-targeting modules that bind a wide variety of substances including bind phospholipids, inositol polyphosphates, and intracellular proteins. Whereas the majority of known C2 domains have a role in Ca2+-dependent vesicle membrane association, these protein modules are also involved in Ca2+-insensitive membrane targeting as well as in intracellular protein-protein interactions. The C2 domain of KIBRA has been shown to have Ca2+-dependent-binding specificity for monophosphorylated phosphatidylinositols [].
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Protein
Q5SXA9
Organism: Mus musculus/domesticus
Length: 1104  
Fragment?: false
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Protein
Q6NXJ0
Organism: Mus musculus/domesticus
Length: 1187  
Fragment?: false
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Protein
Q0KIX1
Organism: Mus musculus/domesticus
Length: 1094  
Fragment?: false
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Publication
- | J:100256
     
First Author: The Gene Expression Nervous System Atlas (GENSAT) Project, The Rockefeller University (New York, NY)
Year: 2005
Journal: Database Download
Title: MGI download of GENSAT transgene data
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