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Search results 1001 to 1100 out of 1106 for Cbs

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Type Details Score
GXD Expression      
Probe: MGI:6695937
Assay Type: Immunohistochemistry
Annotation Date: 2021-05-04
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:6696056
Age: postnatal month 2
Specimen Label: 3b fl/fl (Six2-Cre)
Detected: false
Specimen Num: 4
GXD Expression  
Probe: MGI:6771669
Assay Type: Immunohistochemistry
Annotation Date: 2021-10-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2839326
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6771694
Age: embryonic day 18.5
Image: 1H +/+
Specimen Label: 1H +/+
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6771669
Assay Type: Immunohistochemistry
Annotation Date: 2021-10-15
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:2839326
Stage: TS26
Assay Id: MGI:6771694
Age: embryonic day 18.5
Image: 1H -/-
Specimen Label: 1H -/-
Detected: false
Specimen Num: 2
Publication    
First Author: Wang C
Year: 2000
Journal: GenBank Submission
Title: Mus musculus ancient conserved domain protein 2 (Acdp2) mRNA, complete cds
Pages: AF216961
Publication    
First Author: Wang C
Year: 2000
Journal: GenBank Submission
Title: Mus musculus ancient conserved domain protein 4 (Acdp4) mRNA, complete cds
Pages: AF216963
Publication
First Author: Hattori M
Year: 2007
Journal: Nature
Title: Crystal structure of the MgtE Mg2+ transporter.
Volume: 448
Issue: 7157
Pages: 1072-5
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein
Organism: Mus musculus/domesticus
Length: 348  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 345  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 290  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 320  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 218  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 82  
Fragment?: true
Publication
First Author: Stanĕk D
Year: 2003
Journal: J Cell Biol
Title: Targeting of U4/U6 small nuclear RNP assembly factor SART3/p110 to Cajal bodies.
Volume: 160
Issue: 4
Pages: 505-16
Publication
First Author: Piruat JI
Year: 2004
Journal: Mol Cell Biol
Title: The mitochondrial SDHD gene is required for early embryogenesis, and its partial deficiency results in persistent carotid body glomus cell activation with full responsiveness to hypoxia.
Volume: 24
Issue: 24
Pages: 10933-40
Publication
First Author: Hui S
Year: 2011
Journal: Circ Res
Title: Peptide-mediated disruption of calmodulin-cyclin E interactions inhibits proliferation of vascular smooth muscle cells and neointima formation.
Volume: 108
Issue: 9
Pages: 1053-62
Publication
First Author: Tucker KE
Year: 2001
Journal: J Cell Biol
Title: Residual Cajal bodies in coilin knockout mice fail to recruit Sm snRNPs and SMN, the spinal muscular atrophy gene product.
Volume: 154
Issue: 2
Pages: 293-307
Publication
First Author: Vacík T
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: Segmental trisomy of chromosome 17: a mouse model of human aneuploidy syndromes.
Volume: 102
Issue: 12
Pages: 4500-5
Publication
First Author: Molina-Holgado F
Year: 2003
Journal: J Neurosci
Title: Endogenous interleukin-1 receptor antagonist mediates anti-inflammatory and neuroprotective actions of cannabinoids in neurons and glia.
Volume: 23
Issue: 16
Pages: 6470-4
Publication  
First Author: Tapia O
Year: 2017
Journal: Neurobiol Dis
Title: Cellular bases of the RNA metabolism dysfunction in motor neurons of a murine model of spinal muscular atrophy: Role of Cajal bodies and the nucleolus.
Volume: 108
Pages: 83-99
Publication
First Author: Gupta S
Year: 2008
Journal: Hum Mutat
Title: Cystathionine beta-synthase p.S466L mutation causes hyperhomocysteinemia in mice.
Volume: 29
Issue: 8
Pages: 1048-54
Publication
First Author: Prudova A
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: S-adenosylmethionine stabilizes cystathionine beta-synthase and modulates redox capacity.
Volume: 103
Issue: 17
Pages: 6489-94
Publication
First Author: Messina V
Year: 2012
Journal: PLoS One
Title: The RNA binding protein SAM68 transiently localizes in the chromatoid body of male germ cells and influences expression of select microRNAs.
Volume: 7
Issue: 6
Pages: e39729
Publication
First Author: Jiang Z
Year: 2015
Journal: PLoS One
Title: Role of hydrogen sulfide in early blood-brain barrier disruption following transient focal cerebral ischemia.
Volume: 10
Issue: 2
Pages: e0117982
Publication  
First Author: Katsouda A
Year: 2023
Journal: Front Pharmacol
Title: CTH/MPST double ablation results in enhanced vasorelaxation and reduced blood pressure via upregulation of the eNOS/sGC pathway.
Volume: 14
Pages: 1090654
Publication
First Author: Lecarpentier Y
Year: 2008
Journal: Biophys J
Title: Cardiac Myosin-binding protein C modulates the tuning of the molecular motor in the heart.
Volume: 95
Issue: 2
Pages: 720-8
Publication  
First Author: Rahimi A
Year: 2015
Journal: Neuroscience
Title: Interaction between the protective effects of cannabidiol and palmitoylethanolamide in experimental model of multiple sclerosis in C57BL/6 mice.
Volume: 290
Pages: 279-87
Publication  
First Author: Krejčí J
Year: 2017
Journal: Stem Cells Int
Title: Neural Differentiation in HDAC1-Depleted Cells Is Accompanied by Coilin Downregulation and the Accumulation of Cajal Bodies in Nucleoli.
Volume: 2017
Pages: 1021240
Publication
First Author: Chan EK
Year: 1994
Journal: Nucleic Acids Res
Title: Structure, expression and chromosomal localization of human p80-coilin gene.
Volume: 22
Issue: 21
Pages: 4462-9
Publication
First Author: Peña-Münzenmayer G
Year: 2005
Journal: J Cell Sci
Title: Basolateral localization of native ClC-2 chloride channels in absorptive intestinal epithelial cells and basolateral sorting encoded by a CBS-2 domain di-leucine motif.
Volume: 118
Issue: Pt 18
Pages: 4243-52
Publication
First Author: Li L
Year: 2006
Journal: Mol Biol Cell
Title: Dynamic nature of cleavage bodies and their spatial relationship to DDX1 bodies, Cajal bodies, and gems.
Volume: 17
Issue: 3
Pages: 1126-40
Publication
First Author: Kundu S
Year: 2014
Journal: Biochim Biophys Acta
Title: Hydrogen sulfide mitigates hyperglycemic remodeling via liver kinase B1-adenosine monophosphate-activated protein kinase signaling.
Volume: 1843
Issue: 12
Pages: 2816-26
Publication
First Author: Mo S
Year: 2018
Journal: Biochem Biophys Res Commun
Title: Cystathionine gamma lyase-H2S contributes to osteoclastogenesis during bone remodeling induced by mechanical loading.
Volume: 501
Issue: 2
Pages: 471-477
Publication
First Author: Majtan T
Year: 2019
Journal: FASEB J
Title: Behavior, body composition, and vascular phenotype of homocystinuric mice on methionine-restricted diet or enzyme replacement therapy.
Volume: 33
Issue: 11
Pages: 12477-12486
Publication  
First Author: Rawat P
Year: 2017
Journal: Mol Cell Biol
Title: Chromatin Domain Organization of the TCRb Locus and Its Perturbation by Ectopic CTCF Binding.
Volume: 37
Issue: 9
Publication
First Author: Li HY
Year: 2016
Journal: J Biol Chem
Title: An Intrinsically Disordered Motif Mediates Diverse Actions of Monomeric C-reactive Protein.
Volume: 291
Issue: 16
Pages: 8795-804
Publication
First Author: Wang W
Year: 2018
Journal: Am J Physiol Renal Physiol
Title: Endogenous H2S sensitizes PAR4-induced bladder pain.
Volume: 314
Issue: 6
Pages: F1077-F1086
Publication  
First Author: Kundu S
Year: 2015
Journal: Nitric Oxide
Title: MMP-9- and NMDA receptor-mediated mechanism of diabetic renovascular remodeling and kidney dysfunction: hydrogen sulfide is a key modulator.
Volume: 46
Pages: 172-85
Publication
First Author: Pereira PL
Year: 2009
Journal: Hum Mol Genet
Title: A new mouse model for the trisomy of the Abcg1-U2af1 region reveals the complexity of the combinatorial genetic code of down syndrome.
Volume: 18
Issue: 24
Pages: 4756-69
Protein
Organism: Mus musculus/domesticus
Length: 96  
Fragment?: true
Protein Domain
Type: Domain
Description: This presumed domain (used to be named as DUF39) is about is about 360 residues long. The function of this domain is not clear. It is found at N terminus in some proteins that have two C-terminal cystathionine beta-synthase (CBS) domains, such as MJ0100 from Methanocaldococcus jannaschii. This domain can also be found in proteins that contain two C-terminal inserted Fe4S domains []. In Methanocaldococcus jannaschii, MJ0100 (also known as MA1821) is involved in Hcy (homocysteine) biosynthesis. Its CBS domains bind S-adenosyl-l-methionine (SAM) and 5'-methylthioadenosine (MTA), which induce a conformational change consistent with regulatory function. Another protein in the homocysteine biosynthesis pathway, MA1822, is involved in the reduction of the disulfide formed in MA1821 during the conversion of Asa (aspartate semialdehyde) to Hcy [, ].The DUF39-CBS and DUF39-ferredoxin architectures repeatedly occur together in the genomes of methanogenic Archaea, suggesting they may be of diverged function. This is consistent with a phylogenetic reconstruction of the DUF39 family, which clearly distinguishes the CBS-associated and ferredoxin-associated DUF39s [].
Publication
First Author: Funato Y
Year: 2017
Journal: J Hypertens
Title: Renal function of cyclin M2 Mg2+ transporter maintains blood pressure.
Volume: 35
Issue: 3
Pages: 585-592
Publication
First Author: Funato Y
Year: 2021
Journal: Nat Commun
Title: Importance of the renal ion channel TRPM6 in the circadian secretion of renin to raise blood pressure.
Volume: 12
Issue: 1
Pages: 3683
Publication  
First Author: Liu J
Year: 2021
Journal: Front Pharmacol
Title: Chronoeffects of the Herbal Medicines Puerariae radix and Coptidis rhizoma in Mice: A Potential Role of REV-ERBα.
Volume: 12
Pages: 707844
Publication  
First Author: Otsubo T
Year: 2011
Journal: Front Cell Neurosci
Title: Differential Expression of Large-Conductance Ca-Activated K Channels in the Carotid Body between DBA/2J and A/J Strains of Mice.
Volume: 5
Pages: 19
Publication
First Author: Ilenwabor BP
Year: 2022
Journal: Am J Physiol Renal Physiol
Title: SLC41A1 knockout mice display normal magnesium homeostasis.
Volume: 323
Issue: 5
Pages: F553-F563
Publication  
First Author: Peleli M
Year: 2020
Journal: Biochem Pharmacol
Title: Cardiovascular phenotype of mice lacking 3-mercaptopyruvate sulfurtransferase.
Volume: 176
Pages: 113833
Publication
First Author: Chrysis D
Year: 2001
Journal: J Neurosci
Title: Insulin-like growth factor-I overexpression attenuates cerebellar apoptosis by altering the expression of Bcl family proteins in a developmentally specific manner.
Volume: 21
Issue: 5
Pages: 1481-9
Publication
First Author: Dahlhoff C
Year: 2013
Journal: PLoS One
Title: Hepatic methionine homeostasis is conserved in C57BL/6N mice on high-fat diet despite major changes in hepatic one-carbon metabolism.
Volume: 8
Issue: 3
Pages: e57387
Publication  
First Author: Shentu Y
Year: 2024
Journal: Exp Neurol
Title: Hydrogen sulfide ameliorates lipopolysaccharide-induced anxiety-like behavior by inhibiting checkpoint kinase 1 activation in the hippocampus of mice.
Volume: 371
Pages: 114586
Publication  
First Author: Threadgill DS
Year: 1989
Journal: Cytogenet Cell Genet
Title: Comparative mapping of HSA 21/MMU 16 homologs in the bovine.
Volume: 51
Pages: 1090-1091 (Abstr.)
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein
Organism: Mus musculus/domesticus
Length: 187  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 84  
Fragment?: true
Protein Domain
Type: Domain
Description: Prokaryotic cells have a defence mechanism against a sudden heat-shock stress. Commonly, they induce a set of proteins that protect cellular proteins from being denatured by heat. Among such proteins are the GroE and DnaK chaperones whose transcription is regulated by a heat-shock repressor protein HrcA. HrcA is a winged helix-turn-helix repressor that negatively regulates the transcription of dnaK and groE operons by binding the upstream CIRCE (controlling inverted repeat of chaperone expression) element. In Bacillus subtilis this element is a perfect 9 base pair inverted repeat separated by a 9 base pair spacer. The crystal structure of a heat-inducible transcriptional repressor, HrcA, from Thermotoga maritima has been reported at 2.2A resolution. HrcA is composed of three domains: an N-terminal winged helix-turn-helix domain (WHTH), a GAF-like domain, and an inserted dimerizing domain (IDD). The IDD shows a unique structural fold with an anti-parallel β-sheet composed of three β-strands sided by four α-helices. HrcA crystallises as a dimer, which is formed through hydrophobic contact between the IDDs and a limited contact that involves conserved residues between the GAF-like domains []. The structural studies suggest that the inactive form of HrcA is the dimer and this is converted to its DNA-binding form by interaction with GroEL, which binds to a conserved C-terminal sequence region [, ]. Comparison of the HrcA-CIRCE complexes from B. subtilis and Bacillus thermoglucosidasius (Geobacillus thermoglucosidasius), which grow at vastly different ranges of temperature shows that the thermostability profiles were consistent with the difference in the growth temperatures suggesting that HrcA can function as a thermosensor to detect temperature changes in cells []. Any increase in temperature causes the dissociation of the HrcA from the CIRCE complex with the concomitant activation of transcription of the groE and dnaK operons. This domain represents the winged helix-turn-helix DNA-binding domain which is located close to the N terminus of HrcA. This domain is also found at the N terminus of a set of uncharacterised proteins that have two C-terminal CBS domains.
Protein Domain
Type: Family
Description: AMPK, a serine/threonine protein kinase (STK), catalyzes the transfer of the gamma-phosphoryl group from ATP to S/T residues on protein substrates. It acts as a sensor for the energy status of the cell and is activated by cellular stresses that lead to ATP depletion such as hypoxia, heat shock, and glucose deprivation, among others. AMPK is a heterotrimer of three subunits: alpha, beta, and gamma []. The alpha subunit is the catalytic subunit and it contains an N-terminal kinase domain, a putative autoinhibitory domain (AID) and a C-terminal region required for beta subunit binding. The beta scaffolding subunit mediates AMPK assembly by bridging alpha and gamma subunits. The C-terminal domain of the AMPK alpha 1 subunit interacts with the C-terminal region of the beta subunit to form a tight alpha-beta complex that is associated with the gamma subunit. The AMPK alpha subunit auto-inhibitory region interacts with the kinase domain; this inhibition is negated by the interaction with the AMPK gamma subunit [].AMPK has been implicated in a number of diseases related to energy metabolism including type 2 diabetes, obesity and cancer [, ]. AMPK is activated by rising AMP concentrations coupled with falling ATP concentrations. Activation of AMPK is also dependent on the phosphorylation of alpha subunit by upstream kinases such as LKB1 [].The regulatory gamma subunit binds adenine nucleotides in the highly conserved nucleotide-binding domain consisting of four CBS motifs []. The gamma-1 subunit is the most abundant and shows wide tissue expression, as does gamma-2 whereas the gamma-3 isoform is almost exclusively expressed in skeletal muscle [].
Protein Domain
Type: Family
Description: AMPK, a serine/threonine protein kinase (STK), catalyzes the transfer of the gamma-phosphoryl group from ATP to S/T residues on protein substrates. It acts as a sensor for the energy status of the cell and is activated by cellular stresses that lead to ATP depletion such as hypoxia, heat shock, and glucose deprivation, among others. AMPK is a heterotrimer of three subunits: alpha, beta, and gamma []. The alpha subunit is the catalytic subunit and it contains an N-terminal kinase domain, a putative autoinhibitory domain (AID) and a C-terminal region required for beta subunit binding. The beta scaffolding subunit mediates AMPK assembly by bridging alpha and gamma subunits. The C-terminal domain of the AMPK alpha 1 subunit interacts with the C-terminal region of the beta subunit to form a tight alpha-beta complex that is associated with the gamma subunit. The AMPK alpha subunit auto-inhibitory region interacts with the kinase domain; this inhibition is negated by the interaction with the AMPK gamma subunit [].AMPK has been implicated in a number of diseases related to energy metabolism including type 2 diabetes, obesity and cancer [, ]. AMPK is activated by rising AMP concentrations coupled with falling ATP concentrations. Activation of AMPK is also dependent on the phosphorylation of alpha subunit by upstream kinases such as LKB1 [].The regulatory gamma subunit binds adenine nucleotides in the highly conserved nucleotide-binding domain consisting of four CBS motifs []. The gamma-1 subunit is the most abundant and shows wide tissue expression, as does gamma-2 whereas the gamma-3 isoform is almost exclusively expressed in skeletal muscle [].
Protein Domain
Type: Family
Description: AMPK, a serine/threonine protein kinase (STK), catalyzes the transfer of the gamma-phosphoryl group from ATP to S/T residues on protein substrates. It acts as a sensor for the energy status of the cell and is activated by cellular stresses that lead to ATP depletion such as hypoxia, heat shock, and glucose deprivation, among others. AMPK is a heterotrimer of three subunits: alpha, beta, and gamma []. The alpha subunit is the catalytic subunit and it contains an N-terminal kinase domain, a putative autoinhibitory domain (AID) and a C-terminal region required for beta subunit binding. The beta scaffolding subunit mediates AMPK assembly by bridging alpha and gamma subunits. The C-terminal domain of the AMPK alpha 1 subunit interacts with the C-terminal region of the beta subunit to form a tight alpha-beta complex that is associated with the gamma subunit. The AMPK alpha subunit auto-inhibitory region interacts with the kinase domain; this inhibition is negated by the interaction with the AMPK gamma subunit [].AMPK has been implicated in a number of diseases related to energy metabolism including type 2 diabetes, obesity and cancer [, ]. AMPK is activated by rising AMP concentrations coupled with falling ATP concentrations. Activation of AMPK is also dependent on the phosphorylation of alpha subunit by upstream kinases such as LKB1 [].The regulatory gamma subunit binds adenine nucleotides in the highly conserved nucleotide-binding domain consisting of four CBS motifs []. The gamma-1 subunit is the most abundant and shows wide tissue expression, as does gamma-2 whereas the gamma-3 isoform is almost exclusively expressed in skeletal muscle [].
Publication
First Author: Pinter K
Year: 2013
Journal: J Muscle Res Cell Motil
Title: Localisation of AMPK γ subunits in cardiac and skeletal muscles.
Volume: 34
Issue: 5-6
Pages: 369-78
Publication  
First Author: Cheung PC
Year: 2000
Journal: Biochem J
Title: Characterization of AMP-activated protein kinase gamma-subunit isoforms and their role in AMP binding.
Volume: 346 Pt 3
Pages: 659-69
Publication
First Author: Caballero-Eraso C
Year: 2019
Journal: J Physiol
Title: Leptin acts in the carotid bodies to increase minute ventilation during wakefulness and sleep and augment the hypoxic ventilatory response.
Volume: 597
Issue: 1
Pages: 151-172
Publication
First Author: Berciano MT
Year: 2020
Journal: Sci Rep
Title: Nusinersen ameliorates motor function and prevents motoneuron Cajal body disassembly and abnormal poly(A) RNA distribution in a SMA mouse model.
Volume: 10
Issue: 1
Pages: 10738
Publication
First Author: Yamazaki D
Year: 2013
Journal: PLoS Genet
Title: Basolateral Mg2+ extrusion via CNNM4 mediates transcellular Mg2+ transport across epithelia: a mouse model.
Volume: 9
Issue: 12
Pages: e1003983
Publication
First Author: Zhang L
Year: 2012
Journal: Bioeng Bugs
Title: Genetic analysis of Down syndrome facilitated by mouse chromosome engineering.
Volume: 3
Issue: 1
Pages: 8-12
Publication
First Author: Gupta M
Year: 2016
Journal: Mamm Genome
Title: Mouse models of Down syndrome: gene content and consequences.
Volume: 27
Issue: 11-12
Pages: 538-555
Publication
First Author: Xu H
Year: 2005
Journal: BMC Cell Biol
Title: A novel EB-1/AIDA-1 isoform, AIDA-1c, interacts with the Cajal body protein coilin.
Volume: 6
Issue: 1
Pages: 23
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Funato Y
Year: 2014
Journal: J Clin Invest
Title: Membrane protein CNNM4-dependent Mg2+ efflux suppresses tumor progression.
Volume: 124
Issue: 12
Pages: 5398-410
Publication
First Author: Sanz P
Year: 2008
Journal: Curr Protein Pept Sci
Title: AMP-activated protein kinase: structure and regulation.
Volume: 9
Issue: 5
Pages: 478-92
Publication
First Author: Cool B
Year: 2006
Journal: Cell Metab
Title: Identification and characterization of a small molecule AMPK activator that treats key components of type 2 diabetes and the metabolic syndrome.
Volume: 3
Issue: 6
Pages: 403-16
Publication
First Author: Shackelford DB
Year: 2009
Journal: Nat Rev Cancer
Title: The LKB1-AMPK pathway: metabolism and growth control in tumour suppression.
Volume: 9
Issue: 8
Pages: 563-75
Publication
First Author: Woods A
Year: 2003
Journal: Curr Biol
Title: LKB1 is the upstream kinase in the AMP-activated protein kinase cascade.
Volume: 13
Issue: 22
Pages: 2004-8
Publication
First Author: Zhu L
Year: 2011
Journal: Structure
Title: Structural insights into the architecture and allostery of full-length AMP-activated protein kinase.
Volume: 19
Issue: 4
Pages: 515-22
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Stuiver M
Year: 2011
Journal: Am J Hum Genet
Title: CNNM2, encoding a basolateral protein required for renal Mg2+ handling, is mutated in dominant hypomagnesemia.
Volume: 88
Issue: 3
Pages: 333-43
Publication
First Author: Franken GAC
Year: 2021
Journal: Sci Rep
Title: Cyclin M2 (CNNM2) knockout mice show mild hypomagnesaemia and developmental defects.
Volume: 11
Issue: 1
Pages: 8217
Publication
First Author: Liu J
Year: 2005
Journal: J Mol Biol
Title: Crystal structure of a heat-inducible transcriptional repressor HrcA from Thermotoga maritima: structural insight into DNA binding and dimerization.
Volume: 350
Issue: 5
Pages: 987-96
Publication
First Author: Kwon HY
Year: 2009
Journal: Mol Cells
Title: Reduction-sensitive and cysteine residue-mediated Streptococcus pneumoniae HrcA oligomerization in vitro.
Volume: 27
Issue: 2
Pages: 149-57
Publication
First Author: Hitomi M
Year: 2003
Journal: J Bacteriol
Title: Identification of a helix-turn-helix motif of Bacillus thermoglucosidasius HrcA essential for binding to the CIRCE element and thermostability of the HrcA-CIRCE complex, indicating a role as a thermosensor.
Volume: 185
Issue: 1
Pages: 381-5
Publication
First Author: Kasowitz SD
Year: 2018
Journal: PLoS Genet
Title: Nuclear m6A reader YTHDC1 regulates alternative polyadenylation and splicing during mouse oocyte development.
Volume: 14
Issue: 5
Pages: e1007412
Publication
First Author: Yu C
Year: 2016
Journal: Cell Res
Title: Oocyte-expressed yes-associated protein is a key activator of the early zygotic genome in mouse.
Volume: 26
Issue: 3
Pages: 275-87
Publication      
First Author: European Mouse Mutant Archive
Year: 2003
Journal: Unpublished
Title: Information obtained from the European Mouse Mutant Archive (EMMA)
Publication        
First Author: The Gene Ontology Consortium
Year: 2016
Title: Automatic assignment of GO terms using logical inference, based on on inter-ontology links
Publication
First Author: Ko MS
Year: 2000
Journal: Development
Title: Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development.
Volume: 127
Issue: 8
Pages: 1737-49
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
Publication
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
Publication      
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
Publication      
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
Publication
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
Publication
First Author: Koscielny G
Year: 2014
Journal: Nucleic Acids Res
Title: The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Volume: 42
Issue: Database issue
Pages: D802-9
Publication      
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
Publication      
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582