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Search results 1001 to 1100 out of 1127 for Six1

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Type Details Score
Publication
14660441 | J:87048
First Author: Gu G
Year: 2004
Journal: Development
Title: Global expression analysis of gene regulatory pathways during endocrine pancreatic development.
Volume: 131
Issue: 1
Pages: 165-79
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Publication
18023262 | J:130227
First Author: Millien G
Year: 2008
Journal: Gene Expr Patterns
Title: Characterization of the mid-foregut transcriptome identifies genes regulated during lung bud induction.
Volume: 8
Issue: 2
Pages: 124-39
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Publication
33795231 | J:305429
 
First Author: Kaiser M
Year: 2021
Journal: Development
Title: Regulation of otocyst patterning by Tbx2 and Tbx3 is required for inner ear morphogenesis in the mouse.
Volume: 148
Issue: 8
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Publication
39798644 | J:361454
 
First Author: Jasmine
Year: 2025
Journal: Dev Biol
Title: Epithelial and mesenchymal compartments of the developing bladder and urethra display spatially distinct gene expression patterns.
Volume: 520
Pages: 155-170
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Publication
20843830 | J:166958
First Author: Yates LL
Year: 2010
Journal: Hum Mol Genet
Title: The planar cell polarity gene Vangl2 is required for mammalian kidney-branching morphogenesis and glomerular maturation.
Volume: 19
Issue: 23
Pages: 4663-76
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Publication
35084365 | J:326026
First Author: Prokopuk L
Year: 2022
Journal: Reproduction
Title: An essential role for Polycomb Repressive Complex 2 in the mouse ovary.
Volume: 163
Issue: 3
Pages: 167-182
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Publication
32857879 | J:332131
First Author: Perera SN
Year: 2020
Journal: Glia
Title: Insights into olfactory ensheathing cell development from a laser-microdissection and transcriptome-profiling approach.
Volume: 68
Issue: 12
Pages: 2550-2584
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Publication
24146773 | J:209112
First Author: Shimizu H
Year: 2013
Journal: PLoS One
Title: The AERO system: a 3D-like approach for recording gene expression patterns in the whole mouse embryo.
Volume: 8
Issue: 10
Pages: e75754
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Publication
20932939 | J:168654
First Author: Chung YC
Year: 2011
Journal: Gene Expr Patterns
Title: Screening large numbers of expression patterns of transcription factors in late stages of the mouse thymus.
Volume: 11
Issue: 1-2
Pages: 84-92
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Publication
22988430 | J:190636
 
First Author: Wiese CB
Year: 2012
Journal: Front Neurosci
Title: A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.
Volume: 6
Pages: 130
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Publication
20059953 | J:156017
First Author: Yokoyama S
Year: 2009
Journal: Dev Cell
Title: A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58.
Volume: 17
Issue: 6
Pages: 836-48
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Publication
- | J:265051
     
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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Publication
15618518 | J:91257
First Author: Gray PA
Year: 2004
Journal: Science
Title: Mouse brain organization revealed through direct genome-scale TF expression analysis.
Volume: 306
Issue: 5705
Pages: 2255-7
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Publication
24952961 | J:215487
First Author: Thompson CL
Year: 2014
Journal: Neuron
Title: A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Volume: 83
Issue: 2
Pages: 309-323
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Publication
- | J:171409
     
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
26687066 | J:234379
 
First Author: Towers CG
Year: 2015
Journal: Nat Commun
Title: The Six1 oncoprotein downregulates p53 via concomitant regulation of RPL26 and microRNA-27a-3p.
Volume: 6
Pages: 10077
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Publication
19726883 | J:152693
First Author: McCoy EL
Year: 2009
Journal: J Clin Invest
Title: Six1 expands the mouse mammary epithelial stem/progenitor cell pool and induces mammary tumors that undergo epithelial-mesenchymal transition.
Volume: 119
Issue: 9
Pages: 2663-77
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GXD Expression
GXD Expression
 
Probe: MGI:7720085
Assay Type: Immunohistochemistry
Annotation Date: 2024-09-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1760621
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:7720116
Age: embryonic day 13.5
Note: Coexpressed with Six1 in the apical cells.
Specimen Label: 2Ca/d/e
Detected: true
Specimen Num: 1
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Publication
26500063 | J:226084
First Author: Adrados I
Year: 2016
Journal: Oncogene
Title: The homeoprotein SIX1 controls cellular senescence through the regulation of p16INK4A and differentiation-related genes.
Volume: 35
Issue: 27
Pages: 3485-94
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HT Experiment
E-GEOD-50023 | Six1 homeoprotein drives myofiber type IIA specialization in soleus muscle
Series Id: GSE50023
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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GXD Expression
GXD Expression
 
Probe: MGI:7720092
Assay Type: Immunohistochemistry
Annotation Date: 2024-09-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1760621
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:7720114
Age: embryonic day 13.5
Note: Coexpressed with Six1 in the apical and basal layers.
Specimen Label: 2Aa/d/e
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:7720093
Assay Type: Immunohistochemistry
Annotation Date: 2024-09-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1760621
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:7720115
Age: embryonic day 13.5
Note: Coexpressed with Six1 in the basal layer cells.
Specimen Label: 2Ba/d/e
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:7720093
Assay Type: Immunohistochemistry
Annotation Date: 2024-09-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1760624
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:7720115
Age: embryonic day 16.5
Note: Coexpressed with Six1 in the basal layer cells.
Specimen Label: 2Da/d/e
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:6504940
Assay Type: Immunohistochemistry
Annotation Date: 2021-02-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1640617
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:6504949
Age: embryonic day 10.5
Image: 4A
Note: Co-expression with Six1 in nuclei of myogenic progenitor cells.
Specimen Label: 4A
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:4833962
Assay Type: RNA in situ
Annotation Date: 2010-10-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1606912
Pattern: Regionally restricted
Stage: TS12
Assay Id: MGI:4833966
Age: embryonic day 8.0
Note: Expression is present in the anterior neural ridge. There was overlap with Six1 expression.
Specimen Label: Not shown
Detected: true
Specimen Num: 1
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Publication
21706047 | -
First Author: Farabaugh SM
Year: 2012
Journal: Oncogene
Title: Eya2 is required to mediate the pro-metastatic functions of Six1 via the induction of TGF-β signaling, epithelial-mesenchymal transition, and cancer stem cell properties.
Volume: 31
Issue: 5
Pages: 552-62
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Publication
11978764 | -
First Author: Sato S
Year: 2002
Journal: Hum Mol Genet
Title: Identification of transcriptional targets for Six5: implication for the pathogenesis of myotonic dystrophy type 1.
Volume: 11
Issue: 9
Pages: 1045-58
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Interaction Experiment
Ahmed M (2012)
Description: EYA1 and SIX1 drive the neuronal developmental program in cooperation with the SWI/SNF chromatin-remodeling complex and SOX2 in the mammalian inner ear.
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DO Term
DOID:0110553 | autosomal dominant nonsyndromic deafness 23
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Allele
Eya1<tm4(Six1)Px> | MGI:7328385
Name: EYA transcriptional coactivator and phosphatase 1; targeted mutation 4, Pin-Xian Xu
Allele Type: Targeted
Attribute String: Inserted expressed sequence
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Allele
Tg(Rr233-lacZ)#Kwk | MGI:7330172
Name: transgene insertion, Kiyoshi Kawakami
Allele Type: Transgenic
Attribute String: Reporter
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Allele
Tg(Rr238-lacZ)#Shisa | MGI:7330087
Name: transgene insertion, Shigeru Sato
Allele Type: Transgenic
Attribute String: Reporter
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Allele
Tg(Rr234-lacZ)#Kwk | MGI:7330173
Name: transgene insertion, Kiyoshi Kawakami
Allele Type: Transgenic
Attribute String: Reporter
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Allele
Tg(Rr235-lacZ)#Kwk | MGI:7330174
Name: transgene insertion, Kiyoshi Kawakami
Allele Type: Transgenic
Attribute String: Reporter
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Allele
Tg(Rr236-lacZ)#Kwk | MGI:7330175
Name: transgene insertion, Kiyoshi Kawakami
Allele Type: Transgenic
Attribute String: Reporter
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Allele
Tg(Rr237-lacZ)#Kwk | MGI:7330176
Name: transgene insertion, Kiyoshi Kawakami
Allele Type: Transgenic
Attribute String: Reporter
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Allele
Tg(Rr239-lacZ)#Kwk | MGI:7330177
Name: transgene insertion, Kiyoshi Kawakami
Allele Type: Transgenic
Attribute String: Reporter
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Allele
Tg(Rr240-lacZ)#Kwk | MGI:7330178
Name: transgene insertion, Kiyoshi Kawakami
Allele Type: Transgenic
Attribute String: Reporter
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Allele
Tg(Rr238-lacZ)x4Shisa | MGI:7330088
Name: transgene insertion x4, Shigeru Sato
Allele Type: Transgenic
Attribute String: Reporter
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HT Experiment
GSE73866 | Transcriptional profiling of human and mouse nephron progenitor cells
 
Experiment Type: RNA-Seq
Study Type: Baseline
Source: GEO
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DO Term
DOID:0060232 | branchiootic syndrome
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Allele
Six1<tm1(cre)Xli> | MGI:5014213
Name: sine oculis-related homeobox 1; targeted mutation 1, Xue Li
Allele Type: Targeted
Attribute String: Recombinase
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Allele
Tg(Six1-cre)1Kwk | MGI:5698451
Name: transgene insertion 1, Kiyoshi Kawakami
Allele Type: Transgenic
Attribute String: Recombinase
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Genotype
Genotype
Symbol: Eya1/Eya1<+>
Background: Not Specified
Zygosity: ht
Has Mutant Allele: true
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HT Experiment
E-GEOD-30076 | Transcription profiling by array of mouse heart mutant for Ezh2
Series Id: GSE30076
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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Allele
Tg(Rr238*-lacZ)x4Shisa | MGI:7330089
Name: transgene insertion x4, Shigeru Sato
Allele Type: Transgenic
Attribute String: Reporter
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Allele
Tg(Rr232-lacZ)#Kwk | MGI:7330171
Name: transgene insertion, Kiyoshi Kawakami
Allele Type: Transgenic
Attribute String: Reporter
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Genotype
Genotype
Symbol: Six1/Six1<+>
Background: involves: 129
Zygosity: ht
Has Mutant Allele: true
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HT Experiment
E-GEOD-34274 | Gene expression profile of right ventricles from adult wild type and Ezh2-deficient hearts
Series Id: GSE34274
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: ArrayExpress
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Protein Domain
IPR028473 | EYA2
Type: Family
Description: Members of the eye absent (EYA) family were originally characterised in fly eye development. EYA proteins are both transcriptional activators and tyrosine phosphatases [, ], and have been shown to dephosphorylate H2AX, promoting repair and cell survival in the response to DNA damage []. EYA proteins (EYA1-4) are normally expressed early in development [, ]. Their phosphatase activity regulates Six1-Dach-Eya transcriptional effects in precursor cell proliferation and survival in mammalian organogenesis [].EYA2 plays an important role in hypaxial muscle development together with Six1 and Dach2; in this it is functionally redundant with EYA1 []. EYA2 is a necessary co-factor for many of the metastasis promoting functions of Six1 [].
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Publication
23435380 | -
First Author: Patrick AN
Year: 2013
Journal: Nat Struct Mol Biol
Title: Structure-function analyses of the human SIX1-EYA2 complex reveal insights into metastasis and BOR syndrome.
Volume: 20
Issue: 4
Pages: 447-53
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Protein Domain
IPR031701 | SIX1_SD
Type: Domain
Description: The SD domain is found N-terminal to the homeobox domain in the protein SIX1. As a transcription factor, SIX1 lacks intrinsic activation domains and thus needs to bind to the EYA family of co-factors in order to mediate transcriptional activation. The SD domain is necessary for this protein-protein interaction, binding to the C-terminal region of EYA (Eyes absent homologue proteins) [].
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Allele
Tg(Six1-cre)2Kwk | MGI:5700048
Name: transgene insertion 2, Kiyoshi Kawakami
Allele Type: Transgenic
Attribute String: Recombinase
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Allele
Tg(tetO-SIX1)#Hlf | MGI:5795965
Name: transgene insertion, Heide L Ford
Allele Type: Transgenic
Attribute String: Humanized sequence, Inducible, Inserted expressed sequence
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Genotype
Genotype
Symbol: Eya1/Eya1<+> Six2/Six2
Background: Not Specified
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Six1-cre)1Kwk/?
Background: involves: 129X1/SvJ
Zygosity: cn
Has Mutant Allele: true
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Protein Domain
IPR028479 | EYA3
Type: Family
Description: Members of the eye absent (EYA) family were originally characterised in fly eye development. EYA proteins are both transcriptional activators and tyrosine phosphatases [, ], and have been shown to dephosphorylate H2AX, promoting repair and cell survival in the response to DNA damage []. EYA proteins (EYA1-4) are normally expressed early in development [, ]. Their phosphatase activity regulates Six1-Dach-Eya transcriptional effects in precursor cell proliferation and survival in mammalian organogenesis [].EYA3 forms a complex with Six1 and Ski that regulates muscle terminal differentiation [].
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Genotype
Genotype
Symbol: Fgf8/Fgf8<+> Six1/Six1<+>
Background: involves: 129 * 129P2/OlaHsd * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Ctnnb1/Ctnnb1<+> Six1/Six1<+>
Background: involves: 129
Zygosity: cn
Has Mutant Allele: true
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Publication
9887327 | J:52368
First Author: Borsani G
Year: 1999
Journal: Hum Mol Genet
Title: EYA4, a novel vertebrate gene related to Drosophila eyes absent.
Volume: 8
Issue: 1
Pages: 11-23
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Publication
9020840 | J:38771
First Author: Abdelhak S
Year: 1997
Journal: Nat Genet
Title: A human homologue of the Drosophila eyes absent gene underlies branchio-oto-renal (BOR) syndrome and identifies a novel gene family.
Volume: 15
Issue: 2
Pages: 157-64
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Publication
19234442 | J:147286
First Author: Cook PJ
Year: 2009
Journal: Nature
Title: Tyrosine dephosphorylation of H2AX modulates apoptosis and survival decisions.
Volume: 458
Issue: 7238
Pages: 591-6
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Publication
17341163 | -
 
First Author: Jemc J
Year: 2007
Journal: Annu Rev Biochem
Title: The eyes absent family of phosphotyrosine phosphatases: properties and roles in developmental regulation of transcription.
Volume: 76
Pages: 513-38
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Protein
Q3TP96
Organism: Mus musculus/domesticus
Length: 286  
Fragment?: false
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Protein
A2A953
Organism: Mus musculus/domesticus
Length: 302  
Fragment?: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Six1/Six1<+>
Background: involves: 129/Sv * 129S4/SvJaeSor
Zygosity: cn
Has Mutant Allele: true
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Publication
25816987 | J:239288
First Author: Eisner A
Year: 2015
Journal: Dev Cell
Title: The Eya1 phosphatase promotes Shh signaling during hindbrain development and oncogenesis.
Volume: 33
Issue: 1
Pages: 22-35
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Publication
17540357 | J:122955
First Author: L'Honoré A
Year: 2007
Journal: Dev Biol
Title: Sequential expression and redundancy of Pitx2 and Pitx3 genes during muscle development.
Volume: 307
Issue: 2
Pages: 421-33
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Publication
29483821 | J:272082
First Author: Wang H
Year: 2018
Journal: Int J Biol Sci
Title: Disruption of Gen1 Causes Congenital Anomalies of the Kidney and Urinary Tract in Mice.
Volume: 14
Issue: 1
Pages: 10-20
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Six1-cre)2Kwk/?
Background: involves: 129S4/SvJaeSor * C57BL/6J * DBA/2J
Zygosity: cn
Has Mutant Allele: true
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