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Search results 1401 to 1500 out of 1514 for Ins1

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Type Details Score
GXD Expression
GXD Expression
Probe: MGI:5904269
Assay Type: Immunohistochemistry
Annotation Date: 2017-07-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3292520
Pattern: Single cells
Stage: TS20
Assay Id: MGI:5904279
Age: embryonic day 12.5
Image: 2 e12.5 bottom
Note: Expression is in beta cell progenitors.
Specimen Label: 2 e12.5 bottom
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
Probe: MGI:1343939
Assay Type: Immunohistochemistry
Annotation Date: 2001-09-26
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1706619
Pattern: Single cells
Stage: TS19
Assay Id: MGI:2150317
Age: embryonic day 11.5
Image: 11-day embryo
Note: Scattered, low-level expression of insulin was found in the epithelium.
Specimen Label: 11-day embryo
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:2152742
Assay Type: Immunohistochemistry
Annotation Date: 2001-11-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1706617
Pattern: Single cells
Stage: TS17
Assay Id: MGI:2152861
Age: embryonic day 10.5
Image: 5C
Note: Expression in only a few cells at the level of the initial dorsal evagination.
Specimen Label: 5C
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:2152742
Assay Type: Immunohistochemistry
Annotation Date: 2001-11-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1706617
Pattern: Single cells
Stage: TS17
Assay Id: MGI:2152861
Age: embryonic day 10.5
Image: 5D
Note: Expression in only a few cells in the dorsal pancreatic bud.
Specimen Label: 5D
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:2158661
Assay Type: Immunohistochemistry
Annotation Date: 2012-02-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1706615
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:5305999
Age: embryonic day 9.5
Image: 6G
Note: Expression is in the pancreatic primordium.
Specimen Label: 6G
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:2158661
Assay Type: Immunohistochemistry
Annotation Date: 2013-05-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1706619
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:5476729
Age: embryonic day 11.5
Specimen Label: 3B,D
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:5550061
Assay Type: Immunohistochemistry
Annotation Date: 2014-03-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1706618
Pattern: Single cells
Stage: TS18
Assay Id: MGI:5550100
Age: embryonic day 11.0
Image: 1E,G
Note: Few cells were immunopositive. An occasional immunopositive cell co-expressed Nestin.
Specimen Label: 1E,G
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:5614567
Assay Type: Immunohistochemistry
Annotation Date: 2015-02-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1706615
Pattern: Single cells
Stage: TS15
Assay Id: MGI:5614608
Age: embryonic day 9.5
Image: 4F
Note: Expression is easily detected in several cells in the epithelial lining of the cap-like dorsal anlage of the pancreas. Additional expression was occasionally seen in the wall of the ducts. It is not seen elsewhere in the embryo.
Specimen Label: 4F
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
 
Probe: MGI:6154251
Assay Type: Immunohistochemistry
Annotation Date: 2018-05-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1706617
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:6154263
Age: embryonic day 10.5
Note: Expression in alpha cells.
Specimen Label: 3A
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:6360987
Assay Type: Immunohistochemistry
Annotation Date: 2019-09-26
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1706617
Stage: TS17
Assay Id: MGI:6361010
Age: embryonic day 10.5
Specimen Label: E10.5 not shown
Detected: false
Specimen Num: 6
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GXD Expression
GXD Expression
     
Probe: MGI:6360987
Assay Type: Immunohistochemistry
Annotation Date: 2019-09-26
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1706619
Stage: TS19
Assay Id: MGI:6361010
Age: embryonic day 11.5
Specimen Label: E11.5 not shown
Detected: false
Specimen Num: 7
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GXD Expression
GXD Expression
 
Probe: MGI:6449768
Assay Type: Immunohistochemistry
Annotation Date: 2020-08-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1706617
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:6449808
Age: embryonic day 10.5
Image: 1A2
Specimen Label: 1A2
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:3767879
Assay Type: Immunohistochemistry
Annotation Date: 2008-01-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1751025
Pattern: Single cells
Stage: TS25
Assay Id: MGI:3767966
Age: embryonic day 17.5
Image: 6A
Note: Pancreatic duct co-expressing insulin and pancreatic polypeptide in epithelial cells; two cells contain both insulin and PP, two other cells within the same duct appear to contain one of these hormones.
Specimen Label: 6A
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6316644
Assay Type: Immunohistochemistry
Annotation Date: 2019-07-09
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1684126
Stage: TS26
Assay Id: MGI:6316654
Age: embryonic day 18.5
Image: 6A
Specimen Label: 6A
Detected: false
Specimen Num: 1
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Publication
- | J:15839
       
First Author: International Committee on Standardized Genetic Nomenclature for Mice
Year: 1993
Title: Nomenclature rule change to delete hyphens and parentheses from mouse locus symbols
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:4815
 
First Author: Glaser T
Year: 1985
Journal: Cytogenet Cell Genet
Title: A fine structure deletion map of chromosome 11p.
Volume: 40
Pages: 643 (Abstr.)
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Publication
- | J:4914
 
First Author: Lalley PA
Year: 1984
Journal: Cytogenet Cell Genet
Title: Mapping of mouse insulin genes (Abstracts of meeting presentations: Human gene mapping 7, Los Angeles Conference (1983) Seventh International Workshop on Human Gene Mapping)
Volume: 37 (1-4)
Pages: 515 (Abstr.) (399-616)
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Publication
25483876 | J:232607
First Author: Tamarina NA
Year: 2014
Journal: Islets
Title: Characterization of mice expressing Ins1 gene promoter driven CreERT recombinase for conditional gene deletion in pancreatic β-cells.
Volume: 6
Issue: 1
Pages: e27685
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Regulatory Region
MGI:7338989 | Rr267
Type: enhancer
Organism: mouse, laboratory
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Allele
Ins1<em3Smoc> | MGI:7264722
Name: insulin I; endonuclease-mediated mutation 3, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Regulatory Region
MGI:7338990 | Rr268
Type: enhancer
Organism: mouse, laboratory
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Publication
21335550 | -
First Author: Meur G
Year: 2011
Journal: J Biol Chem
Title: Nucleo-cytosolic shuttling of FoxO1 directly regulates mouse Ins2 but not Ins1 gene expression in pancreatic beta cells (MIN6).
Volume: 286
Issue: 15
Pages: 13647-56
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Allele
Tg(Ins1-cre/ERT2)16.7Ics | MGI:5500795
Name: transgene insertion 16.7, Mouse Clinical Institute
Allele Type: Transgenic
Attribute String: Inducible, Recombinase
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Allele
Ins1<em1(cre/ERT2)Smoc> | MGI:6724585
Name: insulin I; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Inducible, Recombinase
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Allele
Ins1<em2(icre)Smoc> | MGI:6724586
Name: insulin I; endonuclease-mediated mutation 2, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Recombinase
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Strain
MGI:6428997 | C57BL/6JSmoc-Ins1<em3Smoc>/Smoc
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Allele
Ins1<em2(cre/ERT2)Cya> | MGI:7657286
Name: insulin I; endonuclease-mediated mutation 2, Cyagen Biosciences
Allele Type: Endonuclease-mediated
Attribute String: Inducible, Recombinase
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Strain
MGI:6428996 | C57BL/6JSmoc-Ins1<em1(cre/ERT2)Smoc>/Smoc
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Strain
MGI:6475602 | C57BL/6JSmoc-Ins1<em2(icre)Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Allele
Rr266<em2Hino> | MGI:7338994
Name: regulatory region 266; endonuclease-mediated mutation 2, Hirofumi Noguchi
Allele Type: Endonuclease-mediated
Attribute String: Modified regulatory region
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Allele
Rr266<em3Hino> | MGI:7339001
Name: regulatory region 266; endonuclease-mediated mutation 3, Hirofumi Noguchi
Allele Type: Endonuclease-mediated
Attribute String: Modified regulatory region
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Allele
Rr266<em4Hino> | MGI:7339003
Name: regulatory region 266; endonuclease-mediated mutation 4, Hirofumi Noguchi
Allele Type: Endonuclease-mediated
Attribute String: Modified regulatory region
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Strain
MGI:7657667 | C57BL/6J-Ins1<em2(cre/ERT2)Cya>/Cya
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Strain
MGI:7381126 | B6N.Cg-Tg(Ins1-cre/ERT2)16.7Ics/Ics
Attribute String: congenic, mutant strain, transgenic
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Allele
Tg(Ins1-Igf1)1Fbos | MGI:7265012
Name: transgene insertion 1, Fatima Bosch
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(Ins1-IFNB1)28Fbos | MGI:7265048
Name: transgene insertion 28, Fatima Bosch
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(Ins1-IFNB1)56Fbos | MGI:7265049
Name: transgene insertion 56, Fatima Bosch
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Rr266<em1Hino> | MGI:7338992
Name: regulatory region 266; endonuclease-mediated mutation 1, Hirofumi Noguchi
Allele Type: Endonuclease-mediated
Attribute String: Modified regulatory region
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HT Experiment
GSE207498 | Pancreatic beta cell SERCA2 deficiency leads to impaired proinsulin processing and reduced ER to Golgi protein trafficking
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Publication
11994404 | J:76405
First Author: George M
Year: 2002
Journal: J Clin Invest
Title: Beta cell expression of IGF-I leads to recovery from type 1 diabetes.
Volume: 109
Issue: 9
Pages: 1153-63
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Publication
15085194 | J:89214
First Author: Ruberte J
Year: 2004
Journal: J Clin Invest
Title: Increased ocular levels of IGF-1 in transgenic mice lead to diabetes-like eye disease.
Volume: 113
Issue: 8
Pages: 1149-57
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Strain
MGI:7339111 | C57BL/6J-Rr266<em1Hino>
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Genotype
Genotype
Symbol: Rr266/Rr266
Background: C57BL/6J-Rr266
Zygosity: hm
Has Mutant Allele: true
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Allele
Tg(Ins1-luc)77Park | MGI:4417828
Name: transgene insertion 77, Soo-Young Park
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Publication
16108006 | J:155851
First Author: Park SY
Year: 2005
Journal: Genesis
Title: Optical imaging of pancreatic beta cells in living mice expressing a mouse insulin I promoter-firefly luciferase transgene.
Volume: 43
Issue: 2
Pages: 80-6
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Publication
23762423 | J:204244
First Author: Yin H
Year: 2013
Journal: PLoS One
Title: Enhancing pancreatic Beta-cell regeneration in vivo with pioglitazone and alogliptin.
Volume: 8
Issue: 6
Pages: e65777
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Publication
18949679 | J:155847
First Author: Park SY
Year: 2009
Journal: Horm Metab Res
Title: Noninvasive monitoring of changes in pancreatic beta-cell mass by bioluminescent imaging in MIP-luc transgenic mice.
Volume: 41
Issue: 1
Pages: 1-4
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Allele
Tg(Ins1-rtTA)#Caoy | MGI:6790391
Name: transgene insertion, Yanan Cao
Allele Type: Transgenic
Attribute String: Transactivator
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Publication
24770644 | J:208032
First Author: Hasegawa Y
Year: 2014
Journal: Exp Anim
Title: Generation and characterization of Ins1-cre-driver C57BL/6N for exclusive pancreatic beta cell-specific Cre-loxP recombination.
Volume: 63
Issue: 2
Pages: 183-91
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Allele
Tg(Ins1-cre)25Utr | MGI:5560759
Name: transgene insertion 25, Ken-ichi Yagami
Allele Type: Transgenic
Attribute String: Recombinase
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Allele
Tg(Ins1-cre,-DsRed*T3)#Caoy | MGI:6790389
Name: transgene insertion, Yanan Cao
Allele Type: Transgenic
Attribute String: Recombinase, Reporter
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Publication
9575186 | J:47674
First Author: Pelegrin M
Year: 1998
Journal: J Biol Chem
Title: Evidence from transgenic mice that interferon-beta may be involved in the onset of diabetes mellitus.
Volume: 273
Issue: 20
Pages: 12332-40
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Publication
23099863 | J:208607
First Author: Anguela XM
Year: 2013
Journal: Diabetes
Title: Nonviral-mediated hepatic expression of IGF-I increases Treg levels and suppresses autoimmune diabetes in mice.
Volume: 62
Issue: 2
Pages: 551-60
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Strain
MGI:7339119 | C57BL/6J-Rr266<em1Hino> Rr268<em1Hino>
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Genotype
Genotype
Symbol: Rr266/Rr266 Rr268/Rr268
Background: C57BL/6J-Rr266 Rr268
Zygosity: cx
Has Mutant Allele: true
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Publication
25198535 | J:221524
First Author: Patel M
Year: 2014
Journal: PLoS One
Title: Non-invasive bioluminescence imaging of β-cell function in obese-hyperglycemic [ob/ob] mice.
Volume: 9
Issue: 9
Pages: e106693
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Publication
15557158 | J:94366
First Author: Alba A
Year: 2004
Journal: J Immunol
Title: IFN beta accelerates autoimmune type 1 diabetes in nonobese diabetic mice and breaks the tolerance to beta cells in nondiabetes-prone mice.
Volume: 173
Issue: 11
Pages: 6667-75
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Publication
25497096 | J:222657
First Author: Piccand J
Year: 2014
Journal: Cell Rep
Title: Rfx6 maintains the functional identity of adult pancreatic β cells.
Volume: 9
Issue: 6
Pages: 2219-32
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Publication
- | J:199064
     
First Author: Pavlovic G
Year: 2013
Journal: MGI Direct Data Submission
Title: Data submissions from the Mouse Clinical Institute (ICS)
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Strain
MGI:6145639 | C57BL/6N-Tg(Ins1-cre)25Utr/Rbrc
Attribute String: mutant strain, coisogenic, transgenic
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Publication
17130467 | J:121004
First Author: Casellas A
Year: 2006
Journal: Diabetes
Title: Expression of IGF-I in pancreatic islets prevents lymphocytic infiltration and protects mice from type 1 diabetes.
Volume: 55
Issue: 12
Pages: 3246-55
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Publication
19656489 | J:151308
First Author: Gauthier BR
Year: 2009
Journal: Cell Metab
Title: PDX1 deficiency causes mitochondrial dysfunction and defective insulin secretion through TFAM suppression.
Volume: 10
Issue: 2
Pages: 110-8
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Publication
19380737 | J:148327
First Author: Zhang SS
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Coordinated regulation by Shp2 tyrosine phosphatase of signaling events controlling insulin biosynthesis in pancreatic beta-cells.
Volume: 106
Issue: 18
Pages: 7531-6
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Publication
19560418 | J:150410
First Author: Dougherty MK
Year: 2009
Journal: Mol Cell
Title: KSR2 is a calcineurin substrate that promotes ERK cascade activation in response to calcium signals.
Volume: 34
Issue: 6
Pages: 652-62
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Publication
20374962 | J:159614
First Author: Gu C
Year: 2010
Journal: Cell Metab
Title: Pancreatic beta cells require NeuroD to achieve and maintain functional maturity.
Volume: 11
Issue: 4
Pages: 298-310
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Publication
24583012 | J:208142
First Author: Kuang J
Year: 2014
Journal: FEBS Lett
Title: Identification of insulin as a novel retinoic acid receptor-related orphan receptor α target gene.
Volume: 588
Issue: 6
Pages: 1071-9
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Publication
29605295 | J:270542
First Author: Matsuzawa T
Year: 2018
Journal: Biochem Biophys Res Commun
Title: Heparan sulfate in pancreatic β-cells contributes to normal glucose homeostasis by regulating insulin secretion.
Volume: 499
Issue: 3
Pages: 688-695
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Publication
37557182 | J:338980
   
First Author: Sekiya M
Year: 2023
Journal: Cell Rep
Title: Loss of CtBP2 may be a mechanistic link between metabolic derangements and progressive impairment of pancreatic β cell function.
Pages: 112914
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Allele
Tg(Ins1-itTA)#Fto | MGI:5810641
Name: transgene insertion, Francois Tronche
Allele Type: Transgenic
Attribute String: Transactivator
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Genotype
Genotype
Symbol: Tg(Ins1-cre,-DsRed*T3)#Caoy/?
Background: involves: C57BL/6J
Zygosity: ot
Has Mutant Allele: true
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Publication
22628617 | J:186560
First Author: Wang CY
Year: 2012
Journal: J Lipid Res
Title: Tsc2, a positional candidate gene underlying a quantitative trait locus for hepatic steatosis.
Volume: 53
Issue: 8
Pages: 1493-501
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Publication
17620420 | J:126569
First Author: Jarchum I
Year: 2007
Journal: Diabetes
Title: In vivo cytotoxicity of insulin-specific CD8+ T-cells in HLA-A*0201 transgenic NOD mice.
Volume: 56
Issue: 10
Pages: 2551-60
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Publication
21346176 | J:171756
First Author: Niens M
Year: 2011
Journal: Diabetes
Title: Prevention of "Humanized" diabetogenic CD8 T-cell responses in HLA-transgenic NOD mice by a multipeptide coupled-cell approach.
Volume: 60
Issue: 4
Pages: 1229-36
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Publication
19880509 | J:158307
First Author: Hodish I
Year: 2010
Journal: J Biol Chem
Title: Misfolded proinsulin affects bystander proinsulin in neonatal diabetes.
Volume: 285
Issue: 1
Pages: 685-94
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•
•
Publication
22566534 | J:203172
First Author: Okamoto K
Year: 2012
Journal: Diabetes
Title: Inhibition of glucose-stimulated insulin secretion by KCNJ15, a newly identified susceptibility gene for type 2 diabetes.
Volume: 61
Issue: 7
Pages: 1734-41
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Publication
20858756 | J:172332
First Author: Geng X
Year: 2011
Journal: Am J Physiol Endocrinol Metab
Title: α-Synuclein binds the K(ATP) channel at insulin-secretory granules and inhibits insulin secretion.
Volume: 300
Issue: 2
Pages: E276-86
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•
Publication
19358156 | J:149908
First Author: Scott GJ
Year: 2009
Journal: Genesis
Title: Abnormal glucose metabolism in heterozygous mutant mice for a type I receptor required for BMP signaling.
Volume: 47
Issue: 6
Pages: 385-91
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•
•
•
•
Publication
27329800 | J:241413
First Author: Mehta ZB
Year: 2016
Journal: Am J Physiol Endocrinol Metab
Title: Changes in the expression of the type 2 diabetes-associated gene VPS13C in the β-cell are associated with glucose intolerance in humans and mice.
Volume: 311
Issue: 2
Pages: E488-507
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•
•
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Publication
25355422 | J:219225
First Author: Mitchell RK
Year: 2015
Journal: Hum Mol Genet
Title: Selective disruption of Tcf7l2 in the pancreatic β cell impairs secretory function and lowers β cell mass.
Volume: 24
Issue: 5
Pages: 1390-9
•
•
•
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Publication
26647386 | J:252954
First Author: Zhu S
Year: 2016
Journal: Diabetes
Title: Monitoring C-Peptide Storage and Secretion in Islet β-Cells In Vitro and In Vivo.
Volume: 65
Issue: 3
Pages: 699-709
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•
•
•
•
Publication
19264802 | J:173035
First Author: Yang Y
Year: 2009
Journal: Nucleic Acids Res
Title: The Krüppel-like zinc finger protein Glis3 directly and indirectly activates insulin gene transcription.
Volume: 37
Issue: 8
Pages: 2529-38
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Publication
20501672 | J:162929
First Author: Chen TS
Year: 2010
Journal: Endocrinology
Title: Delineating biological pathways unique to embryonic stem cell-derived insulin-producing cell lines from their noninsulin-producing progenitor cell lines.
Volume: 151
Issue: 8
Pages: 3600-10
•
•
•
•
•
Publication
32003437 | J:286252
First Author: Cerqueira FM
Year: 2020
Journal: Biochem J
Title: MitoTimer-based high-content screen identifies two chemically-related benzothiophene derivatives that enhance basal mitophagy.
Volume: 477
Issue: 2
Pages: 461-475
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•
•
•
•
Publication
33784258 | J:312144
 
First Author: Mishra A
Year: 2021
Journal: JCI Insight
Title: Perilipin 2 downregulation in β cells impairs insulin secretion under nutritional stress and damages mitochondria.
Volume: 6
Issue: 9
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•
•
•
•
Publication
26824049 | J:339768
 
First Author: Babad J
Year: 2016
Journal: J Diabetes Res
Title: An HLA-Transgenic Mouse Model of Type 1 Diabetes That Incorporates the Reduced but Not Abolished Thymic Insulin Expression Seen in Patients.
Volume: 2016
Pages: 7959060
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Strain
MGI:5574336 | B6.Cg-Gt(ROSA)26Sor<tm1Sor> Tg(Ins1-cre)25Utr
Attribute String: congenic, targeted mutation, transgenic
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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