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Search results 1901 to 2000 out of 2018 for Sparc

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0.019s

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Type Details Score
Publication
15375558 | -
First Author: Isler SG
Year: 2004
Journal: Int J Oncol
Title: Evidence for transcriptional repression of SPARC-like 1, a gene downregulated in human lung tumors.
Volume: 25
Issue: 4
Pages: 1073-9
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Publication
28010899 | -
 
First Author: Gagliardi F
Year: 2017
Journal: Crit Rev Oncol Hematol
Title: SPARCL1 a novel player in cancer biology.
Volume: 109
Pages: 63-68
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Protein Domain
IPR016359 | SPARC-like_p1
Type: Family
Description: This group represents a SPARC-like (Secreted Protein Acidic and Rich in Cysteine) protein 1 (SPARCL1; also known as Hevin). SPARCL1 is a secreted glycoprotein, belonging to SPARC family of matricellular proteins []. SPARCL1 is downregulated in various tumours and may have a tumor-suppressor function [, ].
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Publication
38553636 | J:346632
First Author: Li H
Year: 2024
Journal: Commun Biol
Title: Segregation of morphogenetic regulatory function of Shox2 from its cell fate guardian role in sinoatrial node development.
Volume: 7
Issue: 1
Pages: 385
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Publication
19144404 | -
First Author: Kamioka M
Year: 2009
Journal: Leuk Res
Title: Testican 3 expression in adult T-cell leukemia.
Volume: 33
Issue: 7
Pages: 913-8
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Protein Domain
IPR019577 | SPARC/Testican_Ca-bd-dom
Type: Domain
Description: This entry represents the calcium-binding domain found in SPARC (Secreted Protein Acidic and Rich in Cysteine) and Testican (also known as SPOCK; or SParc/Osteonectin, Cwcv and Kazal-like domains) proteins. SPARC proteins are down-regulated in various tumours and may have a tumour-suppressor function [, ]. Testican-3 appears to be a novel regulator that reduces the activity of matrix metalloproteinase (MMP) in adult T-cell leukemia (ATL) [].This cysteine-rich domain is responsible for the anti-spreading activity of human urothelial cells. This extracellular calcium-binding domain is rich in α-helices and contains two EF-hands that each coordinates one Ca2+ ion, forming a helix-loop-helix structure that not only drives the conformation of the protein but is also necessary for biological activity. The anti-spreading activity was dependent on the coordination of Ca2+ by a Glu residue at the Z position of EF-hand 2 [].
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Publication
17325739 | -
First Author: Esposito I
Year: 2007
Journal: Neoplasia
Title: Tumor-suppressor function of SPARC-like protein 1/Hevin in pancreatic cancer.
Volume: 9
Issue: 1
Pages: 8-17
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Publication
35483741 | J:324527
First Author: Matoba S
Year: 2022
Journal: Genes Dev
Title: Noncanonical imprinting sustains embryonic development and restrains placental overgrowth.
Volume: 36
Issue: 7-8
Pages: 483-494
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Publication
31320323 | J:293668
 
First Author: Li H
Year: 2019
Journal: Development
Title: Nkx2-5 defines a subpopulation of pacemaker cells and is essential for the physiological function of the sinoatrial node in mice.
Volume: 146
Issue: 14
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Publication
31397024 | J:279273
First Author: Chen G
Year: 2019
Journal: Dev Dyn
Title: Regional difference in microRNA regulation in the skull vault.
Volume: 248
Issue: 10
Pages: 1009-1019
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Publication
31284824 | J:306155
First Author: Goodyer WR
Year: 2019
Journal: Circ Res
Title: Transcriptomic Profiling of the Developing Cardiac Conduction System at Single-Cell Resolution.
Volume: 125
Issue: 4
Pages: 379-397
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Genotype
Genotype
Symbol: Del(11Nmur2-Sparc)2Anjm/+ Del(11Sparc-Gpx3)91Anjm/+
Background: involves: 129P2/OlaHsd * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Publication
19842175 | J:153731
First Author: Pazin DE
Year: 2009
Journal: Dev Dyn
Title: Developmental expression of Smoc1 and Smoc2 suggests potential roles in fetal gonad and reproductive tract differentiation.
Volume: 238
Issue: 11
Pages: 2877-90
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Publication
39636726 | J:359797
First Author: Coren L
Year: 2024
Journal: Cell Rep
Title: Fibroblast diversification is an embryonic process dependent on muscle contraction.
Volume: 43
Issue: 12
Pages: 115034
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Publication
23516636 | J:225061
First Author: Kouskoura T
Year: 2013
Journal: PLoS One
Title: The etiology of cleft palate formation in BMP7-deficient mice.
Volume: 8
Issue: 3
Pages: e59463
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Publication
30953627 | J:276573
First Author: Wiegering A
Year: 2019
Journal: Dev Biol
Title: GLI3 repressor but not GLI3 activator is essential for mouse eye patterning and morphogenesis.
Volume: 450
Issue: 2
Pages: 141-154
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Publication
36542062 | J:332217
   
First Author: Feng J
Year: 2022
Journal: Elife
Title: TGF-β signaling and Creb5 cooperatively regulate Fgf18 to control pharyngeal muscle development.
Volume: 11
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Publication
35951416 | J:330742
 
First Author: Goodyer WR
Year: 2022
Journal: J Clin Invest
Title: In vivo visualization and molecular targeting of the cardiac conduction system.
Volume: 132
Issue: 20
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Publication
23531410 | J:355913
 
First Author: Laugel-Haushalter V
Year: 2013
Journal: BMC Res Notes
Title: Molars and incisors: show your microarray IDs.
Volume: 6
Pages: 113
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Publication
35196485 | J:337684
First Author: Xie Y
Year: 2022
Journal: Cell Rep
Title: Astrocyte-neuron crosstalk through Hedgehog signaling mediates cortical synapse development.
Volume: 38
Issue: 8
Pages: 110416
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Publication
20018883 | J:159752
First Author: Weaver MS
Year: 2010
Journal: J Biol Chem
Title: Processing of the matricellular protein hevin in mouse brain is dependent on ADAMTS4.
Volume: 285
Issue: 8
Pages: 5868-77
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Publication
14715135 | J:87426
First Author: Gongidi V
Year: 2004
Journal: Neuron
Title: SPARC-like 1 regulates the terminal phase of radial glia-guided migration in the cerebral cortex.
Volume: 41
Issue: 1
Pages: 57-69
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Publication
17961514 | J:128446
First Author: Ishigaki N
Year: 2007
Journal: Biochem Biophys Res Commun
Title: Involvement of glomerular SREBP-1c in diabetic nephropathy.
Volume: 364
Issue: 3
Pages: 502-8
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Publication
8276417 | J:15125
First Author: Jabs EW
Year: 1993
Journal: Genomics
Title: Genetic and physical mapping of the Treacher Collins syndrome locus with respect to loci in the chromosome 5q3 region.
Volume: 18
Issue: 1
Pages: 7-13
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Publication
32541007 | J:295217
 
First Author: Drake KA
Year: 2020
Journal: Development
Title: Stromal β-catenin activation impacts nephron progenitor differentiation in the developing kidney and may contribute to Wilms tumor.
Volume: 147
Issue: 21
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Publication
32586976 | J:296650
 
First Author: England AR
Year: 2020
Journal: Development
Title: Identification and characterization of cellular heterogeneity within the developing renal interstitium.
Volume: 147
Issue: 15
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Publication
33898467 | J:306327
 
First Author: Xu J
Year: 2021
Journal: Front Cell Dev Biol
Title: Cis-Repression of Foxq1 Expression Affects Foxf2-Mediated Gene Expression in Palate Development.
Volume: 9
Pages: 665109
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Publication
34822715 | J:316178
 
First Author: Gamart J
Year: 2021
Journal: Development
Title: SMAD4 target genes are part of a transcriptional network that integrates the response to BMP and SHH signaling during early limb bud patterning.
Volume: 148
Issue: 23
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Publication
28439006 | J:242224
First Author: Haller M
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Murine model indicates 22q11.2 signaling adaptor CRKL is a dosage-sensitive regulator of genitourinary development.
Volume: 114
Issue: 19
Pages: 4981-4986
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Publication
17150988 | J:117793
First Author: Kudo LC
Year: 2007
Journal: Cereb Cortex
Title: Genetic analysis of anterior posterior expression gradients in the developing mammalian forebrain.
Volume: 17
Issue: 9
Pages: 2108-22
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Publication
32040930 | J:287549
First Author: Xu J
Year: 2020
Journal: J Dent Res
Title: Genome-wide Identification of Foxf2 Target Genes in Palate Development.
Volume: 99
Issue: 4
Pages: 463-471
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Publication
11668390 | J:72512
First Author: Choi JD
Year: 2001
Journal: Mamm Genome
Title: Microarray expression profiling of tissues from mice with uniparental duplications of chromosomes 7 and 11 to identify imprinted genes.
Volume: 12
Issue: 10
Pages: 758-64
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Publication
15998744 | J:103688
First Author: Challen G
Year: 2005
Journal: Physiol Genomics
Title: Temporal and spatial transcriptional programs in murine kidney development.
Volume: 23
Issue: 2
Pages: 159-71
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Publication
17586095 | J:123553
First Author: Bykov I
Year: 2007
Journal: Clin Immunol
Title: Effect of chronic ethanol consumption on the expression of complement components and acute-phase proteins in liver.
Volume: 124
Issue: 2
Pages: 213-20
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Publication
34493647 | J:310227
 
First Author: Mathes S
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: FGF-2-dependent signaling activated in aged human skeletal muscle promotes intramuscular adipogenesis.
Volume: 118
Issue: 37
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Publication
33534863 | J:301579
First Author: Jones CE
Year: 2021
Journal: PLoS One
Title: Pten regulates collagen fibrillogenesis by fibroblasts through SPARC.
Volume: 16
Issue: 2
Pages: e0245653
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Publication
28821665 | J:247547
First Author: Morel L
Year: 2017
Journal: J Neurosci
Title: Molecular and Functional Properties of Regional Astrocytes in the Adult Brain.
Volume: 37
Issue: 36
Pages: 8706-8717
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Publication
26731484 | J:233155
First Author: Galimov A
Year: 2016
Journal: Stem Cells
Title: MicroRNA-29a in Adult Muscle Stem Cells Controls Skeletal Muscle Regeneration During Injury and Exercise Downstream of Fibroblast Growth Factor-2.
Volume: 34
Issue: 3
Pages: 768-80
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Publication
27105498 | J:310175
First Author: Riabov V
Year: 2016
Journal: Oncotarget
Title: Stabilin-1 is expressed in human breast cancer and supports tumor growth in mammary adenocarcinoma mouse model.
Volume: 7
Issue: 21
Pages: 31097-110
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Publication
28439016 | J:256704
First Author: Sakers K
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Astrocytes locally translate transcripts in their peripheral processes.
Volume: 114
Issue: 19
Pages: E3830-E3838
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Publication
2838412 | J:9229
First Author: Swaroop A
Year: 1988
Journal: Genomics
Title: Molecular analysis of the cDNA for human SPARC/osteonectin/BM-40: sequence, expression, and localization of the gene to chromosome 5q31-q33.
Volume: 2
Issue: 1
Pages: 37-47
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Publication
8105479 | J:33944
First Author: Boylan JF
Year: 1993
Journal: Proc Natl Acad Sci U S A
Title: Loss of retinoic acid receptor gamma function in F9 cells by gene disruption results in aberrant Hoxa-1 expression and differentiation upon retinoic acid treatment.
Volume: 90
Issue: 20
Pages: 9601-5
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Publication
8020966 | J:17404
First Author: Witzgall R
Year: 1994
Journal: Genomics
Title: Genomic structure and chromosomal location of the rat gene encoding the zinc finger transcription factor Kid-1.
Volume: 20
Issue: 2
Pages: 203-9
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Publication
9065824 | J:40415
First Author: Mashimo J
Year: 1997
Journal: Cancer Lett
Title: Decrease in the expression of a novel TGF beta1-inducible and ras-recision gene, TSC-36, in human cancer cells.
Volume: 113
Issue: 1-2
Pages: 213-9
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Publication
9154819 | J:40337
First Author: Mettouchi A
Year: 1997
Journal: Mol Cell Biol
Title: The c-Jun-induced transformation process involves complex regulation of tenascin-C expression.
Volume: 17
Issue: 6
Pages: 3202-9
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Publication
16616109 | J:114912
First Author: Kang HM
Year: 2006
Journal: Cancer Genet Cytogenet
Title: DNA copy number alterations and expression of relevant genes in mouse thymic lymphomas induced by gamma-irradiation and N-methyl-N-nitrosourea.
Volume: 166
Issue: 1
Pages: 27-35
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Publication
22457777 | J:356962
First Author: Liddelow SA
Year: 2012
Journal: PLoS One
Title: Molecular characterisation of transport mechanisms at the developing mouse blood-CSF interface: a transcriptome approach.
Volume: 7
Issue: 3
Pages: e33554
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Publication
30658191 | J:295166
 
First Author: Nahon JE
Year: 2019
Journal: Atherosclerosis
Title: Hematopoietic Stabilin-1 deficiency does not influence atherosclerosis susceptibility in LDL receptor knockout mice.
Volume: 281
Pages: 47-55
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Publication
19223608 | J:356531
First Author: Marotta M
Year: 2009
Journal: Physiol Genomics
Title: Muscle genome-wide expression profiling during disease evolution in mdx mice.
Volume: 37
Issue: 2
Pages: 119-32
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Protein
P70663
Organism: Mus musculus/domesticus
Length: 650  
Fragment?: false
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Protein
Q3UYK7
Organism: Mus musculus/domesticus
Length: 650  
Fragment?: false
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Protein
Q3TYD5
Organism: Mus musculus/domesticus
Length: 650  
Fragment?: false
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Publication
36960826 | J:334527
 
First Author: Weiss AC
Year: 2023
Journal: Development
Title: Permissive ureter specification by TBX18-mediated repression of metanephric gene expression.
Volume: 150
Issue: 6
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Publication
16966370 | J:114669
First Author: Takeda K
Year: 2006
Journal: Mol Cell Biol
Title: Placental but not heart defects are associated with elevated hypoxia-inducible factor alpha levels in mice lacking prolyl hydroxylase domain protein 2.
Volume: 26
Issue: 22
Pages: 8336-46
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Publication
35974052 | J:327415
First Author: Jing J
Year: 2022
Journal: Nat Commun
Title: Spatiotemporal single-cell regulatory atlas reveals neural crest lineage diversification and cellular function during tooth morphogenesis.
Volume: 13
Issue: 1
Pages: 4803
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Publication
26100917 | J:226941
First Author: Akerberg BN
Year: 2015
Journal: Dev Biol
Title: Endocardial Brg1 disruption illustrates the developmental origins of semilunar valve disease.
Volume: 407
Issue: 1
Pages: 158-72
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Publication
35918150 | J:330505
     
First Author: Drake KA
Year: 2022
Journal: J Am Soc Nephrol
Title: Transcription Factors YAP/TAZ and SRF Cooperate To Specify Renal Myofibroblasts in the Developing Mouse Kidney.
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Publication
30936179 | J:274879
 
First Author: van Eif VWW
Year: 2019
Journal: Development
Title: Transcriptome analysis of mouse and human sinoatrial node cells reveals a conserved genetic program.
Volume: 146
Issue: 8
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Publication
21986284 | J:189458
First Author: Kandalam V
Year: 2011
Journal: Circulation
Title: Lack of tissue inhibitor of metalloproteinases 2 leads to exacerbated left ventricular dysfunction and adverse extracellular matrix remodeling in response to biomechanical stress.
Volume: 124
Issue: 19
Pages: 2094-105
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Publication
39848964 | J:361521
First Author: Morrey JD
Year: 2025
Journal: Sci Rep
Title: Identification of candidate genes involved in Zika virus-induced reversible paralysis of mice.
Volume: 15
Issue: 1
Pages: 2926
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Publication
21220554 | J:171539
First Author: Kang MH
Year: 2011
Journal: Invest Ophthalmol Vis Sci
Title: Effect of hevin deletion in mice and characterization in trabecular meshwork.
Volume: 52
Issue: 5
Pages: 2187-93
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Publication
36028175 | J:328546
     
First Author: Yamamoto K
Year: 2022
Journal: Matrix Biol
Title: A top-down approach to uncover the hidden ligandome of low-density lipoprotein receptor-related protein 1 in cartilage.
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Publication
10233163 | J:55346
First Author: Bradshaw AD
Year: 1999
Journal: Mol Biol Cell
Title: Primary mesenchymal cells isolated from SPARC-null mice exhibit altered morphology and rates of proliferation.
Volume: 10
Issue: 5
Pages: 1569-79
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Publication
17956346 | J:131229
First Author: Clarke AR
Year: 2007
Journal: Biochem Soc Trans
Title: Cancer genetics: mouse models of intestinal cancer.
Volume: 35
Issue: Pt 5
Pages: 1338-41
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Protein
A0A286YCI6
Organism: Mus musculus/domesticus
Length: 343  
Fragment?: false
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Protein
A0A087WPP6
Organism: Mus musculus/domesticus
Length: 367  
Fragment?: false
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Protein
Q8BM19
Organism: Mus musculus/domesticus
Length: 367  
Fragment?: false
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Protein
Q3US75
Organism: Mus musculus/domesticus
Length: 226  
Fragment?: true
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Protein
Q6PAN0
Organism: Mus musculus/domesticus
Length: 321  
Fragment?: false
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Protein
Q8BM07
Organism: Mus musculus/domesticus
Length: 364  
Fragment?: false
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Publication
- | J:11966
 
First Author: Womack JE
Year: 1989
Journal: Cytogenet Cell Genet
Title: Syntenic mapping of 37 loci in cattle. Chromosomal conservation with mouse and man.
Volume: 51
Pages: 1109 (Abstr.)
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Protein
Q8BKV0
Organism: Mus musculus/domesticus
Length: 436  
Fragment?: false
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Protein
Q9ER58
Organism: Mus musculus/domesticus
Length: 423  
Fragment?: false
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Protein
Q62288
Organism: Mus musculus/domesticus
Length: 442  
Fragment?: false
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Protein
Q571A9
Organism: Mus musculus/domesticus
Length: 488  
Fragment?: true
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Protein
F6SLR4
Organism: Mus musculus/domesticus
Length: 423  
Fragment?: false
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Protein
B2RXY1
Organism: Mus musculus/domesticus
Length: 441  
Fragment?: false
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Protein
Q80U51
Organism: Mus musculus/domesticus
Length: 380  
Fragment?: true
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Protein
Q8BKQ3
Organism: Mus musculus/domesticus
Length: 439  
Fragment?: false
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Protein
Q6DIC9
Organism: Mus musculus/domesticus
Length: 442  
Fragment?: false
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Publication
34108685 | J:324116
First Author: Morita R
Year: 2021
Journal: Nature
Title: Tracing the origin of hair follicle stem cells.
Volume: 594
Issue: 7864
Pages: 547-552
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Publication
34248495 | J:308708
 
First Author: Martinez ME
Year: 2021
Journal: Front Neurosci
Title: The Type 3 Deiodinase Is a Critical Modulator of Thyroid Hormone Sensitivity in the Fetal Brain.
Volume: 15
Pages: 703730
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Publication
26671461 | J:228726
First Author: Golonzhka O
Year: 2015
Journal: Neuron
Title: Pbx Regulates Patterning of the Cerebral Cortex in Progenitors and Postmitotic Neurons.
Volume: 88
Issue: 6
Pages: 1192-207
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Publication
34003106 | J:307862
   
First Author: Wilkerson BA
Year: 2021
Journal: Elife
Title: Novel cell types and developmental lineages revealed by single-cell RNA-seq analysis of the mouse crista ampullaris.
Volume: 10
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Publication
16964442 | J:112870
First Author: Mager J
Year: 2006
Journal: Mamm Genome
Title: Identification of candidate maternal-effect genes through comparison of multiple microarray data sets.
Volume: 17
Issue: 9
Pages: 941-9
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Publication
19884258 | J:154029
First Author: Munger SC
Year: 2009
Journal: Genes Dev
Title: Elucidation of the transcription network governing mammalian sex determination by exploiting strain-specific susceptibility to sex reversal.
Volume: 23
Issue: 21
Pages: 2521-36
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Publication
32747435 | J:295894
 
First Author: Wei G
Year: 2020
Journal: Development
Title: Erk and MAPK signaling is essential for intestinal development through Wnt pathway modulation.
Volume: 147
Issue: 17
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Protein
Q8CD91
Organism: Mus musculus/domesticus
Length: 447  
Fragment?: false
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Protein
Q8BLY1
Organism: Mus musculus/domesticus
Length: 463  
Fragment?: false
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Protein
Q3TVR8
Organism: Mus musculus/domesticus
Length: 446  
Fragment?: false
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Protein
E9QKW2
Organism: Mus musculus/domesticus
Length: 452  
Fragment?: false
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Protein
D3Z3A3
Organism: Mus musculus/domesticus
Length: 434  
Fragment?: false
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Protein
A0A3B2WCK7
Organism: Mus musculus/domesticus
Length: 458  
Fragment?: false
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Protein
A0A0R4J1E4
Organism: Mus musculus/domesticus
Length: 463  
Fragment?: false
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Publication
21491433 | J:174459
First Author: Boyle MP
Year: 2011
Journal: J Comp Neurol
Title: Cell-type-specific consequences of Reelin deficiency in the mouse neocortex, hippocampus, and amygdala.
Volume: 519
Issue: 11
Pages: 2061-89
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Publication
38923264 | J:360305
First Author: Zhu Z
Year: 2024
Journal: Adv Sci (Weinh)
Title: Isl Identifies the Extraembryonic Mesodermal/Allantois Progenitors and is Required for Placenta Morphogenesis and Vasculature Formation.
Volume: 11
Issue: 32
Pages: e2400238
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Publication
26930384 | J:231595
First Author: Gurdziel K
Year: 2016
Journal: Dev Dyn
Title: Transcriptome of the inner circular smooth muscle of the developing mouse intestine: Evidence for regulation of visceral smooth muscle genes by the hedgehog target gene, cJun.
Volume: 245
Issue: 5
Pages: 614-26
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Publication
26238476 | J:226028
First Author: Lewandowski JP
Year: 2015
Journal: Dev Biol
Title: Spatiotemporal regulation of GLI target genes in the mammalian limb bud.
Volume: 406
Issue: 1
Pages: 92-103
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Publication
19906978 | J:154739
First Author: Quina LA
Year: 2009
Journal: J Neurosci
Title: Brn3a and Nurr1 mediate a gene regulatory pathway for habenula development.
Volume: 29
Issue: 45
Pages: 14309-22
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Publication
19334288 | J:148410
First Author: Combes AN
Year: 2009
Journal: Dev Dyn
Title: Three-dimensional visualization of testis cord morphogenesis, a novel tubulogenic mechanism in development.
Volume: 238
Issue: 5
Pages: 1033-41
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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