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Search results 201 to 249 out of 249 for Atg3

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Type Details Score
Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Protein
Q9CPX6
Organism: Mus musculus/domesticus
Length: 314  
Fragment?: false
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UniProt Feature
UniProt Feature
Begin: 1
Description: Ubiquitin-like-conjugating enzyme ATG3
Type: chain
End: 314
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Publication
33446636 | J:300900
First Author: Ye Y
Year: 2021
Journal: Nat Commun
Title: An N-terminal conserved region in human Atg3 couples membrane curvature sensitivity to conjugase activity during autophagy.
Volume: 12
Issue: 1
Pages: 374
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Publication
11825910 | -
First Author: Tanida I
Year: 2002
Journal: J Biol Chem
Title: Human Apg3p/Aut1p homologue is an authentic E2 enzyme for multiple substrates, GATE-16, GABARAP, and MAP-LC3, and facilitates the conjugation of hApg12p to hApg5p.
Volume: 277
Issue: 16
Pages: 13739-44
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Publication
22024753 | -
First Author: Moloughney JG
Year: 2011
Journal: Autophagy
Title: Vaccinia virus leads to ATG12–ATG3 conjugation and deficiency in autophagosome formation.
Volume: 7
Issue: 12
Pages: 1434-47
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Interaction Experiment
Radoshevich L (2010)
Description: ATG12 conjugation to ATG3 regulates mitochondrial homeostasis and cell death.
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Interaction Experiment
Metlagel Z (2013)
Description: Structural basis of ATG3 recognition by the autophagic ubiquitin-like protein ATG12.
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Publication
23142983 | -
First Author: Yamaguchi M
Year: 2012
Journal: Nat Struct Mol Biol
Title: Noncanonical recognition and UBL loading of distinct E2s by autophagy-essential Atg7.
Volume: 19
Issue: 12
Pages: 1250-6
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Protein Domain
IPR032197 | Atg7_N
Type: Domain
Description: This is the N-terminal domain of ubiquitin-like modifier-activating enzyme ATG7. In Arabidopsis this domain binds the E2 enzymes ATG10 and ATG3 [].
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Protein
S4R1U3
Organism: Mus musculus/domesticus
Length: 67  
Fragment?: true
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Protein
S4R1K1
Organism: Mus musculus/domesticus
Length: 41  
Fragment?: true
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Protein
S4R1W9
Organism: Mus musculus/domesticus
Length: 110  
Fragment?: true
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Protein
Q8R1P4
Organism: Mus musculus/domesticus
Length: 215  
Fragment?: false
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Protein
A0A0R4J029
Organism: Mus musculus/domesticus
Length: 211  
Fragment?: false
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Publication
18398292 | -
First Author: Noda T
Year: 2008
Journal: Autophagy
Title: The Ubi brothers reunited.
Volume: 4
Issue: 4
Pages: 540-1
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Publication
17227760 | -
First Author: Yamada Y
Year: 2007
Journal: J Biol Chem
Title: The crystal structure of Atg3, an autophagy-related ubiquitin carrier protein (E2) enzyme that mediates Atg8 lipidation.
Volume: 282
Issue: 11
Pages: 8036-43
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Publication
23255127 | -
First Author: Flanagan MD
Year: 2013
Journal: Cell Cycle
Title: An Atg10-like E2 enzyme is essential for cell cycle progression but not autophagy in Schizosaccharomyces pombe.
Volume: 12
Issue: 2
Pages: 271-7
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Protein Domain
IPR007135 | Atg3/Atg10
Type: Family
Description: This entry represents a group of ubiquitin-like-conjugating enzymes, including Atg3 and Atg10.Atg3 is the E2 enzyme for the LC3 lipidation process []. It is essential for autophagocytosis. The super protein complex, the Atg16L complex, consists of multiple Atg12-Atg5 conjugates. Atg16L has an E3-like role in the LC3 lipidation reaction. The activated intermediate, LC3-Atg3 (E2), is recruited to the site where the lipidation takes place []. Atg3 catalyses the conjugation of Atg8 and phosphatidylethanolamine (PE). Atg3 has an alpha/β-fold, and its core region is topologically similar to canonical E2 enzymes. Atg3 has two regions inserted in the core region and another with a long α-helical structure that protrudes from the core region as far as 30 A []. It interacts with atg8 through an intermediate thioester bond between Cys-288 and the C-terminal Gly of atg8. It also interacts with the C-terminal region of the E1-like atg7 enzyme.Atg10 acts as an E2-like enzyme that catalyzes the conjugation of ATG12 to ATG5 [].
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Protein Domain
IPR042523 | Atg7_N_2
Type: Homologous_superfamily
Description: This superfamily represents the second subdomain found in the N-terminal domain of ubiquitin-like modifier-activating enzyme Atg7. In Arabidopsis, the N-terminal domain binds the E2 enzymes Atg10 and Atg3 [].
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Protein Domain
IPR042522 | Atg7_N_1
Type: Homologous_superfamily
Description: This superfamily represents the first subdomain found in the N-terminal domain of ubiquitin-like modifier-activating enzyme Atg7. In Arabidopsis, the N-terminal domain binds the E2 enzymes Atg10 and Atg3 [].
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Publication
22847423 | J:188694
First Author: Wang Y
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Autophagic activity dictates the cellular response to oncogenic RAS.
Volume: 109
Issue: 33
Pages: 13325-30
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Publication
33459130 | J:315201
First Author: Vujić N
Year: 2021
Journal: Autophagy
Title: ATG7 is dispensable for LC3-PE conjugation in thioglycolate-elicited mouse peritoneal macrophages.
Volume: 17
Issue: 11
Pages: 3402-3407
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Protein
S4R1T0
Organism: Mus musculus/domesticus
Length: 232  
Fragment?: true
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Protein
S4R2P7
Organism: Mus musculus/domesticus
Length: 222  
Fragment?: true
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Protein
S4R1N8
Organism: Mus musculus/domesticus
Length: 172  
Fragment?: true
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Protein
Q9D906
Organism: Mus musculus/domesticus
Length: 698  
Fragment?: false
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Protein
A0A0A0MQN4
Organism: Mus musculus/domesticus
Length: 741  
Fragment?: false
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Protein
S4R2T5
Organism: Mus musculus/domesticus
Length: 671  
Fragment?: false
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Protein
Q3TM87
Organism: Mus musculus/domesticus
Length: 698  
Fragment?: false
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Protein
Q3TAB9
Organism: Mus musculus/domesticus
Length: 698  
Fragment?: false
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Protein
S4R2D5
Organism: Mus musculus/domesticus
Length: 618  
Fragment?: false
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Publication
31209365 | J:282705
First Author: Li Z
Year: 2020
Journal: Cell Death Differ
Title: Haploinsufficiency of GCP4 induces autophagy and leads to photoreceptor degeneration due to defective spindle assembly in retina.
Volume: 27
Issue: 2
Pages: 556-572
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Publication
31345090 | J:307231
First Author: Xu X
Year: 2019
Journal: Autophagy
Title: Gene essentiality of Tubgcp4: dosage effect and autophagy regulation in retinal photoreceptors.
Volume: 15
Issue: 10
Pages: 1834-1837
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Publication
23026405 | J:192048
First Author: Ghavami S
Year: 2012
Journal: Biochim Biophys Acta
Title: Autophagy regulates trans fatty acid-mediated apoptosis in primary cardiac myofibroblasts.
Volume: 1823
Issue: 12
Pages: 2274-86
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Publication
23230293 | J:192546
First Author: Ko Y
Year: 2013
Journal: Infect Immun
Title: Active escape of Orientia tsutsugamushi from cellular autophagy.
Volume: 81
Issue: 2
Pages: 552-9
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Publication
24637330 | J:212487
First Author: Ghavami S
Year: 2014
Journal: Biochim Biophys Acta
Title: Airway mesenchymal cell death by mevalonate cascade inhibition: integration of autophagy, unfolded protein response and apoptosis focusing on Bcl2 family proteins.
Volume: 1843
Issue: 7
Pages: 1259-71
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Publication
25127936 | J:218465
First Author: Kundu S
Year: 2014
Journal: Biochim Biophys Acta
Title: Hydrogen sulfide mitigates hyperglycemic remodeling via liver kinase B1-adenosine monophosphate-activated protein kinase signaling.
Volume: 1843
Issue: 12
Pages: 2816-26
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Publication
29108912 | J:257547
First Author: Yeganeh B
Year: 2018
Journal: Biochim Biophys Acta
Title: Autophagy activation is required for influenza A virus-induced apoptosis and replication.
Volume: 1865
Issue: 2
Pages: 364-378
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Publication
15489334 | -
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
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Publication
21183079 | J:292518
First Author: Huttlin EL
Year: 2010
Journal: Cell
Title: A tissue-specific atlas of mouse protein phosphorylation and expression.
Volume: 143
Issue: 7
Pages: 1174-89
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