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Cap2
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0.018s
Type
Details
Score
Publication
First Author:
Du X
Year:
2008
Journal:
MGI Direct Data Submission
Title:
Cap2 is an allele of Ltbp3 (latent transforming growth factors beta binding protein 3) and is involved in TGF-beta signaling
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Protein
Organism:
Mus musculus/domesticus
Length:
767
Fragment?:
false
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Publication
First Author:
Werner M
Year:
2011
Journal:
Nucleic Acids Res
Title:
2'-O-ribose methylation of cap2 in human: function and evolution in a horizontally mobile family.
Volume:
39
Issue:
11
Pages:
4756-68
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Allele
Name:
cyclase associated actin cytoskeleton regulatory protein 2; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type:
Endonuclease-mediated
Attribute String:
Conditional ready, No functional change
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Protein Coding Gene
Type:
protein_coding_gene
Organism:
mouse, laboratory
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Protein Domain
Type:
Domain
Description:
This entry represents a domain found in the E2/UBC superfamily of proteins found in several bacteria. The active site residues are similar to the eukaryotic E2 proteins but lack the conserved asparagine [, ]. Members of this family are usually fused to an E1 domain at the C terminus. The protein is usually in the gene neighbourhoodof a gene encoding a member of the pol-beta nucleotidyltransferase superfamily []. Many of the operons in this family are in ICE-like mobile elements and plasmids [].Proteins containing this domain include CD-NTase-associated protein 2 (Cap2) from Escherichia coli. Cap2 is associated with CD-NTase protein, which synthesizes cyclic nucleotides in response to infection; these serve as specific second messenger signals [].
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Publication
First Author:
Dohnalkova M
Year:
2023
Journal:
Cell Rep
Title:
Essential roles of RNA cap-proximal ribose methylation in mammalian embryonic development and fertility.
Volume:
42
Issue:
7
Pages:
112786
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Publication
First Author:
Palmgren S
Year:
2001
Journal:
J Cell Biol
Title:
Interactions with PIP2, ADP-actin monomers, and capping protein regulate the activity and localization of yeast twinfilin.
Volume:
155
Issue:
2
Pages:
251-60
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Publication
First Author:
Cohen D
Year:
2019
Journal:
Nature
Title:
Cyclic GMP-AMP signalling protects bacteria against viral infection.
Volume:
574
Issue:
7780
Pages:
691-695
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Publication
First Author:
Burroughs AM
Year:
2008
Journal:
J Struct Biol
Title:
Anatomy of the E2 ligase fold: implications for enzymology and evolution of ubiquitin/Ub-like protein conjugation.
Volume:
162
Issue:
2
Pages:
205-18
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Publication
First Author:
Iyer LM
Year:
2006
Journal:
Genome Biol
Title:
The prokaryotic antecedents of the ubiquitin-signaling system and the early evolution of ubiquitin-like beta-grasp domains.
Volume:
7
Issue:
7
Pages:
R60
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