|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 201 to 300 out of 336 for Gsdmd

0.04s
Type Details Score
Publication  
First Author: Spurlock M
Year: 2023
Journal: Cells
Title: The Inflammasome-Dependent Dysfunction and Death of Retinal Ganglion Cells after Repetitive Intraocular Pressure Spikes.
Volume: 12
Issue: 22
Publication
First Author: Eislmayr K
Year: 2022
Journal: Sci Adv
Title: Nonredundancy of IL-1α and IL-1β is defined by distinct regulation of tissues orchestrating resistance versus tolerance to infection.
Volume: 8
Issue: 9
Pages: eabj7293
Publication
First Author: Huang LS
Year: 2020
Journal: Immunity
Title: mtDNA Activates cGAS Signaling and Suppresses the YAP-Mediated Endothelial Cell Proliferation Program to Promote Inflammatory Injury.
Volume: 52
Issue: 3
Pages: 475-486.e5
Publication
First Author: Wang Y
Year: 2018
Journal: J Immunol
Title: Cutting Edge: The Heat Shock Protein gp96 Activates Inflammasome-Signaling Platforms in APCs.
Volume: 201
Issue: 8
Pages: 2209-2214
Publication
First Author: Hashimoto S
Year: 2023
Journal: Sci Rep
Title: Neuronal glutathione loss leads to neurodegeneration involving gasdermin activation.
Volume: 13
Issue: 1
Pages: 1109
Publication
First Author: Mascarenhas DPA
Year: 2017
Journal: PLoS Pathog
Title: Inhibition of caspase-1 or gasdermin-D enable caspase-8 activation in the Naip5/NLRC4/ASC inflammasome.
Volume: 13
Issue: 8
Pages: e1006502
Publication  
First Author: de Vasconcelos NM
Year: 2019
Journal: Life Sci Alliance
Title: DPP8/DPP9 inhibition elicits canonical Nlrp1b inflammasome hallmarks in murine macrophages.
Volume: 2
Issue: 1
Publication    
First Author: Deets KA
Year: 2021
Journal: Elife
Title: Inflammasome activation leads to cDC1-independent cross-priming of CD8 T cells by epithelial cell-derived antigen.
Volume: 10
Publication
First Author: Shim DW
Year: 2024
Journal: Exp Mol Med
Title: Deficiency of circadian clock gene Bmal1 exacerbates noncanonical inflammasome-mediated pyroptosis and lethality via Rev-erbα-C/EBPβ-SAA1 axis.
Volume: 56
Issue: 2
Pages: 370-382
Publication
First Author: Wu J
Year: 2021
Journal: Immunity
Title: APOL1 risk variants in individuals of African genetic ancestry drive endothelial cell defects that exacerbate sepsis.
Volume: 54
Issue: 11
Pages: 2632-2649.e6
Publication
First Author: Bauer DL
Year: 2023
Journal: J Immunol
Title: The Adjuvant Combination of dmLT and Monophosphoryl Lipid A Activates the Canonical, Nonpyroptotic NLRP3 Inflammasome in Dendritic Cells and Significantly Interacts to Expand Antigen-Specific CD4 T Cells.
Volume: 210
Issue: 10
Pages: 1519-1530
Publication  
First Author: Chen KW
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: RIPK1 activates distinct gasdermins in macrophages and neutrophils upon pathogen blockade of innate immune signaling.
Volume: 118
Issue: 28
Publication
First Author: Wu C
Year: 2019
Journal: Immunity
Title: Inflammasome Activation Triggers Blood Clotting and Host Death through Pyroptosis.
Volume: 50
Issue: 6
Pages: 1401-1411.e4
Publication
First Author: Zhang C
Year: 2020
Journal: Cell Death Dis
Title: Induction of ASC pyroptosis requires gasdermin D or caspase-1/11-dependent mediators and IFNβ from pyroptotic macrophages.
Volume: 11
Issue: 6
Pages: 470
Publication
First Author: Tamura M
Year: 2007
Journal: Genomics
Title: Members of a novel gene family, Gsdm, are expressed exclusively in the epithelium of the skin and gastrointestinal tract in a highly tissue-specific manner.
Volume: 89
Issue: 5
Pages: 618-29
Publication
First Author: Banoth B
Year: 2020
Journal: J Biol Chem
Title: ZBP1 promotes fungi-induced inflammasome activation and pyroptosis, apoptosis, and necroptosis (PANoptosis).
Volume: 295
Issue: 52
Pages: 18276-18283
Publication  
First Author: Alphonse MP
Year: 2021
Journal: Sci Transl Med
Title: Pan-caspase inhibition as a potential host-directed immunotherapy against MRSA and other bacterial skin infections.
Volume: 13
Issue: 601
Publication
First Author: Banerjee I
Year: 2018
Journal: Immunity
Title: Gasdermin D Restrains Type I Interferon Response to Cytosolic DNA by Disrupting Ionic Homeostasis.
Volume: 49
Issue: 3
Pages: 413-426.e5
Publication
First Author: Batista SJ
Year: 2020
Journal: Nat Commun
Title: Gasdermin-D-dependent IL-1α release from microglia promotes protective immunity during chronic Toxoplasma gondii infection.
Volume: 11
Issue: 1
Pages: 3687
Publication
First Author: Howard JE
Year: 2021
Journal: Stem Cell Reports
Title: IL-18R-mediated HSC quiescence and MLKL-dependent cell death limit hematopoiesis during infection-induced shock.
Volume: 16
Issue: 12
Pages: 2887-2899
Publication
First Author: Zhou Y
Year: 2020
Journal: Immunity
Title: Blockade of the Phagocytic Receptor MerTK on Tumor-Associated Macrophages Enhances P2X7R-Dependent STING Activation by Tumor-Derived cGAMP.
Volume: 52
Issue: 2
Pages: 357-373.e9
Publication
First Author: Baroja-Mazo A
Year: 2019
Journal: Sci Rep
Title: Early endosome autoantigen 1 regulates IL-1β release upon caspase-1 activation independently of gasdermin D membrane permeabilization.
Volume: 9
Issue: 1
Pages: 5788
Publication
First Author: Doglio MG
Year: 2023
Journal: Sci Immunol
Title: Myeloid OTULIN deficiency couples RIPK3-dependent cell death to Nlrp3 inflammasome activation and IL-1β secretion.
Volume: 8
Issue: 89
Pages: eadf4404
Publication
First Author: Zhou B
Year: 2020
Journal: Nat Microbiol
Title: Extracellular SQSTM1 mediates bacterial septic death in mice through insulin receptor signalling.
Volume: 5
Issue: 12
Pages: 1576-1587
Publication
First Author: Rauch I
Year: 2017
Journal: Immunity
Title: NAIP-NLRC4 Inflammasomes Coordinate Intestinal Epithelial Cell Expulsion with Eicosanoid and IL-18 Release via Activation of Caspase-1 and -8.
Volume: 46
Issue: 4
Pages: 649-659
Publication
First Author: Zhang H
Year: 2020
Journal: Cell Host Microbe
Title: TMEM173 Drives Lethal Coagulation in Sepsis.
Volume: 27
Issue: 4
Pages: 556-570.e6
Publication  
First Author: Qu Z
Year: 2020
Journal: Sci Adv
Title: Mycobacterial EST12 activates a RACK1-NLRP3-gasdermin D pyroptosis-IL-1β immune pathway.
Volume: 6
Issue: 43
Publication
First Author: Cong J
Year: 2024
Journal: Immunity
Title: Bile acids modified by the intestinal microbiota promote colorectal cancer growth by suppressing CD8(+) T cell effector functions.
Volume: 57
Issue: 4
Pages: 876-889.e11
Publication
First Author: Russo AJ
Year: 2021
Journal: Nat Immunol
Title: Intracellular immune sensing promotes inflammation via gasdermin D-driven release of a lectin alarmin.
Volume: 22
Issue: 2
Pages: 154-165
Publication
First Author: Bambouskova M
Year: 2021
Journal: Cell Rep
Title: Itaconate confers tolerance to late NLRP3 inflammasome activation.
Volume: 34
Issue: 10
Pages: 108756
Publication
First Author: Minns MS
Year: 2023
Journal: Nat Commun
Title: NLRP3 selectively drives IL-1β secretion by Pseudomonas aeruginosa infected neutrophils and regulates corneal disease severity.
Volume: 14
Issue: 1
Pages: 5832
Publication
First Author: Leimeister C
Year: 1999
Journal: Dev Genet
Title: Screen for genes regulated during early kidney morphogenesis.
Volume: 24
Issue: 3-4
Pages: 273-83
Publication
First Author: Xu W
Year: 2021
Journal: Cell Metab
Title: Apaf-1 Pyroptosome Senses Mitochondrial Permeability Transition.
Volume: 33
Issue: 2
Pages: 424-436.e10
Publication
First Author: Hara H
Year: 2018
Journal: Cell
Title: The NLRP6 Inflammasome Recognizes Lipoteichoic Acid and Regulates Gram-Positive Pathogen Infection.
Volume: 175
Issue: 6
Pages: 1651-1664.e14
Publication
First Author: Muri J
Year: 2020
Journal: Cell Rep
Title: Cyclopentenone Prostaglandins and Structurally Related Oxidized Lipid Species Instigate and Share Distinct Pro- and Anti-inflammatory Pathways.
Volume: 30
Issue: 13
Pages: 4399-4417.e7
Publication
First Author: Briard B
Year: 2020
Journal: Nature
Title: Galactosaminogalactan activates the inflammasome to provide host protection.
Volume: 588
Issue: 7839
Pages: 688-692
Publication
First Author: Deng M
Year: 2018
Journal: Immunity
Title: The Endotoxin Delivery Protein HMGB1 Mediates Caspase-11-Dependent Lethality in Sepsis.
Volume: 49
Issue: 4
Pages: 740-753.e7
Publication
First Author: Bharadwaj R
Year: 2023
Journal: Immunity
Title: Methotrexate suppresses psoriatic skin inflammation by inhibiting muropeptide transporter SLC46A2 activity.
Volume: 56
Issue: 5
Pages: 998-1012.e8
Publication
First Author: Nozaki K
Year: 2022
Journal: Nature
Title: Caspase-7 activates ASM to repair gasdermin and perforin pores.
Volume: 606
Issue: 7916
Pages: 960-967
Publication
First Author: Chauhan D
Year: 2018
Journal: Cell Rep
Title: BAX/BAK-Induced Apoptosis Results in Caspase-8-Dependent IL-1β Maturation in Macrophages.
Volume: 25
Issue: 9
Pages: 2354-2368.e5
Publication
First Author: Muendlein HI
Year: 2020
Journal: Science
Title: cFLIPL protects macrophages from LPS-induced pyroptosis via inhibition of complex II formation.
Volume: 367
Issue: 6484
Pages: 1379-1384
Publication
First Author: Donado CA
Year: 2020
Journal: Cell Rep
Title: A Two-Cell Model for IL-1β Release Mediated by Death-Receptor Signaling.
Volume: 31
Issue: 1
Pages: 107466
Publication
First Author: Zhu S
Year: 2017
Journal: Nature
Title: Nlrp9b inflammasome restricts rotavirus infection in intestinal epithelial cells.
Volume: 546
Issue: 7660
Pages: 667-670
Publication
First Author: Muendlein HI
Year: 2021
Journal: Nat Commun
Title: ZBP1 promotes LPS-induced cell death and IL-1β release via RHIM-mediated interactions with RIPK1.
Volume: 12
Issue: 1
Pages: 86
Publication
First Author: Zheng M
Year: 2020
Journal: Cell
Title: Caspase-6 Is a Key Regulator of Innate Immunity, Inflammasome Activation, and Host Defense.
Volume: 181
Issue: 3
Pages: 674-687.e13
Publication  
First Author: Santos JC
Year: 2018
Journal: EMBO J
Title: LPS targets host guanylate-binding proteins to the bacterial outer membrane for non-canonical inflammasome activation.
Volume: 37
Issue: 6
Publication
First Author: Benmerzoug S
Year: 2018
Journal: Nat Commun
Title: STING-dependent sensing of self-DNA drives silica-induced lung inflammation.
Volume: 9
Issue: 1
Pages: 5226
Publication
First Author: Saavedra PHV
Year: 2018
Journal: Nat Commun
Title: Apoptosis of intestinal epithelial cells restricts Clostridium difficile infection in a model of pseudomembranous colitis.
Volume: 9
Issue: 1
Pages: 4846
Publication
First Author: Kerur N
Year: 2018
Journal: Nat Med
Title: cGAS drives noncanonical-inflammasome activation in age-related macular degeneration.
Volume: 24
Issue: 1
Pages: 50-61
Publication
First Author: Lawlor KE
Year: 2017
Journal: Cell Rep
Title: XIAP Loss Triggers RIPK3- and Caspase-8-Driven IL-1β Activation and Cell Death as a Consequence of TLR-MyD88-Induced cIAP1-TRAF2 Degradation.
Volume: 20
Issue: 3
Pages: 668-682
Publication
First Author: Vince JE
Year: 2018
Journal: Cell Rep
Title: The Mitochondrial Apoptotic Effectors BAX/BAK Activate Caspase-3 and -7 to Trigger NLRP3 Inflammasome and Caspase-8 Driven IL-1β Activation.
Volume: 25
Issue: 9
Pages: 2339-2353.e4
Publication
First Author: Jain A
Year: 2020
Journal: Nat Immunol
Title: T cells instruct myeloid cells to produce inflammasome-independent IL-1β and cause autoimmunity.
Volume: 21
Issue: 1
Pages: 65-74
Publication
First Author: Zhang Y
Year: 2021
Journal: PLoS Biol
Title: A unique death pathway keeps RIPK1 D325A mutant mice in check at embryonic day 10.5.
Volume: 19
Issue: 8
Pages: e3001304
Publication
First Author: Wei L
Year: 2020
Journal: J Biol Chem
Title: GGPP depletion initiates metaflammation through disequilibrating CYB5R3-dependent eicosanoid metabolism.
Volume: 295
Issue: 47
Pages: 15988-16001
Publication  
First Author: Kuriakose T
Year: 2016
Journal: Sci Immunol
Title: ZBP1/DAI is an innate sensor of influenza virus triggering the NLRP3 inflammasome and programmed cell death pathways.
Volume: 1
Issue: 2
Publication
First Author: Karki R
Year: 2018
Journal: Cell
Title: IRF8 Regulates Transcription of Naips for NLRC4 Inflammasome Activation.
Volume: 173
Issue: 4
Pages: 920-933.e13
Publication
First Author: Karki R
Year: 2021
Journal: Cell
Title: Synergism of TNF-α and IFN-γ Triggers Inflammatory Cell Death, Tissue Damage, and Mortality in SARS-CoV-2 Infection and Cytokine Shock Syndromes.
Volume: 184
Issue: 1
Pages: 149-168.e17
Publication
First Author: Simpson DS
Year: 2022
Journal: Immunity
Title: Interferon-γ primes macrophages for pathogen ligand-induced killing via a caspase-8 and mitochondrial cell death pathway.
Volume: 55
Issue: 3
Pages: 423-441.e9
Publication      
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
Publication      
First Author: The Jackson Laboratory
Year: 2005
Journal: Unpublished
Title: Information obtained from The Jackson Laboratory, Bar Harbor, ME
Publication        
First Author: Mouse Genome Database and National Center for Biotechnology Information Editorial Staff Collaboration
Year: 2001
Title: LocusLink Collaboration
Publication        
First Author: The Gene Ontology Consortium
Year: 2016
Title: Automatic assignment of GO terms using logical inference, based on on inter-ontology links
Publication      
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
Publication
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
Publication        
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication
First Author: Ratitong B
Year: 2021
Journal: Cell Rep
Title: β-Glucan-stimulated neutrophil secretion of IL-1α is independent of GSDMD and mediated through extracellular vesicles.
Volume: 35
Issue: 7
Pages: 109139
Publication  
First Author: Zhang BL
Year: 2023
Journal: Front Pharmacol
Title: Inhibition of GSDMD activation by Z-LLSD-FMK or Z-YVAD-FMK reduces vascular inflammation and atherosclerotic lesion development in ApoE(-/-) mice.
Volume: 14
Pages: 1184588
Allele
Name: gasdermin D; endonuclease-mediated mutation 2, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
Strain
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
Publication
First Author: Sborgi L
Year: 2016
Journal: EMBO J
Title: GSDMD membrane pore formation constitutes the mechanism of pyroptotic cell death.
Volume: 35
Issue: 16
Pages: 1766-78
Allele
Name: gasdermin D; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
Strain
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
Allele
Name: gasdermin D; mutation 1, Bruce Beutler
Allele Type: Chemically induced (ENU)
Attribute String: Not Specified