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Search results 201 to 300 out of 915 for Nf1

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Type Details Score
Publication
10586246 | J:59850
 
First Author: Rosenbaum T
Year: 1999
Journal: Ann N Y Acad Sci
Title: Neurofibromin, the neurofibromatosis type 1 Ras-GAP, is required for appropriate P0 expression and myelination.
Volume: 883
Pages: 203-14
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Publication
12573431 | J:81524
First Author: Dasgupta B
Year: 2003
Journal: Curr Opin Genet Dev
Title: Neurofibromatosis 1: closing the GAP between mice and men.
Volume: 13
Issue: 1
Pages: 20-7
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Publication
18213578 | J:130164
First Author: Roth TM
Year: 2008
Journal: Dev Dyn
Title: Influence of hormones and hormone metabolites on the growth of Schwann cells derived from embryonic stem cells and on tumor cell lines expressing variable levels of neurofibromin.
Volume: 237
Issue: 2
Pages: 513-24
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Publication
22901811 | J:187986
First Author: Wang Y
Year: 2012
Journal: Cell
Title: ERK inhibition rescues defects in fate specification of Nf1-deficient neural progenitors and brain abnormalities.
Volume: 150
Issue: 4
Pages: 816-30
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Publication
7477259 | J:29825
First Author: Henkemeyer M
Year: 1995
Journal: Nature
Title: Vascular system defects and neuronal apoptosis in mice lacking ras GTPase-activating protein.
Volume: 377
Issue: 6551
Pages: 695-701
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Publication
32358581 | J:291790
First Author: Guo X
Year: 2020
Journal: Nat Commun
Title: Midkine activation of CD8+ T cells establishes a neuron-immune-cancer axis responsible for low-grade glioma growth.
Volume: 11
Issue: 1
Pages: 2177
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Publication
34428430 | J:314108
First Author: Jecrois ES
Year: 2021
Journal: Dev Cell
Title: Treatment during a developmental window prevents NF1-associated optic pathway gliomas by targeting Erk-dependent migrating glial progenitors.
Volume: 56
Issue: 20
Pages: 2871-2885.e6
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Publication
35311647 | J:322614
   
First Author: Patritti Cram J
Year: 2022
Journal: Elife
Title: P2RY14 cAMP signaling regulates Schwann cell precursor self-renewal, proliferation, and nerve tumor initiation in a mouse model of neurofibromatosis.
Volume: 11
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Publication
33177525 | J:297927
First Author: Bok S
Year: 2020
Journal: Nat Commun
Title: MEKK2 mediates aberrant ERK activation in neurofibromatosis type I.
Volume: 11
Issue: 1
Pages: 5704
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Publication
33293695 | J:301473
First Author: Na Y
Year: 2021
Journal: Oncogene
Title: MicroRNA-155 contributes to plexiform neurofibroma growth downstream of MEK.
Volume: 40
Issue: 5
Pages: 951-963
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Publication
21439418 | J:172512
First Author: Zhang W
Year: 2011
Journal: Bone
Title: Primary osteopathy of vertebrae in a neurofibromatosis type 1 murine model.
Volume: 48
Issue: 6
Pages: 1378-87
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Publication
24997609 | J:227603
First Author: de la Croix Ndong J
Year: 2014
Journal: Nat Med
Title: Asfotase-α improves bone growth, mineralization and strength in mouse models of neurofibromatosis type-1.
Volume: 20
Issue: 8
Pages: 904-10
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Publication
21352477 | J:185707
First Author: van der Vaart T
Year: 2011
Journal: Genes Brain Behav
Title: Motor deficits in neurofibromatosis type 1 mice: the role of the cerebellum.
Volume: 10
Issue: 4
Pages: 404-9
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Publication
8314000 | J:16739
First Author: Huynh DP
Year: 1994
Journal: Dev Biol
Title: Differential expression and tissue distribution of type I and type II neurofibromins during mouse fetal development.
Volume: 161
Issue: 2
Pages: 538-51
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Publication
7633452 | J:25208
First Author: Danglot G
Year: 1995
Journal: Hum Mol Genet
Title: Neurofibromatosis 1 (NF1) mRNAs expressed in the central nervous system are differentially spliced in the 5' part of the gene.
Volume: 4
Issue: 5
Pages: 915-20
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Publication
21319287 | J:215873
First Author: Wu J
Year: 2012
Journal: Pediatr Blood Cancer
Title: Preclincial testing of sorafenib and RAD001 in the Nf(flox/flox) ;DhhCre mouse model of plexiform neurofibroma using magnetic resonance imaging.
Volume: 58
Issue: 2
Pages: 173-80
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Publication
23221341 | J:194157
First Author: Jessen WJ
Year: 2013
Journal: J Clin Invest
Title: MEK inhibition exhibits efficacy in human and mouse neurofibromatosis tumors.
Volume: 123
Issue: 1
Pages: 340-7
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Publication
32810864 | J:295936
First Author: Vasiljevski ER
Year: 2020
Journal: PLoS One
Title: Evaluating modified diets and dietary supplement therapies for reducing muscle lipid accumulation and improving muscle function in neurofibromatosis type 1 (NF1).
Volume: 15
Issue: 8
Pages: e0237097
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Publication
22307743 | J:211765
First Author: Alanne MH
Year: 2012
Journal: J Cell Biochem
Title: Phenotypic characterization of transgenic mice harboring Nf1+/- or Nf1-/- osteoclasts in otherwise Nf1+/+ background.
Volume: 113
Issue: 6
Pages: 2136-46
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Publication
20124472 | J:157155
First Author: Banerjee S
Year: 2010
Journal: Cancer Res
Title: The neurofibromatosis type 1 tumor suppressor controls cell growth by regulating signal transducer and activator of transcription-3 activity in vitro and in vivo.
Volume: 70
Issue: 4
Pages: 1356-66
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Publication
21551250 | J:173624
First Author: Le LQ
Year: 2011
Journal: Cancer Res
Title: Susceptible stages in Schwann cells for NF1-associated plexiform neurofibroma development.
Volume: 71
Issue: 13
Pages: 4686-95
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Publication
19727076 | J:152381
First Author: Lauchle JO
Year: 2009
Journal: Nature
Title: Response and resistance to MEK inhibition in leukaemias initiated by hyperactive Ras.
Volume: 461
Issue: 7262
Pages: 411-4
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Publication
19191334 | J:156205
First Author: Yeh TH
Year: 2009
Journal: Glia
Title: Microarray analyses reveal regional astrocyte heterogeneity with implications for neurofibromatosis type 1 (NF1)-regulated glial proliferation.
Volume: 57
Issue: 11
Pages: 1239-49
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Publication
14523097 | J:120166
First Author: Dasgupta B
Year: 2003
Journal: J Neurosci
Title: The neurofibromatosis 1 gene product neurofibromin regulates pituitary adenylate cyclase-activating polypeptide-mediated signaling in astrocytes.
Volume: 23
Issue: 26
Pages: 8949-54
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Publication
18272679 | J:132220
First Author: Lush ME
Year: 2008
Journal: J Neurosci
Title: Neurofibromin is required for barrel formation in the mouse somatosensory cortex.
Volume: 28
Issue: 7
Pages: 1580-7
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19574548 | J:164937
First Author: Xu J
Year: 2009
Journal: Circ Res
Title: Cardiomyocyte-specific loss of neurofibromin promotes cardiac hypertrophy and dysfunction.
Volume: 105
Issue: 3
Pages: 304-11
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Publication
23863460 | J:202235
First Author: Sharma R
Year: 2013
Journal: Hum Mol Genet
Title: Hyperactive Ras/MAPK signaling is critical for tibial nonunion fracture in neurofibromin-deficient mice.
Volume: 22
Issue: 23
Pages: 4818-28
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Publication
20410111 | J:159840
First Author: Brown JA
Year: 2010
Journal: J Neurosci
Title: Defective cAMP generation underlies the sensitivity of CNS neurons to neurofibromatosis-1 heterozygosity.
Volume: 30
Issue: 16
Pages: 5579-89
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Publication
20160346 | J:158570
First Author: Lasater EA
Year: 2010
Journal: J Clin Invest
Title: Genetic and cellular evidence of vascular inflammation in neurofibromin-deficient mice and humans.
Volume: 120
Issue: 3
Pages: 859-70
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Publication
25786243 | J:229201
First Author: Rhodes SD
Year: 2015
Journal: PLoS One
Title: Dystrophic spinal deformities in a neurofibromatosis type 1 murine model.
Volume: 10
Issue: 3
Pages: e0119093
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Publication
31445228 | J:293644
 
First Author: Rizwan G
Year: 2019
Journal: Epilepsy Res
Title: Increased seizure susceptibility in a mouse model of neurofibromatosis type 1.
Volume: 156
Pages: 106190
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Publication
15804420 | J:104976
First Author: Yu X
Year: 2005
Journal: Bone
Title: Neurofibromin and its inactivation of Ras are prerequisites for osteoblast functioning.
Volume: 36
Issue: 5
Pages: 793-802
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Publication
16893911 | J:114925
First Author: Wu X
Year: 2006
Journal: Hum Mol Genet
Title: Neurofibromin plays a critical role in modulating osteoblast differentiation of mesenchymal stem/progenitor cells.
Volume: 15
Issue: 19
Pages: 2837-45
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Publication
10498620 | J:57842
First Author: Mahgoub N
Year: 1999
Journal: Blood
Title: In vitro and in vivo effects of a farnesyltransferase inhibitor on Nf1-deficient hematopoietic cells.
Volume: 94
Issue: 7
Pages: 2469-76
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Publication
17236191 | J:156102
First Author: Nebesio TD
Year: 2007
Journal: Glia
Title: Neurofibromin-deficient Schwann cells have increased lysophosphatidic acid dependent survival and migration-implications for increased neurofibroma formation during pregnancy.
Volume: 55
Issue: 5
Pages: 527-36
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Publication
16835260 | J:112050
First Author: Yang FC
Year: 2006
Journal: Hum Mol Genet
Title: Nf1+/- mast cells induce neurofibroma like phenotypes through secreted TGF-beta signaling.
Volume: 15
Issue: 16
Pages: 2421-37
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Publication
18442999 | J:137662
First Author: Lasater EA
Year: 2008
Journal: Hum Mol Genet
Title: Nf1+/- mice have increased neointima formation via hyperactivation of a Gleevec sensitive molecular pathway.
Volume: 17
Issue: 15
Pages: 2336-44
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Publication
11751683 | J:73716
First Author: Gutmann DH
Year: 2001
Journal: Hum Mol Genet
Title: Heterozygosity for the neurofibromatosis 1 (NF1) tumor suppressor results in abnormalities in cell attachment, spreading and motility in astrocytes.
Volume: 10
Issue: 26
Pages: 3009-16
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Publication
35589737 | J:324999
First Author: Anastasaki C
Year: 2022
Journal: Nat Commun
Title: Neuronal hyperexcitability drives central and peripheral nervous system tumor progression in models of neurofibromatosis-1.
Volume: 13
Issue: 1
Pages: 2785
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Publication
1946382 | J:31498
First Author: Gutmann DH
Year: 1991
Journal: Proc Natl Acad Sci U S A
Title: Identification of the neurofibromatosis type 1 gene product.
Volume: 88
Issue: 21
Pages: 9658-62
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7568895 | J:30191
 
First Author: Gutmann DH
Year: 1995
Journal: Prog Brain Res
Title: Expression of the neurofibromatosis type 1 (NF1) gene during mouse embryonic development.
Volume: 105
Pages: 327-35
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Publication
19074905 | J:142234
First Author: Daginakatte GC
Year: 2008
Journal: Cancer Res
Title: Increased c-Jun-NH2-kinase signaling in neurofibromatosis-1 heterozygous microglia drives microglia activation and promotes optic glioma proliferation.
Volume: 68
Issue: 24
Pages: 10358-66
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Publication
27283753 | J:243903
First Author: Petrella LI
Year: 2016
Journal: Genes Brain Behav
Title: Brain and behaviour phenotyping of a mouse model of neurofibromatosis type-1: an MRI/DTI study on social cognition.
Volume: 15
Issue: 7
Pages: 637-46
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Publication
20876733 | J:164880
First Author: Lee DY
Year: 2010
Journal: Genes Dev
Title: Neurofibromatosis-1 regulates neuroglial progenitor proliferation and glial differentiation in a brain region-specific manner.
Volume: 24
Issue: 20
Pages: 2317-29
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Publication
25381154 | J:218215
First Author: Warrington NM
Year: 2015
Journal: Cancer Res
Title: The cyclic AMP pathway is a sex-specific modifier of glioma risk in type I neurofibromatosis patients.
Volume: 75
Issue: 1
Pages: 16-21
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Publication
29162814 | J:257198
First Author: Ma Z
Year: 2017
Journal: Nat Commun
Title: TrkB dependent adult hippocampal progenitor differentiation mediates sustained ketamine antidepressant response.
Volume: 8
Issue: 1
Pages: 1668
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Publication
16271875 | J:103691
First Author: Li W
Year: 2005
Journal: Curr Biol
Title: The HMG-CoA reductase inhibitor lovastatin reverses the learning and attention deficits in a mouse model of neurofibromatosis type 1.
Volume: 15
Issue: 21
Pages: 1961-7
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Publication
12881715 | J:84658
First Author: Gutmann DH
Year: 2003
Journal: Oncogene
Title: Mlh1 deficiency accelerates myeloid leukemogenesis in neurofibromatosis 1 (Nf1) heterozygous mice.
Volume: 22
Issue: 29
Pages: 4581-5
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Publication
22851646 | J:193516
First Author: Wallace MD
Year: 2012
Journal: Genetics
Title: Comparative oncogenomics implicates the neurofibromin 1 gene (NF1) as a breast cancer driver.
Volume: 192
Issue: 2
Pages: 385-96
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Publication
12082543 | J:77141
First Author: Gutmann DH
Year: 2002
Journal: Neoplasia
Title: Mouse models of neurofibromatosis 1 and 2.
Volume: 4
Issue: 4
Pages: 279-90
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Publication
17096025 | J:139277
First Author: Shapira S
Year: 2007
Journal: Cell Death Differ
Title: The tumor suppressor neurofibromin confers sensitivity to apoptosis by Ras-dependent and Ras-independent pathways.
Volume: 14
Issue: 5
Pages: 895-906
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Publication
22751498 | J:185345
First Author: Stowe IB
Year: 2012
Journal: Genes Dev
Title: A shared molecular mechanism underlies the human rasopathies Legius syndrome and Neurofibromatosis-1.
Volume: 26
Issue: 13
Pages: 1421-6
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Publication
24947449 | J:215491
 
First Author: Kühnisch J
Year: 2014
Journal: Bone
Title: Neurofibromin inactivation impairs osteocyte development in Nf1Prx1 and Nf1Col1 mouse models.
Volume: 66
Pages: 155-62
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24465906 | J:212331
First Author: Kühnisch J
Year: 2014
Journal: PLoS One
Title: Multiscale, converging defects of macro-porosity, microstructure and matrix mineralization impact long bone fragility in NF1.
Volume: 9
Issue: 1
Pages: e86115
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Publication
29032173 | J:256981
 
First Author: Tahaei SE
Year: 2018
Journal: Bone
Title: The reduced osteogenic potential of Nf1-deficient osteoprogenitors is EGFR-independent.
Volume: 106
Pages: 103-111
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29228356 | J:257000
First Author: Summers MA
Year: 2018
Journal: Hum Mol Genet
Title: Dietary intervention rescues myopathy associated with neurofibromatosis type 1.
Volume: 27
Issue: 4
Pages: 577-588
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Publication
20307317 | J:159679
 
First Author: Pemov A
Year: 2010
Journal: BMC Genomics
Title: Evidence of perturbations of cell cycle and DNA repair pathways as a consequence of human and murine NF1-haploinsufficiency.
Volume: 11
Pages: 194
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32527982 | J:291540
First Author: van Lier M
Year: 2020
Journal: J Neurosci
Title: Disruption of Critical Period Plasticity in a Mouse Model of Neurofibromatosis Type 1.
Volume: 40
Issue: 28
Pages: 5495-5509
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30542122 | J:295096
First Author: Fletcher JS
Year: 2019
Journal: Oncogene
Title: STAT3 inhibition reduces macrophage number and tumor growth in neurofibroma.
Volume: 38
Issue: 15
Pages: 2876-2884
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18984156 | J:147615
First Author: Yang FC
Year: 2008
Journal: Cell
Title: Nf1-dependent tumors require a microenvironment containing Nf1+/-- and c-kit-dependent bone marrow.
Volume: 135
Issue: 3
Pages: 437-48
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10591652 | J:58876
First Author: Cichowski K
Year: 1999
Journal: Science
Title: Mouse models of tumor development in neurofibromatosis type 1.
Volume: 286
Issue: 5447
Pages: 2172-6
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18477655 | J:152129
First Author: Nagasubramanian R
Year: 2008
Journal: Mutagenesis
Title: Survival and tumorigenesis in O6-methylguanine DNA methyltransferase-deficient mice following cyclophosphamide exposure.
Volume: 23
Issue: 5
Pages: 341-6
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Publication
18218617 | J:135289
First Author: Patrakitkomjorn S
Year: 2008
Journal: J Biol Chem
Title: Neurofibromatosis type 1 (NF1) tumor suppressor, neurofibromin, regulates the neuronal differentiation of PC12 cells via its associating protein, CRMP-2.
Volume: 283
Issue: 14
Pages: 9399-413
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26764354 | J:232645
First Author: Liu YL
Year: 2016
Journal: Blood
Title: Timing of the loss of Pten protein determines disease severity in a mouse model of myeloid malignancy.
Volume: 127
Issue: 15
Pages: 1912-22
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19477430 | J:149662
First Author: Wang Y
Year: 2009
Journal: Cancer Cell
Title: Expression of mutant p53 proteins implicates a lineage relationship between neural stem cells and malignant astrocytic glioma in a murine model.
Volume: 15
Issue: 6
Pages: 514-26
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29596064 | J:265441
First Author: Liao CP
Year: 2018
Journal: J Clin Invest
Title: Contributions of inflammation and tumor microenvironment to neurofibroma tumorigenesis.
Volume: 128
Issue: 7
Pages: 2848-2861
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9214616 | J:41126
First Author: Weiss WA
Year: 1997
Journal: EMBO J
Title: Targeted expression of MYCN causes neuroblastoma in transgenic mice.
Volume: 16
Issue: 11
Pages: 2985-95
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26002977 | J:320357
First Author: Lubeck BA
Year: 2015
Journal: J Immunol
Title: Cutting Edge: Codeletion of the Ras GTPase-Activating Proteins (RasGAPs) Neurofibromin 1 and p120 RasGAP in T Cells Results in the Development of T Cell Acute Lymphoblastic Leukemia.
Volume: 195
Issue: 1
Pages: 31-5
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25119042 | J:217077
First Author: De Raedt T
Year: 2014
Journal: Nature
Title: PRC2 loss amplifies Ras-driven transcription and confers sensitivity to BRD4-based therapies.
Volume: 514
Issue: 7521
Pages: 247-51
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18451155 | J:134611
First Author: Kwon CH
Year: 2008
Journal: Cancer Res
Title: Pten haploinsufficiency accelerates formation of high-grade astrocytomas.
Volume: 68
Issue: 9
Pages: 3286-94
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16405917 | J:104986
First Author: Boyanapalli M
Year: 2006
Journal: Biochem Biophys Res Commun
Title: Neurofibromin binds to caveolin-1 and regulates ras, FAK, and Akt.
Volume: 340
Issue: 4
Pages: 1200-8
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18316617 | J:132860
First Author: Hegedus B
Year: 2008
Journal: Cancer Res
Title: Preclinical cancer therapy in a mouse model of neurofibromatosis-1 optic glioma.
Volume: 68
Issue: 5
Pages: 1520-8
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24370551 | J:219312
First Author: Li F
Year: 2014
Journal: Circulation
Title: Neurofibromin-deficient myeloid cells are critical mediators of aneurysm formation in vivo.
Volume: 129
Issue: 11
Pages: 1213-24
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18614544 | J:138868
First Author: Hegedus B
Year: 2008
Journal: Hum Mol Genet
Title: Neurofibromin regulates somatic growth through the hypothalamic-pituitary axis.
Volume: 17
Issue: 19
Pages: 2956-66
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26965285 | J:231912
First Author: Akutagawa J
Year: 2016
Journal: Leukemia
Title: Targeting the PI3K/Akt pathway in murine MDS/MPN driven by hyperactive Ras.
Volume: 30
Issue: 6
Pages: 1335-43
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15805275 | J:97360
First Author: Dasgupta B
Year: 2005
Journal: Cancer Res
Title: Proteomic analysis reveals hyperactivation of the mammalian target of rapamycin pathway in neurofibromatosis 1-associated human and mouse brain tumors.
Volume: 65
Issue: 7
Pages: 2755-60
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15371411 | J:94906
First Author: Zhu C
Year: 2004
Journal: J Biol Chem
Title: The interferon consensus sequence-binding protein activates transcription of the gene encoding neurofibromin 1.
Volume: 279
Issue: 49
Pages: 50874-85
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Publication
31600280 | J:281157
First Author: Sutton LP
Year: 2019
Journal: PLoS Biol
Title: NF1-cAMP signaling dissociates cell type-specific contributions of striatal medium spiny neurons to reward valuation and motor control.
Volume: 17
Issue: 10
Pages: e3000477
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Publication
32471868 | J:297150
First Author: Mund JA
Year: 2020
Journal: J Biol Chem
Title: Genetic disruption of the small GTPase RAC1 prevents plexiform neurofibroma formation in mice with neurofibromatosis type 1
Volume: 295
Issue: 29
Pages: 9948-9958
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Publication
24710274 | J:221628
First Author: Hinman MN
Year: 2014
Journal: Mol Cell Biol
Title: Neurofibromatosis type 1 alternative splicing is a key regulator of Ras signaling in neurons.
Volume: 34
Issue: 12
Pages: 2188-97
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26000738 | J:224780
First Author: Mroue R
Year: 2015
Journal: PLoS Genet
Title: Monoallelic loss of the imprinted gene Grb10 promotes tumor formation in irradiated Nf1+/- mice.
Volume: 11
Issue: 5
Pages: e1005235
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23144792 | J:194861
First Author: He Y
Year: 2012
Journal: PLoS One
Title: c-Fms signaling mediates neurofibromatosis Type-1 osteoclast gain-in-functions.
Volume: 7
Issue: 11
Pages: e46900
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16648142 | J:109532
First Author: Munchhof AM
Year: 2006
Journal: Hum Mol Genet
Title: Neurofibroma-associated growth factors activate a distinct signaling network to alter the function of neurofibromin-deficient endothelial cells.
Volume: 15
Issue: 11
Pages: 1858-69
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24573885 | J:313453
First Author: Zhou P
Year: 2014
Journal: Mol Cell Biochem
Title: Down-regulated Six2 by knockdown of neurofibromin results in apoptosis of metanephric mesenchyme cells in vitro.
Volume: 390
Issue: 1-2
Pages: 205-13
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15665300 | J:95509
First Author: Dasgupta B
Year: 2005
Journal: Cancer Res
Title: Glioma formation in neurofibromatosis 1 reflects preferential activation of K-RAS in astrocytes.
Volume: 65
Issue: 1
Pages: 236-45
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Publication
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