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Search results 201 to 300 out of 1653 for Prnp

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Type Details Score
Publication
34358614 | J:346542
 
First Author: Lavigna G
Year: 2021
Journal: Neurobiol Dis
Title: Doxycycline rescues recognition memory and circadian motor rhythmicity but does not prevent terminal disease in fatal familial insomnia mice.
Volume: 158
Pages: 105455
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Allele
Prnp<tm2Cwe> | MGI:2682347
Name: prion protein; targeted mutation 2, Charles Weissmann
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Strain
MGI:5298017 | 129P2/OlaHsd-Prnp<tm2Edin>/H
Attribute String: targeted mutation, mutant strain, coisogenic
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Publication
25502554 | J:246766
First Author: Sorce S
Year: 2014
Journal: PLoS Pathog
Title: The role of the NADPH oxidase NOX2 in prion pathogenesis.
Volume: 10
Issue: 12
Pages: e1004531
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Publication
27973593 | J:253690
First Author: Donaldson DS
Year: 2016
Journal: PLoS Pathog
Title: Increased Abundance of M Cells in the Gut Epithelium Dramatically Enhances Oral Prion Disease Susceptibility.
Volume: 12
Issue: 12
Pages: e1006075
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Publication
25654651 | J:219996
   
First Author: Altmeppen HC
Year: 2015
Journal: Elife
Title: The sheddase ADAM10 is a potent modulator of prion disease.
Volume: 4
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Publication
20472884 | J:161315
First Author: Christensen HM
Year: 2010
Journal: Am J Pathol
Title: A highly toxic cellular prion protein induces a novel, nonapoptotic form of neuronal death.
Volume: 176
Issue: 6
Pages: 2695-706
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Publication
17569776 | J:142939
First Author: Dong J
Year: 2007
Journal: Am J Pathol
Title: Doppel induces degeneration of cerebellar Purkinje cells independently of Bax.
Volume: 171
Issue: 2
Pages: 599-607
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Publication
23133383 | J:195363
First Author: Falsig J
Year: 2012
Journal: PLoS Pathog
Title: Prion pathogenesis is faithfully reproduced in cerebellar organotypic slice cultures.
Volume: 8
Issue: 11
Pages: e1002985
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Publication
11823413 | J:74652
First Author: Mallucci GR
Year: 2002
Journal: EMBO J
Title: Post-natal knockout of prion protein alters hippocampal CA1 properties, but does not result in neurodegeneration.
Volume: 21
Issue: 3
Pages: 202-10
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Publication
33137126 | J:297547
First Author: Leca I
Year: 2020
Journal: PLoS Genet
Title: A proteomic survey of microtubule-associated proteins in a R402H TUBA1A mutant mouse.
Volume: 16
Issue: 11
Pages: e1009104
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Publication
20098419 | J:158343
First Author: Bremer J
Year: 2010
Journal: Nat Neurosci
Title: Axonal prion protein is required for peripheral myelin maintenance.
Volume: 13
Issue: 3
Pages: 310-8
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Publication
32673372 | J:346543
First Author: Ghirardini E
Year: 2020
Journal: PLoS Pathog
Title: Mutant prion proteins increase calcium permeability of AMPA receptors, exacerbating excitotoxicity.
Volume: 16
Issue: 7
Pages: e1008654
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Publication
25510416 | J:225676
 
First Author: Cassard H
Year: 2014
Journal: Nat Commun
Title: Evidence for zoonotic potential of ovine scrapie prions.
Volume: 5
Pages: 5821
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Publication
17947689 | J:152995
First Author: Zabel MD
Year: 2007
Journal: J Immunol
Title: Stromal complement receptor CD21/35 facilitates lymphoid prion colonization and pathogenesis.
Volume: 179
Issue: 9
Pages: 6144-52
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Publication
27975168 | J:330089
First Author: Tahir W
Year: 2018
Journal: Mol Neurobiol
Title: Molecular Alterations in the Cerebellum of Sporadic Creutzfeldt-Jakob Disease Subtypes with DJ-1 as a Key Regulator of Oxidative Stress.
Volume: 55
Issue: 1
Pages: 517-537
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Publication
23761404 | J:223991
First Author: Griffiths PC
Year: 2013
Journal: J Gen Virol
Title: Overexpression of chimaeric murine/ovine PrP (A136H154Q171) in transgenic mice facilitates transmission and differentiation of ruminant prions.
Volume: 94
Issue: Pt 11
Pages: 2577-86
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Publication
19209230 | J:183308
First Author: Rutishauser D
Year: 2009
Journal: PLoS One
Title: The comprehensive native interactome of a fully functional tagged prion protein.
Volume: 4
Issue: 2
Pages: e4446
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Publication
22163178 | J:183163
First Author: Watts JC
Year: 2011
Journal: PLoS Pathog
Title: Protease-resistant prions selectively decrease Shadoo protein.
Volume: 7
Issue: 11
Pages: e1002382
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Publication
19100703 | J:142638
First Author: Heikenwalder M
Year: 2008
Journal: Immunity
Title: Lymphotoxin-dependent prion replication in inflammatory stromal cells of granulomas.
Volume: 29
Issue: 6
Pages: 998-1008
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Publication
30174115 | J:269374
First Author: Heisler FF
Year: 2018
Journal: Neuron
Title: Muskelin Coordinates PrPC Lysosome versus Exosome Targeting and Impacts Prion Disease Progression.
Volume: 99
Issue: 6
Pages: 1155-1169.e9
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Publication
24965601 | J:339740
First Author: Vergara C
Year: 2015
Journal: Mol Neurobiol
Title: Role of PrP(C) Expression in Tau Protein Levels and Phosphorylation in Alzheimer's Disease Evolution.
Volume: 51
Issue: 3
Pages: 1206-20
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Publication
11792852 | J:73986
First Author: Prinz M
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: Lymph nodal prion replication and neuroinvasion in mice devoid of follicular dendritic cells.
Volume: 99
Issue: 2
Pages: 919-24
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Publication
23903654 | J:205018
First Author: Sonati T
Year: 2013
Journal: Nature
Title: The toxicity of antiprion antibodies is mediated by the flexible tail of the prion protein.
Volume: 501
Issue: 7465
Pages: 102-6
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Publication
9414161 | J:44933
First Author: Klein MA
Year: 1997
Journal: Nature
Title: A crucial role for B cells in neuroinvasive scrapie.
Volume: 390
Issue: 6661
Pages: 687-90
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Protein Coding Gene
MGP_CAROLIEiJ_G0024332 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0026534 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0026498 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0026473 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0026510 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0026253 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_97769 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0026955 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0025714 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0026233 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0026367 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0026331 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0026472 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0026351 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0027010 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0025450 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0025788 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0025777 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0025252 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
2890436 | J:8918
First Author: Westaway D
Year: 1987
Journal: Cell
Title: Distinct prion proteins in short and long scrapie incubation period mice.
Volume: 51
Issue: 4
Pages: 651-62
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Publication
3462700 | J:8406
First Author: Locht C
Year: 1986
Journal: Proc Natl Acad Sci U S A
Title: Molecular cloning and complete sequence of prion protein cDNA from mouse brain infected with the scrapie agent.
Volume: 83
Issue: 17
Pages: 6372-6
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Publication
9799790 | J:50880
First Author: Lee IY
Year: 1998
Journal: Genome Res
Title: Complete genomic sequence and analysis of the prion protein gene region from three mammalian species.
Volume: 8
Issue: 10
Pages: 1022-37
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Publication
3923361 | J:7876
First Author: Chesebro B
Year: 1985
Journal: Nature
Title: Identification of scrapie prion protein-specific mRNA in scrapie-infected and uninfected brain.
Volume: 315
Issue: 6017
Pages: 331-3
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Publication
8035877 | J:19448
First Author: Collinge J
Year: 1994
Journal: Nature
Title: Prion protein is necessary for normal synaptic function.
Volume: 370
Issue: 6487
Pages: 295-7
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Publication
8637886 | J:77633
First Author: Lledo PM
Year: 1996
Journal: Proc Natl Acad Sci U S A
Title: Mice deficient for prion protein exhibit normal neuronal excitability and synaptic transmission in the hippocampus.
Volume: 93
Issue: 6
Pages: 2403-7
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Publication
9837873 | J:163149
First Author: Pauly PC
Year: 1998
Journal: J Biol Chem
Title: Copper stimulates endocytosis of the prion protein.
Volume: 273
Issue: 50
Pages: 33107-10
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Publication
11756421 | J:75094
First Author: Lorenz H
Year: 2002
Journal: J Biol Chem
Title: Cellular phenotyping of secretory and nuclear prion proteins associated with inherited prion diseases.
Volume: 277
Issue: 10
Pages: 8508-16
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Publication
15161660 | J:91094
First Author: Paisley D
Year: 2004
Journal: Am J Pathol
Title: Male infertility and DNA damage in Doppel knockout and prion protein/Doppel double-knockout mice.
Volume: 164
Issue: 6
Pages: 2279-88
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Publication
19381258 | J:240271
First Author: Stevens DJ
Year: 2009
Journal: PLoS Pathog
Title: Early onset prion disease from octarepeat expansion correlates with copper binding properties.
Volume: 5
Issue: 4
Pages: e1000390
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Publication
10842180 | J:64416
First Author: Silverman GL
Year: 2000
Journal: J Biol Chem
Title: Doppel is an N-glycosylated, glycosylphosphatidylinositol-anchored protein. Expression in testis and ectopic production in the brains of Prnp(0/0) mice predisposed to Purkinje cell loss.
Volume: 275
Issue: 35
Pages: 26834-41
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Publication
16239348 | J:102929
First Author: Le Dur A
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: A newly identified type of scrapie agent can naturally infect sheep with resistant PrP genotypes.
Volume: 102
Issue: 44
Pages: 16031-6
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Publication
15767405 | J:97166
First Author: Nikles D
Year: 2005
Journal: J Virol
Title: Circumventing tolerance to the prion protein (PrP): vaccination with PrP-displaying retrovirus particles induces humoral immune responses against the native form of cellular PrP.
Volume: 79
Issue: 7
Pages: 4033-42
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Publication
11546838 | J:127850
First Author: Heppner FL
Year: 2001
Journal: Science
Title: Prevention of scrapie pathogenesis by transgenic expression of anti-prion protein antibodies.
Volume: 294
Issue: 5540
Pages: 178-82
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Publication
27440899 | J:236012
First Author: Watts JC
Year: 2016
Journal: J Virol
Title: Guinea Pig Prion Protein Supports Rapid Propagation of Bovine Spongiform Encephalopathy and Variant Creutzfeldt-Jakob Disease Prions.
Volume: 90
Issue: 21
Pages: 9558-9569
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Publication
22307640 | J:182028
First Author: You H
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Aβ neurotoxicity depends on interactions between copper ions, prion protein, and N-methyl-D-aspartate receptors.
Volume: 109
Issue: 5
Pages: 1737-42
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Publication
12664293 | J:119197
First Author: Castilla J
Year: 2003
Journal: Arch Virol
Title: Early detection of PrPres in BSE-infected bovine PrP transgenic mice.
Volume: 148
Issue: 4
Pages: 677-91
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Publication
14999066 | J:90127
First Author: Castilla J
Year: 2004
Journal: J Neurosci
Title: Different behavior toward bovine spongiform encephalopathy infection of bovine prion protein transgenic mice with one extra repeat octapeptide insert mutation.
Volume: 24
Issue: 9
Pages: 2156-64
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Publication
24608126 | J:215126
First Author: Torres JM
Year: 2014
Journal: PLoS One
Title: Elements modulating the prion species barrier and its passage consequences.
Volume: 9
Issue: 3
Pages: e89722
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Publication
23121447 | J:198089
First Author: McCulloch L
Year: 2013
Journal: Immunology
Title: Ablation of the cellular prion protein, PrPC, specifically on follicular dendritic cells has no effect on their maturation or function.
Volume: 138
Issue: 3
Pages: 246-57
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Publication
22072968 | J:183170
First Author: Friedman-Levi Y
Year: 2011
Journal: PLoS Pathog
Title: Fatal prion disease in a mouse model of genetic E200K Creutzfeldt-Jakob disease.
Volume: 7
Issue: 11
Pages: e1002350
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Publication
27891071 | J:273955
 
First Author: Fainstein N
Year: 2016
Journal: Front Neurosci
Title: Chronic Progressive Neurodegeneration in a Transgenic Mouse Model of Prion Disease.
Volume: 10
Pages: 510
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Publication
24667414 | J:211193
First Author: Friedman-Levi Y
Year: 2014
Journal: Hum Mol Genet
Title: Genetic prion disease: no role for the immune system in disease pathogenesis?
Volume: 23
Issue: 15
Pages: 4134-41
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Publication
23349890 | J:195806
First Author: Cohen E
Year: 2013
Journal: PLoS One
Title: Snord 3A: a molecular marker and modulator of prion disease progression.
Volume: 8
Issue: 1
Pages: e54433
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Publication
27365298 | J:263196
First Author: Heiss JK
Year: 2017
Journal: Cereb Cortex
Title: Early Activation of Experience-Independent Dendritic Spine Turnover in a Mouse Model of Alzheimer's Disease.
Volume: 27
Issue: 7
Pages: 3660-3674
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Publication
15354287 | J:92302
First Author: Tuzi NL
Year: 2004
Journal: Genesis
Title: Cre-loxP mediated control of PrP to study transmissible spongiform encephalopathy diseases.
Volume: 40
Issue: 1
Pages: 1-6
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Publication
31189938 | J:281589
First Author: Qin K
Year: 2019
Journal: Sci Rep
Title: "Dual Disease" TgAD/GSS mice exhibit enhanced Alzheimer's disease pathology and reveal PrPC-dependent secretion of Aβ.
Volume: 9
Issue: 1
Pages: 8524
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Publication
20445063 | J:160557
First Author: Gimbel DA
Year: 2010
Journal: J Neurosci
Title: Memory impairment in transgenic Alzheimer mice requires cellular prion protein.
Volume: 30
Issue: 18
Pages: 6367-74
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Publication
19675240 | J:151934
First Author: Yang W
Year: 2009
Journal: J Neurosci
Title: A New Transgenic Mouse Model of Gerstmann-Straussler-Scheinker Syndrome Caused by the A117V Mutation of PRNP.
Volume: 29
Issue: 32
Pages: 10072-80
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Publication
22956830 | J:221701
First Author: Cortes CJ
Year: 2012
Journal: J Neurosci
Title: Rapamycin delays disease onset and prevents PrP plaque deposition in a mouse model of Gerstmann-Sträussler-Scheinker disease.
Volume: 32
Issue: 36
Pages: 12396-405
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Publication
23637596 | J:321063
First Author: Bett C
Year: 2013
Journal: PLoS Pathog
Title: Defining the conformational features of anchorless, poorly neuroinvasive prions.
Volume: 9
Issue: 4
Pages: e1003280
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Publication
20007469 | J:156183
First Author: Bradford BM
Year: 2009
Journal: J Neurosci
Title: Dramatic reduction of PrP C level and glycosylation in peripheral nerves following PrP knock-out from Schwann cells does not prevent transmissible spongiform encephalopathy neuroinvasion.
Volume: 29
Issue: 49
Pages: 15445-54
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Publication
15163699 | J:132565
First Author: Castilla J
Year: 2004
Journal: J Neurosci
Title: Subclinical bovine spongiform encephalopathy infection in transgenic mice expressing porcine prion protein.
Volume: 24
Issue: 21
Pages: 5063-9
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Publication
20075202 | J:158379
First Author: Steinacker P
Year: 2010
Journal: Am J Pathol
Title: Neuroprotective function of cellular prion protein in a mouse model of amyotrophic lateral sclerosis.
Volume: 176
Issue: 3
Pages: 1409-20
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Publication
21123371 | J:170772
First Author: Klingeborn M
Year: 2011
Journal: J Virol
Title: Crucial role for prion protein membrane anchoring in the neuroinvasion and neural spread of prion infection.
Volume: 85
Issue: 4
Pages: 1484-94
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Publication
16632309 | J:241425
First Author: Bishop MT
Year: 2006
Journal: Lancet Neurol
Title: Predicting susceptibility and incubation time of human-to-human transmission of vCJD.
Volume: 5
Issue: 5
Pages: 393-8
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Publication
16219759 | J:105909
First Author: Cancellotti E
Year: 2005
Journal: J Biol Chem
Title: Altered glycosylated PrP proteins can have different neuronal trafficking in brain but do not acquire scrapie-like properties.
Volume: 280
Issue: 52
Pages: 42909-18
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Publication
25673720 | J:277291
First Author: Wiseman FK
Year: 2015
Journal: J Virol
Title: The glycosylation status of PrPC is a key factor in determining transmissible spongiform encephalopathy transmission between species.
Volume: 89
Issue: 9
Pages: 4738-47
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Publication
18416605 | J:136261
First Author: Tuzi NL
Year: 2008
Journal: PLoS Biol
Title: Host PrP glycosylation: a major factor determining the outcome of prion infection.
Volume: 6
Issue: 4
Pages: e100
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Publication
23395905 | J:277260
First Author: Cancellotti E
Year: 2013
Journal: EMBO J
Title: Post-translational changes to PrP alter transmissible spongiform encephalopathy strain properties.
Volume: 32
Issue: 5
Pages: 756-69
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Publication
14573822 | J:131472
First Author: Barron RM
Year: 2003
Journal: J Gen Virol
Title: Transmission of murine scrapie to P101L transgenic mice.
Volume: 84
Issue: Pt 11
Pages: 3165-72
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Publication
16621165 | J:121978
First Author: Diez M
Year: 2007
Journal: Neurobiol Aging
Title: Changes in neuropeptide expression in mice infected with prions.
Volume: 28
Issue: 5
Pages: 748-65
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Publication
15917101 | J:101713
First Author: Schwarze-Eicker K
Year: 2005
Journal: Neurobiol Aging
Title: Prion protein (PrPc) promotes beta-amyloid plaque formation.
Volume: 26
Issue: 8
Pages: 1177-82
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Publication
9636277 | J:29021
First Author: Moore RC
Year: 1995
Journal: Biotechnology (N Y)
Title: Double replacement gene targeting for the production of a series of mouse strains with different prion protein gene alterations.
Volume: 13
Issue: 9
Pages: 999-1004
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Publication
11842265 | J:103277
First Author: Tuzi NL
Year: 2002
Journal: J Gen Virol
Title: Expression of doppel in the CNS of mice does not modulate transmissible spongiform encephalopathy disease.
Volume: 83
Issue: Pt 3
Pages: 705-11
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Publication
31985492 | J:297826
First Author: Sevillano AM
Year: 2020
Journal: J Clin Invest
Title: Prion protein glycans reduce intracerebral fibril formation and spongiosis in prion disease.
Volume: 130
Issue: 3
Pages: 1350-1362
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Publication
26926995 | J:233015
First Author: Nuvolone M
Year: 2016
Journal: J Exp Med
Title: Strictly co-isogenic C57BL/6J-Prnp-/- mice: A rigorous resource for prion science.
Volume: 213
Issue: 3
Pages: 313-27
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Publication
33481951 | J:301295
First Author: Henzi A
Year: 2021
Journal: PLoS One
Title: The prion protein is not required for peripheral nerve de- and remyelination after crush injury.
Volume: 16
Issue: 1
Pages: e0245944
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Publication
31371412 | J:346575
First Author: Siberchicot C
Year: 2020
Journal: Haematologica
Title: Prion protein deficiency impairs hematopoietic stem cell determination and sensitizes myeloid progenitors to irradiation.
Volume: 105
Issue: 5
Pages: 1216-1222
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Publication
35027047 | J:339412
First Author: Matamoros-Angles A
Year: 2022
Journal: BMC Biol
Title: Analysis of co-isogenic prion protein deficient mice reveals behavioral deficits, learning impairment, and enhanced hippocampal excitability.
Volume: 20
Issue: 1
Pages: 17
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Publication
1373228 | J:472
First Author: Büeler H
Year: 1992
Journal: Nature
Title: Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein.
Volume: 356
Issue: 6370
Pages: 577-82
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Publication
23487467 | J:277328
First Author: Korom M
Year: 2013
Journal: J Virol
Title: A proautophagic antiviral role for the cellular prion protein identified by infection with a herpes simplex virus 1 ICP34.5 mutant.
Volume: 87
Issue: 10
Pages: 5882-94
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Publication
18614678 | J:137960
First Author: Prestori F
Year: 2008
Journal: J Neurosci
Title: Altered neuron excitability and synaptic plasticity in the cerebellar granular layer of juvenile prion protein knock-out mice with impaired motor control.
Volume: 28
Issue: 28
Pages: 7091-103
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Publication
22948149 | J:192133
First Author: Kang HE
Year: 2012
Journal: J Biol Chem
Title: Characterization of conformation-dependent prion protein epitopes.
Volume: 287
Issue: 44
Pages: 37219-32
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Publication
17056541 | J:140521
First Author: Martínez del Hoyo G
Year: 2006
Journal: J Immunol
Title: Prion protein expression by mouse dendritic cells is restricted to the nonplasmacytoid subsets and correlates with the maturation state.
Volume: 177
Issue: 9
Pages: 6137-42
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Publication
8100741 | J:12900
First Author: Büeler H
Year: 1993
Journal: Cell
Title: Mice devoid of PrP are resistant to scrapie.
Volume: 73
Issue: 7
Pages: 1339-47
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