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Search results 201 to 273 out of 273 for Sez6

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Type Details Score
GXD Expression  
Probe: MGI:1047250
Assay Type: RNA in situ
Annotation Date: 2013-08-27
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3271123
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5502758
Age: embryonic day 15.5
Image: 2F
Specimen Label: 2F
Detected: true
Specimen Num: 6
GXD Expression  
Probe: MGI:1047250
Assay Type: RNA in situ
Annotation Date: 2013-08-27
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3271223
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5502758
Age: embryonic day 15.5
Image: 2F
Specimen Label: 2F
Detected: true
Specimen Num: 6
GXD Expression  
Probe: MGI:1047250
Assay Type: RNA in situ
Annotation Date: 2013-08-27
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1754023
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5502758
Age: embryonic day 15.5
Image: 2F
Specimen Label: 2F
Detected: true
Specimen Num: 6
GXD Expression  
Probe: MGI:1047250
Assay Type: RNA in situ
Annotation Date: 2013-08-27
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3266523
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5502758
Age: embryonic day 15.5
Image: 2F
Specimen Label: 2F
Detected: true
Specimen Num: 6
GXD Expression
Probe: MGI:1047250
Assay Type: RNA in situ
Annotation Date: 2013-08-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691023
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:5502758
Age: embryonic day 15.5
Image: 2F
Note: Expression in medial limbic cortex extending to cortical hem.
Specimen Label: 2F
Detected: true
Specimen Num: 6
GXD Expression
Probe: MGI:1047250
Assay Type: RNA in situ
Annotation Date: 2013-08-27
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1691623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:5502758
Age: embryonic day 15.5
Image: 2F
Note: Light expression in walls of neural tube enclosing third ventricle and fourth ventricle.
Specimen Label: 2F
Detected: true
Specimen Num: 6
GXD Expression
Probe: MGI:1047250
Assay Type: RNA in situ
Annotation Date: 2013-08-27
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1689623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:5502758
Age: embryonic day 15.5
Image: 2F
Note: Light expression in walls of neural tube enclosing third ventricle and fourth ventricle.
Specimen Label: 2F
Detected: true
Specimen Num: 6
GXD Expression
Probe: MGI:1047250
Assay Type: RNA in situ
Annotation Date: 2013-08-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3271125
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:5502758
Age: embryonic day 17.5
Image: 2G
Note: Expression similar to that observed at E15.5, except for clearer definiition of expression in thicker cortical plate.
Specimen Label: 2G
Detected: true
Specimen Num: 7
GXD Expression
Probe: MGI:1047250
Assay Type: RNA in situ
Annotation Date: 2013-08-27
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3270425
Pattern: Regionally restricted
Stage: TS25
Assay Id: MGI:5502758
Age: embryonic day 17.5
Image: 2G
Note: Increased expression in subventricular zone overlying the ventricular zone in both neocortex and basal ganglia.
Specimen Label: 2G
Detected: true
Specimen Num: 7
GXD Expression  
Probe: MGI:1047250
Assay Type: RNA in situ
Annotation Date: 2013-08-27
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3271125
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:5502758
Age: embryonic day 17.5
Image: 2H
Specimen Label: 2H
Detected: true
Specimen Num: 8
GXD Expression  
Probe: MGI:1047250
Assay Type: RNA in situ
Annotation Date: 2013-08-27
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3270325
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:5502758
Age: embryonic day 17.5
Image: 2H
Specimen Label: 2H
Detected: true
Specimen Num: 8
GXD Expression  
Probe: MGI:1047250
Assay Type: RNA in situ
Annotation Date: 2013-08-27
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3270425
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:5502758
Age: embryonic day 17.5
Image: 2H
Specimen Label: 2H
Detected: true
Specimen Num: 8
GXD Expression  
Probe: MGI:1047250
Assay Type: RNA in situ
Annotation Date: 2013-08-27
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3271225
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:5502758
Age: embryonic day 17.5
Image: 2H
Specimen Label: 2H
Detected: true
Specimen Num: 8
GXD Expression    
Probe: MGI:1047250
Assay Type: RNA in situ
Annotation Date: 2013-08-27
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3270725
Stage: TS25
Assay Id: MGI:5502758
Age: embryonic day 17.5
Image: 2H
Specimen Label: 2H
Detected: false
Specimen Num: 8
GXD Expression
Probe: MGI:1047250
Assay Type: RNA in situ
Annotation Date: 2013-08-27
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3284227
Pattern: Regionally restricted
Stage: TS27
Assay Id: MGI:5502758
Age: postnatal day 1
Image: 2I
Note: Faint expression in deep layers of neocortex.
Specimen Label: 2I
Detected: true
Specimen Num: 9
GXD Expression  
Probe: MGI:1047250
Assay Type: RNA in situ
Annotation Date: 2013-08-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3524227
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:5502758
Age: postnatal day 1
Image: 2I
Specimen Label: 2I
Detected: true
Specimen Num: 9
GXD Expression  
Probe: MGI:1047250
Assay Type: RNA in situ
Annotation Date: 2013-08-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3276827
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:5502758
Age: postnatal day 1
Image: 2I
Specimen Label: 2I
Detected: true
Specimen Num: 9
GXD Expression  
Probe: MGI:1047250
Assay Type: RNA in situ
Annotation Date: 2013-08-27
Strength: Trace
Sex: Not Specified
Emaps: EMAPS:1903727
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:5502758
Age: postnatal day 1
Image: 2I
Specimen Label: 2I
Detected: true
Specimen Num: 9
GXD Expression  
Probe: MGI:1047250
Assay Type: RNA in situ
Annotation Date: 2013-08-27
Strength: Trace
Sex: Not Specified
Emaps: EMAPS:3277027
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:5502758
Age: postnatal day 1
Image: 2I
Specimen Label: 2I
Detected: true
Specimen Num: 9
GXD Expression  
Probe: MGI:1047250
Assay Type: RNA in situ
Annotation Date: 2013-08-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3521927
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:5502758
Age: postnatal day 1
Image: 2J
Specimen Label: 2J
Detected: true
Specimen Num: 10
GXD Expression  
Probe: MGI:1047250
Assay Type: RNA in situ
Annotation Date: 2013-08-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3522327
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:5502758
Age: postnatal day 1
Image: 2J
Specimen Label: 2J
Detected: true
Specimen Num: 10
GXD Expression  
Probe: MGI:1047250
Assay Type: RNA in situ
Annotation Date: 2013-08-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3276828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5502758
Age: postnatal adult
Image: 2K
Specimen Label: 2K
Detected: true
Specimen Num: 11
GXD Expression    
Probe: MGI:1047250
Assay Type: RNA in situ
Annotation Date: 2013-08-27
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3284228
Stage: TS28
Assay Id: MGI:5502758
Age: postnatal adult
Image: 2K
Specimen Label: 2K
Detected: false
Specimen Num: 11
GXD Expression
Probe: MGI:6478287
Assay Type: Immunohistochemistry
Annotation Date: 2020-12-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3574128
Pattern: Non-Uniform
Stage: TS28
Assay Id: MGI:6478297
Age: postnatal adult
Image: 2A/B
Note: Fine puntate staining was observed extending into the inner plexiform layer along apical dendrites of the labeled neurons in the ganglion cell layer.
Specimen Label: 2A/B
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:6478287
Assay Type: Immunohistochemistry
Annotation Date: 2020-12-08
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1716828
Stage: TS28
Assay Id: MGI:6478297
Age: postnatal adult
Image: 2C/D
Note: Low level diffuse non-specific staining was observed in ganglion cells, the inner and outer plexiform layers and photoreceptor outer segments.
Specimen Label: 2C/D
Detected: false
Specimen Num: 2
GXD Expression
Probe: MGI:6478287
Assay Type: Immunohistochemistry
Annotation Date: 2020-12-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1915528
Pattern: Non-Uniform
Stage: TS28
Assay Id: MGI:6478297
Age: postnatal adult
Image: 2E
Note: Strongest immunoreactivity was observed in two rows of cells adjacent to the inner plexiform layer. Signal was concentrated strongly within a discrete perinuclear bright spot. More diffuse cytoplasmic staining was also observed in amacrine cells. Staining was noted in bipolar cell and horizontal cell somata in the outer part of the inner nuclear layer.
Specimen Label: 2E
Detected: true
Specimen Num: 3
GXD Expression
Probe: MGI:6478287
Assay Type: Immunohistochemistry
Annotation Date: 2020-12-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3573928
Pattern: Non-Uniform
Stage: TS28
Assay Id: MGI:6478297
Age: postnatal adult
Image: 2F
Note: Expression was detected in an alpha or A1 ganglion cell.
Specimen Label: 2F
Detected: true
Specimen Num: 4
GXD Expression
Probe: MGI:6478287
Assay Type: Immunohistochemistry
Annotation Date: 2020-12-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1915528
Pattern: Non-Uniform
Stage: TS28
Assay Id: MGI:6478297
Age: postnatal adult
Image: 2A/B
Note: Expression was particularly prominent in the amacrine cells of the inner nuclear layer. Strongest immunoreactivity was observed in two rows of cells adjacent to the inner plexiform layer.
Specimen Label: 2A/B
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:6478287
Assay Type: Immunohistochemistry
Annotation Date: 2020-12-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1915528
Pattern: Non-Uniform
Stage: TS28
Assay Id: MGI:6478297
Age: postnatal adult
Image: 2F
Note: Expression was noted in a horizontal cell. Strongest immunoreactivity was observed in two rows of cells adjacent to the inner plexiform layer.
Specimen Label: 2F
Detected: true
Specimen Num: 4
GXD Expression
Probe: MGI:6478287
Assay Type: Immunohistochemistry
Annotation Date: 2020-12-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3573928
Pattern: Non-Uniform
Stage: TS28
Assay Id: MGI:6478297
Age: postnatal adult
Image: 2A/B
Note: Immunostained cells were observed in the ganglion cell layer (many of which are likely to be displaced amacrines). Immunreactivity was observed in bright puncta, frequently positioned adjacent to the nucleus and the apical dendrite.
Specimen Label: 2A/B
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:6478287
Assay Type: Immunohistochemistry
Annotation Date: 2020-12-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3574428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6478297
Age: postnatal adult
Image: 2A/B
Note: Bipolar cell apical dentrites were positively stained.
Specimen Label: 2A/B
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:6478287
Assay Type: Immunohistochemistry
Annotation Date: 2020-12-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3574428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6478297
Age: postnatal adult
Image: 2E
Note: Bipolar cell apical dentrites were positively stained.
Specimen Label: 2E
Detected: true
Specimen Num: 3
GXD Expression
Probe: MGI:6478287
Assay Type: Immunohistochemistry
Annotation Date: 2020-12-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716828
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6478914
Age: postnatal adult
Image: 4F
Note: A high degree of co-labelling was noted with Chat.
Specimen Label: 4F
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:6183135
Assay Type: RNA in situ
Annotation Date: 2023-11-28
Strength: Present
Sex: Male
Emaps: EMAPS:3583128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7561851
Age: postnatal day 56
Image: S3
Specimen Label: S3
Detected: true
Specimen Num: 1
Publication
First Author: Gunnersen JM
Year: 2009
Journal: PLoS One
Title: Seizure-related gene 6 (Sez-6) in amacrine cells of the rodent retina and the consequence of gene deletion.
Volume: 4
Issue: 8
Pages: e6546
Publication
First Author: Kajiwara K
Year: 1996
Journal: Biochem Biophys Res Commun
Title: Molecular characterization of seizure-related genes isolated by differential screening.
Volume: 219
Issue: 3
Pages: 795-9
Publication
First Author: Nehls M
Year: 1995
Journal: Mamm Genome
Title: YAC/P1 contigs defining the location of 56 microsatellite markers and several genes across a 3.4-cM interval on mouse chromosome 11.
Volume: 6
Issue: 5
Pages: 321-31
Publication
First Author: Miyazaki T
Year: 2006
Journal: FEBS Lett
Title: Disturbance of cerebellar synaptic maturation in mutant mice lacking BSRPs, a novel brain-specific receptor-like protein family.
Volume: 580
Issue: 17
Pages: 4057-64
Publication
First Author: Lumayag S
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Inactivation of the microRNA-183/96/182 cluster results in syndromic retinal degeneration.
Volume: 110
Issue: 6
Pages: E507-16
Publication      
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
Publication
First Author: Shimogori T
Year: 2010
Journal: Nat Neurosci
Title: A genomic atlas of mouse hypothalamic development.
Volume: 13
Issue: 6
Pages: 767-75
Publication
First Author: Miller JA
Year: 2013
Journal: Development
Title: Conserved molecular signatures of neurogenesis in the hippocampal subgranular zone of rodents and primates.
Volume: 140
Issue: 22
Pages: 4633-44
Publication
First Author: Blackshaw S
Year: 2004
Journal: PLoS Biol
Title: Genomic analysis of mouse retinal development.
Volume: 2
Issue: 9
Pages: E247
Publication      
First Author: MGI and IMPC
Year: 2017
Journal: MGI Direct Data Submission
Title: MGI Curation of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Mouse Synonym Curation
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Function or Process or Component Unknown following Literature Review
Publication      
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
Publication
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Publication
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
Publication        
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Allele
Name: seizure related gene 6; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
GXD Expression
Probe: MGI:6478288
Assay Type: Immunohistochemistry
Annotation Date: 2020-12-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6478912
Age: postnatal adult
Image: 4F
Note: A high degree of co-labelling with Sez6 was noted.
Specimen Label: 4F
Detected: true
Specimen Num: 1
Strain
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
Publication
First Author: Zhu K
Year: 2018
Journal: Biol Psychiatry
Title: Beta-Site Amyloid Precursor Protein Cleaving Enzyme 1 Inhibition Impairs Synaptic Plasticity via Seizure Protein 6.
Volume: 83
Issue: 5
Pages: 428-437