Type |
Details |
Score |
Publication |
First Author: |
Claes AK |
Year: |
2014 |
Journal: |
PLoS One |
Title: |
Salmonella enterica serovar Typhimurium ΔmsbB triggers exacerbated inflammation in Nod2 deficient mice. |
Volume: |
9 |
Issue: |
11 |
Pages: |
e113645 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kawakami A |
Year: |
2008 |
Journal: |
Circ Res |
Title: |
Toll-like receptor 2 mediates apolipoprotein CIII-induced monocyte activation. |
Volume: |
103 |
Issue: |
12 |
Pages: |
1402-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Caricilli AM |
Year: |
2011 |
Journal: |
PLoS Biol |
Title: |
Gut microbiota is a key modulator of insulin resistance in TLR 2 knockout mice. |
Volume: |
9 |
Issue: |
12 |
Pages: |
e1001212 |
|
•
•
•
•
•
|
Publication |
First Author: |
Muxel SM |
Year: |
2018 |
Journal: |
Front Immunol |
Title: |
Toll-Like Receptor and miRNA-let-7e Expression Alter the Inflammatory Response in Leishmania amazonensis-Infected Macrophages. |
Volume: |
9 |
|
Pages: |
2792 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hochhauser E |
Year: |
2013 |
Journal: |
PLoS One |
Title: |
Bone marrow and nonbone marrow Toll like receptor 4 regulate acute hepatic injury induced by endotoxemia. |
Volume: |
8 |
Issue: |
8 |
Pages: |
e73041 |
|
•
•
•
•
•
|
Publication |
First Author: |
Iyoda T |
Year: |
2014 |
Journal: |
J Immunol |
Title: |
A novel mechanism underlying the basic defensive response of macrophages against Mycobacterium infection. |
Volume: |
192 |
Issue: |
9 |
Pages: |
4254-62 |
|
•
•
•
•
•
|
Publication |
First Author: |
Blanchet C |
Year: |
2014 |
Journal: |
PLoS One |
Title: |
Protective or deleterious role of scavenger receptors SR-A and CD36 on host resistance to Staphylococcus aureus depends on the site of infection. |
Volume: |
9 |
Issue: |
1 |
Pages: |
e87927 |
|
•
•
•
•
•
|
Publication |
First Author: |
Stivers NS |
Year: |
2017 |
Journal: |
Exp Neurol |
Title: |
The toll-like receptor 2 agonist Pam3CSK4 is neuroprotective after spinal cord injury. |
Volume: |
294 |
|
Pages: |
1-11 |
|
•
•
•
•
•
|
Publication |
First Author: |
Miraglia MC |
Year: |
2016 |
Journal: |
J Immunol |
Title: |
Glial Cell-Elicited Activation of Brain Microvasculature in Response to Brucella abortus Infection Requires ASC Inflammasome-Dependent IL-1β Production. |
Volume: |
196 |
Issue: |
9 |
Pages: |
3794-805 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang X |
Year: |
2021 |
Journal: |
Mol Immunol |
Title: |
Host defense against Neospora caninum infection via IL-12p40 production through TLR2/TLR3-AKT-ERK signaling pathway in C57BL/6 mice. |
Volume: |
139 |
|
Pages: |
140-152 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cole TS |
Year: |
2012 |
Journal: |
Immunol Lett |
Title: |
IRAK-M modulates expression of IL-10 and cell surface markers CD80 and MHC II after bacterial re-stimulation of tolerized dendritic cells. |
Volume: |
144 |
Issue: |
1-2 |
Pages: |
49-59 |
|
•
•
•
•
•
|
Publication |
First Author: |
Liu YH |
Year: |
2018 |
Journal: |
Front Cell Infect Microbiol |
Title: |
The ATP-P2X7 Signaling Axis Is an Essential Sentinel for Intracellular Clostridium difficile Pathogen-Induced Inflammasome Activation. |
Volume: |
8 |
|
Pages: |
84 |
|
•
•
•
•
•
|
Publication |
First Author: |
Antoni AC |
Year: |
2022 |
Journal: |
Front Immunol |
Title: |
TLR2-induced CD8(+) T-cell deactivation shapes dendritic cell differentiation in the bone marrow during sepsis. |
Volume: |
13 |
|
Pages: |
945409 |
|
•
•
•
•
•
|
Publication |
First Author: |
Takeuchi O |
Year: |
1999 |
Journal: |
Gene |
Title: |
TLR6: A novel member of an expanding toll-like receptor family. |
Volume: |
231 |
Issue: |
1-2 |
Pages: |
59-65 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
274
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
102
|
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
270
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
205
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
274
|
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Horng T |
Year: |
2001 |
Journal: |
Nat Immunol |
Title: |
TIRAP: an adapter molecule in the Toll signaling pathway. |
Volume: |
2 |
Issue: |
9 |
Pages: |
835-41 |
|
•
•
•
•
•
|
Publication |
First Author: |
Liu B |
Year: |
2006 |
Journal: |
J Immunol |
Title: |
TLR4 up-regulation at protein or gene level is pathogenic for lupus-like autoimmune disease. |
Volume: |
177 |
Issue: |
10 |
Pages: |
6880-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jeyaseelan S |
Year: |
2006 |
Journal: |
J Immunol |
Title: |
Toll/IL-1R domain-containing adaptor protein (TIRAP) is a critical mediator of antibacterial defense in the lung against Klebsiella pneumoniae but not Pseudomonas aeruginosa. |
Volume: |
177 |
Issue: |
1 |
Pages: |
538-47 |
|
•
•
•
•
•
|
Publication |
First Author: |
Horng T |
Year: |
2002 |
Journal: |
Nature |
Title: |
The adaptor molecule TIRAP provides signalling specificity for Toll-like receptors. |
Volume: |
420 |
Issue: |
6913 |
Pages: |
329-33 |
|
•
•
•
•
•
|
Publication |
First Author: |
Evans S |
Year: |
2020 |
Journal: |
Sci Rep |
Title: |
Ischemia reperfusion injury provokes adverse left ventricular remodeling in dysferlin-deficient hearts through a pathway that involves TIRAP dependent signaling. |
Volume: |
10 |
Issue: |
1 |
Pages: |
14129 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yamamoto M |
Year: |
2004 |
Journal: |
Mol Immunol |
Title: |
TIR domain-containing adaptors define the specificity of TLR signaling. |
Volume: |
40 |
Issue: |
12 |
Pages: |
861-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Semaan N |
Year: |
2008 |
Journal: |
J Immunol |
Title: |
Etk/BMX, a Btk family tyrosine kinase, and Mal contribute to the cross-talk between MyD88 and FAK pathways. |
Volume: |
180 |
Issue: |
5 |
Pages: |
3485-91 |
|
•
•
•
•
•
|
Publication |
First Author: |
Brown GT |
Year: |
2011 |
Journal: |
J Immunol |
Title: |
Lipopolysaccharide signaling without a nucleus: kinase cascades stimulate platelet shedding of proinflammatory IL-1β-rich microparticles. |
Volume: |
186 |
Issue: |
9 |
Pages: |
5489-96 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bockstahler M |
Year: |
2020 |
Journal: |
Circulation |
Title: |
Heart-Specific Immune Responses in an Animal Model of Autoimmune-Related Myocarditis Mitigated by an Immunoproteasome Inhibitor and Genetic Ablation. |
Volume: |
141 |
Issue: |
23 |
Pages: |
1885-1902 |
|
•
•
•
•
•
|
Publication |
First Author: |
Steinberg N |
Year: |
2023 |
Journal: |
J Neuroinflammation |
Title: |
Naïve Huntington's disease microglia mount a normal response to inflammatory stimuli but display a partially impaired development of innate immune tolerance that can be counteracted by ganglioside GM1. |
Volume: |
20 |
Issue: |
1 |
Pages: |
276 |
|
•
•
•
•
•
|
Publication |
First Author: |
Rayasam A |
Year: |
2020 |
Journal: |
J Neurosci |
Title: |
Neonatal Stroke and TLR1/2 Ligand Recruit Myeloid Cells through the Choroid Plexus in a CX3CR1-CCR2- and Context-Specific Manner. |
Volume: |
40 |
Issue: |
19 |
Pages: |
3849-3861 |
|
•
•
•
•
•
|
Publication |
First Author: |
Li F |
Year: |
2015 |
Journal: |
J Neurochem |
Title: |
Lack of the scavenger receptor CD36 alters microglial phenotypes after neonatal stroke. |
Volume: |
135 |
Issue: |
3 |
Pages: |
445-52 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bröker K |
Year: |
2018 |
Journal: |
Front Immunol |
Title: |
A Novel Role for C5a in B-1 Cell Homeostasis. |
Volume: |
9 |
|
Pages: |
258 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shen Z |
Year: |
2022 |
Journal: |
EBioMedicine |
Title: |
Roseburia intestinalis stimulates TLR5-dependent intestinal immunity against Crohn's disease. |
Volume: |
85 |
|
Pages: |
104285 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
244
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
199
|
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Fitzgerald KA |
Year: |
2001 |
Journal: |
Nature |
Title: |
Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction. |
Volume: |
413 |
Issue: |
6851 |
Pages: |
78-83 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bonham KS |
Year: |
2014 |
Journal: |
Cell |
Title: |
A promiscuous lipid-binding protein diversifies the subcellular sites of toll-like receptor signal transduction. |
Volume: |
156 |
Issue: |
4 |
Pages: |
705-16 |
|
•
•
•
•
•
|
Publication |
First Author: |
Fremond CM |
Year: |
2007 |
Journal: |
J Immunol |
Title: |
IL-1 receptor-mediated signal is an essential component of MyD88-dependent innate response to Mycobacterium tuberculosis infection. |
Volume: |
179 |
Issue: |
2 |
Pages: |
1178-89 |
|
•
•
•
•
•
|
Publication |
First Author: |
Figgett WA |
Year: |
2013 |
Journal: |
Immunity |
Title: |
The TACI receptor regulates T-cell-independent marginal zone B cell responses through innate activation-induced cell death. |
Volume: |
39 |
Issue: |
3 |
Pages: |
573-83 |
|
•
•
•
•
•
|
Publication |
First Author: |
Li Z |
Year: |
2011 |
Journal: |
PLoS One |
Title: |
Hyaluronan signaling during ozone-induced lung injury requires TLR4, MyD88, and TIRAP. |
Volume: |
6 |
Issue: |
11 |
Pages: |
e27137 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lebeis SL |
Year: |
2007 |
Journal: |
J Immunol |
Title: |
TLR signaling mediated by MyD88 is required for a protective innate immune response by neutrophils to Citrobacter rodentium. |
Volume: |
179 |
Issue: |
1 |
Pages: |
566-77 |
|
•
•
•
•
•
|
Publication |
First Author: |
Siednienko J |
Year: |
2010 |
Journal: |
Eur J Immunol |
Title: |
TLR3-mediated IFN-β gene induction is negatively regulated by the TLR adaptor MyD88 adaptor-like. |
Volume: |
40 |
Issue: |
11 |
Pages: |
3150-60 |
|
•
•
•
•
•
|
Publication |
First Author: |
Inoue A |
Year: |
2016 |
Journal: |
Sci Rep |
Title: |
TIARP attenuates autoantibody-mediated arthritis via the suppression of neutrophil migration by reducing CXCL2/CXCR2 and IL-6 expression. |
Volume: |
6 |
|
Pages: |
38684 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
795
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
795
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
806
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
806
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
727
|
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
806
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
795
|
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Troutman TD |
Year: |
2012 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Role for B-cell adapter for PI3K (BCAP) as a signaling adapter linking Toll-like receptors (TLRs) to serine/threonine kinases PI3K/Akt. |
Volume: |
109 |
Issue: |
1 |
Pages: |
273-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Fitzgerald KA |
Year: |
2003 |
Journal: |
J Exp Med |
Title: |
LPS-TLR4 signaling to IRF-3/7 and NF-kappaB involves the toll adapters TRAM and TRIF. |
Volume: |
198 |
Issue: |
7 |
Pages: |
1043-55 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kagan JC |
Year: |
2008 |
Journal: |
Nat Immunol |
Title: |
TRAM couples endocytosis of Toll-like receptor 4 to the induction of interferon-beta. |
Volume: |
9 |
Issue: |
4 |
Pages: |
361-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ma J |
Year: |
2013 |
Journal: |
Sci Signal |
Title: |
The TNF family member 4-1BBL sustains inflammation by interacting with TLR signaling components during late-phase activation. |
Volume: |
6 |
Issue: |
295 |
Pages: |
ra87 |
|
•
•
•
•
•
|
Publication |
First Author: |
Greenhill CJ |
Year: |
2011 |
Journal: |
J Immunol |
Title: |
IL-6 trans-signaling modulates TLR4-dependent inflammatory responses via STAT3. |
Volume: |
186 |
Issue: |
2 |
Pages: |
1199-208 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sun Y |
Year: |
2010 |
Journal: |
J Immunol |
Title: |
TLR4 and TLR5 on corneal macrophages regulate Pseudomonas aeruginosa keratitis by signaling through MyD88-dependent and -independent pathways. |
Volume: |
185 |
Issue: |
7 |
Pages: |
4272-83 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhou R |
Year: |
2012 |
Journal: |
Invest Ophthalmol Vis Sci |
Title: |
Innate immune regulation of Serratia marcescens-induced corneal inflammation and infection. |
Volume: |
53 |
Issue: |
11 |
Pages: |
7382-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cook P |
Year: |
2007 |
Journal: |
Immunology |
Title: |
Salmonella-induced SipB-independent cell death requires Toll-like receptor-4 signalling via the adapter proteins Tram and Trif. |
Volume: |
122 |
Issue: |
2 |
Pages: |
222-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Togbe D |
Year: |
2006 |
Journal: |
Lab Invest |
Title: |
Nonredundant roles of TIRAP and MyD88 in airway response to endotoxin, independent of TRIF, IL-1 and IL-18 pathways. |
Volume: |
86 |
Issue: |
11 |
Pages: |
1126-35 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lundberg AM |
Year: |
2013 |
Journal: |
Cardiovasc Res |
Title: |
Toll-like receptor 3 and 4 signalling through the TRIF and TRAM adaptors in haematopoietic cells promotes atherosclerosis. |
Volume: |
99 |
Issue: |
2 |
Pages: |
364-73 |
|
•
•
•
•
•
|
Publication |
First Author: |
Georgel P |
Year: |
2007 |
Journal: |
Virology |
Title: |
Vesicular stomatitis virus glycoprotein G activates a specific antiviral Toll-like receptor 4-dependent pathway. |
Volume: |
362 |
Issue: |
2 |
Pages: |
304-13 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wei B |
Year: |
2008 |
Journal: |
Eur J Immunol |
Title: |
Resident enteric microbiota and CD8+ T cells shape the abundance of marginal zone B cells. |
Volume: |
38 |
Issue: |
12 |
Pages: |
3411-25 |
|
•
•
•
•
•
|
Publication |
First Author: |
Layoun A |
Year: |
2012 |
Journal: |
Am J Pathol |
Title: |
Toll-like receptor signal adaptor protein MyD88 is required for sustained endotoxin-induced acute hypoferremic response in mice. |
Volume: |
180 |
Issue: |
6 |
Pages: |
2340-50 |
|
•
•
•
•
•
|
Publication |
First Author: |
Dixit E |
Year: |
2010 |
Journal: |
Cell |
Title: |
Peroxisomes are signaling platforms for antiviral innate immunity. |
Volume: |
141 |
Issue: |
4 |
Pages: |
668-81 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gopal A |
Year: |
2022 |
Journal: |
J Exp Med |
Title: |
TIRAP drives myelosuppression through an Ifnγ-Hmgb1 axis that disrupts the endothelial niche in mice. |
Volume: |
219 |
Issue: |
3 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Young GR |
Year: |
2012 |
Journal: |
Nature |
Title: |
Resurrection of endogenous retroviruses in antibody-deficient mice. |
Volume: |
491 |
Issue: |
7426 |
Pages: |
774-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Rothenfusser S |
Year: |
2005 |
Journal: |
J Immunol |
Title: |
The RNA helicase Lgp2 inhibits TLR-independent sensing of viral replication by retinoic acid-inducible gene-I. |
Volume: |
175 |
Issue: |
8 |
Pages: |
5260-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang SS |
Year: |
2007 |
Journal: |
Arterioscler Thromb Vasc Biol |
Title: |
Mapping, genetic isolation, and characterization of genetic loci that determine resistance to atherosclerosis in C3H mice. |
Volume: |
27 |
Issue: |
12 |
Pages: |
2671-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Miao EA |
Year: |
2010 |
Journal: |
Nat Immunol |
Title: |
Caspase-1-induced pyroptosis is an innate immune effector mechanism against intracellular bacteria. |
Volume: |
11 |
Issue: |
12 |
Pages: |
1136-42 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bonilla DL |
Year: |
2013 |
Journal: |
Immunity |
Title: |
Autophagy regulates phagocytosis by modulating the expression of scavenger receptors. |
Volume: |
39 |
Issue: |
3 |
Pages: |
537-47 |
|
•
•
•
•
•
|
Publication |
First Author: |
Weiss G |
Year: |
2012 |
Journal: |
J Immunol |
Title: |
MyD88 drives the IFN-β response to Lactobacillus acidophilus in dendritic cells through a mechanism involving IRF1, IRF3, and IRF7. |
Volume: |
189 |
Issue: |
6 |
Pages: |
2860-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Haiming Tang, Dustin Ebert, Matthias Blum, Robert Finn, Paul Thomas |
Year: |
2023 |
|
Title: |
TreeGrafter-generated GO annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations for FANTOM2 data |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2003 |
|
Title: |
MGI Sequence Curation Reference |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Zambrowicz BP |
Year: |
2003 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. |
Volume: |
100 |
Issue: |
24 |
Pages: |
14109-14 |
|
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•
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Publication |
First Author: |
Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI) |
Year: |
2008 |
Journal: |
Database Download |
Title: |
Mouse Gene Trap Data Load from dbGSS |
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Publication |
First Author: |
UniProt-GOA |
Year: |
2012 |
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Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
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Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations |
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