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Search results 2101 to 2200 out of 2339 for Erbb2

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Type Details Score
Publication
20090754 | J:156591
First Author: Bienvenu F
Year: 2010
Journal: Nature
Title: Transcriptional role of cyclin D1 in development revealed by a genetic-proteomic screen.
Volume: 463
Issue: 7279
Pages: 374-8
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Publication
30526553 | J:308845
First Author: Homer-Bouthiette C
Year: 2018
Journal: BMC Cancer
Title: Deletion of the murine ortholog of the 8q24 gene desert has anti-cancer effects in transgenic mammary cancer models.
Volume: 18
Issue: 1
Pages: 1233
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Publication
36614200 | J:332518
 
First Author: Manna PR
Year: 2023
Journal: Int J Mol Sci
Title: Expression and Function of StAR in Cancerous and Non-Cancerous Human and Mouse Breast Tissues: New Insights into Diagnosis and Treatment of Hormone-Sensitive Breast Cancer.
Volume: 24
Issue: 1
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Publication
15888345 | J:100623
First Author: Shen Q
Year: 2005
Journal: Mutat Res
Title: Transgenic mouse models for the prevention of breast cancer.
Volume: 576
Issue: 1-2
Pages: 93-110
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Strain
MGI:7550828 | FVB/N-Tg(MMTV-rtTA)1Lach Tg(tetO-ERBB2)#Jjz/Jjz
Attribute String: coisogenic, mutant strain, transgenic
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Publication
26977878 | J:231766
First Author: Goel S
Year: 2016
Journal: Cancer Cell
Title: Overcoming Therapeutic Resistance in HER2-Positive Breast Cancers with CDK4/6 Inhibitors.
Volume: 29
Issue: 3
Pages: 255-69
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Publication
20860838 | J:183958
First Author: McHenry PR
Year: 2010
Journal: Breast Cancer Res
Title: P190B RhoGAP has pro-tumorigenic functions during MMTV-Neu mammary tumorigenesis and metastasis.
Volume: 12
Issue: 5
Pages: R73
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Strain
MGI:4839532 | FVB.Cg-Tg(CAG-Has2)99Nita Tg(MMTV-cre)4Mam Tg(MMTVneu)202Mul
Attribute String: congenic, mutant strain, transgenic
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Publication
34704597 | J:315698
First Author: Ramachandran S
Year: 2021
Journal: Biochem J
Title: Expression and function of SLC38A5, an amino acid-coupled Na+/H+ exchanger, in triple-negative breast cancer and its relevance to macropinocytosis.
Volume: 478
Issue: 21
Pages: 3957-3976
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Publication
17322391 | J:118655
First Author: Koyama H
Year: 2007
Journal: Am J Pathol
Title: Hyperproduction of hyaluronan in neu-induced mammary tumor accelerates angiogenesis through stromal cell recruitment: possible involvement of versican/PG-M.
Volume: 170
Issue: 3
Pages: 1086-99
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Publication
23830207 | J:199994
First Author: Song SJ
Year: 2013
Journal: Cell
Title: MicroRNA-antagonism regulates breast cancer stemness and metastasis via TET-family-dependent chromatin remodeling.
Volume: 154
Issue: 2
Pages: 311-324
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Publication
18780892 | J:152332
First Author: Ciraolo E
Year: 2008
Journal: Sci Signal
Title: Phosphoinositide 3-kinase p110beta activity: key role in metabolism and mammary gland cancer but not development.
Volume: 1
Issue: 36
Pages: ra3
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Publication
21479246 | J:171443
First Author: Goldman SJ
Year: 2011
Journal: PLoS One
Title: Use of the ODD-luciferase transgene for the non-invasive imaging of spontaneous tumors in mice.
Volume: 6
Issue: 3
Pages: e18269
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Publication
32061755 | J:285838
 
First Author: Achyut BR
Year: 2020
Journal: Cancer Lett
Title: Oncoprotein GT198 vaccination delays tumor growth in MMTV-PyMT mice.
Volume: 476
Pages: 57-66
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Publication
26893478 | J:231694
First Author: Zhao Z
Year: 2016
Journal: Cancer Res
Title: In Vivo Visualization and Characterization of Epithelial-Mesenchymal Transition in Breast Tumors.
Volume: 76
Issue: 8
Pages: 2094-2104
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Publication
35281099 | J:321835
 
First Author: Sarrio D
Year: 2022
Journal: Front Cell Dev Biol
Title: Gasdermin-B Pro-Tumor Function in Novel Knock-in Mouse Models Depends on the in vivo Biological Context.
Volume: 10
Pages: 813929
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Publication
26173258 | J:226105
First Author: Babu E
Year: 2015
Journal: Biochem J
Title: Deletion of the amino acid transporter Slc6a14 suppresses tumour growth in spontaneous mouse models of breast cancer.
Volume: 469
Issue: 1
Pages: 17-23
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Publication
28300085 | J:244900
 
First Author: Grasso S
Year: 2017
Journal: Nat Commun
Title: The scaffold protein p140Cap limits ERBB2-mediated breast cancer progression interfering with Rac GTPase-controlled circuitries.
Volume: 8
Pages: 14797
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Publication
20129248 | J:156929
First Author: Jeselsohn R
Year: 2010
Journal: Cancer Cell
Title: Cyclin D1 kinase activity is required for the self-renewal of mammary stem and progenitor cells that are targets of MMTV-ErbB2 tumorigenesis.
Volume: 17
Issue: 1
Pages: 65-76
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Publication
21482677 | J:173655
First Author: Meyer DS
Year: 2011
Journal: Cancer Res
Title: Luminal expression of PIK3CA mutant H1047R in the mammary gland induces heterogeneous tumors.
Volume: 71
Issue: 13
Pages: 4344-51
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Publication
31267692 | J:290544
First Author: Uribesalgo I
Year: 2019
Journal: EMBO Mol Med
Title: Apelin inhibition prevents resistance and metastasis associated with anti-angiogenic therapy.
Volume: 11
Issue: 8
Pages: e9266
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Publication
22632973 | J:186169
First Author: Chan CH
Year: 2012
Journal: Cell
Title: The Skp2-SCF E3 ligase regulates Akt ubiquitination, glycolysis, herceptin sensitivity, and tumorigenesis.
Volume: 149
Issue: 5
Pages: 1098-111
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Publication
12808151 | J:84434
First Author: Siegel PM
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Transforming growth factor beta signaling impairs Neu-induced mammary tumorigenesis while promoting pulmonary metastasis.
Volume: 100
Issue: 14
Pages: 8430-5
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Publication
21610252 | J:185994
First Author: Wen HC
Year: 2011
Journal: Sci Signal
Title: p38α Signaling Induces Anoikis and Lumen Formation During Mammary Morphogenesis.
Volume: 4
Issue: 174
Pages: ra34
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Publication
22006184 | J:320500
First Author: Nair HB
Year: 2012
Journal: Horm Cancer
Title: Estrogen receptor-beta mediates the protective effects of aromatase induction in the MMTV-Her-2/neu x aromatase double transgenic mice.
Volume: 3
Issue: 1-2
Pages: 26-36
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Publication
18592271 | J:142164
First Author: Strumane K
Year: 2009
Journal: J Cancer Res Clin Oncol
Title: Tiam1-deficiency impairs mammary tumor formation in MMTV-c-neu but not in MMTV-c-myc mice.
Volume: 135
Issue: 1
Pages: 69-80
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Publication
9418856 | J:78608
First Author: Barrington RE
Year: 1998
Journal: Mol Cell Biol
Title: A farnesyltransferase inhibitor induces tumor regression in transgenic mice harboring multiple oncogenic mutations by mediating alterations in both cell cycle control and apoptosis.
Volume: 18
Issue: 1
Pages: 85-92
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Publication
31825825 | J:292698
First Author: Feng WW
Year: 2019
Journal: Cell Rep
Title: CD36-Mediated Metabolic Rewiring of Breast Cancer Cells Promotes Resistance to HER2-Targeted Therapies.
Volume: 29
Issue: 11
Pages: 3405-3420.e5
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Genotype
Genotype
Symbol: Akt2/Akt2 Tg(MMTV-Erbb2)NK1Mul/Tg(MMTV-Erbb2)NK1Mul
Background: involves: 129 * C57BL/6 * FVB/N
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Esr1/Esr1 Tg(MMTV-Erbb2)NK1Mul/?
Background: involves: 129P2/OlaHsd * C57BL/6J * FVB/N
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(CAG-Has2)99Nita/? Tg(MMTV-cre)4Mam/? Tg(MMTVneu)202Mul/?
Background: FVB.Cg-Tg(CAG-Has2)99Nita Tg(MMTV-cre)4Mam Tg(MMTVneu)202Mul
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Erbb3/Erbb3<+> Tg(MMTV-Erbb2*)NDL2-5Mul/?
Background: involves: 129P2/OlaHsd * C57BL/6 * FVB/N
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Erbb3/Erbb3 Tg(MMTV-Erbb2*)NDL2-5Mul/?
Background: involves: 129P2/OlaHsd * C57BL/6 * FVB/N
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Ccnd1/Ccnd1 Tg(CAG-cre/Esr1*)5Amc/? Tg(MMTV-Erbb2)NK1Mul/?
Background: involves: 129S2/SvPas * C57BL/6 * CBA * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(MMTV-rtTA)1Lach/? Tg(tetO-ERBB2)#Jjz/?
Background: involves: FVB/N
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Slc6a14/Slc6a14 Tg(MMTVneu)202Mul/?
Background: involves: FVB/N
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Nmi/Nmi Tg(KRT14-cre)1Amc/? Tg(MMTVneu)202Mul/?
Background: involves: 129S/SvEv * C57BL/6 * CBA * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Protein Coding Gene
MGI:1346867 | Map2k2
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:95805 | Grb2
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:97847 | Raf1
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
16168116 | J:101435
First Author: Kim A
Year: 2005
Journal: Breast Cancer Res
Title: Functional interaction between mouse erbB3 and wild-type rat c-neu in transgenic mouse mammary tumor cells.
Volume: 7
Issue: 5
Pages: R708-18
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Publication
32531343 | J:292709
 
First Author: Mitchell R
Year: 2020
Journal: Neurobiol Dis
Title: ErbB1-dependent signalling and vesicular trafficking in primary afferent nociceptors associated with hypersensitivity in neuropathic pain.
Volume: 142
Pages: 104961
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Publication
8135813 | J:17186
First Author: Fujita Y
Year: 1994
Journal: Biochem Biophys Res Commun
Title: A novel heparin-binding protein, HBp15, is identified as mammalian ribosomal protein L22.
Volume: 199
Issue: 2
Pages: 706-13
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Publication
26637193 | J:259642
First Author: Sasaki K
Year: 2015
Journal: Mol Brain
Title: NMDA receptor agonists reverse impaired psychomotor and cognitive functions associated with hippocampal Hbegf-deficiency in mice.
Volume: 8
Issue: 1
Pages: 83
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Protein
Q60631-1
 
Organism: Mus musculus/domesticus
Length:  
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Publication
22457761 | J:187135
First Author: Khalil S
Year: 2012
Journal: PLoS One
Title: Activation status of Wnt/ß-catenin signaling in normal and neoplastic breast tissues: relationship to HER2/neu expression in human and mouse.
Volume: 7
Issue: 3
Pages: e33421
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Publication
31704972 | J:336875
First Author: Nie L
Year: 2019
Journal: Nat Commun
Title: CDK2-mediated site-specific phosphorylation of EZH2 drives and maintains triple-negative breast cancer.
Volume: 10
Issue: 1
Pages: 5114
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Publication
25908435 | J:222799
 
First Author: Pathania R
Year: 2015
Journal: Nat Commun
Title: DNMT1 is essential for mammary and cancer stem cell maintenance and tumorigenesis.
Volume: 6
Pages: 6910
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Publication
17310989 | J:125541
First Author: Ke Y
Year: 2007
Journal: Oncogene
Title: Role of Gab2 in mammary tumorigenesis and metastasis.
Volume: 26
Issue: 34
Pages: 4951-60
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Publication
32931746 | J:297182
First Author: Chen X
Year: 2020
Journal: Mol Cell
Title: Cell-Autonomous versus Systemic Akt Isoform Deletions Uncovered New Roles for Akt1 and Akt2 in Breast Cancer.
Volume: 80
Issue: 1
Pages: 87-101.e5
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Publication
19847259 | J:153747
First Author: Trimboli AJ
Year: 2009
Journal: Nature
Title: Pten in stromal fibroblasts suppresses mammary epithelial tumours.
Volume: 461
Issue: 7267
Pages: 1084-91
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Publication
31167148 | J:278980
First Author: Cianciaruso C
Year: 2019
Journal: Cell Rep
Title: Molecular Profiling and Functional Analysis of Macrophage-Derived Tumor Extracellular Vesicles.
Volume: 27
Issue: 10
Pages: 3062-3080.e11
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Publication
21715565 | J:175447
First Author: González-Martín A
Year: 2011
Journal: Cancer Res
Title: Maximal T cell-mediated antitumor responses rely upon CCR5 expression in both CD4(+) and CD8(+) T cells.
Volume: 71
Issue: 16
Pages: 5455-66
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Publication
24332913 | J:205494
First Author: Cheung KJ
Year: 2013
Journal: Cell
Title: Collective invasion in breast cancer requires a conserved basal epithelial program.
Volume: 155
Issue: 7
Pages: 1639-51
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Publication
37579145 | J:345289
First Author: Dibra D
Year: 2023
Journal: Proc Natl Acad Sci U S A
Title: Triple-negative breast tumors are dependent on mutant p53 for growth and survival.
Volume: 120
Issue: 34
Pages: e2308807120
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Publication
18242514 | J:131913
First Author: Kouros-Mehr H
Year: 2008
Journal: Cancer Cell
Title: GATA-3 links tumor differentiation and dissemination in a luminal breast cancer model.
Volume: 13
Issue: 2
Pages: 141-52
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Publication
21325354 | J:170476
First Author: Bosch-Marcé M
Year: 2011
Journal: Hum Mol Genet
Title: Increased IGF-1 in muscle modulates the phenotype of severe SMA mice.
Volume: 20
Issue: 9
Pages: 1844-53
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Publication
17210696 | J:117336
First Author: Maroulakou IG
Year: 2007
Journal: Cancer Res
Title: Akt1 ablation inhibits, whereas Akt2 ablation accelerates, the development of mammary adenocarcinomas in mouse mammary tumor virus (MMTV)-ErbB2/neu and MMTV-polyoma middle T transgenic mice.
Volume: 67
Issue: 1
Pages: 167-77
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Publication
12498714 | J:81083
First Author: Moody SE
Year: 2002
Journal: Cancer Cell
Title: Conditional activation of Neu in the mammary epithelium of transgenic mice results in reversible pulmonary metastasis.
Volume: 2
Issue: 6
Pages: 451-61
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Publication
27292643 | J:238300
First Author: Rowald K
Year: 2016
Journal: Cell Rep
Title: Negative Selection and Chromosome Instability Induced by Mad2 Overexpression Delay Breast Cancer but Facilitate Oncogene-Independent Outgrowth.
Volume: 15
Issue: 12
Pages: 2679-91
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Publication
20388783 | J:159368
First Author: Menon R
Year: 2010
Journal: Cancer Res
Title: Proteomic characterization of novel alternative splice variant proteins in human epidermal growth factor receptor 2/neu-induced breast cancers.
Volume: 70
Issue: 9
Pages: 3440-9
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Publication
16169465 | J:102242
First Author: Moody SE
Year: 2005
Journal: Cancer Cell
Title: The transcriptional repressor Snail promotes mammary tumor recurrence.
Volume: 8
Issue: 3
Pages: 197-209
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Publication
23770012 | J:199068
First Author: Alvarez JV
Year: 2013
Journal: Cancer Cell
Title: Par-4 downregulation promotes breast cancer recurrence by preventing multinucleation following targeted therapy.
Volume: 24
Issue: 1
Pages: 30-44
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Publication
21653680 | J:174220
First Author: Pitteri SJ
Year: 2011
Journal: Cancer Res
Title: Tumor microenvironment-derived proteins dominate the plasma proteome response during breast cancer induction and progression.
Volume: 71
Issue: 15
Pages: 5090-100
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Publication
32690136 | J:293910
   
First Author: Alladin A
Year: 2020
Journal: Elife
Title: Tracking cells in epithelial acini by light sheet microscopy reveals proximity effects in breast cancer initiation.
Volume: 9
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Publication
33147463 | J:306551
First Author: Mabe NW
Year: 2020
Journal: Cell Rep
Title: G9a Promotes Breast Cancer Recurrence through Repression of a Pro-inflammatory Program.
Volume: 33
Issue: 5
Pages: 108341
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Publication
24786206 | J:217848
First Author: Feng Y
Year: 2014
Journal: Cancer Discov
Title: SPSB1 promotes breast cancer recurrence by potentiating c-MET signaling.
Volume: 4
Issue: 7
Pages: 790-803
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Publication
31116976 | J:288501
First Author: Kenny TC
Year: 2019
Journal: Cell Rep
Title: Mitohormesis Primes Tumor Invasion and Metastasis.
Volume: 27
Issue: 8
Pages: 2292-2303.e6
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Publication
28377454 | J:242298
First Author: Domingues PH
Year: 2017
Journal: Cancer Res
Title: Cellular Prion Protein PrPC and Ecto-5'-Nucleotidase Are Markers of the Cellular Stress Response to Aneuploidy.
Volume: 77
Issue: 11
Pages: 2914-2926
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Publication
25239452 | J:216979
First Author: Alvarez JV
Year: 2014
Journal: Cancer Res
Title: Oncogene pathway activation in mammary tumors dictates FDG-PET uptake.
Volume: 74
Issue: 24
Pages: 7583-98
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Publication
25164007 | J:216698
First Author: Payne AW
Year: 2014
Journal: Cancer Res
Title: Ceramide kinase promotes tumor cell survival and mammary tumor recurrence.
Volume: 74
Issue: 21
Pages: 6352-63
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Publication
37452072 | J:338383
First Author: Pan F
Year: 2023
Journal: Cell Death Dis
Title: FOXM1 is critical for the fitness recovery of chromosomally unstable cells.
Volume: 14
Issue: 7
Pages: 430
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Publication
16413468 | J:105045
First Author: Landis MW
Year: 2006
Journal: Cancer Cell
Title: Cyclin D1-dependent kinase activity in murine development and mammary tumorigenesis.
Volume: 9
Issue: 1
Pages: 13-22
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Publication
15535849 | J:94093
First Author: Mikaelian I
Year: 2004
Journal: Breast Cancer Res
Title: Proteotypic classification of spontaneous and transgenic mammary neoplasms.
Volume: 6
Issue: 6
Pages: R668-79
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Publication
35533313 | J:329874
First Author: Wu J
Year: 2022
Journal: Mol Cancer Res
Title: Stromal p53 Regulates Breast Cancer Development, the Immune Landscape, and Survival in an Oncogene-Specific Manner.
Volume: 20
Issue: 8
Pages: 1233-1246
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Publication
28396358 | J:242495
First Author: Hanker AB
Year: 2017
Journal: Cancer Res
Title: Extracellular Matrix/Integrin Signaling Promotes Resistance to Combined Inhibition of HER2 and PI3K in HER2+ Breast Cancer.
Volume: 77
Issue: 12
Pages: 3280-3292
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Publication
22037875 | J:178842
First Author: Zhang Q
Year: 2011
Journal: Cancer Res
Title: Cyclin D3 compensates for the loss of cyclin D1 during ErbB2-induced mammary tumor initiation and progression.
Volume: 71
Issue: 24
Pages: 7513-24
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Publication
29326438 | J:261035
First Author: Pruitt HC
Year: 2018
Journal: Oncogene
Title: Conditional knockout of N-Myc and STAT interactor disrupts normal mammary development and enhances metastatic ability of mammary tumors.
Volume: 37
Issue: 12
Pages: 1610-1623
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Publication
18079437 | J:130531
First Author: Koyama H
Year: 2008
Journal: Am J Pathol
Title: Significance of tumor-associated stroma in promotion of intratumoral lymphangiogenesis: pivotal role of a hyaluronan-rich tumor microenvironment.
Volume: 172
Issue: 1
Pages: 179-93
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Publication
29610308 | J:261482
First Author: Vega-Rubín-de-Celis S
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Increased autophagy blocks HER2-mediated breast tumorigenesis.
Volume: 115
Issue: 16
Pages: 4176-4181
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Publication
21849469 | J:205401
First Author: Balavenkatraman KK
Year: 2011
Journal: Mol Cancer Res
Title: Epithelial protein-tyrosine phosphatase 1B contributes to the induction of mammary tumors by HER2/Neu but is not essential for tumor maintenance.
Volume: 9
Issue: 10
Pages: 1377-84
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Publication
26331542 | J:225955
First Author: Ye X
Year: 2015
Journal: Nature
Title: Distinct EMT programs control normal mammary stem cells and tumour-initiating cells.
Volume: 525
Issue: 7568
Pages: 256-60
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Genotype
Genotype
Symbol: Tg(MMTV-rtTA)1Lach/? Tg(TetO-Erbb2)1Lach/?
Background: involves: FVB
Zygosity: cx
Has Mutant Allele: true
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Protein Coding Gene
MGI:88068 | Areg
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
10601328 | J:113867
First Author: Blanco-Aparicio C
Year: 1999
Journal: J Cell Biol
Title: A novel regulatory mechanism of MAP kinases activation and nuclear translocation mediated by PKA and the PTP-SL tyrosine phosphatase.
Volume: 147
Issue: 6
Pages: 1129-36
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Publication
35102343 | J:326915
First Author: Zhou L
Year: 2022
Journal: Nat Immunol
Title: Group 3 innate lymphoid cells produce the growth factor HB-EGF to protect the intestine from TNF-mediated inflammation.
Volume: 23
Issue: 2
Pages: 251-261
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Publication
31127030 | J:276944
First Author: Farahnak S
Year: 2019
Journal: J Immunol
Title: HB-EGF Synthesized by CD4 T Cells Modulates Allergic Airway Eosinophilia by Regulating IL-5 Synthesis.
Volume: 203
Issue: 1
Pages: 39-47
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Publication
17986609 | J:127448
First Author: Xie H
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Maternal heparin-binding-EGF deficiency limits pregnancy success in mice.
Volume: 104
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