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  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
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Search results 2201 to 2300 out of 2412 for Comp

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0.017s

Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Protein
Q91YP4
Organism: Mus musculus/domesticus
Length: 235  
Fragment?: false
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Protein
A0A087WRI0
Organism: Mus musculus/domesticus
Length: 179  
Fragment?: true
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Protein
Q8C9R1
Organism: Mus musculus/domesticus
Length: 310  
Fragment?: false
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Protein
Q8BVQ2
Organism: Mus musculus/domesticus
Length: 335  
Fragment?: false
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Protein
Q19NU2
Organism: Mus musculus/domesticus
Length: 66  
Fragment?: true
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Protein
Q3UQW9
Organism: Mus musculus/domesticus
Length: 484  
Fragment?: true
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Protein
A0A087WSA1
Organism: Mus musculus/domesticus
Length: 398  
Fragment?: false
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Protein
Q6A040
Organism: Mus musculus/domesticus
Length: 402  
Fragment?: true
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Protein
Q3TEM5
Organism: Mus musculus/domesticus
Length: 129  
Fragment?: true
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Protein
Q69ZM2
Organism: Mus musculus/domesticus
Length: 276  
Fragment?: true
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Protein
E9PWD2
Organism: Mus musculus/domesticus
Length: 1646  
Fragment?: false
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Protein
D3Z366
Organism: Mus musculus/domesticus
Length: 379  
Fragment?: true
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Protein
D3Z044
Organism: Mus musculus/domesticus
Length: 134  
Fragment?: true
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Protein
Q1W767
Organism: Mus musculus/domesticus
Length: 66  
Fragment?: true
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Protein
Q3UV61
Organism: Mus musculus/domesticus
Length: 423  
Fragment?: true
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Protein
Q14BI4
Organism: Mus musculus/domesticus
Length: 328  
Fragment?: false
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Protein
Q9D201
Organism: Mus musculus/domesticus
Length: 130  
Fragment?: false
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Protein
E9QNR5
Organism: Mus musculus/domesticus
Length: 1646  
Fragment?: false
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Protein
D3Z0T6
Organism: Mus musculus/domesticus
Length: 70  
Fragment?: true
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Protein
A2AE15
Organism: Mus musculus/domesticus
Length: 464  
Fragment?: false
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Protein
Q8BHP3
Organism: Mus musculus/domesticus
Length: 1107  
Fragment?: false
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Publication
2459396 | -
First Author: Patthy L
Year: 1988
Journal: J Mol Biol
Title: Detecting distant homologies of mosaic proteins. Analysis of the sequences of thrombomodulin, thrombospondin complement components C9, C8 alpha and C8 beta, vitronectin and plasma cell membrane glycoprotein PC-1.
Volume: 202
Issue: 4
Pages: 689-96
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Publication
10508153 | -
First Author: Wengelnik K
Year: 1999
Journal: EMBO J
Title: The A-domain and the thrombospondin-related motif of Plasmodium falciparum TRAP are implicated in the invasion process of mosquito salivary glands.
Volume: 18
Issue: 19
Pages: 5195-204
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Publication
1501644 | -
First Author: Rogers WO
Year: 1992
Journal: Mol Biochem Parasitol
Title: Characterization of the gene encoding sporozoite surface protein 2, a protective Plasmodium yoelii sporozoite antigen.
Volume: 53
Issue: 1-2
Pages: 45-51
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Publication
1417780 | -
 
First Author: Nolan KF
Year: 1992
Journal: Biochem J
Title: Characterization of the human properdin gene.
Volume: 287 ( Pt 1)
Pages: 291-7
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Publication
1868073 | -
First Author: Smith KF
Year: 1991
Journal: Biochemistry
Title: Neutron and X-ray scattering studies on the human complement protein properdin provide an analysis of the thrombospondin repeat.
Volume: 30
Issue: 32
Pages: 8000-8
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Publication
9135017 | -
First Author: Guo N
Year: 1997
Journal: Cancer Res
Title: Thrombospondin 1 and type I repeat peptides of thrombospondin 1 specifically induce apoptosis of endothelial cells.
Volume: 57
Issue: 9
Pages: 1735-42
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Publication
10500044 | J:103236
First Author: Iruela-Arispe ML
Year: 1999
Journal: Circulation
Title: Inhibition of angiogenesis by thrombospondin-1 is mediated by 2 independent regions within the type 1 repeats.
Volume: 100
Issue: 13
Pages: 1423-31
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Publication
15014436 | -
First Author: Kvansakul M
Year: 2004
Journal: EMBO J
Title: Structure of a thrombospondin C-terminal fragment reveals a novel calcium core in the type 3 repeats.
Volume: 23
Issue: 6
Pages: 1223-33
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Protein
A0A1D5RM48
Organism: Mus musculus/domesticus
Length: 81  
Fragment?: true
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Protein
Q3V489
Organism: Mus musculus/domesticus
Length: 234  
Fragment?: false
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Protein
A0A1L1STL9
Organism: Mus musculus/domesticus
Length: 112  
Fragment?: false
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Protein Domain
IPR036383 | TSP1_rpt_sf
Type: Homologous_superfamily
Description: Thrombospondins are multimeric multidomain glycoproteins that function at cell surfaces and in the extracellular matrix milieu. They act as regulators of cell interactions in vertebrates. They are divided into two subfamilies, A and B, according to their overall molecular organisation. The subgroup A proteins TSP-1 and -2 contain an N-terminal domain, a VWFC domain, three TSP1 repeats, three EGF-like domains, TSP3 repeats and a C-terminal domain.They are assembled as trimer. The subgroup B thrombospondins, designated TSP-3, -4, and COMP (cartilage oligomeric matrix protein, also designated TSP-5) are distinct in that they contain unique N-terminal regions, lack the VWFC domain and TSP1 repeats, contain four copies of EGF-like domains, and are assembled as pentamers []. EGF, TSP3 repeats and the C-terminal domain are thus the hallmark of a thrombospondin.This repeat was first described in 1986 by Lawler and Hynes []. It was found in the thrombospondin protein where it is repeated 3 times. Now a number of proteins involved in the complement pathway (properdin, C6, C7, C8A, C8B, C9) []as well as extracellular matrix protein like mindin, F-spondin [], SCO-spondin and even the circumsporozoite surface protein 2 and TRAP proteins of Plasmodium [, ]contain one or more instance of this repeat. It has been involved in cell-cell interaction, inhibition of angiogenesis []and apoptosis [].The intron-exon organisation of the properdin gene confirms the hypothesis that the repeat might have evolved by a process involving exon shuffling []. A study of properdin structure provides some information about the structure of the thrombospondin type I repeat [].The TSP1 repeat structure has a disulfide-rich fold with all-beta sheets, each with three antiparallel strands.
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Protein
Q8K2B7
Organism: Mus musculus/domesticus
Length: 563  
Fragment?: true
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Protein
F6W6J3
Organism: Mus musculus/domesticus
Length: 104  
Fragment?: true
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Protein
D3Z6N1
Organism: Mus musculus/domesticus
Length: 131  
Fragment?: true
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Protein
A2ATD1
Organism: Mus musculus/domesticus
Length: 454  
Fragment?: false
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Protein
Q3UPR9
Organism: Mus musculus/domesticus
Length: 264  
Fragment?: false
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Protein
Q8BMS2
Organism: Mus musculus/domesticus
Length: 330  
Fragment?: false
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Protein
Q8CG66
Organism: Mus musculus/domesticus
Length: 446  
Fragment?: true
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Protein
Q6KAS6
Organism: Mus musculus/domesticus
Length: 289  
Fragment?: true
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Protein
Q3TPD3
Organism: Mus musculus/domesticus
Length: 259  
Fragment?: true
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Protein
Q1LZL1
Organism: Mus musculus/domesticus
Length: 269  
Fragment?: true
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Protein
Q8CDB8
Organism: Mus musculus/domesticus
Length: 701  
Fragment?: false
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Protein
V9GXR4
Organism: Mus musculus/domesticus
Length: 461  
Fragment?: false
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Protein
Q3TR71
Organism: Mus musculus/domesticus
Length: 416  
Fragment?: true
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Protein
A0A087WNT4
Organism: Mus musculus/domesticus
Length: 933  
Fragment?: true
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Protein
Q8VD28
Organism: Mus musculus/domesticus
Length: 330  
Fragment?: false
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Protein
Q3TP59
Organism: Mus musculus/domesticus
Length: 262  
Fragment?: true
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Protein
D3Z6A3
Organism: Mus musculus/domesticus
Length: 493  
Fragment?: false
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Protein
F6WY46
Organism: Mus musculus/domesticus
Length: 243  
Fragment?: true
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Protein
F6YQQ5
Organism: Mus musculus/domesticus
Length: 449  
Fragment?: false
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Protein
B2RTG1
Organism: Mus musculus/domesticus
Length: 658  
Fragment?: false
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Publication
2430973 | -
First Author: Lawler J
Year: 1986
Journal: J Cell Biol
Title: The structure of human thrombospondin, an adhesive glycoprotein with multiple calcium-binding sites and homologies with several different proteins.
Volume: 103
Issue: 5
Pages: 1635-48
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Publication
10409509 | J:54733
First Author: Feinstein Y
Year: 1999
Journal: Development
Title: F-spondin and mindin: two structurally and functionally related genes expressed in the hippocampus that promote outgrowth of embryonic hippocampal neurons.
Volume: 126
Issue: 16
Pages: 3637-48
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Protein
Q03350
Organism: Mus musculus/domesticus
Length: 1172  
Fragment?: false
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Protein
Q7TMT3
Organism: Mus musculus/domesticus
Length: 1172  
Fragment?: false
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Protein
Q05895
Organism: Mus musculus/domesticus
Length: 956  
Fragment?: false
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Protein
Q8VI54
Organism: Mus musculus/domesticus
Length: 755  
Fragment?: false
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Protein
A1A557
Organism: Mus musculus/domesticus
Length: 755  
Fragment?: false
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Protein
E9PWF0
Organism: Mus musculus/domesticus
Length: 919  
Fragment?: false
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Protein
P35441
Organism: Mus musculus/domesticus
Length: 1170  
Fragment?: false
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Protein
Q80YQ1
Organism: Mus musculus/domesticus
Length: 1171  
Fragment?: false
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Protein
Q8CGB2
Organism: Mus musculus/domesticus
Length: 1171  
Fragment?: false
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Protein
Q3TR40
Organism: Mus musculus/domesticus
Length: 1170  
Fragment?: false
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Protein
Q80T21
Organism: Mus musculus/domesticus
Length: 1036  
Fragment?: false
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Protein
Q8VCC9
Organism: Mus musculus/domesticus
Length: 807  
Fragment?: false
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Protein
Q9Z132
Organism: Mus musculus/domesticus
Length: 265  
Fragment?: false
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Protein
Q8BFU0
Organism: Mus musculus/domesticus
Length: 243  
Fragment?: false
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Protein
Q2TJ95
Organism: Mus musculus/domesticus
Length: 277  
Fragment?: false
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Protein
Q3UTY6
Organism: Mus musculus/domesticus
Length: 1018  
Fragment?: false
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Protein
B1ASC1
Organism: Mus musculus/domesticus
Length: 265  
Fragment?: false
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Protein
Q9CX59
Organism: Mus musculus/domesticus
Length: 192  
Fragment?: false
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Protein
A9Z1Z6
Organism: Mus musculus/domesticus
Length: 203  
Fragment?: false
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Protein
Q99JP1
Organism: Mus musculus/domesticus
Length: 183  
Fragment?: true
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Protein
Q69ZZ7
Organism: Mus musculus/domesticus
Length: 729  
Fragment?: true
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Protein
D6RGS8
Organism: Mus musculus/domesticus
Length: 684  
Fragment?: false
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Protein
A0A1L1SR88
Organism: Mus musculus/domesticus
Length: 186  
Fragment?: true
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Protein
Q9CRC7
Organism: Mus musculus/domesticus
Length: 244  
Fragment?: false
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Protein
Q7TSK7
Organism: Mus musculus/domesticus
Length: 957  
Fragment?: false
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Protein
Q62217
Organism: Mus musculus/domesticus
Length: 1077  
Fragment?: false
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Protein
Q66K08
Organism: Mus musculus/domesticus
Length: 1184  
Fragment?: false
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Protein
D3Z7H8
Organism: Mus musculus/domesticus
Length: 1162  
Fragment?: false
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Protein
Q60519
Organism: Mus musculus/domesticus
Length: 1093  
Fragment?: false
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Protein
Q9Z1T2
Organism: Mus musculus/domesticus
Length: 963  
Fragment?: false
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Protein
A0A0R4J0F8
Organism: Mus musculus/domesticus
Length: 1250  
Fragment?: false
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Protein
Q8BXU8
Organism: Mus musculus/domesticus
Length: 844  
Fragment?: false
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Protein
E9PYV8
Organism: Mus musculus/domesticus
Length: 1350  
Fragment?: false
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Protein
B2RTL6
Organism: Mus musculus/domesticus
Length: 963  
Fragment?: false
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Protein
Q3TZP8
Organism: Mus musculus/domesticus
Length: 710  
Fragment?: false
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Protein
Q6ZQ96
Organism: Mus musculus/domesticus
Length: 612  
Fragment?: true
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Protein
B7ZCH8
Organism: Mus musculus/domesticus
Length: 525  
Fragment?: false
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Protein
A1A5B7
Organism: Mus musculus/domesticus
Length: 957  
Fragment?: false
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Protein
Q3UPZ0
Organism: Mus musculus/domesticus
Length: 1074  
Fragment?: false
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Protein
Q8BJ73
Organism: Mus musculus/domesticus
Length: 228  
Fragment?: false
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Protein
A0AUN1
Organism: Mus musculus/domesticus
Length: 221  
Fragment?: true
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Protein
Q0P5Y9
Organism: Mus musculus/domesticus
Length: 228  
Fragment?: false
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Protein
P29268
Organism: Mus musculus/domesticus
Length: 348  
Fragment?: false
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Protein
Q4VC17
Organism: Mus musculus/domesticus
Length: 1219  
Fragment?: false
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Protein
Q9R001
Organism: Mus musculus/domesticus
Length: 930  
Fragment?: false
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom