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Search results 2301 to 2400 out of 2532 for Arnt

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Type Details Score
Publication
First Author: Nakashima A
Year: 2008
Journal: Mol Cell Biol
Title: DEC1 modulates the circadian phase of clock gene expression.
Volume: 28
Issue: 12
Pages: 4080-92
Publication
First Author: Lu Y
Year: 2017
Journal: Oncotarget
Title: Cancer/testis antigen PIWIL2 suppresses circadian rhythms by regulating the stability and activity of BMAL1 and CLOCK.
Volume: 8
Issue: 33
Pages: 54913-54924
Publication
First Author: Bellet MM
Year: 2012
Journal: Cell Cycle
Title: The RelB subunit of NFκB acts as a negative regulator of circadian gene expression.
Volume: 11
Issue: 17
Pages: 3304-11
Publication
First Author: Li MD
Year: 2013
Journal: Cell Metab
Title: O-GlcNAc signaling entrains the circadian clock by inhibiting BMAL1/CLOCK ubiquitination.
Volume: 17
Issue: 2
Pages: 303-10
Publication
First Author: Hou TY
Year: 2009
Journal: J Biol Chem
Title: ID2 (inhibitor of DNA binding 2) is a rhythmically expressed transcriptional repressor required for circadian clock output in mouse liver.
Volume: 284
Issue: 46
Pages: 31735-45
Publication
First Author: Ward SM
Year: 2010
Journal: J Biol Chem
Title: The transcriptional repressor ID2 can interact with the canonical clock components CLOCK and BMAL1 and mediate inhibitory effects on mPer1 expression.
Volume: 285
Issue: 50
Pages: 38987-9000
Publication
First Author: Lee J
Year: 2008
Journal: Mol Cell Biol
Title: Dual modification of BMAL1 by SUMO2/3 and ubiquitin promotes circadian activation of the CLOCK/BMAL1 complex.
Volume: 28
Issue: 19
Pages: 6056-65
Publication
First Author: Lande-Diner L
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: A positive feedback loop links circadian clock factor CLOCK-BMAL1 to the basic transcriptional machinery.
Volume: 110
Issue: 40
Pages: 16021-6
Publication
First Author: Tremblay F
Year: 2012
Journal: Endocrinology
Title: Loss of coiled-coil domain containing 80 negatively modulates glucose homeostasis in diet-induced obese mice.
Volume: 153
Issue: 9
Pages: 4290-303
Publication
First Author: Chappell PE
Year: 2003
Journal: J Neurosci
Title: Circadian gene expression regulates pulsatile gonadotropin-releasing hormone (GnRH) secretory patterns in the hypothalamic GnRH-secreting GT1-7 cell line.
Volume: 23
Issue: 35
Pages: 11202-13
Publication
First Author: Seok SH
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Structural hierarchy controlling dimerization and target DNA recognition in the AHR transcriptional complex.
Volume: 114
Issue: 21
Pages: 5431-5436
Publication
First Author: DiTacchio L
Year: 2011
Journal: Science
Title: Histone lysine demethylase JARID1a activates CLOCK-BMAL1 and influences the circadian clock.
Volume: 333
Issue: 6051
Pages: 1881-5
Publication
First Author: Devos J
Year: 2011
Journal: J Circadian Rhythms
Title: Magel2, a Prader-Willi syndrome candidate gene, modulates the activities of circadian rhythm proteins in cultured cells.
Volume: 9
Issue: 1
Pages: 12
Publication
First Author: Yoshitane H
Year: 2012
Journal: EMBO Rep
Title: JNK regulates the photic response of the mammalian circadian clock.
Volume: 13
Issue: 5
Pages: 455-61
Publication
First Author: Asher G
Year: 2008
Journal: Cell
Title: SIRT1 regulates circadian clock gene expression through PER2 deacetylation.
Volume: 134
Issue: 2
Pages: 317-28
Publication  
First Author: Langmesser S
Year: 2008
Journal: BMC Mol Biol
Title: Interaction of circadian clock proteins PER2 and CRY with BMAL1 and CLOCK.
Volume: 9
Pages: 41
Publication  
First Author: Li DQ
Year: 2013
Journal: Nat Commun
Title: Metastasis-associated protein 1 is an integral component of the circadian molecular machinery.
Volume: 4
Pages: 2545
Publication
First Author: Luo Q
Year: 2019
Journal: Invest Ophthalmol Vis Sci
Title: The Diurnal Rhythm of Insulin Receptor Substrate-1 (IRS-1) and Kir4.1 in Diabetes: Implications for a Clock Gene Bmal1.
Volume: 60
Issue: 6
Pages: 1928-1936
Publication
First Author: Zwighaft Z
Year: 2015
Journal: Cell Metab
Title: Circadian Clock Control by Polyamine Levels through a Mechanism that Declines with Age.
Volume: 22
Issue: 5
Pages: 874-85
Publication
First Author: Janssen H
Year: 2023
Journal: Immunity
Title: Monocytes re-enter the bone marrow during fasting and alter the host response to infection.
Volume: 56
Issue: 4
Pages: 783-796.e7
Publication
First Author: Godinho-Silva C
Year: 2019
Journal: Nature
Title: Light-entrained and brain-tuned circadian circuits regulate ILC3s and gut homeostasis.
Volume: 574
Issue: 7777
Pages: 254-258
Publication
First Author: Liu AC
Year: 2008
Journal: PLoS Genet
Title: Redundant function of REV-ERBalpha and beta and non-essential role for Bmal1 cycling in transcriptional regulation of intracellular circadian rhythms.
Volume: 4
Issue: 2
Pages: e1000023
Publication
First Author: Sasaki M
Year: 2009
Journal: J Biol Chem
Title: Preferential inhibition of BMAL2-CLOCK activity by PER2 reemphasizes its negative role and a positive role of BMAL2 in the circadian transcription.
Volume: 284
Issue: 37
Pages: 25149-59
Publication
First Author: Honma S
Year: 2002
Journal: Nature
Title: Dec1 and Dec2 are regulators of the mammalian molecular clock.
Volume: 419
Issue: 6909
Pages: 841-4
Publication
First Author: Xiao J
Year: 2013
Journal: J Biol Chem
Title: Transcription factor NF-Y is a functional regulator of the transcription of core clock gene Bmal1.
Volume: 288
Issue: 44
Pages: 31930-6
Publication
First Author: Bertolucci C
Year: 2008
Journal: Mol Cell Biol
Title: Evidence for an overlapping role of CLOCK and NPAS2 transcription factors in liver circadian oscillators.
Volume: 28
Issue: 9
Pages: 3070-5
Publication
First Author: Hamaguchi H
Year: 2004
Journal: Biochem J
Title: Expression of the gene for Dec2, a basic helix-loop-helix transcription factor, is regulated by a molecular clock system.
Volume: 382
Issue: Pt 1
Pages: 43-50
Strain
Attribute String: mutant strain, targeted mutation, transgenic, congenic
Genotype
Symbol: Bmal1/Bmal1 Tg(Scg2-tTA)1Jt/? Tg(tetO-Arntl)1Jt/?
Background: involves: 129/Sv * C57BL/6J * CD-1
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Bmal1/Bmal1 Syt10/Syt10
Background: involves: 129S2/SvPas * 129S4/SvJaeSor * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Bmal1/Bmal1 Pgr/Pgr<+>
Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Bmal1/Bmal1 Pgr/Pgr<+>
Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Bmal1/Bmal1 Speer6-ps1/?
Background: B6.Cg-Bmal1 Speer6-ps1
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Bmal1/Bmal1 Myl1/Myl1<+>
Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Bmal1/Bmal1 Speer6-ps1/?
Background: involves: 129S4/SvJae * C57BL/6 * DBA
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Bmal1/Bmal1 Nfil3/Nfil3 Tg(Myh6-cre)2182Mds/?
Background: involves: 129 * C57BL/6 * FVB/N
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Bmal1/Bmal1 Scgb1a1/Scgb1a1<+>
Background: involves: 129 * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Bmal1/Bmal1 Lyz2/Lyz2<+>
Background: involves: 129 * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Bmal1/Bmal1 Per2/Per2 Tg(Col2a1-cre)1Asz/?
Background: involves: 129 * C57BL/6J * CBA
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Bmal1/Bmal1 Krt14/Krt14<+>
Background: involves: 129S2/SvPas * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Bmal1/Bmal1 Syt10/Syt10<+> Tg(ACTA1-cre)79Jme/?
Background: involves: 129S2/SvPas * C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: Koyanagi S
Year: 2011
Journal: J Biol Chem
Title: cAMP-response element (CRE)-mediated transcription by activating transcription factor-4 (ATF4) is essential for circadian expression of the Period2 gene.
Volume: 286
Issue: 37
Pages: 32416-23
Publication
First Author: Chen R
Year: 2009
Journal: Mol Cell
Title: Rhythmic PER abundance defines a critical nodal point for negative feedback within the circadian clock mechanism.
Volume: 36
Issue: 3
Pages: 417-30
Publication
First Author: Ramsey KM
Year: 2009
Journal: Science
Title: Circadian clock feedback cycle through NAMPT-mediated NAD+ biosynthesis.
Volume: 324
Issue: 5927
Pages: 651-4
Publication
First Author: Shi G
Year: 2016
Journal: Cell Rep
Title: Distinct Roles of HDAC3 in the Core Circadian Negative Feedback Loop Are Critical for Clock Function.
Volume: 14
Issue: 4
Pages: 823-834
Publication
First Author: Kojima S
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: LARK activates posttranscriptional expression of an essential mammalian clock protein, PERIOD1.
Volume: 104
Issue: 6
Pages: 1859-64
Publication
First Author: Katada S
Year: 2010
Journal: Nat Struct Mol Biol
Title: The histone methyltransferase MLL1 permits the oscillation of circadian gene expression.
Volume: 17
Issue: 12
Pages: 1414-21
Publication
First Author: Naruse Y
Year: 2004
Journal: Mol Cell Biol
Title: Circadian and light-induced transcription of clock gene Per1 depends on histone acetylation and deacetylation.
Volume: 24
Issue: 14
Pages: 6278-87
Publication
First Author: Yang Y
Year: 2012
Journal: Biol Open
Title: Regulation of behavioral circadian rhythms and clock protein PER1 by the deubiquitinating enzyme USP2.
Volume: 1
Issue: 8
Pages: 789-801
Publication
First Author: Annayev Y
Year: 2014
Journal: J Biol Chem
Title: Gene model 129 (Gm129) encodes a novel transcriptional repressor that modulates circadian gene expression.
Volume: 289
Issue: 8
Pages: 5013-24
Publication
First Author: Dudley CA
Year: 2003
Journal: Science
Title: Altered patterns of sleep and behavioral adaptability in NPAS2-deficient mice.
Volume: 301
Issue: 5631
Pages: 379-83
Publication
First Author: Kondratov RV
Year: 2003
Journal: Genes Dev
Title: BMAL1-dependent circadian oscillation of nuclear CLOCK: posttranslational events induced by dimerization of transcriptional activators of the mammalian clock system.
Volume: 17
Issue: 15
Pages: 1921-32
Publication
First Author: Zhang W
Year: 2016
Journal: FASEB J
Title: Rhythmic expression of miR-27b-3p targets the clock gene Bmal1 at the posttranscriptional level in the mouse liver.
Volume: 30
Issue: 6
Pages: 2151-60
Publication
First Author: Asher G
Year: 2010
Journal: Cell
Title: Poly(ADP-ribose) polymerase 1 participates in the phase entrainment of circadian clocks to feeding.
Volume: 142
Issue: 6
Pages: 943-53
Publication
First Author: Jin X
Year: 1999
Journal: Cell
Title: A molecular mechanism regulating rhythmic output from the suprachiasmatic circadian clock.
Volume: 96
Issue: 1
Pages: 57-68
Publication
First Author: Shearman LP
Year: 2000
Journal: Science
Title: Interacting molecular loops in the mammalian circadian clock.
Volume: 288
Issue: 5468
Pages: 1013-9
Publication
First Author: Ripperger JA
Year: 2006
Journal: Nat Genet
Title: Rhythmic CLOCK-BMAL1 binding to multiple E-box motifs drives circadian Dbp transcription and chromatin transitions.
Volume: 38
Issue: 3
Pages: 369-74
Publication  
First Author: Weger BD
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: Systematic analysis of differential rhythmic liver gene expression mediated by the circadian clock and feeding rhythms.
Volume: 118
Issue: 3
Publication
First Author: Militi S
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Early doors (Edo) mutant mouse reveals the importance of period 2 (PER2) PAS domain structure for circadian pacemaking.
Volume: 113
Issue: 10
Pages: 2756-61
Publication
First Author: Dunlap JC
Year: 1999
Journal: Cell
Title: Molecular bases for circadian clocks.
Volume: 96
Issue: 2
Pages: 271-90
Publication
First Author: Tamayo AG
Year: 2015
Journal: Nat Struct Mol Biol
Title: Histone monoubiquitination by Clock-Bmal1 complex marks Per1 and Per2 genes for circadian feedback.
Volume: 22
Issue: 10
Pages: 759-66
Publication
First Author: Tamaru T
Year: 2015
Journal: PLoS Biol
Title: CRY Drives Cyclic CK2-Mediated BMAL1 Phosphorylation to Control the Mammalian Circadian Clock.
Volume: 13
Issue: 11
Pages: e1002293
Publication
First Author: Hogenesch JB
Year: 1998
Journal: Proc Natl Acad Sci U S A
Title: The basic-helix-loop-helix-PAS orphan MOP3 forms transcriptionally active complexes with circadian and hypoxia factors.
Volume: 95
Issue: 10
Pages: 5474-9
Publication
First Author: Bebas P
Year: 2009
Journal: FASEB J
Title: Circadian clock and output genes are rhythmically expressed in extratesticular ducts and accessory organs of mice.
Volume: 23
Issue: 2
Pages: 523-33
Publication
First Author: Ansari N
Year: 2009
Journal: Eur J Neurosci
Title: Differential maturation of circadian rhythms in clock gene proteins in the suprachiasmatic nucleus and the pars tuberalis during mouse ontogeny.
Volume: 29
Issue: 3
Pages: 477-89
Publication
First Author: Lee Y
Year: 2010
Journal: J Cell Sci
Title: Coactivation of the CLOCK-BMAL1 complex by CBP mediates resetting of the circadian clock.
Volume: 123
Issue: Pt 20
Pages: 3547-57
Protein
Organism: Mus musculus/domesticus
Length: 160  
Fragment?: true
Protein Domain
Type: Family
Description: The Ah (dioxin) receptor nuclear translocator protein (Arnt) belongs to the basichelix-loop-helix (bHLH) family of transcription factors and is required forAh receptor function. The Ah receptor binds, and mediates the carcinogeniceffects of a variety of environmental pollutants, including 2,3,7,8-tetrachlorodibenzo-p-dioxin and polycyclic aromatic hydrocarbons. Arnt is a structural component of theXRE-binding form of the Ah receptor. These proteins are class VII members of the basic helix-loop-helix (bHLH) family. The bHLH domain may be responsible for interacting with both the XRE and the ligand-bindingsubunit [, ].The activated Ah receptor and Arnt protein bind DNA as a heterodimer. Bothproteins contain PAS homology regions, which in Drosophila PER and SIMproteins function as dimerisation domains [].
Publication
First Author: Ando H
Year: 2011
Journal: Endocrinology
Title: Impairment of peripheral circadian clocks precedes metabolic abnormalities in ob/ob mice.
Volume: 152
Issue: 4
Pages: 1347-54
Protein Domain
Type: Family
Description: Aryl hydrocarbon receptor (AHR) is a ligand-activated transcription factor that mediates the biological and toxic effects of dioxin-like compounds []. Upon ligand binding, the receptor translocates into the nucleus where it heterodimerises with ARNT (AHR nuclear translocator) []. The aryl hydrocarbon receptor repressor (AHRR) competes with AHR for the binding of ARNT, and thereby repressing AHR's transcription activity [].
Protein Domain
Type: Family
Description: Aryl hydrocarbon receptor (AHR) is a ligand-activated transcription factor that mediates the biological and toxic effects of dioxin-like compounds []. Upon ligand binding, the receptor translocates into the nucleus where it heterodimerises with ARNT (AHR nuclear translocator) []. The aryl hydrocarbon receptor repressor (AHRR) competes with AHR for the binding of ARNT, and thereby repressing AHR's transcription activity [].
Publication
First Author: Metz RP
Year: 2006
Journal: J Biol Chem
Title: Differential transcriptional regulation by mouse single-minded 2s.
Volume: 281
Issue: 16
Pages: 10839-48
Publication
First Author: Anafi RC
Year: 2014
Journal: PLoS Biol
Title: Machine learning helps identify CHRONO as a circadian clock component.
Volume: 12
Issue: 4
Pages: e1001840
Publication
First Author: Duffield GE
Year: 2009
Journal: Curr Biol
Title: A role for Id2 in regulating photic entrainment of the mammalian circadian system.
Volume: 19
Issue: 4
Pages: 297-304
Publication
First Author: Preitner N
Year: 2002
Journal: Cell
Title: The orphan nuclear receptor REV-ERBalpha controls circadian transcription within the positive limb of the mammalian circadian oscillator.
Volume: 110
Issue: 2
Pages: 251-60
Publication
First Author: Dolatshad H
Year: 2010
Journal: PLoS One
Title: Differential expression of the circadian clock in maternal and embryonic tissues of mice.
Volume: 5
Issue: 3
Pages: e9855
Publication
First Author: Ratajczak CK
Year: 2010
Journal: Reprod Fertil Dev
Title: Clock gene expression in gravid uterus and extra-embryonic tissues during late gestation in the mouse.
Volume: 22
Issue: 5
Pages: 743-50
Publication
First Author: Koike N
Year: 2012
Journal: Science
Title: Transcriptional architecture and chromatin landscape of the core circadian clock in mammals.
Volume: 338
Issue: 6105
Pages: 349-54
Genotype
Symbol: Bmal1/Bmal1 Syt10/Syt10<+>
Background: involves: 129S2/SvPas * 129S4/SvJaeSor * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Bmal1/Bmal1<+> Usp2/Usp2<+>
Background: involves: 129 * C57BL/6
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Bmal1/Bmal1 Speer6-ps1/Speer6-ps1<+>
Background: involves: C57BL/6 * C57BL/6J * DBA
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Bmal1/Bmal1<+> Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Avp-icre)#Meid/?
Background: involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6JSlc * C57BL/6NCrl
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Bmal1/Bmal1 Per2/Per2<+> Tg(Col6a1-cre)1Gkl/?
Background: involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6J * CBA * DBA/1
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Bmal1/Bmal1 Krt14/Krt14<+> Syt10/Syt10<+>
Background: involves: 129S2/SvPas * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Bmal1/Bmal1 Speer6-ps1/Speer6-ps1<+>
Background: involves: 129 * C57BL/6J
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: Goriki A
Year: 2014
Journal: PLoS Biol
Title: A novel protein, CHRONO, functions as a core component of the mammalian circadian clock.
Volume: 12
Issue: 4
Pages: e1001839
Publication
First Author: Lee C
Year: 2004
Journal: Mol Cell Biol
Title: Direct association between mouse PERIOD and CKIepsilon is critical for a functioning circadian clock.
Volume: 24
Issue: 2
Pages: 584-94
Publication
First Author: Etchegaray JP
Year: 2006
Journal: J Biol Chem
Title: The polycomb group protein EZH2 is required for mammalian circadian clock function.
Volume: 281
Issue: 30
Pages: 21209-15
Publication
First Author: Chavan R
Year: 2017
Journal: Biol Open
Title: REV-ERBα regulates Fgf21 expression in the liver via hepatic nuclear factor 6.
Volume: 6
Issue: 1
Pages: 1-7
Publication
First Author: Umemura Y
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Involvement of posttranscriptional regulation of Clock in the emergence of circadian clock oscillation during mouse development.
Volume: 114
Issue: 36
Pages: E7479-E7488
Publication
First Author: Xu Y
Year: 2016
Journal: PLoS Genet
Title: Long-Range Chromosome Interactions Mediated by Cohesin Shape Circadian Gene Expression.
Volume: 12
Issue: 5
Pages: e1005992
Publication
First Author: Wallach T
Year: 2013
Journal: PLoS Genet
Title: Dynamic circadian protein-protein interaction networks predict temporal organization of cellular functions.
Volume: 9
Issue: 3
Pages: e1003398
Publication
First Author: Cao X
Year: 2022
Journal: J Mol Histol
Title: Analyses of the circadian clock genes expression in whole embryos and maternal major tissues of mice.
Volume: 53
Issue: 2
Pages: 473-482
Protein
Organism: Mus musculus/domesticus
Length: 429  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 429  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 429  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 429  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 141  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 429  
Fragment?: true
Publication
First Author: Haarmann-Stemmann T
Year: 2007
Journal: Drug Metab Dispos
Title: Analysis of the transcriptional regulation and molecular function of the aryl hydrocarbon receptor repressor in human cell lines.
Volume: 35
Issue: 12
Pages: 2262-9