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Search results 301 to 318 out of 318 for Calm1

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Type Details Score
Allele
Name: calmodulin 1; endonuclease-mediated mutation 3, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
Strain
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
Strain
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
DO Term
Allele
Name: calmodulin 1; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
DO Term
Allele
Name: calmodulin 1; targeted mutation 1, Shanghai Model Organisms Center
Allele Type: Targeted
Attribute String: Not Specified
Publication
First Author: Chen Z
Year: 2017
Journal: Diabetes
Title: Hepatic Activation of the FAM3C-HSF1-CaM Pathway Attenuates Hyperglycemia of Obese Diabetic Mice.
Volume: 66
Issue: 5
Pages: 1185-1197
Strain
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
Publication
First Author: Zhao X
Year: 2018
Journal: Cell Biochem Funct
Title: ILEI is an important intermediate participating in the formation of TGF-β1-induced renal tubular EMT.
Volume: 36
Issue: 2
Pages: 46-55
Publication
First Author: Chen Z
Year: 2017
Journal: Oncotarget
Title: FAM3C activates HSF1 to suppress hepatic gluconeogenesis and attenuate hyperglycemia of type 1 diabetic mice.
Volume: 8
Issue: 62
Pages: 106038-106049
Protein Domain
Type: Family
Description: Protein FAM3C, also known as interleukin-like EMT inducer (ILEI), participates in the formation of TGF-beta1-induced renal tubular epithelial-to-mesenchymal transition (EMT) and has been linked to EMT in some diseases []. It is a hepatokine that suppresses hepatic gluconeogenic gene expression and insulin-independent gluconeogenesis by activating the HSF1-CaM-Akt pathway. It activates transcriptor heat shock factor 1 (HSF1) to induce CALM1 gene expression and increase calmodulin (CaM) protein level. An increase in CaM protein level suppresses glucose production by inducing Akt activation [, ].
Protein
Organism: Mus musculus/domesticus
Length: 110  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 99  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 227  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 303  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 247  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 197  
Fragment?: false