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Search results 301 to 386 out of 386 for Eif4ebp1

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Type Details Score
Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Allele
Eif4ebp1<em1Smoc> | MGI:7289468
Name: eukaryotic translation initiation factor 4E binding protein 1; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Strain
MGI:6428568 | C57BL/6J-Eif4Ebp1<em1Smoc>/Smoc
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Allele
Tg(CAG-GFP,-EIF4EBP1)2877Als | MGI:5896794
Name: transgene insertion 2877, Albert La Spada
Allele Type: Transgenic
Attribute String: Conditional ready, Humanized sequence, Inserted expressed sequence, Reporter
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Allele
Tg(CAG-GFP,-EIF4EBP1*)2969Als | MGI:5896791
Name: transgene insertion 2969, Albert La Spada
Allele Type: Transgenic
Attribute String: Conditional ready, Humanized sequence, Inserted expressed sequence, Reporter
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Strain
MGI:5896793 | B6.Cg-Tg(CAG-GFP,-EIF4EBP1*)2969Als/J
Attribute String: congenic, mutant strain, transgenic
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Strain
MGI:5896815 | B6.Cg-Tg(CAG-GFP,-EIF4EBP1)2877Als/J
Attribute String: transgenic, mutant strain, congenic
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Publication
31650481 | J:285112
First Author: Dai DF
Year: 2019
Journal: Geroscience
Title: Differential effects of various genetic mouse models of the mechanistic target of rapamycin complex I inhibition on heart failure.
Volume: 41
Issue: 6
Pages: 847-860
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Publication
15728574 | -
First Author: Yu Y
Year: 2005
Journal: J Biol Chem
Title: Structural basis for the unique biological function of small GTPase RHEB.
Volume: 280
Issue: 17
Pages: 17093-100
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Publication
12869586 | -
First Author: Inoki K
Year: 2003
Journal: Genes Dev
Title: Rheb GTPase is a direct target of TSC2 GAP activity and regulates mTOR signaling.
Volume: 17
Issue: 15
Pages: 1829-34
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Publication
15854902 | -
First Author: Long X
Year: 2005
Journal: Curr Biol
Title: Rheb binds and regulates the mTOR kinase.
Volume: 15
Issue: 8
Pages: 702-13
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Publication
16098514 | -
First Author: Tee AR
Year: 2005
Journal: FEBS Lett
Title: Analysis of mTOR signaling by the small G-proteins, Rheb and RhebL1.
Volume: 579
Issue: 21
Pages: 4763-8
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Publication
29104218 | -
 
First Author: Tatebe H
Year: 2017
Journal: Biomolecules
Title: Evolutionary Conservation of the Components in the TOR Signaling Pathways.
Volume: 7
Issue: 4
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Protein Domain
IPR037586 | RHEB
Type: Family
Description: Rheb is a Ras-like small GTPase essential for TORC1 activity in mammals []. Rheb activates the protein kinase activity of mTORC1 (rapamycin), and in turn stimulates the phosphorylation of S6K1 and EIF4EBP1 through activation of mTORC1 signaling [, , ]. Rheb alternates between an inactive form bound to GDP and an active form bound to GTP. It is inactivated by TSC1-TSC2 via the GTPase activating protein (GAP) domain of TSC2 []. The mechanism of action of Rheb has been determined from the tertiary structure [].
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HT Experiment
E-GEOD-23497 | Identification of genes that elicit disuse muscle atrophy via the transcription factors p50 and Bcl-3
Series Id: GSE23497
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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Publication
24728038 | J:213611
First Author: Han B
Year: 2014
Journal: Hum Mol Genet
Title: TGFBI (βIG-H3) is a diabetes-risk gene based on mouse and human genetic studies.
Volume: 23
Issue: 17
Pages: 4597-611
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Protein
B2RX86
Organism: Mus musculus/domesticus
Length: 563  
Fragment?: false
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Protein
Q3U5E2
Organism: Mus musculus/domesticus
Length: 478  
Fragment?: true
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Publication
8806680 | -
First Author: Wienecke R
Year: 1996
Journal: Oncogene
Title: Co-localization of the TSC2 product tuberin with its target Rap1 in the Golgi apparatus.
Volume: 13
Issue: 5
Pages: 913-23
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Protein Domain
IPR027107 | Tuberin/Ral-act_asu
Type: Family
Description: The activity of GTPases is regulated by the opposing effects of guanine nucleotide exchange factors (GEFs) and GTPase-activating proteins (GAPs). Tuberin (tuberous sclerosis 2 protein or Tsc2) is believed to be a tumor suppressor and is able to stimulate specific GTPases. It stimulates the intrinsic GTPase activity of the Ras-related protein Rap1A and Rab5 [, ]. In complex with Tsc1, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling. It acts as a GTPase-activating protein (GAP) for the small GTPase RheB, a direct activator of the protein kinase activity of mTORC1 [, ]. Ral GTPase-activating protein subunit alpha is the catalytic subunit of the heterodimeric RalGAP complex which acts as a GTPase activator for the Ras-like small GTPases RalA and RalB []. RalGAP complexes share structural and catalytic similarities with the tuberous sclerosis tumor suppressor complex [].
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Publication
21249144 | J:180832
First Author: Wu CL
Year: 2011
Journal: PLoS One
Title: Identification of genes that elicit disuse muscle atrophy via the transcription factors p50 and Bcl-3.
Volume: 6
Issue: 1
Pages: e16171
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Publication
31538542 | J:306961
First Author: Barroso-Chinea P
Year: 2020
Journal: Autophagy
Title: DRD3 (dopamine receptor D3) but not DRD2 activates autophagy through MTORC1 inhibition preserving protein synthesis.
Volume: 16
Issue: 7
Pages: 1279-1295
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Publication
19520869 | -
First Author: Shirakawa R
Year: 2009
Journal: J Biol Chem
Title: Tuberous sclerosis tumor suppressor complex-like complexes act as GTPase-activating proteins for Ral GTPases.
Volume: 284
Issue: 32
Pages: 21580-8
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Protein
A0A1W2P7Y4
Organism: Mus musculus/domesticus
Length: 172  
Fragment?: true
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Protein
A0A1W2P6Q0
Organism: Mus musculus/domesticus
Length: 49  
Fragment?: true
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Protein
A0A1W2P7P2
Organism: Mus musculus/domesticus
Length: 111  
Fragment?: true
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Protein
Q925J1
Organism: Mus musculus/domesticus
Length: 149  
Fragment?: true
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Publication
15340059 | -
First Author: Li Y
Year: 2004
Journal: Mol Cell Biol
Title: Biochemical and functional characterizations of small GTPase Rheb and TSC2 GAP activity.
Volume: 24
Issue: 18
Pages: 7965-75
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Publication
12271141 | -
First Author: Tee AR
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: Tuberous sclerosis complex-1 and -2 gene products function together to inhibit mammalian target of rapamycin (mTOR)-mediated downstream signaling.
Volume: 99
Issue: 21
Pages: 13571-6
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Protein
Q3TP98
Organism: Mus musculus/domesticus
Length: 207  
Fragment?: true
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Protein
Q3TQ10
Organism: Mus musculus/domesticus
Length: 237  
Fragment?: true
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Protein
Q6GYP7
Organism: Mus musculus/domesticus
Length: 2035  
Fragment?: false
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Protein
A3KGS3
Organism: Mus musculus/domesticus
Length: 1872  
Fragment?: false
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Protein
A0A2I3BRX9
Organism: Mus musculus/domesticus
Length: 2538  
Fragment?: false
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Protein
Q3UI96
Organism: Mus musculus/domesticus
Length: 621  
Fragment?: false
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Protein
A0A2I3BPE9
Organism: Mus musculus/domesticus
Length: 1359  
Fragment?: true
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Protein
A0A0A0MQD7
Organism: Mus musculus/domesticus
Length: 1910  
Fragment?: false
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Protein
A0A1W2P712
Organism: Mus musculus/domesticus
Length: 2082  
Fragment?: false
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Protein
Q3UG84
Organism: Mus musculus/domesticus
Length: 1359  
Fragment?: true
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Protein
Q3TBX9
Organism: Mus musculus/domesticus
Length: 1416  
Fragment?: true
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Protein
A0A2I3BPN8
Organism: Mus musculus/domesticus
Length: 1957  
Fragment?: false
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Protein
F7AI67
Organism: Mus musculus/domesticus
Length: 834  
Fragment?: true
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Protein
B7ZNA3
Organism: Mus musculus/domesticus
Length: 2082  
Fragment?: false
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Protein
A0A1W2P832
Organism: Mus musculus/domesticus
Length: 2082  
Fragment?: false
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Protein
F7CGP0
Organism: Mus musculus/domesticus
Length: 1567  
Fragment?: true
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Publication
9045618 | -
First Author: Xiao GH
Year: 1997
Journal: J Biol Chem
Title: The tuberous sclerosis 2 gene product, tuberin, functions as a Rab5 GTPase activating protein (GAP) in modulating endocytosis.
Volume: 272
Issue: 10
Pages: 6097-100
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Protein
Q61037
Organism: Mus musculus/domesticus
Length: 1814  
Fragment?: false
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Protein
Q3UHB2
Organism: Mus musculus/domesticus
Length: 1808  
Fragment?: false
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Protein
A0A2I3BRT5
Organism: Mus musculus/domesticus
Length: 1741  
Fragment?: false
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Protein
A0A2I3BPP1
Organism: Mus musculus/domesticus
Length: 1785  
Fragment?: false
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Protein
Q3TCQ7
Organism: Mus musculus/domesticus
Length: 1742  
Fragment?: false
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Protein
Q3UG88
Organism: Mus musculus/domesticus
Length: 1785  
Fragment?: false
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Protein
Q3UGI8
Organism: Mus musculus/domesticus
Length: 1678  
Fragment?: true
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Protein
Q7TT21
Organism: Mus musculus/domesticus
Length: 1742  
Fragment?: false
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Protein
Q921J2
Organism: Mus musculus/domesticus
Length: 184  
Fragment?: false
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Protein
Q9ESR1
Organism: Mus musculus/domesticus
Length: 184  
Fragment?: false
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Protein
Q540E6
Organism: Mus musculus/domesticus
Length: 184  
Fragment?: false
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom