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Search results 301 to 314 out of 314 for Gcgr

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GXD Expression

Probe:	MGI:5550066
Assay Type:	Immunohistochemistry
Annotation Date:	2014-03-10
Strength:	Present
Sex:	Not Specified
Emaps:	EMAPS:1750327
Pattern:	Not Specified
Stage:	TS27
Assay Id:	MGI:5550086
Age:	postnatal day 1

Note:	The number of cells co-expressing Nestin and Glucagon decreased abruptly and were not observed in the Gcgr mutant P1 islets.
Specimen Label:	not shown
Detected:	true
Specimen Num:	12

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Allele

Gcgr<em2Smoc> | MGI:6690504

Name:	glucagon receptor; endonuclease-mediated mutation 2, Shanghai Model Organisms Center
Allele Type:	Endonuclease-mediated
Attribute String:	Not Specified

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Allele

Gcgr<em4Smoc> | MGI:7278693

Name:	glucagon receptor; endonuclease-mediated mutation 4, Shanghai Model Organisms Center
Allele Type:	Endonuclease-mediated
Attribute String:	Conditional ready, No functional change

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GXD Expression

Probe:	MGI:5550066
Assay Type:	Immunohistochemistry
Annotation Date:	2014-03-10
Strength:	Present
Sex:	Not Specified
Emaps:	EMAPS:3532827
Pattern:	Not Specified
Stage:	TS27
Assay Id:	MGI:5550086
Age:	postnatal day 1

Note:	A large number of immunopositive cells were observed in the exocrine compartment of the Gcgr mutant. Co-expression with Amylase was noted.
Specimen Label:	not shown
Detected:	true
Specimen Num:	15

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Genotype

Symbol:	Gcgr/Gcgr
Background:	C57BL/6J-Gcgr
Zygosity:	hm
Has Mutant Allele:	true

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DO Term

DOID:0112306 | Mahvash Disease

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Publication

28650340 | J:246970

First Author:	Zhu L
Year:	2017
Journal:	J Clin Invest
Title:	Hepatic β-arrestin 2 is essential for maintaining euglycemia.
Volume:	127
Issue:	8
Pages:	2941-2945

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Publication

25675519 | J:220170

First Author:	Wang MY
Year:	2015
Journal:	Proc Natl Acad Sci U S A
Title:	Glucagon receptor antibody completely suppresses type 1 diabetes phenotype without insulin by disrupting a novel diabetogenic pathway.
Volume:	112
Issue:	8
Pages:	2503-8

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Publication

33411693 | J:306932

First Author:	Nason SR
Year:	2021
Journal:	JCI Insight
Title:	Glucagon receptor signaling regulates weight loss via central KLB receptor complexes.
Volume:	6
Issue:	4

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Publication

30582457 | J:295085

First Author:	Spolitu S
Year:	2019
Journal:	Circ Res
Title:	Hepatic Glucagon Signaling Regulates PCSK9 and Low-Density Lipoprotein Cholesterol.
Volume:	124
Issue:	1
Pages:	38-51

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Publication

25288673 | J:249693

First Author:	Jun LS
Year:	2015
Journal:	Diabetes
Title:	Absence of glucagon and insulin action reveals a role for the GLP-1 receptor in endogenous glucose production.
Volume:	64
Issue:	3
Pages:	819-27

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Publication

34337276 | J:309180

First Author:	Kjeldsen SAS
Year:	2021
Journal:	J Endocr Soc
Title:	Neprilysin Inhibition Increases Glucagon Levels in Humans and Mice With Potential Effects on Amino Acid Metabolism.
Volume:	5
Issue:	9
Pages:	bvab084

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Publication

32139602 | J:297296

First Author:	Lang S
Year:	2020
Journal:	BMJ Open Diabetes Res Care
Title:	Glucagon receptor antagonist upregulates circulating GLP-1 level by promoting intestinal L-cell proliferation and GLP-1 production in type 2 diabetes.
Volume:	8
Issue:	1

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Publication

26075596 | J:237818

First Author:	Han J
Year:	2015
Journal:	PLoS One
Title:	The Identification of Novel Protein-Protein Interactions in Liver that Affect Glucagon Receptor Activity.
Volume:	10
Issue:	6
Pages:	e0129226

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