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Search results 301 to 397 out of 397 for U2af1

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Type Details Score
Publication
17967808 | J:152068
First Author: Friedel RH
Year: 2007
Journal: Brief Funct Genomic Proteomic
Title: EUCOMM--the European conditional mouse mutagenesis program.
Volume: 6
Issue: 3
Pages: 180-5
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Publication
15618518 | J:91257
First Author: Gray PA
Year: 2004
Journal: Science
Title: Mouse brain organization revealed through direct genome-scale TF expression analysis.
Volume: 306
Issue: 5705
Pages: 2255-7
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Publication
12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
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Publication
- | J:57656
     
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:171409
     
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
31011167 | J:282896
First Author: Smith MA
Year: 2019
Journal: Nat Cell Biol
Title: U2AF1 mutations induce oncogenic IRAK4 isoforms and activate innate immune pathways in myeloid malignancies.
Volume: 21
Issue: 5
Pages: 640-650
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Publication
27566151 | J:250265
First Author: Kralovicova J
Year: 2017
Journal: Nucleic Acids Res
Title: Alternative splicing of U2AF1 reveals a shared repression mechanism for duplicated exons.
Volume: 45
Issue: 1
Pages: 417-434
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Publication
25311244 | -
First Author: Okeyo-Owuor T
Year: 2015
Journal: Leukemia
Title: U2AF1 mutations alter sequence specificity of pre-mRNA binding and splicing.
Volume: 29
Issue: 4
Pages: 909-17
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Allele
U2af1<em2Smoc> | MGI:7293055
Name: U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 1; endonuclease-mediated mutation 2, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
Col1a1<tm2(tetO-U2AF1)Mjwa> | MGI:5752390
Name: collagen, type I, alpha 1; targeted mutation 2, Matthew J Walter
Allele Type: Targeted
Attribute String: Inducible, Inserted expressed sequence
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Strain
MGI:6771248 | C57BL/6-U2af1<em2Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Allele
Col1a1<tm1(tetO-U2AF1*S34F)Mjwa> | MGI:5752388
Name: collagen, type I, alpha 1; targeted mutation 1, Matthew J Walter
Allele Type: Targeted
Attribute String: Inducible, Inserted expressed sequence
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Allele
U2af1<em1Smoc> | MGI:7293054
Name: U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 1; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Strain
MGI:6476572 | C57BL/6J-U2af1<em1Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Allele
Dp(17Abcg1-Cbs)1Yah | MGI:4367905
 
Name: duplication, Chr 17, Yann Herault 1
Allele Type: Targeted
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Allele
Del(17Abcg1-Cbs)2Yah | MGI:4367904
 
Name: deletion, Chr 17, Yann Herault 2
Allele Type: Targeted
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Strain
MGI:5903487 | B6.Cg-Gt(ROSA)26Sor<tm1(rtTA*M2)Jae> Col1a1<tm1(tetO-U2AF1*S34F)Mjwa>/J
Attribute String: targeted mutation, mutant strain, congenic
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Strain
MGI:4368000 | B6.129P2-Dp(17Abcg1-Cbs1)1Yah
Attribute String: targeted mutation, mutant strain, insertion, deletion, chromosome aberration
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Strain
MGI:4834808 | B6;129P2-Dp(17Abcg1-Cbs)1Yah/Orl
Attribute String: duplication, mutant stock, targeted mutation, chromosome aberration
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Publication
24752061 | J:214512
First Author: Sahún I
Year: 2014
Journal: Genetics
Title: Cognition and hippocampal plasticity in the mouse is altered by monosomy of a genomic region implicated in Down syndrome.
Volume: 197
Issue: 3
Pages: 899-912
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Strain
MGI:4367999 | B6.129P2-Del(17Abcg1-Cbs)2Yah
Attribute String: congenic, mutant strain, targeted mutation, chromosome aberration, deletion, insertion
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Strain
MGI:4834807 | B6;129P2-Del(17Abcg1-Cbs)2Yah/Orl
Attribute String: mutant stock, targeted mutation, deletion, chromosome aberration
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Genotype
Genotype
Symbol: Dp(17Abcg1-Cbs)1Yah/?
Background: B6.129P2-Dp(17Abcg1-Cbs1)1Yah
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Del(17Abcg1-Cbs)2Yah/+
Background: B6.129P2-Del(17Abcg1-Cbs)2Yah
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Col1a1/Col1a1<+> Gt(ROSA)26Sor/?
Background: involves: 129S4/SvJae * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Col1a1/Col1a1<+> Gt(ROSA)26Sor/?
Background: involves: 129S4/SvJae * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Publication
31439048 | J:293382
First Author: Bereshchenko O
Year: 2019
Journal: Clin Epigenetics
Title: Deficiency and haploinsufficiency of histone macroH2A1.1 in mice recapitulate hematopoietic defects of human myelodysplastic syndrome.
Volume: 11
Issue: 1
Pages: 121
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Publication
37612136 | J:341536
First Author: Shimazu T
Year: 2023
Journal: Genes Dev
Title: Histidine N1-position-specific methyltransferase CARNMT1 targets C3H zinc finger proteins and modulates RNA metabolism.
Volume: 37
Issue: 15-16
Pages: 724-742
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Protein
B1B0F1
Organism: Mus musculus/domesticus
Length: 71  
Fragment?: true
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Protein
Q3TN32
Organism: Mus musculus/domesticus
Length: 82  
Fragment?: true
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Protein
B1B0F0
Organism: Mus musculus/domesticus
Length: 113  
Fragment?: true
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Protein
B1B0E9
Organism: Mus musculus/domesticus
Length: 144  
Fragment?: false
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Publication
8630064 | J:32959
First Author: Pearsall RS
Year: 1996
Journal: Biochem Biophys Res Commun
Title: Absence of imprinting in U2AFBPL, a human homologue of the imprinted mouse gene U2afbp-rs.
Volume: 222
Issue: 1
Pages: 171-7
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Publication
1824937 | -
First Author: Zamore PD
Year: 1991
Journal: EMBO J
Title: Biochemical characterization of U2 snRNP auxiliary factor: an essential pre-mRNA splicing factor with a novel intranuclear distribution.
Volume: 10
Issue: 1
Pages: 207-14
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Publication
2531895 | -
First Author: Zamore PD
Year: 1989
Journal: Proc Natl Acad Sci U S A
Title: Identification, purification, and biochemical characterization of U2 small nuclear ribonucleoprotein auxiliary factor.
Volume: 86
Issue: 23
Pages: 9243-7
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Publication
9632785 | -
First Author: Rudner DZ
Year: 1998
Journal: Mol Cell Biol
Title: RNA binding activity of heterodimeric splicing factor U2AF: at least one RS domain is required for high-affinity binding.
Volume: 18
Issue: 7
Pages: 4004-11
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Protein Domain
IPR009145 | U2AF_small
Type: Family
Description: The U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) is a heterodimeric splicing factor composed of a large and a small subunit []. The large U2AF subunit recognises the intronic polypyrimidine tract, a sequence located adjacent to the 3' splice site that serves as an important signal for both constitutive and regulated pre-mRNA splicing. The small subunit interacts with the 3' splice site dinucleotide AG and is essential for regulated splicing. The subunits shuttle continuously between the nucleus and the cytoplasm via a mechanism that involves carrier receptors and is independent of binding to mRNA. Both subunits contain an arginine/serine-rich (RS) domain, which acts as a nuclear localisation signal.Furthermore, the presence of an RS domain on either subunit is sufficient to trigger the nucleocytoplasmic import of the heterodimeric complex [, , ].The human form of the U2 auxiliary factor small subunit, hU2AF35, contains a degenerate RNA recognition motif (RRM) and a C-terminal RS domain. Mutations in this protein alters U2AF1 function affects the alternative splicing of target genes associated with myelodysplastic syndrome (MDS) []. The murine form has been shown to be genomically imprinted with monoallelic expression from the paternal allele. However, this is not the case in humans [].
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Publication
30649339 | J:273645
First Author: Marechal D
Year: 2019
Journal: Hum Mol Genet
Title: Cbs overdosage is necessary and sufficient to induce cognitive phenotypes in mouse models of Down syndrome and interacts genetically with Dyrk1a.
Volume: 28
Issue: 9
Pages: 1561-1577
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Publication
27622329 | J:234979
First Author: Inoue D
Year: 2016
Journal: Cancer Cell
Title: Modeling SF3B1 Mutations in Cancer: Advances, Challenges, and Opportunities.
Volume: 30
Issue: 3
Pages: 371-373
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Publication
22126738 | J:196862
First Author: Zhang L
Year: 2012
Journal: Bioeng Bugs
Title: Genetic analysis of Down syndrome facilitated by mouse chromosome engineering.
Volume: 3
Issue: 1
Pages: 8-12
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Publication
27538963 | J:242664
First Author: Gupta M
Year: 2016
Journal: Mamm Genome
Title: Mouse models of Down syndrome: gene content and consequences.
Volume: 27
Issue: 11-12
Pages: 538-555
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Publication
12374752 | -
First Author: Huang T
Year: 2002
Journal: EMBO J
Title: Pre-spliceosome formation in S.pombe requires a stable complex of SF1-U2AF(59)-U2AF(23).
Volume: 21
Issue: 20
Pages: 5516-26
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Protein
A0A494B9X9
Organism: Mus musculus/domesticus
Length: 75  
Fragment?: false
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Protein
F7D8X7
Organism: Mus musculus/domesticus
Length: 53  
Fragment?: true
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Protein
A0A494BA95
Organism: Mus musculus/domesticus
Length: 45  
Fragment?: false
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Protein
E9Q809
Organism: Mus musculus/domesticus
Length: 102  
Fragment?: false
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Protein
E9PUZ3
Organism: Mus musculus/domesticus
Length: 187  
Fragment?: false
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Protein
A0A140LHB1
Organism: Mus musculus/domesticus
Length: 120  
Fragment?: true
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Protein
A0A140LII3
Organism: Mus musculus/domesticus
Length: 90  
Fragment?: false
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Protein
F8WH71
Organism: Mus musculus/domesticus
Length: 146  
Fragment?: false
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Protein
Q62377
Organism: Mus musculus/domesticus
Length: 462  
Fragment?: false
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Protein
Q8BGJ9
Organism: Mus musculus/domesticus
Length: 220  
Fragment?: false
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Protein
Q9D883
Organism: Mus musculus/domesticus
Length: 239  
Fragment?: false
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Protein
Q64707
Organism: Mus musculus/domesticus
Length: 428  
Fragment?: false
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Protein
A0A494B947
Organism: Mus musculus/domesticus
Length: 126  
Fragment?: true
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Protein
Q14C24
Organism: Mus musculus/domesticus
Length: 239  
Fragment?: false
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Protein
G3UW94
Organism: Mus musculus/domesticus
Length: 239  
Fragment?: false
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Protein
E9Q1I7
Organism: Mus musculus/domesticus
Length: 210  
Fragment?: false
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Protein
E9PWA1
Organism: Mus musculus/domesticus
Length: 105  
Fragment?: true
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Protein
B1B0E8
Organism: Mus musculus/domesticus
Length: 541  
Fragment?: false
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Protein
Q99L29
Organism: Mus musculus/domesticus
Length: 310  
Fragment?: false
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Protein
E9Q5J3
Organism: Mus musculus/domesticus
Length: 216  
Fragment?: false
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Protein
E9Q3S9
Organism: Mus musculus/domesticus
Length: 119  
Fragment?: true
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Protein
E9Q5Y2
Organism: Mus musculus/domesticus
Length: 181  
Fragment?: false
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Protein
A0A140LII6
Organism: Mus musculus/domesticus
Length: 122  
Fragment?: false
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Protein
Q8BST8
Organism: Mus musculus/domesticus
Length: 428  
Fragment?: false
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Protein
Q793C9
Organism: Mus musculus/domesticus
Length: 428  
Fragment?: false
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
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