Type |
Details |
Score |
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
542
|
Fragment?: |
false |
|
•
•
•
•
•
|
Allele |
Name: |
calcium/calmodulin-dependent protein kinase II, delta; endonuclease-mediated mutation 1, Shanghai Model Organisms Center |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Conditional ready, No functional change |
|
•
•
•
•
•
|
Allele |
Name: |
transgene insertion 1, Xiang-Dong Fu |
Allele Type: |
Transgenic |
Attribute String: |
Inserted expressed sequence |
|
•
•
•
•
•
|
Allele |
Name: |
transgene insertion 1, Masafumi Yano |
Allele Type: |
Transgenic |
Attribute String: |
Inserted expressed sequence |
|
•
•
•
•
•
|
Allele |
Name: |
transgene insertion 1, Joan Heller Brown |
Allele Type: |
Transgenic |
Attribute String: |
Inserted expressed sequence |
|
•
•
•
•
•
|
Allele |
Name: |
transgene insertion, Joan Heller Brown |
Allele Type: |
Transgenic |
Attribute String: |
Inserted expressed sequence |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Tg(Myh6-Camk2d)1Xdfu/? |
Background: |
Not Specified |
Zygosity: |
ot |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Wagner S |
Year: |
2006 |
Journal: |
J Clin Invest |
Title: |
Ca2+/calmodulin-dependent protein kinase II regulates cardiac Na+ channels. |
Volume: |
116 |
Issue: |
12 |
Pages: |
3127-38 |
|
•
•
•
•
•
|
Allele |
Name: |
transgene insertion L, Joan Heller Brown |
Allele Type: |
Transgenic |
Attribute String: |
Inserted expressed sequence |
|
•
•
•
•
•
|
Allele |
Name: |
transgene insertion M, Joan Heller Brown |
Allele Type: |
Transgenic |
Attribute String: |
Inserted expressed sequence |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Tg(Myh6-Camk2d)1Jhb/? |
Background: |
involves: C57BL/6 |
Zygosity: |
ot |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Tg(Myh6-Camk2d_ic)#Jhb/? |
Background: |
Not Specified |
Zygosity: |
ot |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
HT Experiment |
|
Experiment Type: |
RNA-Seq |
Study Type: |
WT vs. Mutant |
Source: |
GEO |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang T |
Year: |
2007 |
Journal: |
J Biol Chem |
Title: |
CaMKIIdelta isoforms differentially affect calcium handling but similarly regulate HDAC/MEF2 transcriptional responses. |
Volume: |
282 |
Issue: |
48 |
Pages: |
35078-87 |
|
•
•
•
•
•
|
Publication |
First Author: |
Maier LS |
Year: |
2003 |
Journal: |
Circ Res |
Title: |
Transgenic CaMKIIdeltaC overexpression uniquely alters cardiac myocyte Ca2+ handling: reduced SR Ca2+ load and activated SR Ca2+ release. |
Volume: |
92 |
Issue: |
8 |
Pages: |
904-11 |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Tg(Myh6-Camk2d_ic)MJhb/? |
Background: |
either: (involves: Black Swiss) or (involves: C57BL/6) |
Zygosity: |
ot |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Tg(Myh6-Camk2d_ic)LJhb/? |
Background: |
either: (involves: Black Swiss) or (involves: C57BL/6) |
Zygosity: |
ot |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Bengel P |
Year: |
2021 |
Journal: |
Nat Commun |
Title: |
Detrimental proarrhythmogenic interaction of Ca2+/calmodulin-dependent protein kinase II and NaV1.8 in heart failure. |
Volume: |
12 |
Issue: |
1 |
Pages: |
6586 |
|
•
•
•
•
•
|
Publication |
First Author: |
Beraldi R |
Year: |
2014 |
Journal: |
Hum Mol Genet |
Title: |
Rbm20-deficient cardiogenesis reveals early disruption of RNA processing and sarcomere remodeling establishing a developmental etiology for dilated cardiomyopathy. |
Volume: |
23 |
Issue: |
14 |
Pages: |
3779-91 |
|
•
•
•
•
•
|
Publication |
First Author: |
Xu Q |
Year: |
2016 |
Journal: |
Cell Death Dis |
Title: |
Long non-coding RNA C2dat1 regulates CaMKIIδ expression to promote neuronal survival through the NF-κB signaling pathway following cerebral ischemia. |
Volume: |
7 |
Issue: |
3 |
Pages: |
e2173 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lebek S |
Year: |
2024 |
Journal: |
J Clin Invest |
Title: |
CRISPR-Cas9 base editing of pathogenic CaMKIIδ improves cardiac function in a humanized mouse model. |
Volume: |
134 |
Issue: |
1 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
van den Hoogenhof MMG |
Year: |
2018 |
Journal: |
Circulation |
Title: |
RBM20 Mutations Induce an Arrhythmogenic Dilated Cardiomyopathy Related to Disturbed Calcium Handling. |
Volume: |
138 |
Issue: |
13 |
Pages: |
1330-1342 |
|
•
•
•
•
•
|