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Search results 401 to 495 out of 495 for Fap

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Type Details Score
Publication
First Author: Cai F
Year: 2013
Journal: BMB Rep
Title: Short hairpin RNA targeting of fibroblast activation protein inhibits tumor growth and improves the tumor microenvironment in a mouse model.
Volume: 46
Issue: 5
Pages: 252-7
Publication  
First Author: Keane FM
Year: 2013
Journal: FEBS Open Bio
Title: Quantitation of fibroblast activation protein (FAP)-specific protease activity in mouse, baboon and human fluids and organs.
Volume: 4
Pages: 43-54
DO Term
Interaction Experiment
Description: The FAP motif within human ATG7, an autophagy-related E1-like enzyme, is essential for the E2-substrate reaction of LC3 lipidation.
Allele
Name: fibroblast activation protein; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
Publication
First Author: Tanida I
Year: 2012
Journal: Autophagy
Title: The FAP motif within human ATG7, an autophagy-related E1-like enzyme, is essential for the E2-substrate reaction of LC3 lipidation.
Volume: 8
Issue: 1
Pages: 88-97
Protein
Organism: Mus musculus/domesticus
Length: 736  
Fragment?: true
Strain
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
Allele
Name: transgene insertion M, Raghu Kalluri
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Allele
Name: transgene insertion, Douglas T Fearon
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Allele
Name: transgene insertion, Douglas T Fearon
Allele Type: Transgenic
Attribute String: Reporter
Strain
Attribute String: mutant strain, transgenic, congenic
Strain
Attribute String: transgenic, mutant strain, congenic
Publication
First Author: Fujita Y
Year: 2007
Journal: Mol Microbiol
Title: Regulation of fatty acid metabolism in bacteria.
Volume: 66
Issue: 4
Pages: 829-39
Publication
First Author: Schujman GE
Year: 2003
Journal: Dev Cell
Title: FapR, a bacterial transcription factor involved in global regulation of membrane lipid biosynthesis.
Volume: 4
Issue: 5
Pages: 663-72
Protein Domain
Type: Family
Description: This entry represents the transcription factor FapR, which is involved in the regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism []. FapR controls the expression of many genes involved in fatty acid and phospholipid metabolism (the fap regulon)[].
Allele
Name: transgene insertion, Raghu Kalluri
Allele Type: Transgenic
Attribute String: Recombinase
Publication  
First Author: Pratt CP
Year: 2017
Journal: Front Cell Neurosci
Title: Tagging of Endogenous BK Channels with a Fluorogen-Activating Peptide Reveals β4-Mediated Control of Channel Clustering in Cerebellum.
Volume: 11
Pages: 337
Allele
Name: potassium large conductance calcium-activated channel, subfamily M, alpha member 1; endonuclease-mediated mutation 1, Gregg E Homanics
Allele Type: Endonuclease-mediated
Attribute String: Epitope tag, Humanized sequence
HT Experiment  
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
Strain
Attribute String: mutant strain, endonuclease-mediated mutation
Publication
First Author: Su LK
Year: 1992
Journal: Science
Title: Multiple intestinal neoplasia caused by a mutation in the murine homolog of the APC gene.
Volume: 256
Issue: 5057
Pages: 668-70
Publication
First Author: Yang K
Year: 1998
Journal: Cancer Res
Title: Dietary modulation of carcinoma development in a mouse model for human familial adenomatous polyposis.
Volume: 58
Issue: 24
Pages: 5713-7
Publication
First Author: Feig C
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Targeting CXCL12 from FAP-expressing carcinoma-associated fibroblasts synergizes with anti-PD-L1 immunotherapy in pancreatic cancer.
Volume: 110
Issue: 50
Pages: 20212-7
Publication
First Author: Cai J
Year: 2015
Journal: Genes Dev
Title: β-Catenin destruction complex-independent regulation of Hippo-YAP signaling by APC in intestinal tumorigenesis.
Volume: 29
Issue: 14
Pages: 1493-506
Publication
First Author: Uapinyoying P
Year: 2023
Journal: iScience
Title: Single-cell transcriptomic analysis of the identity and function of fibro/adipogenic progenitors in healthy and dystrophic muscle.
Volume: 26
Issue: 8
Pages: 107479
Publication  
First Author: Marinkovic M
Year: 2019
Journal: Life Sci Alliance
Title: Fibro-adipogenic progenitors of dystrophic mice are insensitive to NOTCH regulation of adipogenesis.
Volume: 2
Issue: 3
Publication  
First Author: Biferali B
Year: 2021
Journal: Sci Adv
Title: Prdm16-mediated H3K9 methylation controls fibro-adipogenic progenitors identity during skeletal muscle repair.
Volume: 7
Issue: 23
Publication
First Author: Kopinke D
Year: 2017
Journal: Cell
Title: Ciliary Hedgehog Signaling Restricts Injury-Induced Adipogenesis.
Volume: 170
Issue: 2
Pages: 340-351.e12
Publication
First Author: López-Arribillaga E
Year: 2018
Journal: Nat Commun
Title: Manic Fringe deficiency imposes Jagged1 addiction to intestinal tumor cells.
Volume: 9
Issue: 1
Pages: 2992
Publication
First Author: Hogarth MW
Year: 2019
Journal: Nat Commun
Title: Fibroadipogenic progenitors are responsible for muscle loss in limb girdle muscular dystrophy 2B.
Volume: 10
Issue: 1
Pages: 2430
Publication
First Author: Sasaki H
Year: 1986
Journal: Biochem Biophys Res Commun
Title: Generation of transgenic mice producing a human transthyretin variant: a possible mouse model for familial amyloidotic polyneuropathy.
Volume: 139
Issue: 2
Pages: 794-9
Publication
First Author: Li B
Year: 2014
Journal: PLoS One
Title: Repurposing the FDA-approved pinworm drug pyrvinium as a novel chemotherapeutic agent for intestinal polyposis.
Volume: 9
Issue: 7
Pages: e101969
Publication
First Author: Dang DT
Year: 2000
Journal: FEBS Lett
Title: Decreased expression of the gut-enriched Krüppel-like factor gene in intestinal adenomas of multiple intestinal neoplasia mice and in colonic adenomas of familial adenomatous polyposis patients.
Volume: 476
Issue: 3
Pages: 203-7
Publication
First Author: Shibata H
Year: 1997
Journal: Science
Title: Rapid colorectal adenoma formation initiated by conditional targeting of the Apc gene.
Volume: 278
Issue: 5335
Pages: 120-3
Publication
First Author: Saito Y
Year: 2020
Journal: Nat Commun
Title: Exercise enhances skeletal muscle regeneration by promoting senescence in fibro-adipogenic progenitors.
Volume: 11
Issue: 1
Pages: 889
Publication
First Author: Gui J
Year: 2020
Journal: Nat Cancer
Title: Activation of p38α stress-activated protein kinase drives the formation of the pre-metastatic niche in the lungs.
Volume: 1
Issue: 6
Pages: 603-619
Publication
First Author: Hiraishi Y
Year: 2018
Journal: Sci Rep
Title: IL-33, IL-25 and TSLP contribute to development of fungal-associated protease-induced innate-type airway inflammation.
Volume: 8
Issue: 1
Pages: 18052
Publication
First Author: Powell AE
Year: 2014
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Inducible loss of one Apc allele in Lrig1-expressing progenitor cells results in multiple distal colonic tumors with features of familial adenomatous polyposis.
Volume: 307
Issue: 1
Pages: G16-23
Publication
First Author: Sastourné-Arrey Q
Year: 2023
Journal: Nat Commun
Title: Adipose tissue is a source of regenerative cells that augment the repair of skeletal muscle after injury.
Volume: 14
Issue: 1
Pages: 80
Publication
First Author: Phelps M
Year: 2016
Journal: FEBS J
Title: Expression profile and overexpression outcome indicate a role for βKlotho in skeletal muscle fibro/adipogenesis.
Volume: 283
Issue: 9
Pages: 1653-68
Publication
First Author: Mazur A
Year: 2016
Journal: PLoS One
Title: Cleavage of Type I Collagen by Fibroblast Activation Protein-α Enhances Class A Scavenger Receptor Mediated Macrophage Adhesion.
Volume: 11
Issue: 3
Pages: e0150287
Publication  
First Author: Gonçalves NP
Year: 2016
Journal: Neurobiol Aging
Title: Tissue remodeling after interference RNA mediated knockdown of transthyretin in a familial amyloidotic polyneuropathy mouse model.
Volume: 47
Pages: 91-101
Publication
First Author: Cho C
Year: 2020
Journal: Oncogene
Title: Cancer-associated fibroblasts downregulate type I interferon receptor to stimulate intratumoral stromagenesis.
Volume: 39
Issue: 38
Pages: 6129-6137
Publication
First Author: Cho JM
Year: 2020
Journal: Sci Rep
Title: Discovery of a novel fibroblast activation protein (FAP) inhibitor, BR103354, with anti-diabetic and anti-steatotic effects.
Volume: 10
Issue: 1
Pages: 21280
Publication  
First Author: Lees-Shepard JB
Year: 2022
Journal: J Clin Invest
Title: An anti-ACVR1 antibody exacerbates heterotopic ossification by fibro-adipogenic progenitors in fibrodysplasia ossificans progressiva mice.
Volume: 132
Issue: 12
Publication  
First Author: Mázala DA
Year: 2020
Journal: JCI Insight
Title: TGF-β-driven muscle degeneration and failed regeneration underlie disease onset in a DMD mouse model.
Volume: 5
Issue: 6
Publication  
First Author: Reggio A
Year: 2020
Journal: Life Sci Alliance
Title: Metabolic reprogramming of fibro/adipogenic progenitors facilitates muscle regeneration.
Volume: 3
Issue: 3
Publication
First Author: Saccone V
Year: 2014
Journal: Genes Dev
Title: HDAC-regulated myomiRs control BAF60 variant exchange and direct the functional phenotype of fibro-adipogenic progenitors in dystrophic muscles.
Volume: 28
Issue: 8
Pages: 841-57
Publication
First Author: Lemos DR
Year: 2012
Journal: Stem Cells
Title: Functionally convergent white adipogenic progenitors of different lineages participate in a diffused system supporting tissue regeneration.
Volume: 30
Issue: 6
Pages: 1152-62
Publication
First Author: Cordani N
Year: 2014
Journal: Stem Cells
Title: Nitric oxide controls fat deposition in dystrophic skeletal muscle by regulating fibro-adipogenic precursor differentiation.
Volume: 32
Issue: 4
Pages: 874-85
Publication
First Author: Sodir NM
Year: 2006
Journal: Cancer Res
Title: Smad3 deficiency promotes tumorigenesis in the distal colon of ApcMin/+ mice.
Volume: 66
Issue: 17
Pages: 8430-8
Publication  
First Author: Li Z
Year: 2022
Journal: Biochem Biophys Res Commun
Title: TTR exon-humanized mouse optimal for verifying new therapies for FAP.
Volume: 599
Pages: 69-74
Publication  
First Author: Gonçalves NP
Year: 2014
Journal: Exp Neurol
Title: The inflammatory response to sciatic nerve injury in a familial amyloidotic polyneuropathy mouse model.
Volume: 257
Pages: 76-87
Publication
First Author: Santos SD
Year: 2007
Journal: J Pathol
Title: Impairment of the ubiquitin-proteasome system associated with extracellular transthyretin aggregates in familial amyloidotic polyneuropathy.
Volume: 213
Issue: 2
Pages: 200-9
Publication
First Author: Nakanishi M
Year: 2018
Journal: Carcinogenesis
Title: A novel bioactive derivative of eicosapentaenoic acid (EPA) suppresses intestinal tumor development in ApcΔ14/+ mice.
Volume: 39
Issue: 3
Pages: 429-438
Publication
First Author: Shelton DN
Year: 2006
Journal: Cancer Res
Title: Up-regulation of CYP26A1 in adenomatous polyposis coli-deficient vertebrates via a WNT-dependent mechanism: implications for intestinal cell differentiation and colon tumor development.
Volume: 66
Issue: 15
Pages: 7571-7
Publication
First Author: Gerner EW
Year: 2007
Journal: Biochem Soc Trans
Title: Impact of dietary amino acids and polyamines on intestinal carcinogenesis and chemoprevention in mouse models.
Volume: 35
Issue: Pt 2
Pages: 322-5
Publication  
First Author: Liu Z
Year: 2016
Journal: Mol Cell Endocrinol
Title: Extensive metabolic disorders are present in APC(min) tumorigenesis mice.
Volume: 427
Pages: 57-64
Publication
First Author: Smits R
Year: 1998
Journal: Gastroenterology
Title: Apc1638N: a mouse model for familial adenomatous polyposis-associated desmoid tumors and cutaneous cysts.
Volume: 114
Issue: 2
Pages: 275-83
Publication
First Author: Paulsen JE
Year: 2000
Journal: Scand J Gastroenterol
Title: Identification and quantification of aberrant crypt foci in the colon of Min mice--a murine model of familial adenomatous polyposis.
Volume: 35
Issue: 5
Pages: 534-9
Publication
First Author: Knutsen HK
Year: 2005
Journal: Anticancer Res
Title: Increased levels of PPARbeta/delta and cyclin D1 in flat dysplastic ACF and adenomas in Apc(Min/+) mice.
Volume: 25
Issue: 6B
Pages: 3781-9
Publication
First Author: Husøy T
Year: 2005
Journal: Int J Cancer
Title: Connexin43 is overexpressed in Apc(Min/+)-mice adenomas and colocalises with COX-2 in myofibroblasts.
Volume: 116
Issue: 3
Pages: 351-8
Publication
First Author: Lang M
Year: 2017
Journal: Cancer Res
Title: HuR Small-Molecule Inhibitor Elicits Differential Effects in Adenomatosis Polyposis and Colorectal Carcinogenesis.
Volume: 77
Issue: 9
Pages: 2424-2438
Publication
First Author: Erdman SH
Year: 1999
Journal: Carcinogenesis
Title: APC-dependent changes in expression of genes influencing polyamine metabolism, and consequences for gastrointestinal carcinogenesis, in the Min mouse.
Volume: 20
Issue: 9
Pages: 1709-13
Publication
First Author: Yang K
Year: 2003
Journal: Carcinogenesis
Title: Regional response leading to tumorigenesis after sulindac in small and large intestine of mice with Apc mutations.
Volume: 24
Issue: 3
Pages: 605-11
Publication
First Author: Mueller AA
Year: 2016
Journal: Nature
Title: Intronic polyadenylation of PDGFRα in resident stem cells attenuates muscle fibrosis.
Volume: 540
Issue: 7632
Pages: 276-279
Publication
First Author: Fodde R
Year: 1999
Journal: Cytogenet Cell Genet
Title: Mechanisms of APC-driven tumorigenesis: lessons from mouse models.
Volume: 86
Issue: 2
Pages: 105-11
Publication  
First Author: Olschwang S
Year: 1999
Journal: Eur J Cancer Prev
Title: Germline mutation and genome instability.
Volume: 8 Suppl 1
Pages: S33-7
Publication
First Author: Nakamura Y
Year: 1988
Journal: Am J Hum Genet
Title: Localization of the genetic defect in familial adenomatous polyposis within a small region of chromosome 5.
Volume: 43
Issue: 5
Pages: 638-44
Publication
First Author: Takaoka Y
Year: 2004
Journal: Am J Pathol
Title: Cysteine 10 is a key residue in amyloidogenesis of human transthyretin Val30Met.
Volume: 164
Issue: 1
Pages: 337-45
Publication
First Author: Plasilova M
Year: 2004
Journal: Eur J Hum Genet
Title: Exclusion of an extracolonic disease modifier locus on chromosome 1p33-36 in a large Swiss familial adenomatous polyposis kindred.
Volume: 12
Issue: 5
Pages: 365-71
Publication
First Author: Leedham SJ
Year: 2005
Journal: Stem Cell Rev
Title: Gastrointestinal stem cells and cancer: bridging the molecular gap.
Volume: 1
Issue: 3
Pages: 233-41
Publication
First Author: Uckun FM
Year: 2007
Journal: Arzneimittelforschung
Title: Effect of targeting janus kinase 3 on the development of intestinal tumors in the adenomatous polyposis coli(min) mouse model of familial adenomatous polyposis.
Volume: 57
Issue: 6
Pages: 320-9
Publication
First Author: Heinen CD
Year: 2010
Journal: Mutat Res
Title: Genotype to phenotype: analyzing the effects of inherited mutations in colorectal cancer families.
Volume: 693
Issue: 1-2
Pages: 32-45
Publication
First Author: Misumi Y
Year: 2013
Journal: Lab Invest
Title: Fibroblasts endocytose and degrade transthyretin aggregates in transthyretin-related amyloidosis.
Volume: 93
Issue: 8
Pages: 911-20
Publication
First Author: Zhen EY
Year: 2016
Journal: Biochem J
Title: Circulating FGF21 proteolytic processing mediated by fibroblast activation protein.
Volume: 473
Issue: 5
Pages: 605-14
Publication
First Author: Ishikawa A
Year: 2017
Journal: PLoS One
Title: Identification of a Putative Quantitative Trait Gene for Resistance to Obesity in Mice Using Transcriptome Analysis and Causal Inference Tests.
Volume: 12
Issue: 1
Pages: e0170652
Publication  
First Author: Huang YW
Year: 2020
Journal: Front Immunol
Title: Black Raspberries Suppress Colorectal Cancer by Enhancing Smad4 Expression in Colonic Epithelium and Natural Killer Cells.
Volume: 11
Pages: 570683
Publication
First Author: Bommi PV
Year: 2021
Journal: Cancer Res
Title: The Transcriptomic Landscape of Mismatch Repair-Deficient Intestinal Stem Cells.
Volume: 81
Issue: 10
Pages: 2760-2773
Publication
First Author: Giuliani G
Year: 2021
Journal: Cell Death Dis
Title: SCA-1 micro-heterogeneity in the fate decision of dystrophic fibro/adipogenic progenitors.
Volume: 12
Issue: 1
Pages: 122
Publication
First Author: Hardiman KM
Year: 2014
Journal: PLoS One
Title: Rapamycin inhibition of polyposis and progression to dysplasia in a mouse model.
Volume: 9
Issue: 4
Pages: e96023
Publication
First Author: Suzui M
Year: 2002
Journal: Cancer Lett
Title: Enhanced colon carcinogenesis induced by azoxymethane in min mice occurs via a mechanism independent of beta-catenin mutation.
Volume: 183
Issue: 1
Pages: 31-41
Publication
First Author: You S
Year: 2006
Journal: Int J Exp Pathol
Title: Developmental abnormalities in multiple proliferative tissues of Apc(Min/+) mice.
Volume: 87
Issue: 3
Pages: 227-36
Publication
First Author: Wasan HS
Year: 1998
Journal: J Pathol
Title: APC in the regulation of intestinal crypt fission.
Volume: 185
Issue: 3
Pages: 246-55
Publication
First Author: Zhang T
Year: 1997
Journal: Cancer Res
Title: Concurrent overexpression of cyclin D1 and cyclin-dependent kinase 4 (Cdk4) in intestinal adenomas from multiple intestinal neoplasia (Min) mice and human familial adenomatous polyposis patients.
Volume: 57
Issue: 1
Pages: 169-75
Publication
First Author: Crist RC
Year: 2010
Journal: Mamm Genome
Title: The armadillo repeat domain of Apc suppresses intestinal tumorigenesis.
Volume: 21
Issue: 9-10
Pages: 450-7
Publication
First Author: Firestone RS
Year: 2021
Journal: Sci Rep
Title: Transition state analogue of MTAP extends lifespan of APCMin/+ mice.
Volume: 11
Issue: 1
Pages: 8844
Publication
First Author: Scanlan MJ
Year: 1994
Journal: Proc Natl Acad Sci U S A
Title: Molecular cloning of fibroblast activation protein alpha, a member of the serine protease family selectively expressed in stromal fibroblasts of epithelial cancers.
Volume: 91
Issue: 12
Pages: 5657-61
Publication
First Author: Priest ND
Year: 2006
Journal: Radiat Res
Title: Relative toxicity of chronic irradiation by 45Ca beta particles and 242Cm alpha particles with respect to the production of lung tumors in CBA/Ca mice.
Volume: 166
Issue: 5
Pages: 782-93
Publication
First Author: Andreassen A
Year: 2006
Journal: Mutat Res
Title: 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) induces genetic changes in murine intestinal tumours and cells with ApcMin mutation.
Volume: 604
Issue: 1-2
Pages: 60-70
Publication
First Author: Oshima M
Year: 2001
Journal: Cancer Res
Title: Chemoprevention of intestinal polyposis in the Apcdelta716 mouse by rofecoxib, a specific cyclooxygenase-2 inhibitor.
Volume: 61
Issue: 4
Pages: 1733-40
Publication
First Author: McAndrews KM
Year: 2022
Journal: Cancer Discov
Title: Identification of Functional Heterogeneity of Carcinoma-Associated Fibroblasts with Distinct IL6-Mediated Therapy Resistance in Pancreatic Cancer.
Volume: 12
Issue: 6
Pages: 1580-1597
Publication
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
Publication
First Author: Church DM
Year: 2009
Journal: PLoS Biol
Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.
Volume: 7
Issue: 5
Pages: e1000112