| Type |
Details |
Score |
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
407
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
405
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
157
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
316
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Taylor MW |
| Year: |
1991 |
| Journal: |
FASEB J |
| Title: |
Relationship between interferon-gamma, indoleamine 2,3-dioxygenase, and tryptophan catabolism. |
| Volume: |
5 |
| Issue: |
11 |
| Pages: |
2516-22 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Suzuki T |
| Year: |
1994 |
| Journal: |
J Protein Chem |
| Title: |
Abalone myoglobins evolved from indoleamine dioxygenase: the cDNA-derived amino acid sequence of myoglobin from Nordotis madaka. |
| Volume: |
13 |
| Issue: |
1 |
| Pages: |
9-13 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Suzuki T |
| Year: |
2003 |
| Journal: |
Gene |
| Title: |
Comparison of the sequences of Turbo and Sulculus indoleamine dioxygenase-like myoglobin genes. |
| Volume: |
308 |
|
| Pages: |
89-94 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Littlejohn TK |
| Year: |
2003 |
| Journal: |
J Biol Chem |
| Title: |
Asp274 and his346 are essential for heme binding and catalytic function of human indoleamine 2,3-dioxygenase. |
| Volume: |
278 |
| Issue: |
32 |
| Pages: |
29525-31 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Yuasa HJ |
| Year: |
2011 |
| Journal: |
J Mol Evol |
| Title: |
Molecular evolution and characterization of fungal indoleamine 2,3-dioxygenases. |
| Volume: |
72 |
| Issue: |
2 |
| Pages: |
160-8 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lee YK |
| Year: |
2014 |
| Journal: |
Exp Mol Med |
| Title: |
Heme-binding-mediated negative regulation of the tryptophan metabolic enzyme indoleamine 2,3-dioxygenase 1 (IDO1) by IDO2. |
| Volume: |
46 |
|
| Pages: |
e121 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Munn DH |
| Year: |
2013 |
| Journal: |
Trends Immunol |
| Title: |
Indoleamine 2,3 dioxygenase and metabolic control of immune responses. |
| Volume: |
34 |
| Issue: |
3 |
| Pages: |
137-43 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Schmidt SV |
| Year: |
2014 |
| Journal: |
Front Immunol |
| Title: |
New Insights into IDO Biology in Bacterial and Viral Infections. |
| Volume: |
5 |
|
| Pages: |
384 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Greenall A |
| Year: |
2008 |
| Journal: |
Genome Biol |
| Title: |
A genome wide analysis of the response to uncapped telomeres in budding yeast reveals a novel role for the NAD+ biosynthetic gene BNA2 in chromosome end protection. |
| Volume: |
9 |
| Issue: |
10 |
| Pages: |
R146 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
406
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
406
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
387
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Li JS |
| Year: |
2007 |
| Journal: |
Arch Insect Biochem Physiol |
| Title: |
Biochemical mechanisms leading to tryptophan 2,3-dioxygenase activation. |
| Volume: |
64 |
| Issue: |
2 |
| Pages: |
74-87 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Sadik A |
| Year: |
2020 |
| Journal: |
Cell |
| Title: |
IL4I1 Is a Metabolic Immune Checkpoint that Activates the AHR and Promotes Tumor Progression. |
| Volume: |
182 |
| Issue: |
5 |
| Pages: |
1252-1270.e34 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Pflügler S |
| Year: |
2020 |
| Journal: |
Commun Biol |
| Title: |
IDO1+ Paneth cells promote immune escape of colorectal cancer. |
| Volume: |
3 |
| Issue: |
1 |
| Pages: |
252 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Powers RK |
| Year: |
2019 |
| Journal: |
Nat Commun |
| Title: |
Trisomy 21 activates the kynurenine pathway via increased dosage of interferon receptors. |
| Volume: |
10 |
| Issue: |
1 |
| Pages: |
4766 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Pilotte L |
| Year: |
2012 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Reversal of tumoral immune resistance by inhibition of tryptophan 2,3-dioxygenase. |
| Volume: |
109 |
| Issue: |
7 |
| Pages: |
2497-502 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Muzaki AR |
| Year: |
2016 |
| Journal: |
Mucosal Immunol |
| Title: |
Intestinal CD103(+)CD11b(-) dendritic cells restrain colitis via IFN-γ-induced anti-inflammatory response in epithelial cells. |
| Volume: |
9 |
| Issue: |
2 |
| Pages: |
336-51 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zhang D |
| Year: |
2022 |
| Journal: |
Nat Commun |
| Title: |
Kynurenine promotes neonatal heart regeneration by stimulating cardiomyocyte proliferation and cardiac angiogenesis. |
| Volume: |
13 |
| Issue: |
1 |
| Pages: |
6371 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Iacono A |
| Year: |
2020 |
| Journal: |
EMBO Rep |
| Title: |
Class IA PI3Ks regulate subcellular and functional dynamics of IDO1. |
|
|
| Pages: |
e49756 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ravishankar B |
| Year: |
2015 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
The amino acid sensor GCN2 inhibits inflammatory responses to apoptotic cells promoting tolerance and suppressing systemic autoimmunity. |
| Volume: |
112 |
| Issue: |
34 |
| Pages: |
10774-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Moritsch S |
| Year: |
2022 |
| Journal: |
Oncoimmunology |
| Title: |
Tyk2 is a tumor suppressor in colorectal cancer. |
| Volume: |
11 |
| Issue: |
1 |
| Pages: |
2127271 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Merlo LMF |
| Year: |
2022 |
| Journal: |
J Immunol |
| Title: |
The Immunomodulatory Enzyme IDO2 Mediates Autoimmune Arthritis through a Nonenzymatic Mechanism. |
| Volume: |
208 |
| Issue: |
3 |
| Pages: |
571-581 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Gurav A |
| Year: |
2015 |
| Journal: |
Biochem J |
| Title: |
Slc5a8, a Na+-coupled high-affinity transporter for short-chain fatty acids, is a conditional tumour suppressor in colon that protects against colitis and colon cancer under low-fibre dietary conditions. |
| Volume: |
469 |
| Issue: |
2 |
| Pages: |
267-78 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Yamasuge W |
| Year: |
2019 |
| Journal: |
Cancer Sci |
| Title: |
Indoleamine 2,3-dioxygenase 2 depletion suppresses tumor growth in a mouse model of Lewis lung carcinoma. |
| Volume: |
110 |
| Issue: |
10 |
| Pages: |
3061-3067 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Dai J |
| Year: |
2022 |
| Journal: |
Front Pharmacol |
| Title: |
Role of 5-HT1A-mediated upregulation of brain indoleamine 2,3 dioxygenase 1 in the reduced antidepressant and antihyperalgesic effects of fluoxetine during maintenance treatment. |
| Volume: |
13 |
|
| Pages: |
1084108 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Liang H |
| Year: |
2019 |
| Journal: |
Signal Transduct Target Ther |
| Title: |
The proatherosclerotic function of indoleamine 2, 3-dioxygenase 1 in the developmental stage of atherosclerosis. |
| Volume: |
4 |
|
| Pages: |
23 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Yuasa HJ |
| Year: |
2016 |
| Journal: |
FEBS J |
| Title: |
High l-Trp affinity of indoleamine 2,3-dioxygenase 1 is attributed to two residues located in the distal heme pocket. |
| Volume: |
283 |
| Issue: |
19 |
| Pages: |
3651-3661 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Prangtaworn P |
| Year: |
2018 |
| Journal: |
Sci Rep |
| Title: |
Tregitope-linked Refined Allergen Vaccines for Immunotherapy in Cockroach Allergy. |
| Volume: |
8 |
| Issue: |
1 |
| Pages: |
15480 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Arjunan P |
| Year: |
2018 |
| Journal: |
Sci Rep |
| Title: |
Oral Pathobiont Activates Anti-Apoptotic Pathway, Promoting both Immune Suppression and Oncogenic Cell Proliferation. |
| Volume: |
8 |
| Issue: |
1 |
| Pages: |
16607 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zhang J |
| Year: |
2019 |
| Journal: |
Front Immunol |
| Title: |
Switch of NAD Salvage to de novo Biosynthesis Sustains SIRT1-RelB-Dependent Inflammatory Tolerance. |
| Volume: |
10 |
|
| Pages: |
2358 |
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•
•
•
•
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| Publication |
| First Author: |
Renga G |
| Year: |
2020 |
| Journal: |
Life Sci Alliance |
| Title: |
Thymosin α1 protects from CTLA-4 intestinal immunopathology. |
| Volume: |
3 |
| Issue: |
10 |
|
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•
•
•
•
•
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| Publication |
| First Author: |
Yamamoto T |
| Year: |
2019 |
| Journal: |
Sci Signal |
| Title: |
Kynurenine signaling through the aryl hydrocarbon receptor maintains the undifferentiated state of human embryonic stem cells. |
| Volume: |
12 |
| Issue: |
587 |
|
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•
•
•
•
•
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| Publication |
| First Author: |
Izadpanah A |
| Year: |
2023 |
| Journal: |
Front Immunol |
| Title: |
SARS-CoV-2 infection dysregulates NAD metabolism. |
| Volume: |
14 |
|
| Pages: |
1158455 |
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•
•
•
•
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| Publication |
| First Author: |
Browne CA |
| Year: |
2012 |
| Journal: |
Neuroscience |
| Title: |
Differential lipopolysaccharide-induced immune alterations in the hippocampus of two mouse strains: effects of stress. |
| Volume: |
225 |
|
| Pages: |
237-48 |
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•
•
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| Publication |
| First Author: |
Sheng YH |
| Year: |
2022 |
| Journal: |
Cell Mol Gastroenterol Hepatol |
| Title: |
MUC1-mediated Macrophage Activation Promotes Colitis-associated Colorectal Cancer via Activating the Interleukin-6/ Signal Transducer and Activator of Transcription 3 Axis. |
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•
•
•
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•
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