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Search results 401 to 500 out of 513 for Rbl1

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Type Details Score
Publication
17257418 | J:119916
 
First Author: Yang HS
Year: 2007
Journal: BMC Dev Biol
Title: pRb-mediated control of epithelial cell proliferation and Indian hedgehog expression in mouse intestinal development.
Volume: 7
Pages: 6
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Publication
21172336 | J:170384
First Author: Fischer T
Year: 2011
Journal: Dev Biol
Title: Fgf15-mediated control of neurogenic and proneural gene expression regulates dorsal midbrain neurogenesis.
Volume: 350
Issue: 2
Pages: 496-510
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Publication
21779340 | J:175792
First Author: Jelcick AS
Year: 2011
Journal: PLoS One
Title: Genetic variations strongly influence phenotypic outcome in the mouse retina.
Volume: 6
Issue: 7
Pages: e21858
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Publication
25142465 | J:214809
First Author: Moniot B
Year: 2014
Journal: Development
Title: Prostaglandin D2 acts through the Dp2 receptor to influence male germ cell differentiation in the foetal mouse testis.
Volume: 141
Issue: 18
Pages: 3561-71
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Publication
34746147 | J:314268
 
First Author: Akagawa R
Year: 2021
Journal: Front Cell Dev Biol
Title: Alternative Functions of Cell Cycle-Related and DNA Repair Proteins in Post-mitotic Neurons.
Volume: 9
Pages: 753175
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Publication
21194568 | J:171293
First Author: Campbell GR
Year: 2011
Journal: Mol Cell Neurosci
Title: Transcription factors expressed in olfactory bulb local progenitor cells revealed by genome-wide transcriptome profiling.
Volume: 46
Issue: 2
Pages: 548-61
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Publication
22560297 | J:184521
First Author: Koss M
Year: 2012
Journal: Dev Cell
Title: Congenital asplenia in mice and humans with mutations in a Pbx/Nkx2-5/p15 module.
Volume: 22
Issue: 5
Pages: 913-26
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Publication
20059953 | J:156017
First Author: Yokoyama S
Year: 2009
Journal: Dev Cell
Title: A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58.
Volume: 17
Issue: 6
Pages: 836-48
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Publication
12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
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Publication
- | J:204739
     
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
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Publication
- | J:171409
     
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:72247
       
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Allele
Rbl1<tm1Htr> | MGI:2385659
Name: RB transcriptional corepressor like 1; targeted mutation 1, Hein te Riele
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Allele
Tg(WAPT121)66Tvd | MGI:4940590
Name: transgene insertion 66, Terry van Dyke
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Rbl1<tm1Tyj> | MGI:1857448
Name: RB transcriptional corepressor like 1; targeted mutation 1, Tyler Jacks
Allele Type: Targeted
Attribute String: Null/knockout
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Strain
MGI:3777354 | B6;129S2-Rbl1<tm1Tyj>/J
Attribute String: targeted mutation, mutant stock
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Allele
Rbl1<tm1Mru> | MGI:1857798
Name: RB transcriptional corepressor like 1; targeted mutation 1, Michael Rudnicki
Allele Type: Targeted
Attribute String: Null/knockout
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Strain
MGI:6144448 | B6D2-Tg(WAPT121)66Tvd/Nci
Attribute String: mutant stock, transgenic
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Genotype
Genotype
Symbol: Rbl1/Rbl1
Background: involves: 129S2/SvPas * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rbl1/Rbl1<+>
Background: involves: 129S2/SvPas * C57BL/6
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rbl1/Rbl1
Background: involves: 129S2/SvPas
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rbl1/Rbl1
Background: involves: 129S2/SvPas * FVB/N
Zygosity: hm
Has Mutant Allele: true
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Publication
23125361 | J:200246
First Author: Loedige I
Year: 2013
Journal: Nucleic Acids Res
Title: The mammalian TRIM-NHL protein TRIM71/LIN-41 is a repressor of mRNA function.
Volume: 41
Issue: 1
Pages: 518-32
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HT Experiment
E-GEOD-9567 | Transcription profiling of mouse whole skin from pRB deficient animals reveals that p107 acts as a tumor suppressor
Series Id: GSE9567
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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Publication
14966529 | J:88315
First Author: Simin K
Year: 2004
Journal: PLoS Biol
Title: pRb inactivation in mammary cells reveals common mechanisms for tumor initiation and progression in divergent epithelia.
Volume: 2
Issue: 2
Pages: E22
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Genotype
Genotype
Symbol: Rb1/Rb1 Rbl1/Rbl1 Tg(Pcp2-cre)756Mro/?
Background: involves: 129P2/OlaHsd * FVB
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rb1/Rb1 Rbl1/Rbl1 Tg(En2-cre)22Alj/?
Background: involves: 129P2/OlaHsd * CD-1
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rb1/Rb1 Rbl1/Rbl1<+> Tg(En2-cre)22Alj/?
Background: involves: 129P2/OlaHsd * CD-1
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rbl1/Rbl1
Background: involves: 129S4/SvJae * BALB/cJ * C57BL/6J
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rbl1/Rbl1
Background: involves: 129S4/SvJae * BALB/cJ
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rbl1/Rbl1
Background: involves: 129S4/SvJae * BALB/c * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rbl1/Rbl1
Background: involves: 129S4/SvJae * BALB/c
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rb1/Rb1 Rbl1/Rbl1 Rbl2/Rbl2
Background: involves: 129S2/SvPas * 129S4/SvJae * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Publication
21677172 | J:173537
First Author: Rocha-Sanchez SM
Year: 2011
Journal: J Neurosci
Title: Mature mice lacking Rbl2/p130 gene have supernumerary inner ear hair cells and supporting cells.
Volume: 31
Issue: 24
Pages: 8883-93
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Genotype
Genotype
Symbol: Rb1/Rb1 Rbl1/Rbl1<+> Trp53/Trp53 Tg(En2-cre)22Alj/?
Background: involves: 129P2/OlaHsd * CD-1
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rbl1/Rbl1 Tg(Pax6-cre,GFP)2Pgr/?
Background: involves: 129 * C57BL/6 * FVB/N * NMRI
Zygosity: cn
Has Mutant Allele: true
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Publication
25907958 | J:316599
 
First Author: Xie C
Year: 2015
Journal: Mol Cancer
Title: Co-deleting Pten with Rb in retinal progenitor cells in mice results in fully penetrant bilateral retinoblastomas.
Volume: 14
Pages: 93
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Publication
12204530 | -
First Author: Sherr CJ
Year: 2002
Journal: Cancer Cell
Title: The RB and p53 pathways in cancer.
Volume: 2
Issue: 2
Pages: 103-12
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Publication
11545733 | -
First Author: Thomas DM
Year: 2001
Journal: Mol Cell
Title: The retinoblastoma protein acts as a transcriptional coactivator required for osteogenic differentiation.
Volume: 8
Issue: 2
Pages: 303-16
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Protein Domain
IPR028309 | RB_fam
Type: Family
Description: This entry represents the retinoblastoma protein family, including retinoblastoma-associated protein (RB, also known as pRb, RB, p1051), retinoblastoma-like protein 1 (RBL1, also known as p107) and retinoblastoma-like protein 2 (RBL2, also known as RB2 or p130). Members of this family contain a conserved domain named the 'pocket' that interacts with the LXCXE motif found in viral proteins, such as SV40 large T antigen []. Therefore, this family is also called the pocket protein family.In humans, RB is a tumour suppressor linked to several major cancers []. RB forms complexes with E2Fs and represses gene expression by recruiting chromatin remodeling factors, such as histone deacetylases (HDACs) to E2F-responsive promoters [, ]. This interaction regulates genes necessary for DNA replication and cell cycle. Phosphorylation of RB family by CDK and cyclin complexes leads to release of the repressor complex and enables E2F-dependent gene expression []. Apart from E2Fs, RB also interacts with other transcription factors that govern cell differentiation [, ]. RBL1 and RBL2 are the components of the DREAM complex, which represses cell cycle-dependent genes in quiescent cells and plays a role in the cell cycle-dependent activation of G2/M genes [, ].
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Genotype
Genotype
Symbol: Rb1/Rb1<+> Rbl1/Rbl1
Background: involves: 129S2/SvPas * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rb1/Rb1 Rbl1/Rbl1
Background: involves: 129S2/SvPas * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rb1/Rb1<+> Rbl1/Rbl1<+>
Background: involves: 129S2/SvPas * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rbl1/Rbl1 Rbl2/Rbl2
Background: involves: 129S2/SvPas * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rbl1/Rbl1<+> Rbl2/Rbl2
Background: involves: 129S2/SvPas * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rbl1/Rbl1 Rbl2/Rbl2<+>
Background: involves: 129S2/SvPas * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rb1/Rb1 Rbl1/Rbl1 Tg(Pax6-cre,GFP)2Pgr/?
Background: involves: 129S2/SvPas * 129S4/SvJae * 129X1/SvJ * C57BL/6 * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: E2f2/E2f2 Rbl1/Rbl1 Tg(Pax6-cre,GFP)2Pgr/?
Background: involves: 129 * C57BL/6 * FVB/N * NMRI
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: E2f1/E2f1<+> Rbl1/Rbl1 Tg(Pax6-cre,GFP)2Pgr/?
Background: involves: 129 * C57BL/6 * FVB/N * NMRI
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: E2f1/E2f1 Rbl1/Rbl1 Tg(Pax6-cre,GFP)2Pgr/?
Background: involves: 129 * C57BL/6 * FVB/N * NMRI
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: E2f3/E2f3 Rbl1/Rbl1 Tg(Pax6-cre,GFP)2Pgr/?
Background: involves: 129 * C57BL/6 * FVB/N * NMRI
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rbl1/Rbl1 Tg(Chx10-EGFP/cre,-ALPP)2Clc/?
Background: involves: 129 * C57BL/6 * FVB/N * NMRI * SJL
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rb1/Rb1 Rbl1/Rbl1 Tg(Nes-cre)1Atp/?
Background: involves: 129S2/SvPas * 129S4/SvJae * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rb1/Rb1 Rbl1/Rbl1
Background: involves: 129S2/SvPas * 129S4/SvJae * BALB/c * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rb1/Rb1 Rbl1/Rbl1 Rbl2/Rbl2
Background: involves: 129 * 129S2/SvPas * 129S4/SvJae
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rbl1/Rbl1<+> Rbl2/Rbl2<+>
Background: involves: 129S2/SvPas * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rb1/Rb1 Rbl1/Rbl1 Tg(KRT14-cre)8Brn/?
Background: involves: 129 * 129S2/SvPas * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Protein
Q62017
Organism: Mus musculus/domesticus
Length: 187  
Fragment?: true
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Publication
11018009 | -
First Author: Harbour JW
Year: 2000
Journal: Genes Dev
Title: The Rb/E2F pathway: expanding roles and emerging paradigms.
Volume: 14
Issue: 19
Pages: 2393-409
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Publication
6320372 | -
First Author: Murphree AL
Year: 1984
Journal: Science
Title: Retinoblastoma: clues to human oncogenesis.
Volume: 223
Issue: 4640
Pages: 1028-33
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Publication
21665145 | J:173563
First Author: Schvartzman JM
Year: 2011
Journal: Cancer Cell
Title: Mad2 is a critical mediator of the chromosome instability observed upon Rb and p53 pathway inhibition.
Volume: 19
Issue: 6
Pages: 701-14
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Genotype
Genotype
Symbol: E2f1/E2f1 E2f3/E2f3 Rbl1/Rbl1 Tg(Pax6-cre,GFP)2Pgr/?
Background: involves: 129 * C57BL/6 * FVB/N * NMRI
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rb1/Rb1 Rbl1/Rbl1 Tg(Chx10-EGFP/cre,-ALPP)2Clc/?
Background: involves: 129 * C57BL/6N * SJL
Zygosity: cn
Has Mutant Allele: true
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Protein
Q9CT40
Organism: Mus musculus/domesticus
Length: 405  
Fragment?: true
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Protein
Q3UQT1
Organism: Mus musculus/domesticus
Length: 174  
Fragment?: true
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Genotype
Genotype
Symbol: Rb1/Rb1 Rbl1/Rbl1 Trp53/Trp53 Tg(Chx10-EGFP/cre,-ALPP)2Clc/?
Background: involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rb1/Rb1 Rbl1/Rbl1 Trp53/Trp53 Tg(Chx10-EGFP/cre,-ALPP)2Clc/?
Background: involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
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