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Search results 501 to 552 out of 552 for Bace1

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Publication

27192432 | J:248962

First Author:	Walker KR
Year:	2016
Journal:	PLoS One
Title:	Genetic Deletion of the Clathrin Adaptor GGA3 Reduces Anxiety and Alters GABAergic Transmission.
Volume:	11
Issue:	5
Pages:	e0155799

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Publication

22221883 | J:188312

First Author:	Fuso A
Year:	2012
Journal:	Neurobiol Aging
Title:	S-adenosylmethionine reduces the progress of the Alzheimer-like features induced by B-vitamin deficiency in mice.
Volume:	33
Issue:	7
Pages:	1482.e1-16

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Publication

30576233 | J:284806

First Author:	Qian Q
Year:	2019
Journal:	FASEB J
Title:	Down-regulated expression of microRNA-338-5p contributes to neuropathology in Alzheimer's disease.
Volume:	33
Issue:	3
Pages:	4404-4417

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Publication

31743728 | J:307433

First Author:	Peterman JL
Year:	2020
Journal:	Behav Brain Res
Title:	Prolonged isolation stress accelerates the onset of Alzheimer's disease-related pathology in 5xFAD mice despite running wheels and environmental enrichment.
Volume:	379

Pages:	112366

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Publication

25378159 | J:238184

First Author:	Zhang J
Year:	2014
Journal:	J Neurosci
Title:	Synaptic and cognitive improvements by inhibition of 2-AG metabolism are through upregulation of microRNA-188-3p in a mouse model of Alzheimer's disease.
Volume:	34
Issue:	45
Pages:	14919-33

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Publication

34232542 | J:350384

First Author:	Liu J
Year:	2021
Journal:	Cell Prolif
Title:	Infusion of hESC derived Immunity-and-matrix regulatory cells improves cognitive ability in early-stage AD mice.
Volume:	54
Issue:	8
Pages:	e13085

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Publication

24305806 | J:255339

First Author:	Herskowitz JH
Year:	2013
Journal:	J Neurosci
Title:	Pharmacologic inhibition of ROCK2 suppresses amyloid-β production in an Alzheimer's disease mouse model.
Volume:	33
Issue:	49
Pages:	19086-98

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Publication

29033830 | J:276673

First Author:	Guglielmotto M
Year:	2017
Journal:	Front Aging Neurosci
Title:	The Decrease of Uch-L1 Activity Is a Common Mechanism Responsible for Aβ 42 Accumulation in Alzheimer's and Vascular Disease.
Volume:	9

Pages:	320

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Publication

36427805 | J:344587

First Author:	Feng W
Year:	2023
Journal:	Brain Behav Immun
Title:	B lymphocytes ameliorate Alzheimer's disease-like neuropathology via interleukin-35.
Volume:	108

Pages:	16-31

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Publication

32918367 | J:352666

First Author:	Yao Y
Year:	2020
Journal:	Alzheimers Dement
Title:	Correction of microtubule defects within Aβ plaque-associated dystrophic axons results in lowered Aβ release and plaque deposition.
Volume:	16
Issue:	10
Pages:	1345-1357

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Publication

27312991 | J:264480

First Author:	Kolisnyk B
Year:	2017
Journal:	Cereb Cortex
Title:	Cholinergic Surveillance over Hippocampal RNA Metabolism and Alzheimer's-Like Pathology.
Volume:	27
Issue:	7
Pages:	3553-3567

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Publication

27993242 | J:239385

First Author:	Gannon PJ
Year:	2017
Journal:	Am J Pathol
Title:	HIV Protease Inhibitors Alter Amyloid Precursor Protein Processing via β-Site Amyloid Precursor Protein Cleaving Enzyme-1 Translational Up-Regulation.
Volume:	187
Issue:	1
Pages:	91-109

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Publication

22294787 | J:237165

First Author:	Lakshmana MK
Year:	2012
Journal:	FASEB J
Title:	Role of RanBP9 on amyloidogenic processing of APP and synaptic protein levels in the mouse brain.
Volume:	26
Issue:	5
Pages:	2072-83

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Publication

23259059 | J:192876

First Author:	Wang CL
Year:	2012
Journal:	Biol Open
Title:	VPS35 regulates developing mouse hippocampal neuronal morphogenesis by promoting retrograde trafficking of BACE1.
Volume:	1
Issue:	12
Pages:	1248-57

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Publication

25316600 | J:218405

First Author:	Cox CJ
Year:	2015
Journal:	Neurobiol Aging
Title:	Dietary (-)-epicatechin as a potent inhibitor of βγ-secretase amyloid precursor protein processing.
Volume:	36
Issue:	1
Pages:	178-87

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Publication

39122814 | J:353365

First Author:	Honda K
Year:	2024
Journal:	Sci Rep
Title:	Suppression of the amyloidogenic metabolism of APP and the accumulation of Aβ by alcadein α in the brain during aging.
Volume:	14
Issue:	1
Pages:	18471

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Publication

34379812 | J:353065

First Author:	Hata S
Year:	2021
Journal:	J Neurochem
Title:	Suppression of amyloid-β secretion from neurons by cis-9, trans-11-octadecadienoic acid, an isomer of conjugated linoleic acid.
Volume:	159
Issue:	3
Pages:	603-617

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Publication

35008980 | J:317411

First Author:	Swingler TE
Year:	2022
Journal:	Int J Mol Sci
Title:	The microRNA-455 Null Mouse Has Memory Deficit and Increased Anxiety, Targeting Key Genes Involved in Alzheimer's Disease.
Volume:	23
Issue:	1

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Publication

31838721 | J:319902

First Author:	Czarnek M
Year:	2020
Journal:	Mol Neurobiol
Title:	Proteolytic Processing of Neuregulin 2.
Volume:	57
Issue:	4
Pages:	1799-1813

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Publication

27036734 | J:232854

First Author:	Kuzuya A
Year:	2016
Journal:	BMC Biol
Title:	Identification of the novel activity-driven interaction between synaptotagmin 1 and presenilin 1 links calcium, synapse, and amyloid beta.
Volume:	14

Pages:	25

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Publication

30086173 | J:273543

First Author:	Takasugi N
Year:	2018
Journal:	PLoS One
Title:	TMEM30A is a candidate interacting partner for the β-carboxyl-terminal fragment of amyloid-β precursor protein in endosomes.
Volume:	13
Issue:	8
Pages:	e0200988

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Publication

18032377 | J:131340

First Author:	Zhao B
Year:	2008
Journal:	J Biol Chem
Title:	Identification of gamma-secretase inhibitor potency determinants on presenilin.
Volume:	283
Issue:	5
Pages:	2927-38

•

Publication

23658180 | J:198432

First Author:	Li W
Year:	2013
Journal:	J Neurosci
Title:	Elevation of brain magnesium prevents and reverses cognitive deficits and synaptic loss in Alzheimer's disease mouse model.
Volume:	33
Issue:	19
Pages:	8423-41

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Publication

26694839 | J:230836

First Author:	Chen AC
Year:	2015
Journal:	J Cell Biol
Title:	Physical and functional interaction between the α- and γ-secretases: A new model of regulated intramembrane proteolysis.
Volume:	211
Issue:	6
Pages:	1157-76

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Publication

27407168 | J:245146

First Author:	Toh WH
Year:	2016
Journal:	Biochem J
Title:	Dysregulation of intracellular trafficking and endosomal sorting in Alzheimer's disease: controversies and unanswered questions.
Volume:	473
Issue:	14
Pages:	1977-93

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Publication

24210810 | J:283486

First Author:	Luo X
Year:	2014
Journal:	Biol Psychiatry
Title:	Reversible overexpression of bace1-cleaved neuregulin-1 N-terminal fragment induces schizophrenia-like phenotypes in mice.
Volume:	76
Issue:	2
Pages:	120-7

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Publication

28129943 | J:282480

First Author:	Zhu K
Year:	2018
Journal:	Biol Psychiatry
Title:	Beta-Site Amyloid Precursor Protein Cleaving Enzyme 1 Inhibition Impairs Synaptic Plasticity via Seizure Protein 6.
Volume:	83
Issue:	5
Pages:	428-437

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Publication

32700357 | J:294300

First Author:	Wang Y
Year:	2020
Journal:	Aging Cell
Title:	RTN4B-mediated suppression of Sirtuin 2 activity ameliorates β-amyloid pathology and cognitive impairment in Alzheimer's disease mouse model.


Pages:	e13194

•

Publication

31908000 | J:296932

First Author:	Rudan Njavro J
Year:	2020
Journal:	FASEB J
Title:	Mouse brain proteomics establishes MDGA1 and CACHD1 as in vivo substrates of the Alzheimer protease BACE1.
Volume:	34
Issue:	2
Pages:	2465-2482

•

Publication

26115702 | J:315121

First Author:	Feng T
Year:	2016
Journal:	Mol Neurobiol
Title:	SNX15 Regulates Cell Surface Recycling of APP and Aβ Generation.
Volume:	53
Issue:	6
Pages:	3690-3701

•

Publication

21127294 | J:178507

First Author:	Austin SA
Year:	2010
Journal:	Circ Res
Title:	Endothelial nitric oxide modulates expression and processing of amyloid precursor protein.
Volume:	107
Issue:	12
Pages:	1498-502

•

Publication

23155407 | J:195586

First Author:	Yan XX
Year:	2012
Journal:	PLoS One
Title:	Chronic temporal lobe epilepsy is associated with enhanced Alzheimer-like neuropathology in 3×Tg-AD mice.
Volume:	7
Issue:	11
Pages:	e48782

•

Publication

34903570 | J:341283

First Author:	Cui J
Year:	2022
Journal:	J Neurosci
Title:	Sex-Specific Regulation of β-Secretase: A Novel Estrogen Response Element (ERE)-Dependent Mechanism in Alzheimer's Disease.
Volume:	42
Issue:	6
Pages:	1154-1165

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Publication

32032729 | J:297609

First Author:	Borreca A
Year:	2020
Journal:	Neurobiol Dis
Title:	Transient upregulation of translational efficiency in prodromal and early symptomatic Tg2576 mice contributes to Aβ pathology.
Volume:	139

Pages:	104787

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Publication

23312803 | J:203369

First Author:	Gong B
Year:	2013
Journal:	Neurobiol Aging
Title:	Nicotinamide riboside restores cognition through an upregulation of proliferator-activated receptor-γ coactivator 1α regulated β-secretase 1 degradation and mitochondrial gene expression in Alzheimer's mouse models.
Volume:	34
Issue:	6
Pages:	1581-8

•

Publication

25474204 | J:225685

First Author:	Lysenko LV
Year:	2014
Journal:	PLoS One
Title:	Monoacylglycerol lipase inhibitor JZL184 improves behavior and neural properties in Ts65Dn mice, a model of down syndrome.
Volume:	9
Issue:	12
Pages:	e114521

•

Publication

26147692 | J:252327

First Author:	Dorresteijn B
Year:	2015
Journal:	FEBS J
Title:	Camelid heavy chain only antibody fragment domain against β-site of amyloid precursor protein cleaving enzyme 1 inhibits β-secretase activity in vitro and in vivo.
Volume:	282
Issue:	18
Pages:	3618-31

•

Publication

39026992 | J:352237

First Author:	Wang J
Year:	2024
Journal:	Front Aging Neurosci
Title:	ACOT7, a candidate and novel serum biomarker of Alzheimer's disease.
Volume:	16

Pages:	1345668

•

Publication

32070713 | J:292692

First Author:	Liu B
Year:	2020
Journal:	Exp Neurol
Title:	AdipoRon improves cognitive dysfunction of Alzheimer's disease and rescues impaired neural stem cell proliferation through AdipoR1/AMPK pathway.
Volume:	327

Pages:	113249

•

Publication

28432138 | J:273166

First Author:	Baek SH
Year:	2017
Journal:	J Neurosci
Title:	Inhibition of Drp1 Ameliorates Synaptic Depression, Aβ Deposition, and Cognitive Impairment in an Alzheimer's Disease Model.
Volume:	37
Issue:	20
Pages:	5099-5110

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Publication

30249297 | J:277619

First Author:	Nguyen TV
Year:	2018
Journal:	Acta Neuropathol Commun
Title:	Alzheimer's associated amyloid and tau deposition co-localizes with a homeostatic myelin repair pathway in two mouse models of post-stroke mixed dementia.
Volume:	6
Issue:	1
Pages:	100

•

Publication

22634014 | J:185356

First Author:	Wang J
Year:	2012
Journal:	Biochem Biophys Res Commun
Title:	Elevated amyloid β production in senescent retinal pigment epithelium, a possible mechanism of subretinal deposition of amyloid β in age-related macular degeneration.
Volume:	423
Issue:	1
Pages:	73-8

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Publication

22824191 | J:192663

First Author:	Dobarro M
Year:	2013
Journal:	Neuropharmacology
Title:	Propranolol restores cognitive deficits and improves amyloid and Tau pathologies in a senescence-accelerated mouse model.
Volume:	64

Pages:	137-44

•

Publication

23410038 | J:198164

First Author:	Broder C
Year:	2013
Journal:	Biochem J
Title:	The metalloproteases meprin α and meprin β: unique enzymes in inflammation, neurodegeneration, cancer and fibrosis.
Volume:	450
Issue:	2
Pages:	253-64

•

Publication

24844149 | J:214313

First Author:	Albers S
Year:	2014
Journal:	Neurobiol Dis
Title:	Nuclear 82-kDa choline acetyltransferase decreases amyloidogenic APP metabolism in neurons from APP/PS1 transgenic mice.
Volume:	69

Pages:	32-42

•

Publication

26593275 | J:318324

First Author:	Hwang CJ
Year:	2016
Journal:	Brain Behav Immun
Title:	Acceleration of amyloidogenesis and memory impairment by estrogen deficiency through NF-κB dependent beta-secretase activation in presenilin 2 mutant mice.
Volume:	53

Pages:	113-122

•

Protein

Q9JL18

Organism:	Mus musculus/domesticus
Length:	514
Fragment?:	false

•

Protein

A0A0R4J0I8

Organism:	Mus musculus/domesticus
Length:	514
Fragment?:	false

•

Publication

31043483 | J:277174

First Author:	Jiang Y
Year:	2019
Journal:	J Neurosci
Title:	Lysosomal Dysfunction in Down Syndrome Is APP-Dependent and Mediated by APP-βCTF (C99).
Volume:	39
Issue:	27
Pages:	5255-5268

•

Publication

36603748 | J:333422

First Author:	Tohumeken S
Year:	2023
Journal:	Neurobiol Dis
Title:	Neuronal deletion of nSMase2 reduces the production of Aβ and directly protects neurons.
Volume:	177

Pages:	105987

•

Publication

33076948 | J:303244

First Author:	Serneels L
Year:	2020
Journal:	Mol Neurodegener
Title:	Modeling the β-secretase cleavage site and humanizing amyloid-beta precursor protein in rat and mouse to study Alzheimer's disease.
Volume:	15
Issue:	1
Pages:	60

•

Publication

36192747 | J:331899

First Author:	Wouters Y
Year:	2022
Journal:	Fluids Barriers CNS
Title:	VHHs as tools for therapeutic protein delivery to the central nervous system.
Volume:	19
Issue:	1
Pages:	79

•

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